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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dopachrome
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Accession:CHEBI:49108 term browser browse the term
Definition:An orthoquinone that has formula C9H7NO4.
Synonyms:related_synonym: 2,3,5,6-tetrahydro-5,6-dioxo-1H-indole-2-carboxylic acid;   Formula=C9H7NO4;   InChI=1S/C9H7NO4/c11-7-2-4-1-6(9(13)14)10-5(4)3-8(7)12/h2-3,6,10H,1H2,(H,13,14);   InChIKey=VJNCICVKUHKIIV-UHFFFAOYSA-N;   SMILES=OC(=O)C1CC2=CC(=O)C(=O)C=C2N1
 xref: Beilstein:181818;   CAS:3571-34-4
 xref_mesh: MESH:C001123
 xref: PMID:21706729
 cyclic_relationship: is_tautomer_of CHEBI:2003


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dopachrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pomc proopiomelanocortin multiple interactions ISO [POMC protein modified form results in increased activity of TYR protein] which results in increased chemical synthesis of dopachrome; Quercetin analog inhibits the reaction [[POMC protein modified form results in increased activity of TYR protein] which results in increased chemical synthesis of dopachrome] CTD PMID:26586997 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Tyr tyrosinase multiple interactions ISO [POMC protein modified form results in increased activity of TYR protein] which results in increased chemical synthesis of dopachrome; Quercetin analog inhibits the reaction [[POMC protein modified form results in increased activity of TYR protein] which results in increased chemical synthesis of dopachrome] CTD PMID:26586997 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19893
    chemical entity 19891
      group 19844
        inorganic group 19421
          oxo group 18923
            organic oxo compound 18923
              carbonyl compound 18923
                ketone 17271
                  cyclic ketone 15920
                    quinone 9908
                      orthoquinones 3274
                        dopachrome 2
                          D-dopachrome 0
                          L-dopachrome 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19893
    subatomic particle 19891
      composite particle 19891
        hadron 19891
          baryon 19891
            nucleon 19891
              atomic nucleus 19891
                atom 19891
                  main group element atom 19830
                    p-block element atom 19830
                      carbon group element atom 19771
                        carbon atom 19767
                          organic molecular entity 19767
                            heteroorganic entity 19525
                              organochalcogen compound 19286
                                organooxygen compound 19202
                                  carbonyl compound 18923
                                    ketone 17271
                                      cyclic ketone 15920
                                        quinone 9908
                                          orthoquinones 3274
                                            dopachrome 2
                                              D-dopachrome 0
                                              L-dopachrome 0
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