Csnk1e (casein kinase 1, epsilon) - Rat Genome Database

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Gene: Csnk1e (casein kinase 1, epsilon) Rattus norvegicus
Analyze
Symbol: Csnk1e
Name: casein kinase 1, epsilon
RGD ID: 62045
Description: Enables protein serine/threonine kinase activity. Involved in cellular response to nerve growth factor stimulus; circadian behavior; and positive regulation of amyloid-beta formation. Located in growth cone and neuronal cell body. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to several human genes including CSNK1E (casein kinase 1 epsilon); PARTICIPATES IN Hedgehog signaling pathway; p53 signaling pathway; ribosome biogenesis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: casein kinase 1 epsilon; casein kinase I; casein kinase I isoform epsilon
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,863,726 - 112,887,338 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7112,863,731 - 112,884,101 (-)EnsemblGRCr8
mRatBN7.27110,983,322 - 111,006,926 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,983,318 - 111,006,794 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7112,733,871 - 112,752,233 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,957,407 - 114,975,770 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,926,771 - 114,945,137 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,651,976 - 120,675,559 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,651,881 - 120,672,359 (-)Ensemblrn6Rnor6.0
Rnor_5.07120,644,806 - 120,665,192 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47117,402,718 - 117,420,764 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7107,318,733 - 107,336,768 (-)NCBICelera
RGSC_v3.17117,436,947 - 117,454,994 (-)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-nitrophenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (EXP)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
ferric oxide  (ISO)
fipronil  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
isobutanol  (ISO)
lead(0)  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
N-Vinyl-2-pyrrolidone  (EXP)
niclosamide  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
propiconazole  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
theophylline  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
Tributyltin oxide  (EXP)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. An inhibitor of casein kinase I epsilon induces phase delays in circadian rhythms under free-running and entrained conditions. Badura L, etal., J Pharmacol Exp Ther. 2007 Aug;322(2):730-8. Epub 2007 May 14.
2. Neurite outgrowth of mature retinal ganglion cells and PC12 cells requires activity of CK1delta and CK1epsilon. Bischof J, etal., PLoS One. 2011;6(6):e20857. doi: 10.1371/journal.pone.0020857. Epub 2011 Jun 16.
3. Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. Bryja V, etal., J Cell Sci. 2007 Feb 15;120(Pt 4):586-95. Epub 2007 Jan 23.
4. Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I. Flajolet M, etal., Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4159-64. Epub 2007 Feb 27.
5. Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma. Fuja TJ, etal., Cancer Res. 2004 Feb 1;64(3):942-51.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease. Ghoshal N, etal., Am J Pathol. 1999 Oct;155(4):1163-72.
8. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Cloning and characterization of rat casein kinase 1epsilon. Takano A, etal., FEBS Lett 2000 Jul 14;477(1-2):106-12.
17. The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer. Wang Z, etal., Theranostics. 2021 Mar 4;11(9):4421-4435. doi: 10.7150/thno.53901. eCollection 2021.
18. CK1delta and CK1epsilon are components of human 40S subunit precursors required for cytoplasmic 40S maturation. Zemp I, etal., J Cell Sci. 2014 Mar 15;127(Pt 6):1242-53. doi: 10.1242/jcs.138719. Epub 2014 Jan 14.
