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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:vilanterol
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Accession:CHEBI:75037 term browser browse the term
Definition:An dichlorobenzene derivative that is used in the form of its trifenate salt for treatment of chronic obstructive pulmonary disease.
Synonyms:exact_synonym: 4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
 related_synonym: Formula=C24H33Cl2NO5;   GW-642444x;   GW642444x;   InChI=1S/C24H33Cl2NO5/c25-21-6-5-7-22(26)20(21)17-32-13-12-31-11-4-2-1-3-10-27-15-24(30)18-8-9-23(29)19(14-18)16-28/h5-9,14,24,27-30H,1-4,10-13,15-17H2/t24-/m0/s1;   InChIKey=DAFYYTQWSAWIGS-DEOSSOPVSA-N;   SMILES=OCc1cc(ccc1O)[C@@H](O)CNCCCCCCOCCOCc1c(Cl)cccc1Cl;   vilanterolum
 xref: CAS:503068-34-6;   Drug_Central:4799;   KEGG:D09696
 xref_mesh: MESH:C550468
 xref: PMID:22241764;   PMID:22955035;   PMID:23043183;   PMID:23284643;   PMID:23348973;   PMID:23569370;   PMID:23830094;   Reaxys:11820500;   Wikipedia:Vilanterol
 cyclic_relationship: is_conjugate_base_of CHEBI:75039


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vilanterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 increases activity ISO vilanterol results in increased activity of ADRB2 protein CTD PMID:34601065 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      application 19661
        pharmaceutical 19502
          drug 19502
            bronchodilator agent 3820
              vilanterol 1
                Anoro Ellipta 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                carbocyclic compound 18588
                                  benzenoid aromatic compound 18000
                                    benzenes 17862
                                      chlorobenzenes 14839
                                        dichlorobenzene 11537
                                          vilanterol 1
                                            Anoro Ellipta 0
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