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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fluoxymesterone
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Accession:CHEBI:5120 term browser browse the term
Definition:An anabolic androgenic steroid that has formula C20H29FO3.
Synonyms:exact_synonym: 9-fluoro-11beta,17beta-dihydroxy-17alpha-methylandrost-4-en-3-one
 related_synonym: 11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one;   17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone;   9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one;   9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone;   Formula=C20H29FO3;   InChI=1S/C20H29FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h10,14-16,23-24H,4-9,11H2,1-3H3/t14-,15-,16-,17-,18-,19-,20-/m0/s1;   InChIKey=YLRFCQOZQXIBAB-RBZZARIASA-N;   SMILES=[H][C@]1(O)C[C@@]2(C)[C@@]([H])(CC[C@]2(C)O)[C@]2([H])CCC3=CC(=O)CC[C@]3(C)[C@@]12F;   Testosterone, 9-fluoro-11beta-hydroxy-17-methyl-;   fluoximesterona;   fluoxymesteronum
 xref: Beilstein:2008796;   CAS:76-43-7;   DrugBank:DB01185;   Drug_Central:1210;   KEGG:D00327;   LIPID_MAPS_instance:LMST02020025
 xref_mesh: MESH:D005474
 xref: Patent:US2813881;   Wikipedia:Fluoxymesterone



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fluoxymesterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
decreases activity
ISO Fluoxymesterone inhibits the reaction [HSD11B2 protein results in decreased activity of Glucocorticoids]; HSD11B2 protein binds to and results in increased metabolism of Fluoxymesterone
Fluoxymesterone results in decreased activity of HSD11B2 protein
CTD PMID:22273746 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      application 19486
        pharmaceutical 19335
          drug 19335
            antineoplastic agent 17378
              fluoxymesterone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            organic group 18739
                              organic divalent group 18730
                                organodiyl group 18730
                                  carbonyl group 18678
                                    carbonyl compound 18678
                                      ketone 16926
                                        oxo steroid 9722
                                          3-oxo steroid 9280
                                            3-oxo-Delta(4) steroid 8423
                                              fluoxymesterone 1
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