RT1-A2 (RT1 class Ia, locus A2) - Rat Genome Database

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Pathways
Gene: RT1-A2 (RT1 class Ia, locus A2) Rattus norvegicus
Analyze
Symbol: RT1-A2
Name: RT1 class Ia, locus A2
RGD ID: 1595923
Description: Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class I. Predicted to be located in lumenal side of endoplasmic reticulum membrane and phagocytic vesicle membrane. Predicted to be part of MHC class I protein complex. Human ortholog(s) of this gene implicated in several diseases, including arthritis (multiple); asthma (multiple); eye disease (multiple); inner ear disease (multiple); and vasculitis (multiple). Orthologous to several human genes including HLA-H (major histocompatibility complex, class I, H (pseudogene)); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC95123; RT1 class I gene (A-2); RT1 class Ia, A2n; RT1 class Ia, locus A2 (mapped); RT1-A2_mapped; RT1-A2n; RT1.A2(N); RT1A-2
RGD Orthologs
Human
Mouse
Bonobo
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,872,720 - 4,876,425 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2204,870,939 - 4,910,183 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.0205,374,990 - 5,378,536 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,374,985 - 5,378,539 (+)Ensemblrn6Rnor6.0
Rnor_5.0207,433,437 - 7,436,984 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4205,021,816 - 5,025,341 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera206,470,599 - 6,474,124 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrobenzenesulfonic acid  (ISO)
2,6-dinitrotoluene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-phenylbutyric acid  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aconitine  (EXP)
all-trans-retinoic acid  (ISO)
ammonium acetate  (EXP)
ammonium chloride  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cefuroxime  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
ciprofloxacin  (ISO)
clindamycin  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
corosolic acid  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
etoposide  (ISO)
famotidine  (ISO)
ferric oxide  (ISO)
ferroheme b  (ISO)
fumonisin B1  (ISO)
gentamycin  (EXP)
heme b  (ISO)
hydrochlorothiazide  (ISO)
inulin  (ISO)
isotretinoin  (ISO)
ketorolac  (ISO)
lincomycin  (ISO)
malathion  (ISO)
menadione  (ISO)
methidathion  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
mifepristone  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (EXP)
nitrates  (ISO)
ochratoxin A  (ISO)
ofloxacin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
progesterone  (ISO)
quercitrin  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thalidomide  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
tolmetin  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (EXP)
troglitazone  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (ISO)
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent  (IBA)
antigen processing and presentation of endogenous peptide antigen via MHC class Ib  (IBA,ISO)
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent  (ISO)
antigen processing and presentation of exogenous peptide antigen via MHC class Ib  (ISO)
antigen processing and presentation of peptide antigen via MHC class I  (IEA)
CD8-positive, alpha-beta T cell activation  (ISO)
immune response  (IBA)
immune system process  (IEA)
inner ear development  (ISO)
natural killer cell tolerance induction  (ISO)
negative regulation of natural killer cell activation  (ISO)
negative regulation of natural killer cell mediated cytotoxicity  (ISO)
negative regulation of T cell proliferation  (ISO)
positive regulation of antibody-dependent cellular cytotoxicity  (ISO)
positive regulation of CD8-positive, alpha-beta T cell activation  (ISO)
positive regulation of CD8-positive, alpha-beta T cell proliferation  (ISO)
positive regulation of immunoglobulin production  (ISO)
positive regulation of interleukin-13 production  (ISO)
positive regulation of interleukin-4 production  (ISO)
positive regulation of natural killer cell activation  (ISO)
positive regulation of natural killer cell cytokine production  (ISO)
positive regulation of natural killer cell mediated cytotoxicity  (ISO)
positive regulation of natural killer cell mediated immunity  (ISO)
positive regulation of natural killer cell proliferation  (ISO)
positive regulation of T cell mediated cytotoxicity  (IBA,ISO)
positive regulation of TRAIL production  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
protection from natural killer cell mediated cytotoxicity  (ISO)
regulation of natural killer cell mediated immunity  (ISO)
signal transduction  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. A novel instance of class I modification (cim) affecting two of three rat class I RT1-A molecules within one MHC haplotype. Gonzalez-Munoz AL, etal., J Immunol. 2003 Jul 1;171(1):274-84.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1538753   PMID:9427624   PMID:9443915   PMID:9486650   PMID:9754572   PMID:10799855   PMID:11685465   PMID:12411439   PMID:12477932   PMID:12763482   PMID:12902470   PMID:14735325  
PMID:16474394   PMID:17179229   PMID:18083576   PMID:18339401   PMID:18448674   PMID:19666135   PMID:20018625   PMID:22562814   PMID:23100519   PMID:23335510   PMID:25631937   PMID:28676677  
PMID:29531166   PMID:30087334   PMID:30134159  


