Fgf12 (fibroblast growth factor 12) - Rat Genome Database

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Gene: Fgf12 (fibroblast growth factor 12) Rattus norvegicus
Analyze
Symbol: Fgf12
Name: fibroblast growth factor 12
RGD ID: 620163
Description: Enables sodium channel regulator activity and transmembrane transporter binding activity. Involved in regulation of membrane depolarization and regulation of sodium ion transmembrane transport. Predicted to be located in synapse. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 47. Orthologous to human FGF12 (fibroblast growth factor 12); PARTICIPATES IN melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FGF-12; Fgf1a; FHF-1; Fhf1; Fhf1b; fibroblast growth factor 1a; fibroblast growth factor homologous factor 1; fibroblast growth factor homologous factor 1b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81185,501,947 - 86,069,543 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1185,501,936 - 86,069,543 (+)EnsemblGRCr8
mRatBN7.21171,997,151 - 72,564,757 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1171,997,099 - 72,562,607 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1180,835,781 - 81,403,369 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01173,470,763 - 74,038,380 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01172,528,137 - 73,092,997 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01175,606,360 - 76,171,078 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1175,905,443 - 76,168,989 (+)Ensemblrn6Rnor6.0
Rnor_5.01178,647,628 - 79,212,339 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41174,208,696 - 74,481,037 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1171,257,632 - 71,518,401 (+)NCBICelera
RGSC_v3.11174,266,284 - 74,538,626 (+)NCBI
Cytogenetic Map11q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cannabidiol  (EXP)
choline  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dieldrin  (EXP)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
fonofos  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
indole-3-methanol  (EXP)
kojic acid  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
Moniliformin  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nitrofen  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP)
parathion  (ISO)
PCB138  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phenytoin  (EXP)
potassium chromate  (ISO)
potassium dichromate  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
terbufos  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
nucleolus  (ISO)
nucleus  (IBA,IEA,ISO)
synapse  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN). Liu Cj, etal., J Biol Chem 2001 Jun 1;276(22):18925-33.
3. Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B. Liu CJ, etal., J Biol Chem. 2003 Jan 10;278(2):1029-36. Epub 2002 Oct 24.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs. Olsen SK, etal., J Biol Chem 2003 Sep 5;278(36):34226-36. Epub 2003 Jun 17.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8790420   PMID:17678857   PMID:25724910   PMID:27164707   PMID:27470512   PMID:35093630  


