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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dGTP
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Accession:CHEBI:16497 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside 5'-triphosphate having guanine as the nucleobase.
Synonyms:exact_synonym: 2'-deoxyguanosine 5'-(tetrahydrogen triphosphate)
 related_synonym: 2'-deoxy-GTP;   2'-deoxyguanosine 5'-triphosphate;   2'-deoxyguanosine triphosphate;   Deoxyguanosine 5'-triphosphate;   Deoxyguanosine triphosphate;   Formula=C10H16N5O13P3;   InChI=1S/C10H16N5O13P3/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1;   InChIKey=HAAZLUGHYHWQIW-KVQBGUIXSA-N;   SMILES=NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)N1;   deoxy-GTP
 alt_id: CHEBI:10497;   CHEBI:14076;   CHEBI:19247
 xref: CAS:2564-35-4;   Chemspider:58613;   DrugBank:DB02181;   ECMDB:ECMDB01440;   FooDB:FDB022623;   HMDB:HMDB0001440;   KEGG:C00286;   KNApSAcK:C00019346
 xref_mesh: MESH:C029603
 xref: PDBeChem:DGT;   PMID:11096070;   PMID:15708794;   PMID:17354649;   PMID:22844265;   PMID:24141705;   PMID:28373271;   PMID:31019074;   PMID:32402273;   PMID:33405358;   PMID:6783298;   PMID:7929110;   Reaxys:73481;   Wikipedia:Deoxyguanosine_triphosphate;   YMDB:YMDB00744
 cyclic_relationship: is_conjugate_acid_of CHEBI:57794


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dGTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 decreases abundance ISO SAMHD1 protein results in decreased abundance of deoxyguanosine triphosphate CTD PMID:26342080 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19751
    role 19724
      biological role 19722
        biochemical role 19443
          metabolite 19430
            eukaryotic metabolite 19227
              plant metabolite 17860
                dGTP 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19751
    subatomic particle 19749
      composite particle 19749
        hadron 19749
          baryon 19749
            nucleon 19749
              atomic nucleus 19749
                atom 19749
                  main group element atom 19698
                    p-block element atom 19698
                      chalcogen 19492
                        oxygen atom 19469
                          oxygen molecular entity 19469
                            hydroxides 19267
                              oxoacid 18632
                                pnictogen oxoacid 11787
                                  phosphorus oxoacid 10769
                                    phosphoric acids 9753
                                      phosphoric acid 9753
                                        phosphoric acid derivative 9497
                                          phosphate 9495
                                            organic phosphate 9495
                                              carbohydrate phosphate 1837
                                                phospho sugar 1684
                                                  aldose phosphate 1682
                                                    aldopentose phosphate 1674
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-triphosphate 3
                                                                purine 2'-deoxyribonucleoside 5'-triphosphate 1
                                                                  dGTP 1
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