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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:taurocholic acid
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Accession:CHEBI:28865 term browser browse the term
Definition:A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
Synonyms:exact_synonym: 2-[(3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholan-24-yl)amino]ethanesulfonic acid
 related_synonym: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanic acid 24-taurine;   Choloyl-taurine;   Cholyltaurine;   Formula=C26H45NO7S;   InChI=1S/C26H45NO7S/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34)/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-/m1/s1;   InChIKey=WBWWGRHZICKQGZ-HZAMXZRMSA-N;   N-choloyltaurine;   SMILES=[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]1([H])C[C@H](O)[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS(O)(=O)=O;   Taurocholate;   cholic acid taurine conjugate
 alt_id: CHEBI:26854;   CHEBI:3672;   CHEBI:45901;   CHEBI:9408
 xref: Beilstein:2956951;   CAS:81-24-3;   DrugBank:DB04348;   HMDB:HMDB0000036;   KEGG:C02258;   KEGG:C05122;   LINCS:LSM-5866;   LIPID_MAPS_instance:LMST05040001
 xref_mesh: MESH:D013656
 xref: PDBeChem:TCH;   PMID:11160372;   PMID:24412572;   PMID:24551170;   Reaxys:2956951;   Wikipedia:Taurocholic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:36257


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taurocholic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLCO1B2 solute carrier organic anion transporter family member 1B2 increases transport EXP SLCO1B3 protein results in increased transport of Taurocholic Acid CTD PMID:20079461 NCBI chr27:26,411,008...26,496,174
Ensembl chr27:26,411,010...26,470,989 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 501
    role 501
      chemical role 426
        antioxidant 44
          taurine 1
            bile acid taurine conjugate 1
              taurocholic acid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 501
    subatomic particle 501
      composite particle 501
        hadron 501
          baryon 501
            nucleon 501
              atomic nucleus 501
                atom 501
                  main group element atom 494
                    p-block element atom 494
                      carbon group element atom 483
                        carbon atom 482
                          organic molecular entity 482
                            organic molecule 473
                              organic cyclic compound 456
                                organic polycyclic compound 65
                                  steroid 40
                                    steroid fundamental parent 20
                                      cholane 2
                                        cholanoid 2
                                          cholanic acids 2
                                            cholanic acid 2
                                              5beta-cholanic acid 2
                                                hydroxy-5beta-cholanic acid 2
                                                  trihydroxy-5beta-cholanic acid 1
                                                    cholic acid 1
                                                      taurocholic acid 1
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