Genomics

Comparative Map Data
Fgf12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81185,501,947 - 86,069,543 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1185,501,936 - 86,069,543 (+)EnsemblGRCr8
mRatBN7.21171,997,151 - 72,564,757 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1171,997,099 - 72,562,607 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1180,835,781 - 81,403,369 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01173,470,763 - 74,038,380 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01172,528,137 - 73,092,997 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01175,606,360 - 76,171,078 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1175,905,443 - 76,168,989 (+)Ensemblrn6Rnor6.0
Rnor_5.01178,647,628 - 79,212,339 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41174,208,696 - 74,481,037 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1171,257,632 - 71,518,401 (+)NCBICelera
RGSC_v3.11174,266,284 - 74,538,626 (+)NCBI
Cytogenetic Map11q22NCBI
FGF12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383192,139,390 - 192,727,541 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3192,139,390 - 192,767,764 (-)Ensemblhg38GRCh38
GRCh373191,857,179 - 192,445,330 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363193,342,413 - 193,928,066 (-)NCBIBuild 36Build 36hg18NCBI36
Build 343193,342,427 - 193,608,714NCBI
Celera3190,287,307 - 190,871,367 (-)NCBICelera
Cytogenetic Map3q28-q29NCBI
HuRef3189,257,496 - 189,843,496 (-)NCBIHuRef
CHM1_13191,820,291 - 192,408,216 (-)NCBICHM1_1
T2T-CHM13v2.03194,835,241 - 195,423,480 (-)NCBIT2T-CHM13v2.0
Fgf12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391627,976,535 - 28,571,995 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1627,978,850 - 28,571,820 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381628,157,783 - 28,753,243 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1628,160,098 - 28,753,068 (-)Ensemblmm10GRCm38
MGSCv371628,160,184 - 28,753,288 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361628,075,331 - 28,672,949 (-)NCBIMGSCv36mm8
Celera1628,680,820 - 29,265,446 (-)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1619.38NCBI
Fgf12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542016,070,096 - 16,306,103 (+)Ensembl
ChiLan1.0NW_00495542015,783,184 - 16,310,743 (+)NCBIChiLan1.0ChiLan1.0
FGF12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22190,077,177 - 190,666,458 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13190,081,896 - 190,669,838 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03189,430,811 - 190,017,254 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13199,776,475 - 200,359,141 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3199,778,545 - 200,358,744 (-)EnsemblpanPan2panpan1.1
FGF12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13423,818,445 - 24,357,825 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3423,819,686 - 24,357,373 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3427,906,449 - 28,448,823 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03423,761,357 - 24,303,983 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3423,764,444 - 24,302,991 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13423,789,790 - 24,338,922 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03423,765,747 - 24,309,079 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03424,006,536 - 24,549,544 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fgf12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602121,869,101 - 122,376,824 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367112,045,080 - 2,375,896 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367111,873,030 - 2,378,028 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13129,240,083 - 129,817,911 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113129,237,500 - 129,817,992 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213138,752,214 - 138,983,183 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11586,252,816 - 86,836,363 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604159,914,424 - 60,500,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473065,038,077 - 65,284,083 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473064,743,724 - 65,288,816 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Fgf12
3081 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:29
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000002650, ENSRNOT00000071586
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)118295102896351019Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
D11Mco1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81185,878,696 - 85,878,932 (+)Marker Load Pipeline
mRatBN7.21172,373,932 - 72,374,168 (+)MAPPERmRatBN7.2
Rnor_6.01175,980,425 - 75,980,660NCBIRnor6.0
Rnor_5.01179,022,025 - 79,022,260UniSTSRnor5.0
RGSC_v3.41174,287,096 - 74,287,332RGDRGSC3.4
RGSC_v3.41174,287,097 - 74,287,332UniSTSRGSC3.4
Celera1171,329,739 - 71,329,974UniSTS
RGSC_v3.11174,344,685 - 74,344,921RGD
Cytogenetic Map11q22UniSTS
D11Arb13  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81185,958,731 - 85,958,915 (+)Marker Load Pipeline
mRatBN7.21172,453,971 - 72,454,154 (+)MAPPERmRatBN7.2
Rnor_6.01176,060,599 - 76,060,781NCBIRnor6.0
Rnor_5.01179,102,266 - 79,102,448UniSTSRnor5.0
RGSC_v3.41174,367,678 - 74,367,862RGDRGSC3.4
RGSC_v3.41174,367,680 - 74,367,862UniSTSRGSC3.4
Celera1171,409,911 - 71,410,093UniSTS
RGSC_v3.11174,425,267 - 74,425,451RGD
Cytogenetic Map11q22UniSTS
D11Got112  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,462,243 - 72,462,449 (+)MAPPERmRatBN7.2
Rnor_6.01176,068,871 - 76,069,076NCBIRnor6.0
Rnor_5.01179,110,538 - 79,110,743UniSTSRnor5.0
RGSC_v3.41174,375,952 - 74,376,157UniSTSRGSC3.4
Celera1171,418,099 - 71,418,304UniSTS
Cytogenetic Map11q22UniSTS
RH142893  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81185,807,421 - 85,807,533 (+)Marker Load Pipeline
mRatBN7.21172,302,653 - 72,302,765 (+)MAPPERmRatBN7.2
Rnor_6.01175,909,150 - 75,909,261NCBIRnor6.0
Rnor_5.01178,950,750 - 78,950,861UniSTSRnor5.0
RGSC_v3.41174,212,403 - 74,212,514UniSTSRGSC3.4
Celera1171,261,339 - 71,261,450UniSTS
RH 3.4 Map11580.9UniSTS
Cytogenetic Map11q22UniSTS
BF397888  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,413,923 - 72,414,074 (+)MAPPERmRatBN7.2
Rnor_6.01176,020,547 - 76,020,697NCBIRnor6.0
Rnor_5.01179,062,147 - 79,062,297UniSTSRnor5.0
RGSC_v3.41174,327,526 - 74,327,676UniSTSRGSC3.4
Celera1171,369,806 - 71,369,956UniSTS
RH 3.4 Map11595.9UniSTS
Cytogenetic Map11q22UniSTS
RH140156  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,562,547 - 72,562,748 (+)MAPPERmRatBN7.2
Rnor_6.01176,168,871 - 76,169,071NCBIRnor6.0
Rnor_5.01179,210,132 - 79,210,332UniSTSRnor5.0
RGSC_v3.41174,481,117 - 74,481,317UniSTSRGSC3.4
Celera1171,518,481 - 71,518,681UniSTS
Cytogenetic Map11q22UniSTS
RH140530  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,562,505 - 72,562,664 (+)MAPPERmRatBN7.2
Rnor_6.01176,168,829 - 76,168,987NCBIRnor6.0
Rnor_5.01179,210,090 - 79,210,248UniSTSRnor5.0
RGSC_v3.41174,481,075 - 74,481,233UniSTSRGSC3.4
Celera1171,518,439 - 71,518,597UniSTS
RH 3.4 Map11593.5UniSTS
Cytogenetic Map11q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 13 80 196 91 90 59 81 59 6 383 202 20 176 99 120 31 26 26

