SLC30A1 (solute carrier family 30 member 1) - Rat Genome Database

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Gene: SLC30A1 (solute carrier family 30 member 1) Canis lupus familiaris
Analyze
Symbol: SLC30A1
Name: solute carrier family 30 member 1
RGD ID: 12228244
Description: ENCODES a protein that exhibits zinc ion transmembrane transporter activity (ortholog); zinc:proton antiporter activity (ortholog); INVOLVED IN cadmium ion transmembrane transport (ortholog); calcium ion import (ortholog); detoxification of cadmium ion (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); parathyroid carcinoma (ortholog); FOUND IN dendrite (ortholog); glutamatergic postsynaptic density (ortholog); postsynaptic density membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: solute carrier family 30 (zinc transporter), member 1; zinc transporter 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.179,952,373 - 9,959,382 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl79,955,877 - 9,959,388 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha79,530,323 - 9,537,455 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.079,658,190 - 9,665,320 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl79,659,293 - 9,665,282 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.179,581,103 - 9,588,235 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.079,683,054 - 9,690,180 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.079,807,567 - 9,814,703 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:19130129   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC30A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.179,952,373 - 9,959,382 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl79,955,877 - 9,959,388 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha79,530,323 - 9,537,455 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.079,658,190 - 9,665,320 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl79,659,293 - 9,665,282 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.179,581,103 - 9,588,235 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.079,683,054 - 9,690,180 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.079,807,567 - 9,814,703 (-)NCBIUU_Cfam_GSD_1.0
SLC30A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381211,571,568 - 211,579,161 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1211,571,568 - 211,579,161 (-)EnsemblGRCh38hg38GRCh38
GRCh371211,744,910 - 211,752,503 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361209,815,004 - 209,818,722 (-)NCBINCBI36Build 36hg18NCBI36
Build 341208,136,777 - 208,140,494NCBI
Celera1184,975,478 - 184,979,196 (-)NCBICelera
Cytogenetic Map1q32.3NCBI
HuRef1182,425,777 - 182,429,495 (-)NCBIHuRef
CHM1_11213,020,769 - 213,024,487 (-)NCBICHM1_1
T2T-CHM13v2.01210,817,650 - 210,825,243 (-)NCBIT2T-CHM13v2.0
Slc30a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,638,810 - 191,645,359 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1191,638,879 - 191,645,359 (+)EnsemblGRCm39 Ensembl
GRCm381191,906,697 - 191,913,248 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,906,767 - 191,913,247 (+)EnsemblGRCm38mm10GRCm38
MGSCv371193,730,660 - 193,737,126 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361193,607,396 - 193,613,862 (+)NCBIMGSCv36mm8
Celera1198,856,473 - 198,862,938 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.01NCBI
Slc30a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813106,022,019 - 106,025,892 (+)NCBIGRCr8
mRatBN7.213103,491,037 - 103,494,910 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,491,037 - 103,494,910 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13106,010,977 - 106,014,850 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013107,394,814 - 107,398,687 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013104,609,816 - 104,613,689 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013110,677,810 - 110,681,683 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,677,810 - 110,681,683 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013115,236,547 - 115,240,420 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413107,980,864 - 107,986,519 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113108,169,967 - 108,175,623 (+)NCBI
Celera13102,913,629 - 102,934,174 (+)NCBICelera
Cytogenetic Map13q27NCBI
Slc30a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554065,639,341 - 5,668,331 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554065,662,312 - 5,668,331 (+)NCBIChiLan1.0ChiLan1.0
