.
gramine - Ontology Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gramine
go back to main search page
Accession:CHEBI:28948 term browser browse the term
Definition:An aminoalkylindole that is indole carrying a dimethylaminomethyl substituent at postion 3.
Synonyms:exact_synonym: 1-(1H-indol-3-yl)-N,N-dimethylmethanamine
 related_synonym: (1H-indol-3-ylmethyl)dimethylamine;   3-(Dimethylaminomethyl)indole;   3-(N,N-Dimethylaminomethyl)indole;   3-[(Dimethylamino)methyl]indole;   Donaxin;   Donaxine;   Formula=C11H14N2;   Gramin;   InChI=1S/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H3;   InChIKey=OCDGBSUVYYVKQZ-UHFFFAOYSA-N;   Indol-3-ylmethyldimethylamine;   N,N-Dimethyl-1H-indole-3-methanamine;   SMILES=C1(=CNC2=C1C=CC=C2)CN(C)C;   beta-Dimethylaminomethylindole
 alt_id: CHEBI:24428;   CHEBI:5531
 xref: CAS:87-52-5;   HMDB:HMDB0035762;   KEGG:C08304;   KNApSAcK:C00001411;   LINCS:LSM-6572
 xref_mesh: MESH:C007884
 xref: MetaCyc:CPD-8915;   PMID:23700450;   PMID:24332729;   PMID:24979400;   PMID:25149234;   PMID:25281166;   PMID:26920698;   PMID:27037659;   PMID:27138201;   PMID:27157767;   PMID:27250087;   PMID:27280380;   PMID:27854190;   PMID:28004092;   Reaxys:140521
 cyclic_relationship: is_conjugate_base_of CHEBI:136516

1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
X

show annotations for term's descendants           Sort by:
gramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 multiple interactions ISO gramine binds to and results in increased activity of ADIPOR1 protein CTD PMID:23691032 NCBI chr13:48,411,438...48,431,251
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases phosphorylation ISO gramine results in decreased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO gramine results in increased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases phosphorylation ISO gramine results in increased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      biological role 19856
        antimicrobial agent 18257
          antiviral agent 11392
            gramine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            organic molecule 19713
                              organic cyclic compound 19505
                                organic heterocyclic compound 18875
                                  organic heteropolycyclic compound 18302
                                    organic heterobicyclic compound 17242
                                      benzopyrrole 9750
                                        indoles 9440
                                          aminoalkylindole 587
                                            gramine 4
paths to the root