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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:6-[(5-hydroxypentyl)amino]-5-[(E)-(2-oxopropylidene)amino]uracil
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Accession:CHEBI:149728 term browser browse the term
Definition:A nucleobase analogue that is uracil substituted with a (5-hydroxypentyl)amino group at position 6 and an (E)-(2-oxopropylidene)amino group at position 5; one of 20 modifications to the potent microbial riboflavin-based metabolite antigen 5-(2-oxopropylideneamino)-6-D-ribityl aminouracil (5-OP-RU), an activator of mucosal-associated invariant T (MAIT) cells when presented by the MR1 protein (reported in MED:32123373).
Synonyms:exact_synonym: 6-[(5-hydroxypentyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione
 related_synonym: 5'-OH-pentyl-5-OP-U;   6-[(5-hydroxypentyl)amino]-5-[[(1E)-2-oxopropylidene]amino]-2,4(1H,3H)-pyrimidinedione;   Formula=C12H18N4O4;   InChI=1S/C12H18N4O4/c1-8(18)7-14-9-10(13-5-3-2-4-6-17)15-12(20)16-11(9)19/h7,17H,2-6H2,1H3,(H3,13,15,16,19,20)/b14-7+;   InChIKey=ZSHIZCPIXIPJJT-VGOFMYFVSA-N;   SMILES=C(CNC1=C(C(NC(N1)=O)=O)/N=C/C(=O)C)CCCO
 xref: PMID:32123373


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          6-[(5-hydroxypentyl)amino]-5-[(E)-(2-oxopropylidene)amino]uracil 0
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    subatomic particle 0
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          baryon 0
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                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            organic molecule 0
                              organic cyclic compound 0
                                organic heterocyclic compound 0
                                  organic heteromonocyclic compound 0
                                    diazines 0
                                      pyrimidines 0
                                        pyrimidine nucleobase 0
                                          uracil 0
                                            6-[(5-hydroxypentyl)amino]-5-[(E)-(2-oxopropylidene)amino]uracil 0
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