Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:neurodegenerative disease
go back to main search page
Accession:DOID:1289 term browser browse the term
Definition:A central nervous system disease that results in the progressive deterioration of function or structure of neurons. (DO)
Synonyms:exact_synonym: Degenerative Neurologic Disease;   Degenerative Neurologic Disorder;   Nervous System Degenerative Diseases;   Neurodegenerative Diseases;   Neurodegenerative Disorder;   Neurodegenerative Disorders;   central nervous system degenerative diseases;   degenerative disease;   degenerative neurologic diseases;   degenerative neurologic disorders;   neurologic degenerative condition;   neurologic degenerative conditions;   spinal cord degenerative diseases
 narrow_synonym: Neurodegenerative illness progressing to crippling dystonia and death with relentless cerebral atrophy;   progressive neurodegenerative disease;   severe cystic degeneration of the brain;   subacute myelo-opticoneuropathy
 broad_synonym: TMEM63B-ASSOCIATED DISORDER
 primary_id: MESH:D019636
 xref: EFO:0005772;   EFO:0020919;   ICD10CM:G31.9;   NCI:C27090
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:


Your selection has 4921 annotated objects. The maximum number of objects that can be shown is 2000. The list is too large to display.

  • Select a more specific term using the term browser
  • Download the entire list for this term
  • Display annotations for this term only (exclude descendants)


