Pard6b (par-6 family cell polarity regulator beta) - Rat Genome Database

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Gene: Pard6b (par-6 family cell polarity regulator beta) Rattus norvegicus
Analyze
Symbol: Pard6b
Name: par-6 family cell polarity regulator beta
RGD ID: 1308205
Description: Predicted to be involved in several processes, including centrosome cycle; establishment or maintenance of cell polarity; and protein-containing complex assembly. Part of protein-containing complex. Orthologous to human PARD6B (par-6 family cell polarity regulator beta); PARTICIPATES IN protein kinase C (PKC) signaling pathway; endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362279; par-6 (partitioning defective 6) homolog beta; par-6 (partitioning defective 6) homolog beta (C. elegans); partitioning defective 6 homolog beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83177,209,429 - 177,230,509 (+)NCBIGRCr8
mRatBN7.23156,790,540 - 156,811,620 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3160,585,351 - 160,606,433 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03169,084,429 - 169,105,513 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03166,826,135 - 166,847,217 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03164,822,111 - 164,843,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03170,968,975 - 170,990,259 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,230,673 - 159,251,755 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13159,136,214 - 159,157,286 (+)NCBI
Celera3155,366,567 - 155,386,818 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
amphotericin B  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
dibutyl phthalate  (EXP)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
indole-3-methanol  (EXP)
ivermectin  (ISO)
leflunomide  (ISO)
levonorgestrel  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
N-nitrosodiethylamine  (EXP)
ochratoxin A  (ISO)
ozone  (ISO)
paracetamol  (EXP)
pentachlorophenol  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
potassium dichromate  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
testosterone undecanoate  (ISO)
thioacetamide  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. The PAR-aPKC system: lessons in polarity. Suzuki A and Ohno S, J Cell Sci. 2006 Mar 15;119(Pt 6):979-87.
7. Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis. Wong EW, etal., Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9657-62. Epub 2008 Jul 10.
Additional References at PubMed
PMID:12545177   PMID:15950600   PMID:19056867   PMID:19620967   PMID:22333836  


Genomics

Comparative Map Data
Pard6b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83177,209,429 - 177,230,509 (+)NCBIGRCr8
mRatBN7.23156,790,540 - 156,811,620 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3160,585,351 - 160,606,433 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03169,084,429 - 169,105,513 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03166,826,135 - 166,847,217 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03164,822,111 - 164,843,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03170,968,975 - 170,990,259 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,230,673 - 159,251,755 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13159,136,214 - 159,157,286 (+)NCBI
Celera3155,366,567 - 155,386,818 (+)NCBICelera
Cytogenetic Map3q42NCBI
PARD6B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382050,731,580 - 50,753,741 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2050,731,580 - 50,756,795 (+)EnsemblGRCh38hg38GRCh38
GRCh372049,348,117 - 49,370,278 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362048,781,488 - 48,803,685 (+)NCBINCBI36Build 36hg18NCBI36
Build 342048,781,730 - 48,800,432NCBI
Celera2046,052,360 - 46,074,607 (+)NCBICelera
Cytogenetic Map20q13.13NCBI
HuRef2046,096,474 - 46,118,701 (+)NCBIHuRef
CHM1_12049,253,147 - 49,275,696 (+)NCBICHM1_1
T2T-CHM13v2.02052,501,886 - 52,524,081 (+)NCBIT2T-CHM13v2.0
Pard6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392167,922,924 - 167,943,123 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2167,922,924 - 167,943,123 (+)EnsemblGRCm39 Ensembl
GRCm382168,081,004 - 168,101,203 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2168,081,004 - 168,101,203 (+)EnsemblGRCm38mm10GRCm38
MGSCv372167,906,504 - 167,926,703 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362167,772,490 - 167,790,415 (+)NCBIMGSCv36mm8
Celera2174,023,444 - 174,043,724 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map288.24NCBI
Pard6b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554457,625,303 - 7,638,654 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554457,625,303 - 7,638,652 (-)NCBIChiLan1.0ChiLan1.0
PARD6B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22156,480,187 - 56,502,616 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12056,473,355 - 56,495,732 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02047,076,007 - 47,098,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12048,203,994 - 48,223,814 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2048,203,900 - 48,229,376 (+)Ensemblpanpan1.1panPan2
PARD6B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12437,108,441 - 37,122,118 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2436,349,345 - 36,365,076 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02437,816,193 - 37,832,591 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2437,816,255 - 37,832,600 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12437,052,429 - 37,068,151 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02437,186,155 - 37,201,876 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02437,730,480 - 37,746,871 (+)NCBIUU_Cfam_GSD_1.0
Pard6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640188,500,105 - 188,519,486 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365143,953,753 - 3,966,312 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365143,953,748 - 3,967,871 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARD6B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1752,195,041 - 52,213,843 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11752,195,360 - 52,211,504 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21758,650,703 - 58,651,538 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21758,583,393 - 58,588,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PARD6B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1213,218,514 - 13,239,206 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl213,215,929 - 13,237,421 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605061,648,766 - 61,668,024 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pard6b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247904,939,592 - 4,960,531 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247904,939,753 - 4,960,432 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pard6b
98 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:479
Count of miRNA genes:257
Interacting mature miRNAs:311
Transcripts:ENSRNOT00000014568
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat

