Cacng8 (calcium voltage-gated channel auxiliary subunit gamma 8) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cacng8 (calcium voltage-gated channel auxiliary subunit gamma 8) Rattus norvegicus
Analyze
Symbol: Cacng8
Name: calcium voltage-gated channel auxiliary subunit gamma 8
RGD ID: 628808
Description: Enables ionotropic glutamate receptor binding activity and protein phosphatase 2B binding activity. Involved in positive regulation of AMPA receptor activity. Located in dendrite membrane and postsynaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human CACNG8 (calcium voltage-gated channel auxiliary subunit gamma 8); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: calcium channel, voltage-dependent, gamma subunit 8; neuronal voltage-gated calcium channel gamma-8 subunit; TARP gamma-8; transmembrane AMPAR regulatory protein gamma-8; voltage-dependent calcium channel gamma-8 subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8174,670,767 - 74,691,003 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl174,669,766 - 74,694,015 (-)EnsemblGRCr8
mRatBN7.2165,755,334 - 65,775,567 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,755,334 - 65,779,089 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx171,203,496 - 71,223,728 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0179,626,484 - 79,646,716 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0172,959,544 - 72,979,828 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd174,150,528 - 74,170,760 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive178,113,533 - 78,133,753 (-)NCBILyon_Normotensive
Lyon_Hypertensive175,829,538 - 75,849,759 (-)NCBILyon_Hypertensive
F344_StmMcwi172,967,224 - 72,987,456 (-)NCBIF344_StmMcwi
Rnor_6.0164,330,106 - 64,350,338 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl164,330,106 - 64,350,338 (-)Ensemblrn6Rnor6.0
Rnor_5.0163,321,710 - 63,341,943 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4164,068,324 - 64,088,556 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera163,480,060 - 63,499,712 (-)NCBICelera
RGSC_v3.1164,145,070 - 64,165,304 (-)NCBI
Cytogenetic Map1q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Calcium channel gamma subunits provide insights into the evolution of this gene family. Chu PJ, etal., Gene 2001 Dec 12;280(1-2):37-48.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Direct association of the unique C-terminal tail of transmembrane AMPA receptor regulatory protein gamma-8 with calcineurin. Itakura M, etal., FEBS J. 2014 Mar;281(5):1366-78. doi: 10.1111/febs.12708. Epub 2014 Jan 27.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating. Milstein AD, etal., Neuron. 2007 Sep 20;55(6):905-18.
7. Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction. Ortega A, etal., PLoS One. 2015 Dec 28;10(12):e0145518. doi: 10.1371/journal.pone.0145518. eCollection 2015.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors. Schwenk J, etal., Science. 2009 Mar 6;323(5919):1313-9. doi: 10.1126/science.1167852.
12. Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5. Soto D, etal., Nat Neurosci. 2009 Mar;12(3):277-85. doi: 10.1038/nn.2266. Epub 2009 Feb 22.
13. Functional studies and distribution define a family of transmembrane AMPA receptor regulatory proteins. Tomita S, etal., J Cell Biol. 2003 May 26;161(4):805-16. doi: 10.1083/jcb.200212116.
14. Dynamic interaction of stargazin-like TARPs with cycling AMPA receptors at synapses. Tomita S, etal., Science 2004 Mar 5;303(5663):1508-11.
Additional References at PubMed
PMID:17074043   PMID:20805473   PMID:21127204   PMID:21172611   PMID:22871113   PMID:25495042   PMID:25931508   PMID:26725511   PMID:27076426   PMID:29490264   PMID:30872532   PMID:35136046  


