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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:nucleocidin
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Accession:CHEBI:166872 term browser browse the term
Definition:A nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness.
Synonyms:exact_synonym: [(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-fluoro-3,4-dihydroxyoxolan-2-yl]methyl sulfamate
 related_synonym: 4'-C-fluoroadenosine 5'-sulfamate;   4'-fluoro-5'-O-sulfamoyladenosine;   4'-fluoro-5'-O-sulphamoyladenosine;   Formula=C10H13FN6O6S;   InChI=1S/C10H13FN6O6S/c11-10(1-22-24(13,20)21)6(19)5(18)9(23-10)17-3-16-4-7(12)14-2-15-8(4)17/h2-3,5-6,9,18-19H,1H2,(H2,12,14,15)(H2,13,20,21)/t5-,6+,9-,10-/m1/s1;   InChIKey=LTBCQBSAWAZBDF-MLTZYSBQSA-N;   SMILES=NC1=C2N=CN([C@@H]3O[C@](F)(COS(N)(=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1;   T-3018;   [(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-fluoro-3,4-dihydroxytetrahydrofuran-2-yl]methyl sulfamate;   [(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-2-fluoro-3,4-dihydroxyoxolan-2-yl]methyl sulfamate;   antibiotic T-3018
 xref: CAS:24751-69-7;   Chemspider:65250;   MetaCyc:CPD-12712;   PMID:1085509;   PMID:1262649;   PMID:13425454;   PMID:13425455;   PMID:13439466;   PMID:13834368;   PMID:24544578;   PMID:26374477;   PMID:27845468;   PMID:28920128;   PMID:30641108;   PMID:32110306;   PMID:5131149;   PMID:5776261;   PMID:5933868;   Wikipedia:Nucleocidin


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Term Annotations click to browse term
  CHEBI ontology 19893
    role 19863
      biological role 19861
        antimicrobial agent 18261
          nucleoside antibiotic 347
            nucleocidin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19893
    subatomic particle 19891
      composite particle 19891
        hadron 19891
          baryon 19891
            nucleon 19891
              atomic nucleus 19891
                atom 19891
                  main group element atom 19830
                    p-block element atom 19830
                      carbon group element atom 19771
                        carbon atom 19767
                          organic molecular entity 19767
                            heteroorganic entity 19525
                              organochalcogen compound 19286
                                organooxygen compound 19202
                                  carbohydrates and carbohydrate derivatives 15304
                                    carbohydrate 15304
                                      carbohydrate derivative 14320
                                        glycosyl compound 13082
                                          N-glycosyl compound 5879
                                            nucleoside 5737
                                              ribonucleoside 1154
                                                purine ribonucleoside 822
                                                  purines D-ribonucleoside 420
                                                    adenosine 407
                                                      nucleocidin 0
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