    • Term paths to the root
    Path 1
    Term Annotations click to browse term
      disease 16177
        disease of anatomical entity 15790
          nervous system disease 13691
            neurodegenerative disease 4921
              BRAIN ABNORMALITIES, NEURODEGENERATION, AND DYSOSTEOSCLEROSIS 1
              Childhood-Onset Neurodegeneration with Cerebellar Atrophy 1
              Childhood-onset Neurodegeneration with Ataxia, Tremor, Optic Atrophy, and Cognitive Decline 1
              Childhood-onset Neurodegeneration with Hypotonia, Respiratory Insufficiency and Brain Imaging Abnormalities 1
              FINCA Syndrome 1
              Feigenbaum Bergeron Richardson Syndrome 0
              Huntington's disease-like 2 1
              Idiopathic Basal Ganglia Calcification 1 11
              Idiopathic Basal Ganglia Calcification 6 1
              Idiopathic Basal Ganglia Calcification 7 1
              LEUKOENCEPHALOPATHY, DEVELOPMENTAL DELAY, AND EPISODIC NEUROLOGIC REGRESSION SYNDROME 1
              NEURODEGENERATION AND SEIZURES DUE TO COPPER TRANSPORT DEFECT 1
              NEURODEGENERATION WITH DEVELOPMENTAL DELAY, EARLY RESPIRATORY FAILURE, MYOCLONIC SEIZURES, AND BRAIN ABNORMALITIES 1
              NEURODEGENERATION, CHILDHOOD-ONSET, WITH CEREBELLAR ATAXIA AND COGNITIVE DECLINE 1
              NEURODEGENERATION, CHILDHOOD-ONSET, WITH MULTISYSTEM INVOLVEMENT DUE TO MITOCHONDRIAL DYSFUNCTION 1
              NEURODEGENERATION, CHILDHOOD-ONSET, WITH PROGRESSIVE MICROCEPHALY 1
              NEURODEGENERATION, EARLY-ONSET, WITH CHOREOATHETOID MOVEMENTS AND MICROCYTIC ANEMIA 1
              NEURODEGENERATION, INFANTILE-ONSET, BIOTIN-RESPONSIVE 1
              Nervous System Heredodegenerative Disorders + 3392
              Nervous System Paraneoplastic Syndromes + 19
              Neurodegeneration with Ataxia and Late-Onset Optic Atrophy 1
              PEHO syndrome 4
              Radiation Sensitivity Chromosome Instability Syndrome, Autosomal Dominant 0
              Recurrent Metabolic Crises with Variable Encephalomyopathic Features and Neurologic Regression 1
              SEIZURES, EARLY-ONSET, WITH NEURODEGENERATION AND BRAIN CALCIFICATIONS 1
              Spastic Pseudosclerosis 0
              Subacute Combined Degeneration 2
              TDP-43 Proteinopathies + 433
              aceruloplasminemia 15
              agenesis of the corpus callosum with peripheral neuropathy 5
              childhood-onset neurodegeneration with brain atrophy 1
              demyelinating disease + 443
              eye degenerative disease + 868
              hereditary ataxia + 650
              motor neuron disease + 547
              multiple system atrophy + 41
              myoclonic cerebellar dyssynergia + 0
              neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset 2
              neurodegeneration with brain iron accumulation + 190
              neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures 1
              neuronal intranuclear inclusion disease 1
              olivopontocerebellar atrophy + 22
              plexopathy 0
              pontocerebellar hypoplasia + 32
              postpoliomyelitis syndrome 0
              primary cerebellar degeneration + 610
              prion disease + 108
              secondary Parkinson disease + 18
              stress-induced childhood-onset neurodegeneration with variable ataxia and seizures 1
              synucleinopathy + 403
              tauopathy + 506
    Path 2
    Term Annotations click to browse term
      disease 16177
        disease of anatomical entity 15790
          nervous system disease 13691
            central nervous system disease 12273
              neurodegenerative disease 4921
                BRAIN ABNORMALITIES, NEURODEGENERATION, AND DYSOSTEOSCLEROSIS 1
                Childhood-Onset Neurodegeneration with Cerebellar Atrophy 1
                Childhood-onset Neurodegeneration with Ataxia, Tremor, Optic Atrophy, and Cognitive Decline 1
                Childhood-onset Neurodegeneration with Hypotonia, Respiratory Insufficiency and Brain Imaging Abnormalities 1
                FINCA Syndrome 1
                Feigenbaum Bergeron Richardson Syndrome 0
                Huntington's disease-like 2 1
                Idiopathic Basal Ganglia Calcification 1 11
                Idiopathic Basal Ganglia Calcification 6 1
                Idiopathic Basal Ganglia Calcification 7 1
                LEUKOENCEPHALOPATHY, DEVELOPMENTAL DELAY, AND EPISODIC NEUROLOGIC REGRESSION SYNDROME 1
                NEURODEGENERATION AND SEIZURES DUE TO COPPER TRANSPORT DEFECT 1
                NEURODEGENERATION WITH DEVELOPMENTAL DELAY, EARLY RESPIRATORY FAILURE, MYOCLONIC SEIZURES, AND BRAIN ABNORMALITIES 1
                NEURODEGENERATION, CHILDHOOD-ONSET, WITH CEREBELLAR ATAXIA AND COGNITIVE DECLINE 1
                NEURODEGENERATION, CHILDHOOD-ONSET, WITH MULTISYSTEM INVOLVEMENT DUE TO MITOCHONDRIAL DYSFUNCTION 1
                NEURODEGENERATION, CHILDHOOD-ONSET, WITH PROGRESSIVE MICROCEPHALY 1
                NEURODEGENERATION, EARLY-ONSET, WITH CHOREOATHETOID MOVEMENTS AND MICROCYTIC ANEMIA 1
                NEURODEGENERATION, INFANTILE-ONSET, BIOTIN-RESPONSIVE 1
                Nervous System Heredodegenerative Disorders + 3392
                Nervous System Paraneoplastic Syndromes + 19
                Neurodegeneration with Ataxia and Late-Onset Optic Atrophy 1
                PEHO syndrome 4
                Radiation Sensitivity Chromosome Instability Syndrome, Autosomal Dominant 0
                Recurrent Metabolic Crises with Variable Encephalomyopathic Features and Neurologic Regression 1
                SEIZURES, EARLY-ONSET, WITH NEURODEGENERATION AND BRAIN CALCIFICATIONS 1
                Spastic Pseudosclerosis 0
                Subacute Combined Degeneration 2
                TDP-43 Proteinopathies + 433
                aceruloplasminemia 15
                agenesis of the corpus callosum with peripheral neuropathy 5
                childhood-onset neurodegeneration with brain atrophy 1
                demyelinating disease + 443
                eye degenerative disease + 868
                hereditary ataxia + 650
                motor neuron disease + 547
                multiple system atrophy + 41
                myoclonic cerebellar dyssynergia + 0
                neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset 2
                neurodegeneration with brain iron accumulation + 190
                neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures 1
                neuronal intranuclear inclusion disease 1
                olivopontocerebellar atrophy + 22
                plexopathy 0
                pontocerebellar hypoplasia + 32
                postpoliomyelitis syndrome 0
                primary cerebellar degeneration + 610
                prion disease + 108
                secondary Parkinson disease + 18
                stress-induced childhood-onset neurodegeneration with variable ataxia and seizures 1
                synucleinopathy + 403
                tauopathy + 506
    paths to the root