Genomics

Comparative Map Data
Cacng8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8174,670,767 - 74,691,003 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl174,669,766 - 74,694,015 (-)EnsemblGRCr8
mRatBN7.2165,755,334 - 65,775,567 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,755,334 - 65,779,089 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx171,203,496 - 71,223,728 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0179,626,484 - 79,646,716 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0172,959,544 - 72,979,828 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd174,150,528 - 74,170,760 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive178,113,533 - 78,133,753 (-)NCBILyon_Normotensive
Lyon_Hypertensive175,829,538 - 75,849,759 (-)NCBILyon_Hypertensive
F344_StmMcwi172,967,224 - 72,987,456 (-)NCBIF344_StmMcwi
Rnor_6.0164,330,106 - 64,350,338 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl164,330,106 - 64,350,338 (-)Ensemblrn6Rnor6.0
Rnor_5.0163,321,710 - 63,341,943 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4164,068,324 - 64,088,556 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera163,480,060 - 63,499,712 (-)NCBICelera
RGSC_v3.1164,145,070 - 64,165,304 (-)NCBI
Cytogenetic Map1q12NCBI
CACNG8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381953,962,937 - 53,990,215 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1953,962,937 - 53,990,215 (+)Ensemblhg38GRCh38
GRCh371954,466,191 - 54,493,469 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361959,158,106 - 59,177,951 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341959,158,105 - 59,177,951NCBI
Celera1951,505,965 - 51,525,810 (+)NCBICelera
Cytogenetic Map19q13.42NCBI
HuRef1950,783,089 - 50,809,780 (+)NCBIHuRef
CHM1_11954,468,073 - 54,495,260 (+)NCBICHM1_1
T2T-CHM13v2.01957,041,427 - 57,068,705 (+)NCBIT2T-CHM13v2.0
Cacng8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3973,442,558 - 3,464,782 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl73,439,199 - 3,464,164 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3873,394,042 - 3,416,266 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl73,390,683 - 3,415,648 (+)Ensemblmm10GRCm38
MGSCv3773,394,459 - 3,415,366 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera73,346,589 - 3,368,017 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map71.98NCBI
Cacng8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955604204,482 - 221,833 (-)NCBIChiLan1.0ChiLan1.0
CACNG8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22059,970,553 - 59,996,884 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11961,892,343 - 61,918,671 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01950,899,256 - 50,920,028 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11959,745,315 - 59,772,864 (+)NCBIPanPan1.1PanPan1.1panPan2
CACNG8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11103,245,102 - 103,263,154 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1103,250,132 - 103,263,178 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1103,311,932 - 103,324,845 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01103,900,218 - 103,913,136 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1103,900,218 - 103,913,241 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11103,532,913 - 103,545,825 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01103,294,645 - 103,307,574 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01104,013,588 - 104,026,528 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cacng8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093492,778,679 - 2,802,840 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936994146,550 - 159,122 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNG8
(Sus scrofa - pig)		 No map positions available.
CACNG8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1646,649,793 - 46,670,918 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl646,649,865 - 46,670,452 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607326,727,009 - 26,748,041 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cacng8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248322,505,057 - 2,517,886 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cacng8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12178,028,343 - 178,050,397 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cacng8
82 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:58
Count of miRNA genes:55
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000019300
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat

Markers in Region
RH140816  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2165,757,856 - 65,757,980 (+)MAPPERmRatBN7.2
Rnor_6.0164,332,630 - 64,332,753NCBIRnor6.0
Rnor_5.0163,324,235 - 63,324,358UniSTSRnor5.0
RGSC_v3.4164,070,848 - 64,070,971UniSTSRGSC3.4
Celera163,481,996 - 63,482,119UniSTS
RH 3.4 Map1740.8UniSTS
Cytogenetic Map1q12UniSTS
BE102334  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2165,774,891 - 65,775,067 (+)MAPPERmRatBN7.2
Rnor_6.0164,349,663 - 64,349,838NCBIRnor6.0
Rnor_5.0163,341,268 - 63,341,443UniSTSRnor5.0
RGSC_v3.4164,087,881 - 64,088,056UniSTSRGSC3.4
Celera163,499,037 - 63,499,212UniSTS
RH 3.4 Map1741.5UniSTS
Cytogenetic Map1q12UniSTS
ECD23507  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2165,755,909 - 65,756,097 (+)MAPPERmRatBN7.2
Rnor_6.0164,330,682 - 64,330,869NCBIRnor6.0
Rnor_5.0163,322,286 - 63,322,473UniSTSRnor5.0
RGSC_v3.4164,068,900 - 64,069,087UniSTSRGSC3.4
Cytogenetic Map1q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
6 6 27 121 50 43 25 39 25 6 155 86 103 34 61 18 8 8

