kynurenine 3-monooxygenase activity - Ontology Report

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Term:	kynurenine 3-monooxygenase activity	go back to main search page
Accession:	GO:0004502	browse the term
Definition:	Catalysis of the reaction: L-kynurenine + H+ + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP+.
Synonyms:	exact_synonym:	kynurenine 3-hydroxylase activity
	related_synonym:	L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating); L-kynurenine-3-hydroxylase activity; kynurenine hydroxylase activity
	xref:	EC:1.14.13.9; KEGG_REACTION:R01960; MetaCyc:KYNURENINE-3-MONOOXYGENASE-RXN; RHEA:20545; reactome:R-HSA-71200 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O"

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Genes (1)

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KMO

kynurenine 3-monooxygenase

enables

GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000116 GO_REF:0000118 RGD:2290309 RGD:2290310 RGD:2290313

NCBI chr25:78,611,194...78,670,314
Ensembl chr25:78,628,757...78,670,181

Term paths to the root

Path 1
Term	Annotations
molecular_function	18111
catalytic activity	5515
oxidoreductase activity	714
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	189
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	33
kynurenine 3-monooxygenase activity	1

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