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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:trimethaphan
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Accession:CHEBI:9728 term browser browse the term
Definition:A complex heterocyclic sulfonium compound with an imidazolium core, used to treat hypertension.
Synonyms:exact_synonym: 1,3-dibenzyl-2-oxodecahydrothieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium
 related_synonym: Formula=C22H25N2OS;   InChI=1S/C22H25N2OS/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18/h1-6,8-11,19-21H,7,12-16H2/q+1;   InChIKey=CHQOEHPMXSHGCL-UHFFFAOYSA-N;   SMILES=O=C1N(Cc2ccccc2)C2C[S+]3CCCC3C2N1Cc1ccccc1;   Trimetaphan;   Trimetaphanum
 xref: CAS:7187-66-8;   DrugBank:DB01116;   Drug_Central:2752;   KEGG:C07174
 xref_mesh: MESH:D014294


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trimethaphan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPN sialophorin decreases response to substance ISO SPN protein results in decreased susceptibility to Trimethaphan CTD PMID:18711009 NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26050
    role 25966
      application 25188
        pharmaceutical 24562
          adjuvant 4821
            anaesthesia adjuvant 218
              trimethaphan 1
                trimethaphan camsylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26050
    subatomic particle 26025
      composite particle 26025
        hadron 26025
          baryon 26025
            nucleon 26025
              atomic nucleus 26025
                atom 26025
                  main group element atom 25850
                    p-block element atom 25850
                      p-block molecular entity 25845
                        chalcogen molecular entity 24932
                          sulfur molecular entity 20138
                            sulfonium compound 96
                              trimethaphan 1
                                trimethaphan camsylate 0
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