Genomics

Comparative Map Data
RT1-A2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,872,720 - 4,876,425 (+)NCBIGRCr8GRCr8GRCr8
mRatBN7.2204,870,939 - 4,910,183 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.0205,374,990 - 5,378,536 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,374,985 - 5,378,539 (+)Ensemblrn6Rnor6.0
Rnor_5.0207,433,437 - 7,436,984 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4205,021,816 - 5,025,341 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera206,470,599 - 6,474,124 (+)NCBICelera
Cytogenetic Map20p12NCBI
HLA-E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38630,489,509 - 30,494,194 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl630,489,503 - 30,494,205 (+)Ensemblhg38GRCh38
GRCh37630,457,286 - 30,461,971 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36630,565,250 - 30,569,077 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34630,565,287 - 30,568,337NCBI
Celera632,055,310 - 32,060,109 (+)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef630,257,312 - 30,262,111 (+)NCBIHuRef
CHM1_1630,459,288 - 30,464,087 (+)NCBICHM1_1
T2T-CHM13v2.0630,353,696 - 30,358,381 (+)NCBIT2T-CHM13v2.0
H2-T23
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391736,340,869 - 36,343,593 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1736,340,665 - 36,343,747 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381736,029,977 - 36,032,701 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1736,029,773 - 36,032,855 (-)Ensemblmm10GRCm38
MGSCv371736,166,922 - 36,169,646 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361735,638,030 - 35,640,754 (-)NCBIMGSCv36mm8
Celera1739,547,532 - 39,600,702 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.86NCBI
LOC100977055
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2545,048,829 - 45,053,645 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1641,011,935 - 41,016,698 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0630,233,293 - 30,238,056 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1631,104,186 - 31,108,978 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl631,101,251 - 31,107,262 (+)EnsemblpanPan2panpan1.1

