Slc30a1 (solute carrier family 30 member 1) - Rat Genome Database

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Gene: Slc30a1 (solute carrier family 30 member 1) Rattus norvegicus
Analyze
Symbol: Slc30a1
Name: solute carrier family 30 member 1
RGD ID: 61918
Description: Enables calcium channel inhibitor activity and zinc:proton antiporter activity. Involved in several processes, including detoxification of cadmium ion; metal ion transport; and regulation of postsynapse organization. Acts upstream of or within zinc ion transport. Located in T-tubule; dendrite; and postsynaptic density. Is active in Schaffer collateral - CA1 synapse and postsynaptic density membrane. Orthologous to human SLC30A1 (solute carrier family 30 member 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: proton-coupled zinc antiporter SLC30A1; solute carrier family 30 (zinc transporter) member 1; solute carrier family 30 (zinc transporter), member 1; solute carrier family 30, member 1; zinc transporter 1; znT-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813106,022,019 - 106,025,892 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13106,022,019 - 106,025,892 (+)EnsemblGRCr8
mRatBN7.213103,491,037 - 103,494,910 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,491,037 - 103,494,910 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13106,010,977 - 106,014,850 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013107,394,814 - 107,398,687 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013104,609,816 - 104,613,689 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013110,677,810 - 110,681,683 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,677,810 - 110,681,683 (+)Ensemblrn6Rnor6.0
Rnor_5.013115,236,547 - 115,240,420 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413107,980,864 - 107,986,519 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera13102,913,629 - 102,934,174 (+)NCBICelera
RGSC_v3.113108,169,967 - 108,175,623 (+)NCBI
Cytogenetic Map13q27NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-bromohexadecanoic acid  (ISO)
2-methoxyethanol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole  (ISO)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
aldosterone  (EXP)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (EXP)
AM-251  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (EXP,ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
cannabidiol  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
curcumin  (ISO)
D-glucose  (EXP)
D-penicillamine  (EXP)
deguelin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP)
dicoumarol  (ISO)
dicrotophos  (ISO)
Didecyldimethylammonium  (ISO)
dimethyl sulfoxide  (ISO)
disulfiram  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elesclomol  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
flurotyl  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
gardiquimod  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
gentamycin  (EXP)
glucose  (EXP)
GSK-J4  (ISO)
irinotecan  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
mercury atom  (EXP)
mercury dibromide  (ISO)
mercury dichloride  (EXP)
mercury(0)  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
motexafin gadolinium  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP,ISO)
N-acetyl-L-cysteine  (ISO)
nefazodone  (EXP)
nickel dichloride  (EXP)
nitroprusside  (ISO)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentetic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phorone  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propanal  (ISO)
protein kinase inhibitor  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
sodium arsenite  (ISO)
spironolactone  (EXP)
staurosporine  (ISO)
sulfasalazine  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zidovudine  (ISO)
zinc acetate  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP,ISO)
zinc oxide  (ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Zinc transporter-1: a novel NMDA receptor-binding protein at the postsynaptic density. Mellone M, etal., J Neurochem. 2015 Jan;132(2):159-68. doi: 10.1111/jnc.12968. Epub 2015 Jan 4.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Silencing of ZnT-1 expression enhances heavy metal influx and toxicity. Ohana E, etal., J Mol Med (Berl). 2006 Sep;84(9):753-63. Epub 2006 Jun 2.
6. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. Palmiter RD and Findley SD, EMBO J 1995 Feb 15;14(4):639-49.
7. Silencing of ZnT1 reduces Zn2+ efflux in cultured cortical neurons. Qin Y, etal., Neurosci Lett. 2009 Jan 30;450(2):206-10. doi: 10.1016/j.neulet.2008.11.069. Epub 2008 Dec 10.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. ZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger. Shusterman E, etal., Metallomics. 2014 Sep;6(9):1656-63. doi: 10.1039/c4mt00108g.
11. Zinc transport and the inhibition of the L-type calcium channel are two separable functions of ZnT-1. Shusterman E, etal., Metallomics. 2017 Mar 22;9(3):228-238. doi: 10.1039/c6mt00296j.
12. Zinc transporter-1 concentrates at the postsynaptic density of hippocampal synapses. Sindreu C, etal., Mol Brain. 2014 Mar 7;7:16. doi: 10.1186/1756-6606-7-16.
13. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:9560190   PMID:15378655   PMID:15451416   PMID:15452870   PMID:15867272   PMID:17196651   PMID:17349999   PMID:18158319   PMID:18289514   PMID:19059322   PMID:19767393   PMID:20167268  
PMID:20201890   PMID:20838921   PMID:21775119   PMID:24807795   PMID:26463958  


