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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:12-hydroxynevirapine
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Accession:CHEBI:145206 term browser browse the term
Definition:A dipyridodiazepine that is nevirapine in which one of the hydrogens of the methyl group has been substituted by a hydroxy group. It is a metabolite of the anti-HIV drug, nevirapine.
Synonyms:exact_synonym: 11-cyclopropyl-4-(hydroxymethyl)-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
 related_synonym: 11-cyclopropyl-4-(hydroxymethyl)-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one;   12-OH-NVP;   12-hydroxy-NVP;   12-hydroxy-nevirapine;   Formula=C15H14N4O2;   InChI=1S/C15H14N4O2/c20-8-9-5-7-17-14-12(9)18-15(21)11-2-1-6-16-13(11)19(14)10-3-4-10/h1-2,5-7,10,20H,3-4,8H2,(H,18,21);   InChIKey=SEBABOMFNCVZGF-UHFFFAOYSA-N;   N(11)-cyclopropyl-4-hydroxymethyl-5,11-dihydro-6H-dipyrido(3,2-b:2,3-e)(1,4)diazepin-6-one;   SMILES=O=C1NC=2C(N(C3CC3)C=4N=CC=CC41)=NC=CC2CO
 xref: CAS:133627-24-4;   HMDB:HMDB0013911;   PMID:10421616;   PMID:17618842;   PMID:18042504;   PMID:18597499;   PMID:20392079;   PMID:23459477;   PMID:23590230;   PMID:23947594;   PMID:24051761;   PMID:25275777;   PMID:25394082;   PMID:26620700;   PMID:29309900;   PMID:30028994


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19893
      biological role 19891
        antimicrobial agent 18273
          antiviral agent 11338
            antiviral drug 1989
              nevirapine 177
                12-hydroxynevirapine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    p-block element atom 19865
                      carbon group element atom 19804
                        carbon atom 19801
                          organic molecular entity 19801
                            organic molecule 19754
                              organic cyclic compound 19544
                                organic heterocyclic compound 18909
                                  organic heteropolycyclic compound 18316
                                    organic heterotricyclic compound 15655
                                      dipyridodiazepine 177
                                        nevirapine 177
                                          12-hydroxynevirapine 0
paths to the root