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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dipyridodiazepine
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Accession:CHEBI:63667 term browser browse the term
Definition:An organic heterotricyclic compound whose skeleton consists of a diazepine ring which is fused to two pyridine rings.
Synonyms:related_synonym: dipyridodiazepines


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nevirapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP Nevirapine results in increased expression of ABCB1A mRNA CTD PMID:23947594 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 decreases expression EXP Nevirapine metabolite results in decreased expression of ADAMTS9 mRNA; Nevirapine results in decreased expression of ADAMTS9 mRNA CTD PMID:23947594 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 increases expression EXP Nevirapine metabolite results in increased expression of ADGRF5 mRNA CTD PMID:23947594 NCBI chr 9:20,091,121...20,195,706
Ensembl chr 9:20,091,099...20,195,566
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
increases secretion
ISO Nevirapine results in increased expression of ADIPOQ mRNA
Nevirapine results in increased secretion of ADIPOQ protein
CTD PMID:21619898 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP Nevirapine metabolite results in decreased expression of AIF1 mRNA CTD PMID:23947594 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Alb albumin affects binding ISO Nevirapine binds to ALB protein CTD PMID:15814459, PMID:16336266 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO Nevirapine results in increased expression of APOA1 protein CTD PMID:19667106 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Ar androgen receptor increases expression ISO Nevirapine results in increased expression of AR mRNA; Nevirapine results in increased expression of AR protein CTD PMID:19152342 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Armcx2 armadillo repeat containing, X-linked 2 decreases expression EXP Nevirapine metabolite results in decreased expression of ARMCX2 mRNA; Nevirapine results in decreased expression of ARMCX2 mRNA CTD PMID:23947594 NCBI chr  X:105,617,383...105,622,209
Ensembl chr  X:105,617,385...105,622,156
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression EXP Nevirapine metabolite results in increased expression of ARNT mRNA CTD PMID:23947594 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Cd36 CD36 molecule increases expression EXP Nevirapine metabolite results in increased expression of CD36 mRNA CTD PMID:23947594 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO Nevirapine results in increased expression of CEBPA mRNA CTD PMID:21619898 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP Nevirapine results in increased expression of CES2 mRNA CTD PMID:23947594 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression ISO Nevirapine results in increased expression of CIITA CTD PMID:26626330 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 decreases expression EXP Nevirapine results in decreased expression of CLEC4A1 mRNA CTD PMID:23947594 NCBI chr 4:155,913,366...155,923,079
Ensembl chr 4:155,913,366...155,923,079
JBrowse link
G Clec4m C-type lectin domain family 4 member M increases expression EXP Nevirapine metabolite results in increased expression of CD209B mRNA CTD PMID:23947594 NCBI chr12:2,817,633...2,826,303
Ensembl chr12:2,816,065...2,826,378
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression EXP Nevirapine results in decreased expression of COTL1 mRNA CTD PMID:23947594 NCBI chr19:52,465,074...52,499,433
Ensembl chr19:52,465,087...52,499,433
JBrowse link
G Cux2 cut-like homeobox 2 decreases expression EXP Nevirapine metabolite results in decreased expression of CUX2 mRNA CTD PMID:23947594 NCBI chr12:40,016,774...40,221,067
Ensembl chr12:40,018,937...40,219,291
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Nevirapine metabolite results in increased expression of CYP2B1 mRNA; Nevirapine results in increased expression of CYP2B1 mRNA CTD PMID:23947594 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Nevirapine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Nevirapine results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 affects binding EXP Nevirapine binds to CYP2C11 protein CTD PMID:22793666 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects binding
increases expression
EXP Nevirapine binds to CYP3A23-3A1 protein
Nevirapine results in increased expression of CYP3A23-3A1 mRNA
CTD PMID:22793666, PMID:23947594 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression EXP Nevirapine results in increased expression of CYP3A9 mRNA CTD PMID:23947594 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Nevirapine metabolite results in increased expression of CYP4B1 mRNA CTD PMID:23947594 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Dapk1 death associated protein kinase 1 increases expression EXP Nevirapine metabolite results in increased expression of DAPK1 mRNA CTD PMID:23947594 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression EXP Nevirapine metabolite results in decreased expression of DBP mRNA CTD PMID:23947594 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Ddhd1 DDHD domain containing 1 decreases expression EXP Nevirapine results in decreased expression of DDHD1 mRNA CTD PMID:23947594 NCBI chr15:19,963,639...20,032,263
