.
P(1),P(6)-bis(5'-adenosyl)hexaphosphate - Ontology Report - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:P(1),P(6)-bis(5'-adenosyl)hexaphosphate
go back to main search page
Accession:CHEBI:63689 term browser browse the term
Definition:A diadenosyl hexaphosphate in which the two adenosin-5'-yl groups are attached at the P(1) and P(6) positions.
Synonyms:related_synonym: AP6A;   Adenosine 5'-hexaphosphate 5'-ester with adenosine;   Adenosine-(5')-hexaphospho-(5')-adenosine;   Ap(6)A;   AppppppA;   Diadenosine 5',5''''-P1,P6-hexaphosphate;   Diadenosine hexaphosphate;   Formula=C20H30N10O25P6;   InChI=1S/C20H30N10O25P6/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(49-19)1-47-56(35,36)51-58(39,40)53-60(43,44)55-61(45,46)54-59(41,42)52-57(37,38)48-2-8-12(32)14(34)20(50-8)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H,43,44)(H,45,46)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1;   InChIKey=PZCFFCOJNXGTIM-XPWFQUROSA-N;   P1,P6-di(Adenosine-5')hexaphosphate;   SMILES=Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O
 xref: CAS:56983-23-4;   HMDB:HMDB0001282
 xref_mesh: MESH:C070070
 xref: PDBeChem:B6P;   PMID:10385004;   PMID:10419486;   PMID:10523376;   PMID:11327631;   PMID:12121577;   PMID:14502438;   PMID:15066958;   PMID:1632493;   PMID:17824959;   PMID:20190246;   PMID:20807533;   PMID:7769127;   PMID:8114917;   PMID:8566144;   Reaxys:5230931
 cyclic_relationship: is_conjugate_acid_of CHEBI:63740


 Loading Annotations... 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
X

show annotations for term's descendants           Sort by:
P(1),P(6)-bis(5'-adenosyl)hexaphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt11 nudix hydrolase 11 multiple interactions
increases metabolic processing
ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of adenosine 5'-pentaphosphate; [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:18,998,587...19,005,208
Ensembl chr  X:16,326,598...16,333,145
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      application 20617
        pharmaceutical 20413
          drug 20413
            cardiovascular drug 8992
              vasoconstrictor agent 2054
                P(1),P(6)-bis(5'-adenosyl)hexaphosphate 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      carbon group element atom 20710
                        carbon atom 20704
                          organic molecular entity 20704
                            heteroorganic entity 20215
                              organochalcogen compound 19902
                                organooxygen compound 19804
                                  carbohydrates and carbohydrate derivatives 15436
                                    carbohydrate 15436
                                      carbohydrate derivative 14453
                                        glycosyl compound 13161
                                          N-glycosyl compound 5900
                                            nucleoside 5753
                                              ribonucleoside 1160
                                                purine ribonucleoside 828
                                                  purines D-ribonucleoside 427
                                                    adenosine 414
                                                      diadenosyl hexaphosphate 1
                                                        P(1),P(6)-bis(5'-adenosyl)hexaphosphate 1
paths to the root