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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Malignant Carcinoid Syndrome
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Accession:DOID:9005598 term browser browse the term
Definition:A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed)
Synonyms:exact_synonym: Malignant Carcinoid Syndromes
 primary_id: MESH:D008303
 xref: EFO:1000852


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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19106
    syndrome 11278
      Malignant Carcinoid Syndrome 0
        Carcinoid Heart Disease 0
Path 2
Term Annotations click to browse term
  disease 19106
    disease of cellular proliferation 7915
      Neoplasms by Site 7371
        organ system cancer 5529
          nervous system cancer 1001
            neuroectodermal tumor 483
              neuroendocrine tumor 231
                Carcinoid Tumor 28
                  Malignant Carcinoid Syndrome 0
                    Carcinoid Heart Disease 0
paths to the root