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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dCTP
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Accession:CHEBI:16311 term browser browse the term
Definition:A 2'-deoxycytidine phosphate having cytosine as the nucleobase.
Synonyms:exact_synonym: 2'-deoxycytidine 5'-(tetrahydrogen triphosphate)
 related_synonym: 2'-Deoxycytidine 5'-triphosphate;   2'-deoxy-CTP;   2'-deoxycytidine triphosphate;   Deoxycytidine 5'-triphosphate;   Deoxycytidine triphosphate;   Formula=C9H16N3O13P3;   InChI=1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1;   InChIKey=RGWHQCVHVJXOKC-SHYZEUOFSA-N;   SMILES=NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1;   deoxy-CTP
 alt_id: CHEBI:10494;   CHEBI:14072;   CHEBI:19243;   CHEBI:41805
 xref: CAS:2056-98-6;   Chemspider:58601;   DrugBank:DB03258;   FooDB:FDB022359;   HMDB:HMDB0000998;   KEGG:C00458
 xref_mesh: MESH:C024107
 xref: PDBeChem:DCP;   PMID:11200258;   PMID:15787173;   PMID:15935150;   PMID:16061253;   PMID:16061997;   PMID:16120835;   PMID:19328748;   PMID:22212996;   PMID:29989586;   PMID:31377845;   PMID:32800127;   PMID:32926292;   PMID:34110794;   PMID:6601514;   PMID:761229;   PMID:7877593;   Wikipedia:Deoxycytidine_triphosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:57724


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dCTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dck deoxycytidine kinase increases metabolic processing
affects activity		 ISO DCK protein results in increased metabolism of 2'-deoxycytidine 5'-triphosphate
2'-deoxycytidine 5'-triphosphate affects the activity of DCK protein		 CTD PMID:9586059 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247 		JBrowse link
G Polk DNA polymerase kappa multiple interactions
affects binding		 ISO 2'-deoxycytidine 5'-triphosphate promotes the reaction [N(2)-furfuryl-deoxyguanosine results in increased stability of POLK protein]; N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone inhibits the reaction [POLK protein binds to 2'-deoxycytidine 5'-triphosphate] CTD PMID:28823149 PMID:31286773 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      biological role 19858
        biochemical role 19566
          metabolite 19533
            prokaryotic metabolite 18578
              bacterial metabolite 18578
                Escherichia coli metabolite 18510
                  dCTP 2
                    5-iododeoxycytidine triphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      chalcogen 19577
                        oxygen atom 19549
                          oxygen molecular entity 19529
                            hydroxides 19334
                              oxoacid 18791
                                pnictogen oxoacid 14973
                                  phosphorus oxoacid 14576
                                    phosphoric acids 13937
                                      phosphoric acid 13926
                                        phosphoric acid derivative 13847
                                          phosphate 13846
                                            organic phosphate 13835
                                              carbohydrate phosphate 1964
                                                phospho sugar 1809
                                                  aldose phosphate 1808
                                                    aldopentose phosphate 1798
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-triphosphate 3
                                                                pyrimidine 2'-deoxyribonucleoside 5'-triphosphate 2
                                                                  dCTP 2
                                                                    5-iododeoxycytidine triphosphate 0
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