Additional References at PubMed
PMID:12270714   PMID:12556519   PMID:14701732   PMID:14722104   PMID:14966280   PMID:15917222   PMID:17027228   PMID:17606995   PMID:19414593   PMID:21564097   PMID:21709260   PMID:21930935  
PMID:22549116   PMID:22681889   PMID:23109420   PMID:25245819   PMID:25500533   PMID:37787983  


Genomics

Comparative Map Data
Csnk1e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87112,863,726 - 112,887,338 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7112,863,731 - 112,884,101 (-)EnsemblGRCr8
mRatBN7.27110,983,322 - 111,006,926 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,983,318 - 111,006,794 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7112,733,871 - 112,752,233 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,957,407 - 114,975,770 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07114,926,771 - 114,945,137 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,651,976 - 120,675,559 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,651,881 - 120,672,359 (-)Ensemblrn6Rnor6.0
Rnor_5.07120,644,806 - 120,665,192 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47117,402,718 - 117,420,764 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7107,318,733 - 107,336,768 (-)NCBICelera
RGSC_v3.17117,436,947 - 117,454,994 (-)NCBI
Cytogenetic Map7q34NCBI
CSNK1E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,290,691 - 38,318,084 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,290,691 - 38,320,044 (-)Ensemblhg38GRCh38
GRCh372238,686,697 - 38,714,089 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,016,643 - 37,044,035 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342237,011,197 - 37,037,913NCBI
Celera2222,491,424 - 22,518,819 (-)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2221,653,091 - 21,680,820 (-)NCBIHuRef
CHM1_12238,645,663 - 38,672,968 (-)NCBICHM1_1
T2T-CHM13v2.02238,754,994 - 38,782,389 (-)NCBIT2T-CHM13v2.0
Csnk1e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,302,054 - 79,339,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,302,056 - 79,339,767 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381579,417,852 - 79,455,579 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,417,856 - 79,455,566 (-)Ensemblmm10GRCm38
MGSCv371579,248,282 - 79,272,487 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361579,245,111 - 79,269,262 (-)NCBIMGSCv36mm8
Celera1581,541,134 - 81,565,319 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.71NCBI
Csnk1e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,560,900 - 24,591,669 (-)Ensembl
ChiLan1.0NW_00495541324,560,889 - 24,591,669 (-)NCBIChiLan1.0ChiLan1.0
CSNK1E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,146,034 - 48,192,237 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12250,823,184 - 50,880,768 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,202,599 - 19,229,344 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12237,027,094 - 37,140,249 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,027,094 - 37,072,942 (-)EnsemblpanPan2panpan1.1
CSNK1E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,386,646 - 26,412,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1026,393,033 - 26,411,624 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1026,334,633 - 26,368,458 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01027,170,481 - 27,203,064 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1027,180,836 - 27,265,335 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,891,565 - 26,924,098 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01027,202,855 - 27,235,392 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,379,859 - 27,412,401 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CSNK1E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,594,934 - 9,620,476 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.159,594,461 - 9,620,483 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,877,173 - 6,902,925 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CSNK1E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11920,992,927 - 21,025,866 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1920,998,009 - 21,022,576 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666045104,722,716 - 104,775,265 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Csnk1e
104 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:124
Count of miRNA genes:109
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000018126
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
RH129776  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27110,989,098 - 110,989,251 (+)MAPPERmRatBN7.2
Rnor_6.07120,657,750 - 120,657,902NCBIRnor6.0
Rnor_5.07120,650,580 - 120,650,732UniSTSRnor5.0
RGSC_v3.47117,406,389 - 117,406,541UniSTSRGSC3.4
Celera7107,322,404 - 107,322,556UniSTS
RH 3.4 Map7848.0UniSTS
Cytogenetic Map7q34UniSTS
RH137940  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27110,984,187 - 110,984,348 (+)MAPPERmRatBN7.2
Rnor_6.07120,652,840 - 120,653,000NCBIRnor6.0
Rnor_5.07120,645,670 - 120,645,830UniSTSRnor5.0
RGSC_v3.47117,401,479 - 117,401,639UniSTSRGSC3.4
Celera7107,317,494 - 107,317,654UniSTS
RH 3.4 Map7848.0UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018126   ⟹   ENSRNOP00000018126
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,864,452 - 112,884,101 (-)Ensembl
