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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dGTP
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Accession:CHEBI:16497 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside 5'-triphosphate having guanine as the nucleobase.
Synonyms:exact_synonym: 2'-deoxyguanosine 5'-(tetrahydrogen triphosphate)
 related_synonym: 2'-deoxy-GTP;   2'-deoxyguanosine 5'-triphosphate;   2'-deoxyguanosine triphosphate;   Deoxyguanosine 5'-triphosphate;   Deoxyguanosine triphosphate;   Formula=C10H16N5O13P3;   InChI=1S/C10H16N5O13P3/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1;   InChIKey=HAAZLUGHYHWQIW-KVQBGUIXSA-N;   SMILES=NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)N1;   deoxy-GTP
 alt_id: CHEBI:10497;   CHEBI:14076;   CHEBI:19247
 xref: CAS:2564-35-4;   Chemspider:58613;   DrugBank:DB02181;   ECMDB:ECMDB01440;   FooDB:FDB022623;   HMDB:HMDB0001440;   KEGG:C00286;   KNApSAcK:C00019346
 xref_mesh: MESH:C029603
 xref: PDBeChem:DGT;   PMID:11096070;   PMID:15708794;   PMID:17354649;   PMID:22844265;   PMID:24141705;   PMID:28373271;   PMID:31019074;   PMID:32402273;   PMID:33405358;   PMID:6783298;   PMID:7929110;   Reaxys:73481;   Wikipedia:Deoxyguanosine_triphosphate;   YMDB:YMDB00744
 cyclic_relationship: is_conjugate_acid_of CHEBI:57794


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dGTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 decreases abundance ISO SAMHD1 protein results in decreased abundance of deoxyguanosine triphosphate CTD PMID:26342080 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19810
      biological role 19808
        biochemical role 19543
          metabolite 19506
            eukaryotic metabolite 19330
              plant metabolite 17968
                dGTP 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19782
                    p-block element atom 19782
                      chalcogen 19533
                        oxygen atom 19530
                          oxygen molecular entity 19506
                            hydroxides 19312
                              oxoacid 18748
                                pnictogen oxoacid 14885
                                  phosphorus oxoacid 14476
                                    phosphoric acids 13916
                                      phosphoric acid 13916
                                        phosphoric acid derivative 13822
                                          phosphate 13821
                                            organic phosphate 13821
                                              carbohydrate phosphate 1860
                                                phospho sugar 1706
                                                  aldose phosphate 1703
                                                    aldopentose phosphate 1695
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-triphosphate 3
                                                                purine 2'-deoxyribonucleoside 5'-triphosphate 1
                                                                  dGTP 1
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