Variants

.
Variants in RT1-A2
574 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:168
Count of miRNA genes:75
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000038660, ENSRNOT00000052270
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015332005306452Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2016693431Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
7175096Tcs1T cell selection QTL 1T cell selection trait (VT:0004917)expression2047282825026446Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2016693431Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362632310078622Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036263239244918Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001008829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC088465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX883042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG963096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000038660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,375,650 - 5,377,440 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000052270   ⟹   ENSRNOP00000050701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,374,985 - 5,378,539 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082497   ⟹   ENSRNOP00000073153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,555,782 - 3,559,486 (-)Ensembl
RefSeq Acc Id: NM_001008829   ⟹   NP_001008829
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,872,871 - 4,876,422 (+)NCBI
mRatBN7.2204,870,986 - 4,874,537 (+)NCBI
Rnor_6.0205,375,011 - 5,378,536 (+)NCBI
Rnor_5.0207,433,437 - 7,436,984 (+)NCBI
RGSC_v3.4205,021,816 - 5,025,341 (+)RGD
Celera206,470,599 - 6,474,124 (+)RGD
Sequence:
RefSeq Acc Id: XM_017601545   ⟹   XP_017457034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,872,829 - 4,876,425 (+)NCBI
mRatBN7.2204,870,945 - 4,874,540 (+)NCBI
Rnor_6.0205,374,990 - 5,378,535 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063278965   ⟹   XP_063135035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,872,840 - 4,876,425 (+)NCBI
RefSeq Acc Id: XM_063278966   ⟹   XP_063135036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,872,830 - 4,876,425 (+)NCBI
RefSeq Acc Id: XM_063278967   ⟹   XP_063135037
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,872,720 - 4,876,425 (+)NCBI
RefSeq Acc Id: XM_063278968   ⟹   XP_063135038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,872,832 - 4,876,425 (+)NCBI
RefSeq Acc Id: XM_063278969   ⟹   XP_063135039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8204,872,832 - 4,876,425 (+)NCBI
RefSeq Acc Id: NP_001008829   ⟸   NM_001008829
- Peptide Label: precursor
- UniProtKB: Q6MGB8 (UniProtKB/TrEMBL),   F7ERG5 (UniProtKB/TrEMBL),   P79602 (UniProtKB/TrEMBL),   Q95569 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457034   ⟸   XM_017601545
- Peptide Label: isoform X6
- UniProtKB: P79602 (UniProtKB/TrEMBL),   Q95569 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000050701   ⟸   ENSRNOT00000052270
Ensembl Acc Id: ENSRNOP00000073153   ⟸   ENSRNOT00000082497
RefSeq Acc Id: XP_063135037   ⟸   XM_063278967
- Peptide Label: isoform X3
- UniProtKB: P79602 (UniProtKB/TrEMBL),   Q95569 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135036   ⟸   XM_063278966
- Peptide Label: isoform X2
- UniProtKB: P79602 (UniProtKB/TrEMBL),   Q95569 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135039   ⟸   XM_063278969
- Peptide Label: isoform X5
- UniProtKB: P79602 (UniProtKB/TrEMBL),   Q95569 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135038   ⟸   XM_063278968
- Peptide Label: isoform X4
- UniProtKB: P79602 (UniProtKB/TrEMBL),   Q95569 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135035   ⟸   XM_063278965
- Peptide Label: isoform X1
- UniProtKB: P79602 (UniProtKB/TrEMBL),   Q95569 (UniProtKB/TrEMBL)
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6MGB8-F1-model_v2 AlphaFold Q6MGB8 1-366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701406
Promoter ID:EPDNEW_R11930
Type:single initiation site
Name:RT1-A2_1
Description:RT1 class Ia, locus A2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0205,374,985 - 5,375,045EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595923 AgrOrtholog
BioCyc Gene G2FUF-4526 BioCyc
Ensembl Genes ENSRNOG00000030712 Ensembl
  ENSRNOG00000069480 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061027 ENTREZGENE
  ENSRNOT00000061027.8 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.30.500.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7127909 IMAGE-MGC_LOAD
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/TrEMBL
  MHC_class-I_related UniProtKB/TrEMBL
  MHC_I-like_Ag-recog UniProtKB/TrEMBL
  MHC_I-like_Ag-recog_sf UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  MHC_I_a_a1/a2 UniProtKB/TrEMBL
  MHC_I_a_C UniProtKB/TrEMBL
KEGG Report rno:24974 UniProtKB/TrEMBL
MGC_CLONE MGC:95123 IMAGE-MGC_LOAD
NCBI Gene 24974 ENTREZGENE
PANTHER HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN UniProtKB/TrEMBL
  MHC CLASS I-RELATED UniProtKB/TrEMBL
Pfam C1-set UniProtKB/TrEMBL
  MHC_I UniProtKB/TrEMBL
  MHC_I_C UniProtKB/TrEMBL
PhenoGen RT1-A2 PhenoGen
PRINTS MHCCLASSI UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  IG_MHC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030712 RatGTEx
  ENSRNOG00000069480 RatGTEx
SMART IGc1 UniProtKB/TrEMBL
Superfamily-SCOP MHC_I/II-like_Ag-recog UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt E9PTZ7_RAT UniProtKB/TrEMBL
  F7ERG5 ENTREZGENE
  P79602 ENTREZGENE, UniProtKB/TrEMBL
  Q6MGB8 ENTREZGENE, UniProtKB/TrEMBL
  Q95569 ENTREZGENE
UniProt Secondary F7ERG5 UniProtKB/TrEMBL
  Q95569 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2007-04-12 RT1-A2  RT1 class Ia, locus A2  RT1-A2_mapped  RT1 class Ia, locus A2 (mapped)  Data merged from RGD:3466 737654 APPROVED
2006-11-20 RT1-A2_mapped  RT1 class Ia, locus A2(mapped)  RT1-A2  RT1 class Ia, locus A2  Symbol set to symbol_mapped, name set to name (mapped) 1582166 APPROVED
2006-11-20 RT1-A2  RT1 class Ia, locus A2      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-13 RT1-A2  RT1 class Ia, locus A2  RT1A-2  RT1 class I gene (A-2)  Data merged from RGD:3510 737654 APPROVED
2002-06-10 RT1-A2  RT1 class Ia, locus A2      Symbol and Name status set to approved 70586 APPROVED