Sequence


Ensembl Acc Id: ENSRNOT00000002650   ⟹   ENSRNOP00000002650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1185,501,936 - 86,069,543 (+)Ensembl
mRatBN7.2 Ensembl1171,997,099 - 72,562,607 (+)Ensembl
Rnor_6.0 Ensembl1175,905,443 - 76,168,791 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000071586   ⟹   ENSRNOP00000066842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1172,540,927 - 72,562,607 (+)Ensembl
Rnor_6.0 Ensembl1176,147,205 - 76,168,989 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112688   ⟹   ENSRNOP00000085066
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1172,186,031 - 72,562,607 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000158744   ⟹   ENSRNOP00000111324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1185,801,758 - 86,069,543 (+)Ensembl
RefSeq Acc Id: NM_001395084   ⟹   NP_001382013
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81185,501,947 - 86,069,543 (+)NCBI
mRatBN7.21171,997,151 - 72,564,757 (+)NCBI
RefSeq Acc Id: NM_130814   ⟹   NP_570827
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81185,801,758 - 86,069,543 (+)NCBI
mRatBN7.21172,296,990 - 72,564,757 (+)NCBI
Rnor_6.01175,905,443 - 76,168,791 (+)NCBI
Rnor_5.01178,647,628 - 79,212,339 (+)NCBI
RGSC_v3.41174,208,696 - 74,481,037 (+)RGD
Celera1171,257,632 - 71,518,401 (+)RGD
Sequence:
RefSeq Acc Id: XM_017597854   ⟹   XP_017453343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81185,693,335 - 86,069,543 (+)NCBI
mRatBN7.21172,188,575 - 72,564,757 (+)NCBI
Rnor_6.01175,795,160 - 76,171,078 (+)NCBI
Sequence:
RefSeq Acc Id: NP_570827   ⟸   NM_130814
- Peptide Label: isoform 1
- UniProtKB: P61150 (UniProtKB/Swiss-Prot),   A0A7U3L6G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453343   ⟸   XM_017597854
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2F9 (UniProtKB/TrEMBL),   A6JRX6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002650   ⟸   ENSRNOT00000002650
Ensembl Acc Id: ENSRNOP00000066842   ⟸   ENSRNOT00000071586
Ensembl Acc Id: ENSRNOP00000085066   ⟸   ENSRNOT00000112688
RefSeq Acc Id: NP_001382013   ⟸   NM_001395084
- Peptide Label: isoform 2
- UniProtKB: A6JRX5 (UniProtKB/TrEMBL),   A6JRX6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111324   ⟸   ENSRNOT00000158744

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61150-F1-model_v2 AlphaFold P61150 1-243 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620163 AgrOrtholog
BioCyc Gene G2FUF-20959 BioCyc
Ensembl Genes ENSRNOG00000001931 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000090378 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000002650 ENTREZGENE
  ENSRNOT00000002650.5 UniProtKB/Swiss-Prot
  ENSRNOT00000158744 ENTREZGENE
Gene3D-CATH 2.80.10.50 UniProtKB/Swiss-Prot
InterPro Fibroblast_GF_fam UniProtKB/Swiss-Prot
  IL1/FGF UniProtKB/Swiss-Prot
KEGG Report rno:170630 UniProtKB/Swiss-Prot
NCBI Gene 170630 ENTREZGENE
PANTHER PTHR11486 UniProtKB/Swiss-Prot
Pfam FGF UniProtKB/Swiss-Prot
PhenoGen Fgf12 PhenoGen
PRINTS HBGFFGF UniProtKB/Swiss-Prot
  IL1HBGF UniProtKB/Swiss-Prot
PROSITE HBGF_FGF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001931 RatGTEx
  ENSRNOG00000090378 RatGTEx
SMART FGF UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot
UniProt A0A7U3L6G2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2F9 ENTREZGENE
  A6JRX4_RAT UniProtKB/TrEMBL
  A6JRX5 ENTREZGENE, UniProtKB/TrEMBL
  A6JRX6 ENTREZGENE, UniProtKB/TrEMBL
  FGF12_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary O35339 UniProtKB/Swiss-Prot
  P70376 UniProtKB/Swiss-Prot
  Q924B4 UniProtKB/Swiss-Prot
  Q92912 UniProtKB/Swiss-Prot
  Q93001 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-08-06 Fgf12  fibroblast growth factor 12      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN) 632803
gene_product member of the fibroblast growth factor family 632803