GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc30a1 | affects expression | EXP | | 6480464 | CTD | Zinc affects the expression of SLC30A1 mRNA | PMID:15867272 | Slc30a1 | affects localization | EXP | | 6480464 | CTD | Zinc affects the localization of SLC30A1 protein | PMID:21636019 | Slc30a1 | affects transport | EXP | | 6480464 | CTD | SLC30A1 protein affects the transport of Zinc | PMID:21775119 | Slc30a1 | decreases expression | EXP | | 6480464 | CTD | Zinc deficiency results in decreased expression of SLC30A1 protein | PMID:12421840 | Slc30a1 | decreases response to substance | EXP | | 6480464 | CTD | SLC30A1 mRNA results in decreased susceptibility to Zinc; SLC30A1 protein results in decreased susceptibility to Zinc; SLC30A1 results in decreased susceptibility to Zinc | PMID:15378655 PMID:7882967 PMID:9254680 | Slc30a1 | increases expression | EXP | | 6480464 | CTD | Zinc results in increased expression of SLC30A1 mRNA; Zinc results in increased expression of SLC30A1 protein | PMID:15378655 PMID:21636019 PMID:9254680 | Slc30a1 | multiple interactions | EXP | | 6480464 | CTD | Pentetic Acid affects the reaction [SLC30A1 protein affects the transport of Zinc]; SLC30A1 protein inhibits the reaction [SLC30A1 gene mutant form results in increased susceptibility to Zinc]; SLC30A1 protein promotes the reaction [[MT1 protein co-treated with MT2 protein] inhibits the reaction [SLC30A1 gene mutant form results in increased susceptibility to Zinc]] | PMID:15041749 PMID:21775119 | Slc30a1 | decreases expression | ISO | Slc30a1 (Mus musculus) | 6480464 | CTD | Zinc deficiency results in decreased expression of SLC30A1; Zinc deficiency results in decreased expression of SLC30A1 protein | PMID:18936201 PMID:19492079 | Slc30a1 | decreases expression | ISO | SLC30A1 (Homo sapiens) | 6480464 | CTD | Zinc deficiency results in decreased expression of SLC30A1 mRNA; Zinc results in decreased expression of SLC30A1 mRNA; Zinc results in decreased expression of SLC30A1 protein | PMID:15753530 PMID:19720134 PMID:22171008 | Slc30a1 | decreases uptake | ISO | Slc30a1 (Mus musculus) | 6480464 | CTD | SLC30A1 protein results in decreased uptake of Zinc | PMID:19288494 | Slc30a1 | increases expression | ISO | Slc30a1 (Mus musculus) | 6480464 | CTD | Zinc results in increased expression of SLC30A1; Zinc results in increased expression of SLC30A1 mRNA | PMID:19288494 PMID:20133611 | Slc30a1 | increases expression | ISO | SLC30A1 (Homo sapiens) | 6480464 | CTD | Zinc results in increased expression of SLC30A1 mRNA; Zinc results in increased expression of SLC30A1 protein | PMID:14568174 PMID:15226459 PMID:15276077 PMID:15867382 PMID:16434472 PMID:17473989 PMID:17622302 PMID:20479680 | Slc30a1 | increases transport | ISO | SLC30A1 (Homo sapiens) | 6480464 | CTD | SLC30A1 protein results in increased transport of Zinc | PMID:18326752 | Slc30a1 | increases uptake | ISO | SLC30A1 (Homo sapiens) | 6480464 | CTD | SLC30A1 protein results in increased uptake of Zinc | PMID:18615482 | Slc30a1 | multiple interactions | ISO | Slc30a1 (Mus musculus) | 6480464 | CTD | [MT1 protein co-treated with MT2 protein] inhibits the reaction [SLC30A1 gene mutant form results in increased susceptibility to Zinc]; [MT1 protein co-treated with MT2 protein] promotes the reaction [SLC30A1 protein inhibits the reaction [SLC30A1 gene mutant form results in increased susceptibility to Zinc]]; SLC30A1 inhibits the reaction [Zinc results in increased expression of and results in increased secretion of CLU protein] | PMID:15041749 PMID:19288494 | Slc30a1 | multiple interactions | ISO | SLC30A1 (Homo sapiens) | 6480464 | CTD | [PCI 5002 co-treated with Zinc] results in increased expression of SLC30A1 mRNA; [Zinc co-treated with motexafin gadolinium] results in increased expression of SLC30A1 mRNA; [Zinc co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of SLC30A1 mRNA; Zinc inhibits the reaction [ochratoxin A promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC30A1 mRNA]]; Zinc results in increased expression of and affects the localization of SLC30A1 protein | PMID:15867382 PMID:18593933 PMID:19720134 PMID:19900532 | |
Go Back to source page | Continue to Ontology report |