Genomics

Comparative Map Data
Slc30a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813106,022,019 - 106,025,892 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl13106,022,019 - 106,025,892 (+)EnsemblGRCr8
mRatBN7.213103,491,037 - 103,494,910 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,491,037 - 103,494,910 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13106,010,977 - 106,014,850 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013107,394,814 - 107,398,687 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013104,609,816 - 104,613,689 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013110,677,810 - 110,681,683 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,677,810 - 110,681,683 (+)Ensemblrn6Rnor6.0
Rnor_5.013115,236,547 - 115,240,420 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413107,980,864 - 107,986,519 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera13102,913,629 - 102,934,174 (+)NCBICelera
RGSC_v3.113108,169,967 - 108,175,623 (+)NCBI
Cytogenetic Map13q27NCBI
SLC30A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381211,571,568 - 211,579,161 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1211,571,568 - 211,579,161 (-)Ensemblhg38GRCh38
GRCh371211,744,910 - 211,752,503 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361209,815,004 - 209,818,722 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341208,136,777 - 208,140,494NCBI
Celera1184,975,478 - 184,979,196 (-)NCBICelera
Cytogenetic Map1q32.3NCBI
HuRef1182,425,777 - 182,429,495 (-)NCBIHuRef
CHM1_11213,020,769 - 213,024,487 (-)NCBICHM1_1
T2T-CHM13v2.01210,817,650 - 210,825,243 (-)NCBIT2T-CHM13v2.0
Slc30a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,638,810 - 191,645,359 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1191,638,879 - 191,645,359 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381191,906,697 - 191,913,248 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,906,767 - 191,913,247 (+)Ensemblmm10GRCm38
MGSCv371193,730,660 - 193,737,126 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361193,607,396 - 193,613,862 (+)NCBIMGSCv36mm8
Celera1198,856,473 - 198,862,938 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.01NCBI
Slc30a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554065,639,341 - 5,668,331 (+)Ensembl
ChiLan1.0NW_0049554065,662,312 - 5,668,331 (+)NCBIChiLan1.0ChiLan1.0
SLC30A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2137,823,879 - 37,831,549 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1137,789,091 - 37,796,722 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01187,139,544 - 187,147,113 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11192,002,503 - 192,009,515 (-)NCBIPanPan1.1PanPan1.1panPan2
SLC30A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.179,952,373 - 9,959,382 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl79,955,877 - 9,959,388 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha79,530,323 - 9,537,455 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.079,658,190 - 9,665,320 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl79,659,293 - 9,665,282 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.179,581,103 - 9,588,235 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.079,683,054 - 9,690,180 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.079,807,567 - 9,814,703 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc30a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934464,548,981 - 64,555,903 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365571,789,263 - 1,796,541 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365571,789,263 - 1,796,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC30A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9131,633,585 - 131,640,672 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19131,633,586 - 131,636,934 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29144,671,051 - 144,677,621 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC30A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12517,926,656 - 17,933,805 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2517,926,078 - 17,933,783 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605518,450,966 - 18,458,625 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc30a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477117,262,866 - 17,270,340 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477117,262,933 - 17,269,795 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Slc30a1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11070,000,887 - 70,007,392 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Slc30a1
21 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:399
Count of miRNA genes:234
Interacting mature miRNAs:280
Transcripts:ENSRNOT00000006340
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006340   ⟹   ENSRNOP00000006340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl13106,022,019 - 106,025,892 (+)Ensembl
mRatBN7.2 Ensembl13103,491,037 - 103,494,910 (+)Ensembl
Rnor_6.0 Ensembl13110,677,810 - 110,681,683 (+)Ensembl
RefSeq Acc Id: NM_022853   ⟹   NP_074044
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813106,022,019 - 106,025,892 (+)NCBI
mRatBN7.213103,491,037 - 103,494,910 (+)NCBI
Rnor_6.013110,677,810 - 110,681,683 (+)NCBI
Rnor_5.013115,236,547 - 115,240,420 (+)NCBI
RGSC_v3.413107,980,864 - 107,986,519 (+)RGD
Celera13102,913,629 - 102,934,174 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_074044 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA79234 (Get FASTA)   NCBI Sequence Viewer  
  EDL95011 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006340
  ENSRNOP00000006340.2
GenBank Protein Q62720 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_074044   ⟸   NM_022853
- UniProtKB: Q62720 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006340   ⟸   ENSRNOT00000006340
Protein Domains
Cation efflux protein cytoplasmic

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62720-F1-model_v2 AlphaFold Q62720 1-507 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699122
Promoter ID:EPDNEW_R9647
Type:initiation region
Name:Slc30a1_1
Description:solute carrier family 30 member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013110,677,796 - 110,677,856EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61918 AgrOrtholog
BioCyc Gene G2FUF-16823 BioCyc
Ensembl Genes ENSRNOG00000004749 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000006340 ENTREZGENE
  ENSRNOT00000006340.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1510.10 UniProtKB/Swiss-Prot
InterPro Cation_efflux UniProtKB/Swiss-Prot
  Cation_efflux_CTD_sf UniProtKB/Swiss-Prot
  Cation_efflux_TMD_sf UniProtKB/Swiss-Prot
KEGG Report rno:58976 UniProtKB/Swiss-Prot
NCBI Gene 58976 ENTREZGENE
PANTHER FI23527P1 UniProtKB/Swiss-Prot
  ZINC TRANSPORTER 1 UniProtKB/Swiss-Prot
Pfam Cation_efflux UniProtKB/Swiss-Prot
PhenoGen Slc30a1 PhenoGen
RatGTEx ENSRNOG00000004749 RatGTEx
Superfamily-SCOP SSF160240 UniProtKB/Swiss-Prot
  SSF161111 UniProtKB/Swiss-Prot
TIGR TC211502
UniProt A6JH05_RAT UniProtKB/TrEMBL
  Q62720 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc30a1  solute carrier family 30 member 1  Slc30a1  solute carrier family 30 (zinc transporter), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc30a1  solute carrier family 30 (zinc transporter), member 1    solute carrier family 30, member 1   Name updated 1299863 APPROVED
2002-06-10 Slc30a1  solute carrier family 30, member 1       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to plasma membrane 61756
gene_domains predicted protein contains 6 membrane-spanning domains, large intracellular loop, and a C-terminal tail 61756
gene_mutations_overexpression cells with mutant phenotype have higher steady-state level of intracellular zinc 61756