Gene: Ppp3ca (protein phosphatase 3, catalytic subunit, alpha isozyme)  Rattus norvegicus

Symbol: Ppp3ca
Name: protein phosphatase 3, catalytic subunit, alpha isozyme
Description: ENCODES a protein that exhibits calcium-dependent protein serine/threonine phosphatase activity; calmodulin binding; phosphoprotein phosphatase activity; INVOLVED IN cellular response to glucose stimulus; negative regulation of insulin secretion; protein dephosphorylation; PARTICIPATES IN calcineurin signaling pathway; interleukin-12 signaling pathway; Alzheimer disease pathway; ASSOCIATED WITH cardiac hypertrophy; ASSOCIATED WITH Brain Injuries; Hypertrophy, Right Ventricular; Reperfusion Injury; FOUND IN calcineurin complex; cytosol; membrane; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: calcineurin subunit A alpha; Calcineurin subunit A alpha; calmodulin-dependent calcineurin A subunit alpha isoform; Calna1; CAM-PRP catalytic subunit; protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; protein phosphatase 3, catalytic subunit, alpha isoform; protein phosphatase-2Ba; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Orthologs: Homo sapiens : PPP3CA (protein phosphatase 3, catalytic subunit, alpha isozyme)  HGNC
Mus musculus : Ppp3ca (protein phosphatase 3, catalytic subunit, alpha isoform)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map2q43 NCBI
RGSC Genome Assembly v5.02260,463,274 - 260,735,296+NCBI
RGSC Genome Assembly v3.42234,130,176 - 234,409,232+NCBI
Rat Celera Assembly2217,359,756 - 217,630,340+NCBI
Genome Assembly 3.12234,116,915 - 234,395,972+NCBI
Model

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ppp3ca
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RGD Object Information
RGD ID: 3382
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2013-04-30
Status: ACTIVE