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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Granuloma, Foreign-Body
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Accession:DOID:9003615 term browser browse the term
Definition:Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.
Synonyms:exact_synonym: Foreign-Body Granulomas
 primary_id: MESH:D015745;   RDO:0006915

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Granuloma, Foreign-Body term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr9 toll like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19797157 NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14336
    Pathological Conditions, Signs and Symptoms 11318
      Pathologic Processes 7187
        Granuloma 29
          Granuloma, Foreign-Body 1
Path 2
Term Annotations click to browse term
  disease 14336
    disease of anatomical entity 14029
      Immune & Inflammatory Diseases 4835
        immune system disease 4296
          lymphatic system disease 1569
            lymphoproliferative syndrome 994
              Granuloma 29
                Granuloma, Foreign-Body 1
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