Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:NAD+-protein poly-ADP-ribosyltransferase activity
go back to main search page
Accession:GO:0003950 term browser browse the term
Definition:Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
Synonyms:exact_synonym: NAD ADP-ribosyltransferase activity
 related_synonym: ADP-ribosyltransferase (polymerizing) activity;   NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity;   poly(ADP-ribose) synthase activity;   poly(ADP-ribose) synthetase activity;   poly(ADP-ribose)polymerase activity;   poly(adenosine diphosphate ribose) polymerase activity
 xref: EC:2.4.2.30;   MetaCyc:NAD+-ADP-RIBOSYLTRANSFERASE-RXN;   Reactome:R-HSA-9686061 "Nucleoprotein is ADP-ribosylated";   Reactome:R-HSA-9729279 "Nucleoprotein is ADP-ribosylated";   reactome:R-HSA-2187325 "PARP1 ADP-ribosylates SMAD3 and SMAD4";   reactome:R-HSA-3640858 "Tankyrase ADP-ribosylates AXIN";   reactome:R-HSA-5651723 "PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate";   reactome:R-HSA-5687653 "PARP1,PARP2 dimers bound to MMEJ sites autoPARylate";   reactome:R-HSA-5688276 "SIRT4 transfers ADPRib to GLUD";   reactome:R-HSA-8938073 "PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation)";   reactome:R-HSA-8948800 "TNKS and TNKS2 PARylate PTEN"

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
NAD+-protein poly-ADP-ribosyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Art1 ADP-ribosyltransferase 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936498:1,230,886...1,241,160
Ensembl chrNW_004936498:1,227,131...1,241,088 		JBrowse link
G Art3 ADP-ribosyltransferase 3 (inactive) enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936676:81,536...131,491
Ensembl chrNW_004936676:52,474...129,320 		JBrowse link
G Art4 ADP-ribosyltransferase 4 (inactive) (Dombrock blood group) enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936587:2,634,459...2,647,265
Ensembl chrNW_004936587:2,634,435...2,647,159 		JBrowse link
G Art5 ADP-ribosyltransferase 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936498:1,243,040...1,246,255
Ensembl chrNW_004936498:1,241,547...1,244,958 		JBrowse link
G LOC101962583 protein mono-ADP-ribosyltransferase PARP14 enables IEA Ensembl
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936536:8,923,398...8,976,583
Ensembl chrNW_004936536:8,923,411...8,974,283 		JBrowse link
G LOC101967560 T-cell ecto-ADP-ribosyltransferase 2-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936498:1,789,795...1,808,364 JBrowse link
G LOC101976814 T-cell ecto-ADP-ribosyltransferase 1-like enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004937741:2,022...24,407 JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 enables ISO
IEA		 RGD
TreeGrafter
InterPro
UniProt
Ensembl		 PMID:15857403 PMID:16302026 GO_REF:0000002 GO_REF:0000003 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:1601079 RGD:1601082 NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642 		JBrowse link
G Parp11 poly(ADP-ribose) polymerase family member 11 enables IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936606:4,062,301...4,120,389
Ensembl chrNW_004936606:4,063,171...4,120,397 		JBrowse link
G Parp12 poly(ADP-ribose) polymerase family member 12 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936592:4,195,931...4,233,304
Ensembl chrNW_004936592:4,196,753...4,228,287 		JBrowse link
G Parp16 poly(ADP-ribose) polymerase family member 16 enables IEA Ensembl
TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936471:25,561,136...25,580,801
Ensembl chrNW_004936471:25,562,250...25,580,587 		JBrowse link
G Parp2 poly(ADP-ribose) polymerase 2 enables IEA InterPro
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936877:554,969...564,905
Ensembl chrNW_004936877:554,473...564,903 		JBrowse link
G Parp3 poly(ADP-ribose) polymerase family member 3 enables IEA UniProt
Ensembl
InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936529:3,291,282...3,297,581
Ensembl chrNW_004936529:3,291,269...3,299,992 		JBrowse link
G Parp4 poly(ADP-ribose) polymerase family member 4 enables IEA Ensembl
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936720:2,049,045...2,138,649
Ensembl chrNW_004936720:2,048,455...2,119,662 		JBrowse link
G Parp6 poly(ADP-ribose) polymerase family member 6 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004936471:31,625,231...31,656,204
Ensembl chrNW_004936471:31,625,231...31,655,208 		JBrowse link
G Parp8 poly(ADP-ribose) polymerase family member 8 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 NCBI chrNW_004936480:16,297,110...16,465,178
Ensembl chrNW_004936480:16,296,401...16,465,506 		JBrowse link
G Parp9 poly(ADP-ribose) polymerase family member 9 NOT|enables ISO
IEA		 (PMID:16061477) UniProt
TreeGrafter
Ensembl
InterPro		 PMID:16061477 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936536:8,806,824...8,845,099
Ensembl chrNW_004936536:8,806,818...8,840,746 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936499:6,691,758...6,698,515
Ensembl chrNW_004936499:6,691,476...6,702,986 		JBrowse link
G Sirt2 sirtuin 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936661:1,828,868...1,849,892
Ensembl chrNW_004936661:1,828,831...1,850,000 		JBrowse link
G Sirt4 sirtuin 4 enables IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936668:628,875...633,425
Ensembl chrNW_004936668:626,938...633,466 		JBrowse link
G Tiparp TCDD inducible poly(ADP-ribose) polymerase enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936519:3,683,972...3,712,081
Ensembl chrNW_004936519:3,684,515...3,712,081 		JBrowse link
G Tnks tankyrase enables IEA Ensembl
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936573:788,909...993,453
Ensembl chrNW_004936573:794,184...994,247 		JBrowse link
G Tnks2 tankyrase 2 enables IEA UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936601:2,776,338...2,837,703
Ensembl chrNW_004936601:2,776,345...2,837,707 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 NOT|enables ISO
IEA		 (PMID:25635049) UniProt
InterPro		 PMID:25635049 GO_REF:0000002 NCBI chrNW_004936592:3,321,564...3,379,015
Ensembl chrNW_004936592:3,321,454...3,358,983 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17143
    catalytic activity 5307
      catalytic activity, acting on a protein 2172
        NAD+-protein ADP-ribosyltransferase activity 27
          NAD+-protein poly-ADP-ribosyltransferase activity 24
Path 2
Term Annotations click to browse term
  molecular_function 17143
    catalytic activity 5307
      transferase activity 2139
        glycosyltransferase activity 260
          pentosyltransferase activity 54
            NAD+-protein ADP-ribosyltransferase activity 27
              NAD+-protein poly-ADP-ribosyltransferase activity 24
paths to the root