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spirotetramat - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:spirotetramat
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Accession:CHEBI:81975 term browser browse the term
Definition:An azaspiro compound that is methoxycyclohexane which is fused at position 4 to the 5-position of a 1,5-dihydro-2H-pyrrol-2-one that is substituted at positions 3 and 4 by 2,5-dimethylphenyl and (ethoxycarbonyl)oxy groups, respectively (the cis isomer). It is a proinsecticide (via hydrolysis of the ethyl carbonate group to give the corresponding 4-hydroxypyrrol-2-one, 'spirotetramat-enol') and is used for the control of a wide range of sucking insects on fruit and potato crops.
Synonyms:exact_synonym: (5s,8s)-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate
 related_synonym: Formula=C21H27NO5;   InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)/t15-,21+;   InChIKey=CLSVJBIHYWPGQY-GGYDESQDSA-N;   Movento;   SMILES=C1(=C(C=CC(=C1)C)C)C=2C(NC3(C2OC(OCC)=O)CCC(CC3)OC)=O;   Ultor;   cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethyl carbonate;   cis-3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl ethylcarbonate;   ethyl cis-8-methoxy-2-oxo-3-(2,5-xylyl)-1-azaspiro[4.5]dec-3-en-4-yl carbonate
 xref: CAS:203313-25-1;   KEGG:C18807
 xref_mesh: MESH:C570705
 xref: PMID:22160136;   PMID:22531003;   PMID:22872376;   PMID:24772560;   PMID:24835551;   PMID:25281882;   PMID:26081578;   PMID:26304426;   PMID:26383737;   PMID:26449612;   PMID:26743711;   PMID:26898726;   PMID:27083908;   PMID:27788413;   PMID:27857899;   PMID:27917277;   PMID:27989834;   PMID:28139069;   PMID:28334236;   PPDB:1119;   Patent:EP2039248;   Pesticides:spirotetramat;   Reaxys:14441154


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spirotetramat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxo1 forkhead box O1 increases expression ISO spirotetramat results in increased expression of FOXO1 mRNA CTD PMID:27917277 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:136,312,168...136,387,790
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G Vnn1 vanin 1 decreases expression ISO spirotetramat results in decreased expression of VNN1 mRNA CTD PMID:27917277 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:21,537,094...21,547,395
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      application 19697
        agrochemical 16869
          spirotetramat 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            heteroorganic entity 19521
                              organochalcogen compound 19282
                                organooxygen compound 19197
                                  carbon oxoacid 18676
                                    carboxylic acid 18673
                                      carboacyl group 17700
                                        univalent carboacyl group 17700
                                          carbamoyl group 17545
                                            carboxamide 17545
                                              lactam 8392
                                                gamma-lactam 6657
                                                  spirotetramat 2
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