Ensembl chr15:19,965,187...20,032,191
JBrowse link
G Dip2a disco-interacting protein 2 homolog A increases expression EXP Nevirapine results in increased expression of DIP2A mRNA CTD PMID:23947594 NCBI chr20:13,044,056...13,127,971
Ensembl chr20:13,044,104...13,127,487
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression EXP Nevirapine metabolite results in increased expression of DNAJB5 mRNA CTD PMID:23947594 NCBI chr 5:58,393,197...58,402,162
Ensembl chr 5:58,393,233...58,401,870
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression EXP Nevirapine results in increased expression of EDEM1 mRNA CTD PMID:23947594 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Egf epidermal growth factor decreases expression ISO Nevirapine results in decreased expression of EGF mRNA CTD PMID:19152342 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Nevirapine results in decreased expression of EGFR mRNA CTD PMID:19152342 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 decreases expression EXP Nevirapine results in decreased expression of EPB41L3 mRNA CTD PMID:23947594 NCBI chr 9:117,314,935...117,666,408
Ensembl chr 9:117,538,009...117,666,410
JBrowse link
G Esm1 endothelial cell-specific molecule 1 increases expression EXP Nevirapine metabolite results in increased expression of ESM1 mRNA; Nevirapine results in increased expression of ESM1 mRNA CTD PMID:23947594 NCBI chr 2:45,104,392...45,113,130
Ensembl chr 2:45,104,305...45,113,131
JBrowse link
G Fam107a family with sequence similarity 107, member A increases expression EXP Nevirapine results in increased expression of FAM107A mRNA CTD PMID:23947594 NCBI chr15:18,399,145...18,415,959
Ensembl chr15:18,399,515...18,415,965
JBrowse link
G Fibin fin bud initiation factor homolog increases expression EXP Nevirapine results in increased expression of FIBIN mRNA CTD PMID:23947594 NCBI chr 3:101,545,207...101,547,478
Ensembl chr 3:101,545,208...101,547,478
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression EXP Nevirapine metabolite results in increased expression of FKBP5 mRNA; Nevirapine results in increased expression of FKBP5 mRNA CTD PMID:23947594 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP Nevirapine metabolite results in decreased expression of FMO1 mRNA CTD PMID:23947594 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression EXP Nevirapine results in increased expression of GADD45B mRNA CTD PMID:23947594 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Nevirapine metabolite results in decreased expression of GLUL mRNA CTD PMID:23947594 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases glutathionylation ISO GSTA1 protein results in increased glutathionylation of Nevirapine metabolite CTD PMID:27989146 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases glutathionylation ISO GSTM1 protein results in increased glutathionylation of Nevirapine metabolite CTD PMID:27989146 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases glutathionylation ISO GSTP1 protein results in increased glutathionylation of Nevirapine metabolite CTD PMID:27989146 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gzma granzyme A decreases expression EXP Nevirapine metabolite results in decreased expression of GZMA mRNA CTD PMID:23947594 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Gzmf granzyme F decreases expression EXP Nevirapine metabolite results in decreased expression of GZMF mRNA CTD PMID:23947594 NCBI chr15:35,182,405...35,195,725
Ensembl chr15:35,184,364...35,195,725
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP Nevirapine metabolite results in decreased expression of HAO2 mRNA; Nevirapine results in decreased expression of HAO2 mRNA CTD PMID:23947594 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Hdc histidine decarboxylase decreases expression EXP Nevirapine metabolite results in decreased expression of HDC mRNA CTD PMID:23947594 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hgf hepatocyte growth factor decreases secretion ISO Nevirapine results in decreased secretion of HGF protein CTD PMID:21619898 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP Nevirapine metabolite results in increased expression of HMGCS2 mRNA; Nevirapine results in increased expression of HMGCS2 mRNA CTD PMID:23947594 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression EXP Nevirapine metabolite results in increased expression of HPGD mRNA CTD PMID:23947594 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression EXP Nevirapine metabolite results in decreased expression of HSD17B2 mRNA CTD PMID:23947594 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Ifng interferon gamma increases expression ISO
EXP
