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ONTOLOGY REPORT - ANNOTATIONS
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Term:
choline O-acetyltransferase activity
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Accession:
GO:0004102
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Definition:
Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA.
Synonyms:
related_synonym:
CHOACTase activity; acetyl-CoA:choline O-acetyltransferase activity; choline acetylase activity; choline acetyltransferase activity
xref:
EC:2.3.1.6; KEGG_REACTION:R01023; MetaCyc:CHOLINE-O-ACETYLTRANSFERASE-RXN; RHEA:18821; reactome:R-HSA-264622 "Cho is acetylated to AcCho by CHAT"
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Genes (1)
choline O-acetyltransferase activity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
CHAT
choline O-acetyltransferase
enables
ISO
TAS
IEA
IBA
rostral-caudal differences in enzyme activity in the superior colliculus
activity varied considerably between different layers of the cerebellar vermis
RGD
Reactome
UniProt
RHEA
GO_Central
PMID:126256
PMID:334962
PMID:4008917
PMID:6619842
PMID:6854006
GO_REF:0000003 GO_REF:0000033 GO_REF:0000116
RGD:1600852
RGD:2301195
RGD:2301197
RGD:2301199
RGD:2301203
Reactome:R-HSA-264622
NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942
Term paths to the root
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Path 1
Term
Annotations
molecular_function
19683
catalytic activity
6023
transferase activity
2450
acyltransferase activity
759
acyltransferase activity, transferring groups other than amino-acyl groups
239
acetyltransferase activity
101
O-acetyltransferase activity
9
choline O-acetyltransferase activity
1