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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61918
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc30a1
Name: solute carrier family 30 member 1
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc30a1affects response to substanceISOSLC30A1 (Homo sapiens)6480464CTDSLC30A1 gene mutant form affects the susceptibility to Arsenic TrioxidePMID:30815697
Slc30a1increases expressionISOSLC30A1 (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of SLC30A1 mRNA; Arsenic Trioxide results in increased expression of SLC30A1 proteinPMID:26705709 PMID:27829220 PMID:30093655
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