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dCTP - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dCTP
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Accession:CHEBI:16311 term browser browse the term
Definition:A 2'-deoxycytidine phosphate having cytosine as the nucleobase.
Synonyms:exact_synonym: 2'-deoxycytidine 5'-(tetrahydrogen triphosphate)
 related_synonym: 2'-Deoxycytidine 5'-triphosphate;   2'-deoxy-CTP;   2'-deoxycytidine triphosphate;   Deoxycytidine 5'-triphosphate;   Deoxycytidine triphosphate;   Formula=C9H16N3O13P3;   InChI=1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1;   InChIKey=RGWHQCVHVJXOKC-SHYZEUOFSA-N;   SMILES=NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1;   deoxy-CTP
 alt_id: CHEBI:10494;   CHEBI:14072;   CHEBI:19243;   CHEBI:41805
 xref: CAS:2056-98-6;   Chemspider:58601;   DrugBank:DB03258;   FooDB:FDB022359;   HMDB:HMDB0000998;   KEGG:C00458
 xref_mesh: MESH:C024107
 xref: PDBeChem:DCP;   PMID:11200258;   PMID:15787173;   PMID:15935150;   PMID:16061253;   PMID:16061997;   PMID:16120835;   PMID:19328748;   PMID:22212996;   PMID:29989586;   PMID:31377845;   PMID:32800127;   PMID:32926292;   PMID:34110794;   PMID:6601514;   PMID:761229;   PMID:7877593;   Wikipedia:Deoxycytidine_triphosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:57724

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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dck deoxycytidine kinase increases metabolic processing
affects activity		 ISO DCK protein results in increased metabolism of 2'-deoxycytidine 5'-triphosphate
2'-deoxycytidine 5'-triphosphate affects the activity of DCK protein		 CTD PMID:9586059 NCBI chr14:19,589,298...19,610,326
Ensembl chr14:19,305,218...19,326,247 		JBrowse link
G Polk DNA polymerase kappa multiple interactions
affects binding		 ISO 2'-deoxycytidine 5'-triphosphate promotes the reaction [N(2)-furfuryl-deoxyguanosine results in increased stability of POLK protein]; N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone inhibits the reaction [POLK protein binds to 2'-deoxycytidine 5'-triphosphate] CTD PMID:28823149 PMID:31286773 NCBI chr 2:29,556,831...29,616,960
Ensembl chr 2:27,822,679...27,882,313 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      biological role 19856
        biochemical role 19566
          metabolite 19554
            prokaryotic metabolite 18592
              bacterial metabolite 18592
                Escherichia coli metabolite 18503
                  dCTP 2
                    5-iododeoxycytidine triphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      chalcogen 19580
                        oxygen atom 19551
                          oxygen molecular entity 19551
                            hydroxides 19361
                              oxoacid 18797
                                pnictogen oxoacid 15018
                                  phosphorus oxoacid 14577
                                    phosphoric acids 13927
                                      phosphoric acid 13927
                                        phosphoric acid derivative 13839
                                          phosphate 13838
                                            organic phosphate 13838
                                              carbohydrate phosphate 1969
                                                phospho sugar 1814
                                                  aldose phosphate 1811
                                                    aldopentose phosphate 1803
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-triphosphate 3
                                                                pyrimidine 2'-deoxyribonucleoside 5'-triphosphate 2
                                                                  dCTP 2
                                                                    5-iododeoxycytidine triphosphate 0
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