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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-chlorouracil
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Accession:CHEBI:60762 term browser browse the term
Definition:An organochlorine compound consisting of uracil having an chloro substituent at the 5-position.
Synonyms:exact_synonym: 5-chloropyrimidine-2,4(1H,3H)-dione
 related_synonym: Formula=C4H3ClN2O2;   InChI=1S/C4H3ClN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9);   InChIKey=ZFTBZKVVGZNMJR-UHFFFAOYSA-N;   SMILES=Clc1c[nH]c(=O)[nH]c1=O
 xref: CAS:1820-81-1
 xref_mesh: MESH:C010889
 xref: PMID:10513989;   PMID:3007759;   PMID:3950402;   Reaxys:127173


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5-chlorouracil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta affects metabolic processing ISO POLB protein affects the metabolism of 5-chlorouracil CTD PMID:20104909 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Smug1 single-strand-selective monofunctional uracil-DNA glycosylase 1 affects metabolic processing ISO SMUG1 protein affects the metabolism of 5-chlorouracil CTD PMID:20104909 NCBI chr 7:134,288,565...134,302,179
Ensembl chr 7:134,287,675...134,297,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19904
    role 19875
      application 19718
        pro-agent 11570
          prodrug 11314
            uracil 8033
              5-chlorouracil 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19904
    subatomic particle 19902
      composite particle 19902
        hadron 19902
          baryon 19902
            nucleon 19902
              atomic nucleus 19902
                atom 19902
                  main group element atom 19841
                    p-block element atom 19841
                      carbon group element atom 19779
                        carbon atom 19776
                          organic molecular entity 19776
                            organic molecule 19730
                              organic cyclic compound 19522
                                organic heterocyclic compound 18896
                                  organic heteromonocyclic compound 17825
                                    diazines 13238
                                      pyrimidines 13108
                                        pyrimidine nucleobase 8579
                                          uracil 8033
                                            5-chlorouracil 2
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