Nevirapine results in increased expression of IFNG protein CTD PMID:23947594 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igh-6 immunoglobulin heavy chain 6 increases expression EXP Nevirapine results in increased expression of IGH-6 mRNA CTD PMID:23947594 Ensembl chr 6:138,092,131...138,093,643 JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 increases expression EXP Nevirapine metabolite results in increased expression of IL22RA2 mRNA CTD PMID:23947594 NCBI chr 1:15,084,136...15,107,423
Ensembl chr 1:15,093,599...15,106,954
JBrowse link
G Il6 interleukin 6 decreases secretion ISO Nevirapine results in decreased secretion of IL6 protein CTD PMID:21619898 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inhbe inhibin subunit beta E decreases expression EXP Nevirapine metabolite results in decreased expression of INHBE mRNA CTD PMID:23947594 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Inmt indolethylamine N-methyltransferase increases expression EXP Nevirapine results in increased expression of INMT mRNA CTD PMID:23947594 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Insig2 insulin induced gene 2 increases expression EXP Nevirapine results in increased expression of INSIG2 mRNA CTD PMID:23947594 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Irgm immunity-related GTPase M decreases expression EXP Nevirapine results in decreased expression of IRGM mRNA CTD PMID:23947594 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression EXP Nevirapine results in increased expression of ITPR1 mRNA CTD PMID:23947594 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Klf15 Kruppel-like factor 15 increases expression EXP Nevirapine metabolite results in increased expression of KLF15 mRNA CTD PMID:23947594 NCBI chr 4:122,364,688...122,377,690
Ensembl chr 4:122,365,093...122,377,659
JBrowse link
G Krt18 keratin 18 increases expression ISO Nevirapine results in increased expression of KRT18 protein CTD PMID:19152342 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt23 keratin 23 increases expression EXP Nevirapine metabolite results in increased expression of KRT23 mRNA CTD PMID:23947594 NCBI chr10:87,391,623...87,407,634
Ensembl chr10:87,391,623...87,407,634
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO Nevirapine results in increased expression of LCAT protein CTD PMID:19667106 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lep leptin increases expression ISO Nevirapine results in increased expression of LEP mRNA CTD PMID:21619898 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lifr LIF receptor subunit alpha increases expression EXP Nevirapine metabolite results in increased expression of LIFR mRNA CTD PMID:23947594 NCBI chr 2:56,424,910...56,489,346
Ensembl chr 2:56,426,367...56,489,415
JBrowse link
G Lilrb3l leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like decreases expression EXP Nevirapine results in decreased expression of LILRB3L mRNA CTD PMID:23947594 NCBI chr 1:63,759,638...63,849,278
Ensembl chr 1:63,759,638...64,013,289
JBrowse link
G Lipg lipase G, endothelial type decreases expression EXP Nevirapine metabolite results in decreased expression of LIPG mRNA; Nevirapine results in decreased expression of LIPG mRNA CTD PMID:23947594 NCBI chr18:70,903,528...70,924,434
Ensembl chr18:70,901,710...70,924,708
JBrowse link
G Lpin1 lipin 1 increases expression EXP Nevirapine metabolite results in increased expression of LPIN1 mRNA CTD PMID:23947594 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lpl lipoprotein lipase increases expression ISO Nevirapine results in increased expression of LPL mRNA CTD PMID:21619898 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 increases expression EXP Nevirapine metabolite results in increased expression of LRG1 mRNA CTD PMID:23947594 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Ly86 lymphocyte antigen 86 decreases expression EXP Nevirapine results in decreased expression of LY86 mRNA CTD PMID:23947594 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
JBrowse link
G Meox2 mesenchyme homeobox 2 increases expression EXP Nevirapine results in increased expression of MEOX2 mRNA CTD PMID:23947594 NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238
JBrowse link
G Mgp matrix Gla protein increases expression EXP Nevirapine results in increased expression of MGP mRNA CTD PMID:23947594 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression EXP Nevirapine metabolite results in increased expression of MRC1 mRNA CTD PMID:23947594 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Ms4a7 membrane spanning 4-domains A7 decreases expression EXP Nevirapine results in decreased expression of MS4A7 mRNA CTD PMID:23947594 NCBI chr 1:227,490,777...227,506,819
Ensembl chr 1:227,490,777...227,506,822
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP Nevirapine metabolite results in increased expression of NAMPT mRNA CTD PMID:23947594 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 increases expression EXP Nevirapine results in increased expression of NDUFAF4 mRNA CTD PMID:23947594 NCBI chr 5:39,251,370...39,256,542
Ensembl chr 5:39,251,337...39,257,512
JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 increases expression ISO Nevirapine results in increased expression of NLRC5 CTD PMID:26626330 NCBI chr19:10,904,381...11,006,202
Ensembl chr19:10,905,542...10,976,396
JBrowse link
G Npas2 neuronal PAS domain protein 2 decreases expression EXP Nevirapine metabolite results in decreased expression of NPAS2 mRNA; Nevirapine results in decreased expression of NPAS2 mRNA CTD PMID:23947594 NCBI chr 9:45,901,262...46,081,880
Ensembl chr 9:45,901,741...46,081,880
JBrowse link
G Nptx2 neuronal pentraxin 2 increases expression EXP Nevirapine results in increased expression of NPTX2 mRNA CTD PMID:23947594 NCBI chr12:12,014,638...12,025,547
Ensembl chr12:12,013,911...12,025,549
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression EXP Nevirapine metabolite results in decreased expression of NR1D1 mRNA CTD PMID:23947594 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Nevirapine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Nevirapine results in increased activity of NR1I3 protein] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP Nevirapine metabolite results in decreased expression of NREP mRNA; Nevirapine results in decreased expression of NREP mRNA CTD PMID:23947594 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G P2rx7 purinergic receptor P2X 7 decreases expression EXP Nevirapine results in decreased expression of P2RX7 mRNA CTD PMID:23947594 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 decreases expression EXP Nevirapine results in decreased expression of PCP4L1 mRNA CTD PMID:23947594 NCBI chr13:89,542,377...89,565,920
Ensembl chr13:89,542,378...89,565,813
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Nevirapine metabolite results in increased expression of PDK4 mRNA CTD PMID:23947594 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 increases expression EXP Nevirapine results in increased expression of PIK3IP1 mRNA CTD PMID:23947594 NCBI chr14:83,559,397...83,572,481
Ensembl chr14:83,560,541...83,572,473
JBrowse link
G Pir pirin increases expression EXP Nevirapine metabolite results in increased expression of PIR mRNA CTD PMID:23947594 NCBI chr  X:31,852,322...31,968,152
Ensembl chr  X:31,852,323...31,968,152
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP Nevirapine metabolite results in increased expression of PNPLA2 mRNA CTD PMID:23947594 NCBI chr 1:214,434,638...214,439,720
Ensembl chr 1:214,434,626...214,439,720
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Nevirapine metabolite results in increased expression of POR mRNA; Nevirapine results in increased expression of POR mRNA CTD PMID:23947594 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Nevirapine results in increased expression of PPARG mRNA CTD PMID:21619898 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression EXP Nevirapine metabolite results in decreased expression of PPP2R2B mRNA; Nevirapine results in decreased expression of PPP2R2B mRNA CTD PMID:23947594 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Prf1 perforin 1 decreases expression EXP Nevirapine metabolite results in decreased expression of PRF1 mRNA CTD PMID:23947594 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 decreases expression EXP Nevirapine metabolite results in decreased expression of PYCR1 mRNA CTD PMID:23947594 NCBI chr10:109,817,300...109,822,218
Ensembl chr10:109,818,177...109,821,807
JBrowse link
G Rbm3 RNA binding motif protein 3 increases expression EXP Nevirapine results in increased expression of RBM3 mRNA CTD PMID:23947594 NCBI chr  X:15,098,880...15,102,344
Ensembl chr  X:15,098,904...15,102,340
JBrowse link
G Retreg1 reticulophagy regulator 1 increases expression EXP Nevirapine metabolite results in increased expression of RETREG1 mRNA; Nevirapine results in increased expression of RETREG1 mRNA CTD PMID:23947594 NCBI chr 2:78,391,921...78,401,569
Ensembl chr 2:78,391,921...78,399,987
JBrowse link
G Rhbdd2 rhomboid domain containing 2 increases expression EXP Nevirapine results in increased expression of RHBDD2 mRNA CTD PMID:23947594 NCBI chr12:24,091,132...24,102,081
Ensembl chr12:24,092,004...24,102,084
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog decreases expression EXP Nevirapine metabolite results in decreased expression of RPRM mRNA CTD PMID:23947594 NCBI chr 3:39,595,301...39,596,718
Ensembl chr 3:39,595,301...39,596,718
JBrowse link
G S100a7a S100 calcium binding protein A7A increases expression EXP Nevirapine metabolite results in increased expression of S100A7A mRNA CTD PMID:23947594 NCBI chr 2:190,058,093...190,063,132
Ensembl chr 2:190,058,093...190,062,534
JBrowse link
G Scp2 sterol carrier protein 2 increases expression ISO Nevirapine results in increased expression of SCP2 CTD PMID:26626330 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Slamf9 SLAM family member 9 decreases expression EXP Nevirapine results in decreased expression of SLAMF9 mRNA CTD PMID:23947594 NCBI chr13:90,836,419...90,856,913
Ensembl chr13:90,836,361...90,839,411
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Nevirapine metabolite results in decreased expression of SLC34A2 mRNA CTD PMID:23947594 NCBI chr14:60,257,211...60,276,516