Sequence


Ensembl Acc Id: ENSRNOT00000078444   ⟹   ENSRNOP00000075354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl174,669,766 - 74,694,015 (-)Ensembl
mRatBN7.2 Ensembl165,755,334 - 65,779,089 (-)Ensembl
Rnor_6.0 Ensembl164,330,106 - 64,350,338 (-)Ensembl
RefSeq Acc Id: NM_080696   ⟹   NP_542427
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8174,670,767 - 74,691,003 (-)NCBI
mRatBN7.2165,755,334 - 65,775,567 (-)NCBI
Dahl_SR_JrHsd174,150,528 - 74,170,760 (-)NCBI
Lyon_Normotensive178,113,533 - 78,133,753 (-)NCBI
Lyon_Hypertensive175,829,538 - 75,849,759 (-)NCBI
F344_StmMcwi172,967,224 - 72,987,456 (-)NCBI
Rnor_6.0164,330,106 - 64,350,338 (-)NCBI
Rnor_5.0163,321,710 - 63,341,943 (-)NCBI
RGSC_v3.4164,068,324 - 64,088,556 (-)RGD
Celera163,480,060 - 63,499,712 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_542427 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL50041 (Get FASTA)   NCBI Sequence Viewer  
  EDL84945 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075354
GenBank Protein Q8VHW5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_542427   ⟸   NM_080696
- UniProtKB: Q8VHW5 (UniProtKB/Swiss-Prot),   F1M7K7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075354   ⟸   ENSRNOT00000078444

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VHW5-F1-model_v2 AlphaFold Q8VHW5 1-421 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628808 AgrOrtholog
BioCyc Gene G2FUF-61025 BioCyc
Ensembl Genes ENSRNOG00000057848 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000078444 ENTREZGENE
Gene3D-CATH 1.20.140.150 UniProtKB/Swiss-Prot
InterPro CACNG_subunit UniProtKB/Swiss-Prot
  PMP22/EMP/MP20/Claudin UniProtKB/Swiss-Prot
  VDCC_g8su UniProtKB/Swiss-Prot
  VDCC_gsu UniProtKB/Swiss-Prot
KEGG Report rno:140729 UniProtKB/Swiss-Prot
NCBI Gene 140729 ENTREZGENE
PANTHER VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT UniProtKB/Swiss-Prot
  VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-8 SUBUNIT UniProtKB/Swiss-Prot
Pfam PMP22_Claudin UniProtKB/Swiss-Prot
PhenoGen Cacng8 PhenoGen
PRINTS VDCCGAMMA UniProtKB/Swiss-Prot
  VDCCGAMMA8 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000057848 RatGTEx
UniProt A6KS38_RAT UniProtKB/TrEMBL
  CCG8_RAT UniProtKB/Swiss-Prot
  F1M7K7 ENTREZGENE, UniProtKB/TrEMBL
  Q8VHW5 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Cacng8  calcium voltage-gated channel auxiliary subunit gamma 8  Cacng8  calcium channel, voltage-dependent, gamma subunit 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Cacng8  calcium channel, voltage-dependent, gamma subunit 8    voltage-dependent calcium channel gamma-8 subunit  Name updated 1299863 APPROVED
2003-02-27 Cacng8  voltage-dependent calcium channel gamma-8 subunit      Symbol and Name status set to provisional 70820 PROVISIONAL