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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fluoxymesterone
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Accession:CHEBI:5120 term browser browse the term
Definition:An anabolic androgenic steroid that has formula C20H29FO3.
Synonyms:exact_synonym: 9-fluoro-11beta,17beta-dihydroxy-17alpha-methylandrost-4-en-3-one
 related_synonym: 11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one;   17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone;   9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one;   9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone;   Formula=C20H29FO3;   InChI=1S/C20H29FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h10,14-16,23-24H,4-9,11H2,1-3H3/t14-,15-,16-,17-,18-,19-,20-/m0/s1;   InChIKey=YLRFCQOZQXIBAB-RBZZARIASA-N;   SMILES=[H][C@]1(O)C[C@@]2(C)[C@@]([H])(CC[C@]2(C)O)[C@]2([H])CCC3=CC(=O)CC[C@]3(C)[C@@]12F;   Testosterone, 9-fluoro-11beta-hydroxy-17-methyl-;   fluoximesterona;   fluoxymesteronum
 xref: Beilstein:2008796;   CAS:76-43-7;   DrugBank:DB01185;   Drug_Central:1210;   KEGG:D00327;   LIPID_MAPS_instance:LMST02020025
 xref_mesh: MESH:D005474
 xref: Patent:US2813881;   Wikipedia:Fluoxymesterone



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fluoxymesterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
decreases activity
ISO Fluoxymesterone inhibits the reaction [HSD11B2 protein results in decreased activity of Glucocorticoids]; HSD11B2 protein binds to and results in increased metabolism of Fluoxymesterone
Fluoxymesterone results in decreased activity of HSD11B2 protein
CTD PMID:22273746 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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Term Annotations click to browse term
  CHEBI ontology 19730
    role 19703
      application 19534
        pharmaceutical 19410
          drug 19410
            antineoplastic agent 17616
              fluoxymesterone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19730
    subatomic particle 19728
      composite particle 19728
        hadron 19728
          baryon 19728
            nucleon 19728
              atomic nucleus 19728
                atom 19728
                  main group element atom 19676
                    p-block element atom 19676
                      carbon group element atom 19620
                        carbon atom 19616
                          organic molecular entity 19616
                            organic group 18827
                              organic divalent group 18812
                                organodiyl group 18812
                                  carbonyl group 18778
                                    carbonyl compound 18778
                                      ketone 17093
                                        oxo steroid 10316
                                          3-oxo steroid 9919
                                            3-oxo-Delta(4) steroid 9156
                                              fluoxymesterone 1
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