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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:P(1),P(6)-bis(5'-adenosyl)hexaphosphate
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Accession:CHEBI:63689 term browser browse the term
Definition:A diadenosyl hexaphosphate in which the two adenosin-5'-yl groups are attached at the P(1) and P(6) positions.
Synonyms:related_synonym: AP6A;   Adenosine 5'-hexaphosphate 5'-ester with adenosine;   Adenosine-(5')-hexaphospho-(5')-adenosine;   Ap(6)A;   AppppppA;   Diadenosine 5',5''''-P1,P6-hexaphosphate;   Diadenosine hexaphosphate;   Formula=C20H30N10O25P6;   InChI=1S/C20H30N10O25P6/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(49-19)1-47-56(35,36)51-58(39,40)53-60(43,44)55-61(45,46)54-59(41,42)52-57(37,38)48-2-8-12(32)14(34)20(50-8)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H,43,44)(H,45,46)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1;   InChIKey=PZCFFCOJNXGTIM-XPWFQUROSA-N;   P1,P6-di(Adenosine-5')hexaphosphate;   SMILES=Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O
 xref: CAS:56983-23-4;   HMDB:HMDB0001282
 xref_mesh: MESH:C070070
 xref: PDBeChem:B6P;   PMID:10385004;   PMID:10419486;   PMID:10523376;   PMID:11327631;   PMID:12121577;   PMID:14502438;   PMID:15066958;   PMID:1632493;   PMID:17824959;   PMID:20190246;   PMID:20807533;   PMID:7769127;   PMID:8114917;   PMID:8566144;   Reaxys:5230931
 cyclic_relationship: is_conjugate_acid_of CHEBI:63740


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P(1),P(6)-bis(5'-adenosyl)hexaphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt11 nudix hydrolase 11 multiple interactions
increases metabolic processing		 ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of adenosine 5'-pentaphosphate; [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:16,326,775...16,333,396
Ensembl chr  X:16,326,598...16,333,145 		JBrowse link
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  CHEBI ontology 19901
    role 19871
      application 19716
        pharmaceutical 19552
          drug 19552
            cardiovascular drug 8652
              vasoconstrictor agent 2041
                P(1),P(6)-bis(5'-adenosyl)hexaphosphate 1
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Term Annotations click to browse term
  CHEBI ontology 19901
    subatomic particle 19899
      composite particle 19899
        hadron 19899
          baryon 19899
            nucleon 19899
              atomic nucleus 19899
                atom 19899
                  main group element atom 19838
                    p-block element atom 19838
                      carbon group element atom 19778
                        carbon atom 19775
                          organic molecular entity 19775
                            heteroorganic entity 19534
                              organochalcogen compound 19295
                                organooxygen compound 19211
                                  carbohydrates and carbohydrate derivatives 15303
                                    carbohydrate 15303
                                      carbohydrate derivative 14317
                                        glycosyl compound 13082
                                          N-glycosyl compound 5877
                                            nucleoside 5736
                                              ribonucleoside 1155
                                                purine ribonucleoside 823
                                                  purines D-ribonucleoside 420
                                                    adenosine 407
                                                      diadenosyl hexaphosphate 1
                                                        P(1),P(6)-bis(5'-adenosyl)hexaphosphate 1
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