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ONTOLOGY REPORT - ANNOTATIONS

Term:platelet degranulation
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Accession:GO:0002576 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
Synonyms:exact_synonym: platelet exocytosis
 xref: Reactome:R-HSA-114608 "Platelet degranulation"

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platelet degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
G Plek pleckstrin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624762:4,939,683...4,967,327
Ensembl chrNW_004624762:4,939,599...4,967,371 		JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO (PMID:12773094) UniProt PMID:12773094 NCBI chrNW_004624760:7,843,741...7,914,444
Ensembl chrNW_004624760:7,842,640...7,914,484 		JBrowse link
G Tph1 tryptophan hydroxylase 1 involved_in ISO (PMID:14697203) UniProt PMID:14697203 NCBI chrNW_004624766:9,629,951...9,687,772
Ensembl chrNW_004624766:9,629,849...9,668,393 		JBrowse link
protein secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624762:4,939,683...4,967,327
Ensembl chrNW_004624762:4,939,599...4,967,371 		JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig involved_in ISO (PMID:9171347) UniProt PMID:9171347 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034 		JBrowse link
G P2rx1 purinergic receptor P2X 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12913094) Ensembl
MGI		 PMID:12913094 GO_REF:0000107 NCBI chrNW_004624786:6,503,367...6,520,802
Ensembl chrNW_004624786:6,504,250...6,521,821 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17660
    cellular process 17238
      cellular localization 3431
        establishment of localization in cell 1996
          platelet degranulation 7
            histamine secretion by platelet 0
            protein secretion by platelet 1
            serotonin secretion by platelet 3
Path 2
Term Annotations click to browse term
  biological_process 17660
    localization 5199
      establishment of localization 4570
        transport 4246
          export from cell 1011
            secretion by cell 943
              exocytosis 364
                regulated exocytosis 254
                  platelet degranulation 7
                    histamine secretion by platelet 0
                    protein secretion by platelet 1
                    serotonin secretion by platelet 3
paths to the root