mRatBN7.2 Ensembl7110,984,045 - 111,006,550 (-)Ensembl
Rnor_6.0 Ensembl7120,652,697 - 120,672,350 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087800   ⟹   ENSRNOP00000073559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,869,607 - 112,884,101 (-)Ensembl
mRatBN7.2 Ensembl7110,989,201 - 111,006,550 (-)Ensembl
Rnor_6.0 Ensembl7120,657,852 - 120,672,350 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000088424   ⟹   ENSRNOP00000074993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,863,731 - 112,884,101 (-)Ensembl
mRatBN7.2 Ensembl7110,983,318 - 111,006,550 (-)Ensembl
Rnor_6.0 Ensembl7120,651,881 - 120,672,359 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096240   ⟹   ENSRNOP00000084410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,863,731 - 112,875,755 (-)Ensembl
mRatBN7.2 Ensembl7110,985,428 - 111,006,550 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105387   ⟹   ENSRNOP00000078173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7110,989,512 - 111,006,794 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119470   ⟹   ENSRNOP00000084112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7112,865,444 - 112,884,101 (-)Ensembl
mRatBN7.2 Ensembl7110,985,038 - 111,006,550 (-)Ensembl
RefSeq Acc Id: NM_031617   ⟹   NP_113805
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,863,731 - 112,887,313 (-)NCBI
mRatBN7.27110,983,322 - 111,006,911 (-)NCBI
Rnor_6.07120,654,079 - 120,672,350 (-)NCBI
Rnor_5.07120,644,806 - 120,665,192 (-)NCBI
RGSC_v3.47117,402,718 - 117,420,764 (-)RGD
Celera7107,318,733 - 107,336,768 (-)RGD
Sequence:
RefSeq Acc Id: XM_039079799   ⟹   XP_038935727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,863,726 - 112,887,338 (-)NCBI
mRatBN7.27110,983,322 - 111,006,925 (-)NCBI
RefSeq Acc Id: XM_039079805   ⟹   XP_038935733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,868,335 - 112,887,338 (-)NCBI
mRatBN7.27110,987,928 - 111,006,926 (-)NCBI
RefSeq Acc Id: XM_063264172   ⟹   XP_063120242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,868,335 - 112,886,414 (-)NCBI
RefSeq Acc Id: XM_063264173   ⟹   XP_063120243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,868,335 - 112,887,069 (-)NCBI
RefSeq Acc Id: XM_063264174   ⟹   XP_063120244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,863,726 - 112,887,034 (-)NCBI
RefSeq Acc Id: XM_063264175   ⟹   XP_063120245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87112,868,335 - 112,877,888 (-)NCBI
RefSeq Acc Id: NP_113805   ⟸   NM_031617
- UniProtKB: Q9JJ76 (UniProtKB/TrEMBL),   A0A8I5ZYG3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018126   ⟸   ENSRNOT00000018126
Ensembl Acc Id: ENSRNOP00000073559   ⟸   ENSRNOT00000087800
Ensembl Acc Id: ENSRNOP00000074993   ⟸   ENSRNOT00000088424
RefSeq Acc Id: XP_038935727   ⟸   XM_039079799
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZZ88 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935733   ⟸   XM_039079805
- Peptide Label: isoform X5
- UniProtKB: Q9JJ75 (UniProtKB/TrEMBL),   A6HSR9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000084112   ⟸   ENSRNOT00000119470
Ensembl Acc Id: ENSRNOP00000084410   ⟸   ENSRNOT00000096240
Ensembl Acc Id: ENSRNOP00000078173   ⟸   ENSRNOT00000105387
RefSeq Acc Id: XP_063120244   ⟸   XM_063264174
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZYG3 (UniProtKB/TrEMBL),   Q9JJ76 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120243   ⟸   XM_063264173
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y728 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120242   ⟸   XM_063264172
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y728 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120245   ⟸   XM_063264175
- Peptide Label: isoform X4
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99PS2-F1-model_v2 AlphaFold Q99PS2 1-506 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62045 AgrOrtholog
BioCyc Gene G2FUF-32762 BioCyc
Ensembl Genes ENSRNOG00000013076 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018126.5 UniProtKB/TrEMBL
  ENSRNOT00000087800 ENTREZGENE
  ENSRNOT00000087800.3 UniProtKB/TrEMBL
  ENSRNOT00000088424 ENTREZGENE
  ENSRNOT00000088424.3 UniProtKB/TrEMBL
  ENSRNOT00000096240 ENTREZGENE
  ENSRNOT00000096240.2 UniProtKB/TrEMBL
  ENSRNOT00000119470.2 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CK1_Ser-Thr_kinase UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_prot_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:58822 UniProtKB/TrEMBL
NCBI Gene 58822 ENTREZGENE
PANTHER CASEIN KINASE-RELATED UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Csnk1e PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013076 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A0G2K9G9_RAT UniProtKB/TrEMBL
  A0A8I5Y728 ENTREZGENE
  A0A8I5ZYG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZZ88 ENTREZGENE, UniProtKB/TrEMBL
  A6HSR7_RAT UniProtKB/TrEMBL
  A6HSR8_RAT UniProtKB/TrEMBL
  A6HSR9 ENTREZGENE, UniProtKB/TrEMBL
  Q99PS2_RAT UniProtKB/TrEMBL
  Q9JJ75 ENTREZGENE, UniProtKB/TrEMBL
  Q9JJ76 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Csnk1e  casein kinase 1, epsilon      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression predominantly expressed in the suprachiasmatic nucleus of the brain 631233