Markers in Region
RH136841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23156,811,291 - 156,811,423 (+)MAPPERmRatBN7.2
Rnor_6.03164,843,067 - 164,843,198NCBIRnor6.0
Rnor_5.03170,989,931 - 170,990,062UniSTSRnor5.0
RGSC_v3.43159,251,427 - 159,251,558UniSTSRGSC3.4
Celera3155,386,490 - 155,386,621UniSTS
RH 3.4 Map31480.7UniSTS
Cytogenetic Map3q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 10 2 2 2 14 35 19 11
Low 2 33 55 39 19 39 8 8 60 22 8
Below cutoff 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000014568   ⟹   ENSRNOP00000014568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)Ensembl
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)Ensembl
RefSeq Acc Id: NM_001108609   ⟹   NP_001102079
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83177,209,429 - 177,230,509 (+)NCBI
mRatBN7.23156,790,540 - 156,811,620 (+)NCBI
Rnor_6.03164,822,111 - 164,843,395 (+)NCBI
Rnor_5.03170,968,975 - 170,990,259 (+)NCBI
RGSC_v3.43159,230,673 - 159,251,755 (+)RGD
Celera3155,366,567 - 155,386,818 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102079 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96380 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014568
  ENSRNOP00000014568.4
Reference Protein Sequences
RefSeq Acc Id: NP_001102079   ⟸   NM_001108609
- UniProtKB: D4A2F2 (UniProtKB/TrEMBL),   A6JXM9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014568   ⟸   ENSRNOT00000014568
Protein Domains
PB1   PDZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A2F2-F1-model_v2 AlphaFold D4A2F2 1-372 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692696
Promoter ID:EPDNEW_R3221
Type:single initiation site
Name:Pard6b_1
Description:par-6 family cell polarity regulator beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03164,822,172 - 164,822,232EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308205 AgrOrtholog
BioCyc Gene G2FUF-46711 BioCyc
Ensembl Genes ENSRNOG00000010883 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014568 ENTREZGENE
  ENSRNOT00000014568.5 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro OPR_PB1 UniProtKB/TrEMBL
  PB1_Par6 UniProtKB/TrEMBL
  PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
KEGG Report rno:362279 UniProtKB/TrEMBL
NCBI Gene 362279 ENTREZGENE
PANTHER PAR-6-RELATED UniProtKB/TrEMBL
  PTHR14102:SF4 UniProtKB/TrEMBL
Pfam PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PhenoGen Pard6b PhenoGen
PROSITE PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010883 RatGTEx
SMART PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP CAD & PB1 domains UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
UniProt A6JXM9 ENTREZGENE, UniProtKB/TrEMBL
  D4A2F2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-19 Pard6b  par-6 family cell polarity regulator beta  Pard6b  par-6 (partitioning defective 6) homolog beta (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pard6b  par-6 (partitioning defective 6) homolog beta (C. elegans)   Pard6b_predicted  par-6 (partitioning defective 6) homolog beta (C. elegans) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pard6b_predicted  par-6 (partitioning defective 6) homolog beta (C. elegans) (predicted)      Symbol and Name status set to approved 70820 APPROVED