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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:atomoxetine hydrochloride
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Accession:CHEBI:331697 term browser browse the term
Definition:The hydrochloride salt of atomoxetine.
Synonyms:exact_synonym: (3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine hydrochloride
 related_synonym: (-)-N-Methyl-3-phenyl-3-(o-tolyloxy)propylamine hydrochloride;   (R)-Tomoxetine hydrochloride;   Atomoxetine HCl;   Formula=C17H22ClNO;   InChI=1S/C17H21NO.ClH/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15;/h3-11,17-18H,12-13H2,1-2H3;1H/t17-;/m1./s1;   InChIKey=LUCXVPAZUDVVBT-UNTBIKODSA-N;   SMILES=Cl.CNCC[C@@H](Oc1ccccc1C)c1ccccc1;   Tomoxetine hydrochloride;   atomoxetine;   tomoxetine
 xref: Beilstein:5318974;   CAS:82248-59-7;   DrugBank:DB00289;   KEGG:D02574
 xref_mesh: MESH:D000069445


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atomoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases hydroxylation
increases metabolic processing
multiple interactions		 ISO CYP2D6 protein results in increased hydroxylation of Atomoxetine Hydrochloride
CYP2D6 protein results in increased metabolism of Atomoxetine Hydrochloride
Quinidine inhibits the reaction [CYP2D6 protein results in increased metabolism of Atomoxetine Hydrochloride]		 CTD PMID:17470523 PMID:34431675 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      biological role 19858
        xenobiotic 18739
          atomoxetine 1
            atomoxetine hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    main group molecular entity 19806
                      s-block molecular entity 19641
                        hydrogen molecular entity 19622
                          hydrides 19150
                            inorganic hydride 18152
                              pnictogen hydride 18164
                                nitrogen hydride 18055
                                  azane 17882
                                    ammonia 17860
                                      organic amino compound 17860
                                        secondary amino compound 6962
                                          atomoxetine 1
                                            atomoxetine hydrochloride 1
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