Ensembl chr14:60,256,712...60,276,794
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 protein CTD PMID:16030158 NCBI chr16:20,297,414...20,307,401
Ensembl chr16:20,297,414...20,307,400
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression
decreases expression
ISO
EXP
Nevirapine results in increased expression of SREBF1 mRNA
Nevirapine metabolite results in decreased expression of SREBF1 mRNA
CTD PMID:21619898, PMID:23947594 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases activity EXP Nevirapine metabolite results in increased activity of SULT1A1 protein; Nevirapine results in increased activity of SULT1A1 protein CTD PMID:27417440 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tg thyroglobulin increases expression ISO Nevirapine results in increased expression of TG mRNA; Nevirapine results in increased expression of TG protein CTD PMID:16030158 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tmem159 transmembrane protein 159 decreases expression EXP Nevirapine results in decreased expression of TMEM159 mRNA CTD PMID:23947594 NCBI chr 1:189,870,596...189,889,485
Ensembl chr 1:189,870,622...189,889,484
JBrowse link
G Tmem64 transmembrane protein 64 increases expression EXP Nevirapine metabolite results in increased expression of TMEM64 mRNA; Nevirapine results in increased expression of TMEM64 mRNA CTD PMID:23947594 NCBI chr 5:28,850,864...28,898,203
Ensembl chr 5:28,850,950...28,867,227
JBrowse link
G Tox3 TOX high mobility group box family member 3 increases expression EXP Nevirapine results in increased expression of TOX3 mRNA CTD PMID:23947594 NCBI chr19:18,079,022...18,188,366
Ensembl chr19:18,079,094...18,188,330
JBrowse link
G Tpo thyroid peroxidase increases expression ISO Nevirapine results in increased expression of TPO mRNA; Nevirapine results in increased expression of TPO protein CTD PMID:16030158 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
G Trim24 tripartite motif-containing 24 decreases expression EXP Nevirapine results in decreased expression of TRIM24 mRNA CTD PMID:23947594 NCBI chr 4:65,632,278...65,684,746
Ensembl chr 4:65,637,407...65,684,743
JBrowse link
G Trim63 tripartite motif containing 63 increases expression EXP Nevirapine metabolite results in increased expression of TRIM63 mRNA CTD PMID:23947594 NCBI chr 5:152,533,362...152,547,138
Ensembl chr 5:152,533,349...152,547,179
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression EXP Nevirapine results in increased expression of TSC22D3 mRNA CTD PMID:23947594 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 mRNA; [Nevirapine co-treated with TSHB protein] results in increased expression of SLC5A5 protein; Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]; sodium perchlorate inhibits the reaction [Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]] CTD PMID:16030158 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO Nevirapine results in increased expression of TSHR mRNA CTD PMID:16030158 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression EXP Nevirapine results in increased expression of TSKU mRNA CTD PMID:23947594 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591
JBrowse link
G Ucp1 uncoupling protein 1 increases expression ISO Nevirapine results in increased expression of UCP1 CTD PMID:16038477 NCBI chr19:24,456,976...24,464,808
Ensembl chr19:24,456,976...24,464,807
JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP Nevirapine metabolite results in increased expression of UCP3 mRNA CTD PMID:23947594 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Nevirapine metabolite results in increased expression of VCAM1 mRNA CTD PMID:23947594 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Nevirapine results in decreased expression of VEGFA mRNA CTD PMID:19152342 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vsnl1 visinin-like 1 decreases expression EXP Nevirapine metabolite results in decreased expression of VSNL1 mRNA; Nevirapine results in decreased expression of VSNL1 mRNA CTD PMID:23947594 NCBI chr 6:37,001,360...37,121,969
Ensembl chr 6:37,001,356...37,122,023
JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 increases expression EXP Nevirapine results in increased expression of ZAP70 mRNA CTD PMID:23947594 NCBI chr 9:43,331,149...43,353,097
Ensembl chr 9:43,331,155...43,353,113
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      atom 19782
        nonmetal atom 19657
          nitrogen atom 18539
            nitrogen molecular entity 18539
              organonitrogen compound 18309
                organonitrogen heterocyclic compound 17460
                  dipyridodiazepine 123
                    12-hydroxynevirapine 0
                    nevirapine + 123
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  organic heteropolycyclic compound 17820
                                    organic heterotricyclic compound 14571
                                      dipyridodiazepine 123
                                        12-hydroxynevirapine 0
                                        nevirapine + 123
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.