SLC30A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2137,823,879 - 37,831,549 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1137,789,091 - 37,796,722 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01187,139,544 - 187,147,113 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11192,002,503 - 192,009,515 (-)NCBIpanpan1.1PanPan1.1panPan2
Slc30a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934464,548,981 - 64,555,903 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365571,789,263 - 1,796,541 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365571,789,263 - 1,796,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC30A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9131,633,585 - 131,640,672 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19131,633,586 - 131,636,934 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29144,671,051 - 144,677,621 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC30A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12517,926,656 - 17,933,805 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2517,926,078 - 17,933,783 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605518,450,966 - 18,458,625 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc30a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477117,262,866 - 17,270,340 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477117,262,933 - 17,269,795 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC30A1
50 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 21 6 2 6 6 12 8 10
Low 4 5 1 4 6 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000046849   ⟹   ENSCAFP00000041421
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl79,955,877 - 9,959,388 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845005953   ⟹   ENSCAFP00845004737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl79,659,293 - 9,665,282 (-)Ensembl
RefSeq Acc Id: XM_003434930   ⟹   XP_003434978
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.179,952,373 - 9,959,382 (-)NCBI
Dog10K_Boxer_Tasha79,530,323 - 9,537,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038480750   ⟹   XP_038336678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.179,581,103 - 9,588,235 (-)NCBI
RefSeq Acc Id: XM_038542070   ⟹   XP_038397998
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.079,807,567 - 9,814,703 (-)NCBI
RefSeq Acc Id: XM_038606229   ⟹   XP_038462157
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.079,683,054 - 9,690,180 (-)NCBI
RefSeq Acc Id: XM_038670922   ⟹   XP_038526850
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.079,658,190 - 9,665,320 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003434978   ⟸   XM_003434930
- UniProtKB: A0A8C0KH51 (UniProtKB/TrEMBL),   A0A8C0NB42 (UniProtKB/TrEMBL),   A0A8I3MQV1 (UniProtKB/TrEMBL),   C1IPW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000041421   ⟸   ENSCAFT00000046849
RefSeq Acc Id: XP_038336678   ⟸   XM_038480750
RefSeq Acc Id: XP_038462157   ⟸   XM_038606229
RefSeq Acc Id: XP_038526850   ⟸   XM_038670922
- UniProtKB: A0A8C0KH51 (UniProtKB/TrEMBL),   A0A8C0NB42 (UniProtKB/TrEMBL),   A0A8I3MQV1 (UniProtKB/TrEMBL),   C1IPW3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038397998   ⟸   XM_038542070
- UniProtKB: A0A8C0KH51 (UniProtKB/TrEMBL),   A0A8C0NB42 (UniProtKB/TrEMBL),   A0A8I3MQV1 (UniProtKB/TrEMBL),   C1IPW3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845004737   ⟸   ENSCAFT00845005953


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031999 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030014243 UniProtKB/TrEMBL
  ENSCAFG00040018709 UniProtKB/TrEMBL
  ENSCAFG00845003355 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000046849.3 UniProtKB/TrEMBL
  ENSCAFT00030026345.1 UniProtKB/TrEMBL
  ENSCAFT00040034594.1 UniProtKB/TrEMBL
  ENSCAFT00845005953 ENTREZGENE
  ENSCAFT00845005953.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1510.10 UniProtKB/TrEMBL
InterPro Cation_efflux UniProtKB/TrEMBL
  Cation_efflux_CTD_sf UniProtKB/TrEMBL
  Cation_efflux_TMD_sf UniProtKB/TrEMBL
NCBI Gene SLC30A1 ENTREZGENE
PANTHER FI23527P1 UniProtKB/TrEMBL
  ZINC TRANSPORTER 1 UniProtKB/TrEMBL
Pfam Cation_efflux UniProtKB/TrEMBL
Superfamily-SCOP SSF160240 UniProtKB/TrEMBL
  SSF161111 UniProtKB/TrEMBL
UniProt A0A8C0KH51 ENTREZGENE
  A0A8C0NB42 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MQV1 ENTREZGENE, UniProtKB/TrEMBL
  C1IPW3 ENTREZGENE, UniProtKB/TrEMBL
  F2Y8J7_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46346 ENTREZGENE