PARD6B (par-6 family cell polarity regulator beta) - Rat Genome Database

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Gene: PARD6B (par-6 family cell polarity regulator beta) Canis lupus familiaris
Analyze
Symbol: PARD6B
Name: par-6 family cell polarity regulator beta
RGD ID: 12140017
Description: INVOLVED IN cell division (inferred); centrosome cycle (inferred); establishment or maintenance of cell polarity (inferred); PARTICIPATES IN protein kinase C (PKC) signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: par-6 partitioning defective 6 homolog beta; partitioning defective 6 homolog beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12437,108,441 - 37,122,118 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2436,349,345 - 36,365,076 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02437,816,193 - 37,832,591 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2437,816,255 - 37,832,600 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12437,052,429 - 37,068,151 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02437,186,155 - 37,201,876 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02437,730,480 - 37,746,871 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:23439680   PMID:30032202  


Genomics

Comparative Map Data
PARD6B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12437,108,441 - 37,122,118 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2436,349,345 - 36,365,076 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02437,816,193 - 37,832,591 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2437,816,255 - 37,832,600 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12437,052,429 - 37,068,151 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02437,186,155 - 37,201,876 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02437,730,480 - 37,746,871 (+)NCBIUU_Cfam_GSD_1.0
PARD6B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382050,731,580 - 50,753,741 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2050,731,580 - 50,756,795 (+)EnsemblGRCh38hg38GRCh38
GRCh372049,348,117 - 49,370,278 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362048,781,488 - 48,803,685 (+)NCBINCBI36Build 36hg18NCBI36
Build 342048,781,730 - 48,800,432NCBI
Celera2046,052,360 - 46,074,607 (+)NCBICelera
Cytogenetic Map20q13.13NCBI
HuRef2046,096,474 - 46,118,701 (+)NCBIHuRef
CHM1_12049,253,147 - 49,275,696 (+)NCBICHM1_1
T2T-CHM13v2.02052,501,886 - 52,524,081 (+)NCBIT2T-CHM13v2.0
Pard6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392167,922,924 - 167,943,123 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2167,922,924 - 167,943,123 (+)EnsemblGRCm39 Ensembl
GRCm382168,081,004 - 168,101,203 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2168,081,004 - 168,101,203 (+)EnsemblGRCm38mm10GRCm38
MGSCv372167,906,504 - 167,926,703 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362167,772,490 - 167,790,415 (+)NCBIMGSCv36mm8
Celera2174,023,444 - 174,043,724 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map288.24NCBI
Pard6b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83177,209,429 - 177,230,509 (+)NCBIGRCr8
mRatBN7.23156,790,540 - 156,811,620 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3160,585,351 - 160,606,433 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03169,084,429 - 169,105,513 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03166,826,135 - 166,847,217 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03164,822,111 - 164,843,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03170,968,975 - 170,990,259 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,230,673 - 159,251,755 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13159,136,214 - 159,157,286 (+)NCBI
Celera3155,366,567 - 155,386,818 (+)NCBICelera
Cytogenetic Map3q42NCBI
Pard6b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554457,625,303 - 7,638,654 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554457,625,303 - 7,638,652 (-)NCBIChiLan1.0ChiLan1.0
PARD6B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22156,480,187 - 56,502,616 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12056,473,355 - 56,495,732 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02047,076,007 - 47,098,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12048,203,994 - 48,223,814 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2048,203,900 - 48,229,376 (+)Ensemblpanpan1.1panPan2
Pard6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640188,500,105 - 188,519,486 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365143,953,753 - 3,966,312 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365143,953,748 - 3,967,871 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARD6B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1752,195,041 - 52,213,843 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11752,195,360 - 52,211,504 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21758,650,703 - 58,651,538 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21758,583,393 - 58,588,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PARD6B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1213,218,514 - 13,239,206 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl213,215,929 - 13,237,421 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605061,648,766 - 61,668,024 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pard6b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247904,939,592 - 4,960,531 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247904,939,753 - 4,960,432 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PARD6B
142 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00845046921   ⟹   ENSCAFP00845036805
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2437,816,255 - 37,832,600 (+)Ensembl
RefSeq Acc Id: XM_038434091   ⟹   XP_038290019
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02437,816,193 - 37,832,591 (+)NCBI
RefSeq Acc Id: XM_038457963   ⟹   XP_038313891
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2436,349,345 - 36,365,076 (+)NCBI
RefSeq Acc Id: XM_038509264   ⟹   XP_038365192
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12437,052,429 - 37,068,151 (+)NCBI
RefSeq Acc Id: XM_038572595   ⟹   XP_038428523
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02437,730,480 - 37,746,871 (+)NCBI
RefSeq Acc Id: XM_038636873   ⟹   XP_038492801
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02437,186,155 - 37,201,876 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038365192   ⟸   XM_038509264
RefSeq Acc Id: XP_038492801   ⟸   XM_038636873
RefSeq Acc Id: XP_038290019   ⟸   XM_038434091
- UniProtKB: A0A8C0PHC2 (UniProtKB/TrEMBL),   A0A8C0KYK6 (UniProtKB/TrEMBL),   A0A8I3PSX6 (UniProtKB/TrEMBL),   A0A8C0PCJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313891   ⟸   XM_038457963
- UniProtKB: A0A8C0PHC2 (UniProtKB/TrEMBL),   A0A8C0KYK6 (UniProtKB/TrEMBL),   A0A8I3PSX6 (UniProtKB/TrEMBL),   A0A8C0PCJ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428523   ⟸   XM_038572595
- UniProtKB: A0A8C0KYK6 (UniProtKB/TrEMBL),   A0A8C0PCJ7 (UniProtKB/TrEMBL),   A0A8C0PHC2 (UniProtKB/TrEMBL),   A0A8I3PSX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845036805   ⟸   ENSCAFT00845046921
Protein Domains
PB1   PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000056693 UniProtKB/TrEMBL
  ENSCAFG00030024322 UniProtKB/TrEMBL
  ENSCAFG00040011828 UniProtKB/TrEMBL
  ENSCAFG00845026631 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000096081.1 UniProtKB/TrEMBL
  ENSCAFT00030044721.1 UniProtKB/TrEMBL
  ENSCAFT00030044740.1 UniProtKB/TrEMBL
  ENSCAFT00040021785.1 UniProtKB/TrEMBL
  ENSCAFT00040021811.1 UniProtKB/TrEMBL
  ENSCAFT00845046921 ENTREZGENE
  ENSCAFT00845046921.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro PB1_dom UniProtKB/TrEMBL
  PB1_Par6 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
NCBI Gene PARD6B ENTREZGENE
PANTHER PAR-6-RELATED UniProtKB/TrEMBL
  PTHR14102:SF4 UniProtKB/TrEMBL
Pfam PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PROSITE PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP CAD & PB1 domains UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt A0A8C0KYK6 ENTREZGENE
  A0A8C0PCJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PHC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PSX6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:54725 ENTREZGENE