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cGMP-dependent protein kinase activity - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:cGMP-dependent protein kinase activity
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Accession:GO:0004692 term browser browse the term
Definition:cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
Comment:This reaction requires the presence of cGMP.
Synonyms:related_synonym: 3':5'-cyclic GMP-dependent protein kinase activity;   ATP:protein phosphotransferase (cGMP-dependent) activity;   PKG;   PKG 1alpha;   PKG 1beta;   PKG II;   STK23;   cGMP-dependent protein kinase ibeta activity;   guanosine 3':5'-cyclic monophosphate-dependent protein kinase activity
 xref: EC:2.7.11.12;   reactome:R-HSA-1475422 "PTPS is phosphorylated by cGMP-dependant protein kinase II";   reactome:R-HSA-1497853 "Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II";   reactome:R-HSA-418442 "PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release";   reactome:R-HSA-418549 "PKG1 phosphorylates BK channels"

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cGMP-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkg1 protein kinase cGMP-dependent 1 enables ISO (PMID:21402151)
(PMID:10671526)		 UniProt PMID:10671526 PMID:21402151 NCBI chrNW_004955425:6,176,335...7,335,867
Ensembl chrNW_004955425:6,176,432...7,331,446 		JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 enables ISO (PMID:33106379)
(PMID:10531334)		 RGD
UniProt
MGI		 PMID:7589584 PMID:10531334 PMID:33106379 RGD:7777109 NCBI chrNW_004955433:5,286,594...5,387,571
Ensembl chrNW_004955433:5,286,153...5,491,924 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 14382
    catalytic activity 3811
      catalytic activity, acting on a protein 1642
        protein kinase activity 455
          protein serine/threonine kinase activity 319
            cyclic nucleotide-dependent protein kinase activity 5
              cGMP-dependent protein kinase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 14382
    catalytic activity 3811
      transferase activity 1696
        transferase activity, transferring phosphorus-containing groups 693
          kinase activity 587
            protein kinase activity 455
              protein serine/threonine kinase activity 319
                cyclic nucleotide-dependent protein kinase activity 5
                  cGMP-dependent protein kinase activity 2
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