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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:childhood acute myeloid leukemia
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Accession:DOID:0070323 term browser browse the term
Definition:A childhood leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells. (DO)
Synonyms:exact_synonym: childhood acute myeloid leukaemia;   paediatric acute myeloid leukaemia;   pediatric acute myeloid leukemia
 narrow_synonym: childhood acute myeloid leukemia with maturation
 xref: EFO:0000330;   EFO:1001945;   ICD-O:M9861/3;   NCI:C9160


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childhood acute myeloid leukemia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ier2 immediate early response 2 ISO mRNA:increased expression:bone marrow (human) RGD PMID:34702297 RGD:153323323 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18976
    disease of cellular proliferation 7746
      Neoplasms by Histologic Type 5353
        leukemia 625
          childhood leukemia 1
            childhood acute myeloid leukemia 1
Path 2
Term Annotations click to browse term
  disease 18976
    disease of anatomical entity 18260
      Hemic and Lymphatic Diseases 3852
        hematopoietic system disease 3341
          Hematologic Neoplasms 1050
            hematologic cancer 1050
              leukemia 625
                myeloid leukemia 417
                  acute myeloid leukemia 345
                    childhood acute myeloid leukemia 1
paths to the root