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Gene: Polr2e (RNA polymerase II, I and III subunit E) Rattus norvegicus

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Symbol:

Polr2e

Name:

RNA polymerase II, I and III subunit E

RGD ID:

1589817

Description:

Predicted to enable DNA binding activity. Predicted to contribute to DNA-directed RNA polymerase activity. Predicted to be involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase II; and transcription elongation by RNA polymerase I. Predicted to be located in nucleus. Predicted to be part of RPAP3/R2TP/prefoldin-like complex and nuclear DNA-directed RNA polymerase complex. Orthologous to human POLR2E (RNA polymerase II, I and III subunit E); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription pathway; RNA polymerase III transcription pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

DNA-directed RNA polymerase II subunit E; DNA-directed RNA polymerases I, II, and III subunit RPABC1; LOC690966; polymerase (RNA) II (DNA directed) polypeptide E; polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; polymerase (RNA) II subunit E; RNA polymerase II subunit E; RNA polymerases I, II, and III subunit ABC1; RPB5; RPB5 homolog; similar to DNA-directed RNA polymerase II 23 kDa polypeptide (RPB25) (RPB5) (RPABC1)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	POLR2E (RNA polymerase II, I and III subunit E)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Polr2e (polymerase (RNA) II (DNA directed) polypeptide E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Polr2e (RNA polymerase II, I and III subunit E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	POLR2E (RNA polymerase II, I and III subunit E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	POLR2E (RNA polymerase II, I and III subunit E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Polr2e (RNA polymerase II, I and III subunit E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	POLR2E (RNA polymerase II, I and III subunit E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	POLR2E (RNA polymerase II, I and III subunit E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Polr2e (RNA polymerase II, I and III subunit E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Polr2e (RNA polymerase II, I and III subunit E)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	POLR2E (RNA polymerase II, I and III subunit E)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Polr2e (polymerase (RNA) II (DNA directed) polypeptide E)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	polr2ea (polymerase (RNA) II (DNA directed) polypeptide E, a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	polr2eb (polymerase (RNA) II (DNA directed) polypeptide E, b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rpb-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RPB5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Rpb5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	polr2e	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	polr2e	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,317,332 - 10,321,280 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	10,317,389 - 10,321,276 (+)	Ensembl				GRCr8
mRatBN7.2	7	9,666,695 - 9,670,638 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,666,716 - 9,670,643 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	12,549,536 - 12,553,410 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,424,874 - 14,428,748 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,285,994 - 12,289,868 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,532,785 - 12,536,797 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,532,895 - 12,536,791 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	12,702,927 - 12,706,900 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	11,179,283 - 11,183,205 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	7,842,509 - 7,846,431 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Dwarfism (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

1-nitropyrene (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP)

2-hydroxypropanoic acid (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

butanal (ISO)

carmustine (ISO)

chlorpyrifos (ISO)

choline (ISO)

chromium(6+) (ISO)

cobalt dichloride (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

deguelin (ISO)

deoxynivalenol (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dioxygen (ISO)

epoxiconazole (ISO)

folic acid (ISO)

ivermectin (ISO)

L-methionine (ISO)

nitrates (ISO)

oxaliplatin (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

rotenone (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

T-2 toxin (ISO)

tert-butyl hydroperoxide (ISO)

thiram (ISO)

triphenyl phosphate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

DNA-templated transcription (IEA)

termination of RNA polymerase III transcription (IEA,ISO)

transcription by RNA polymerase II (IBA,IEA,ISO,ISS)

transcription by RNA polymerase III (IEA,ISO)

transcription elongation by RNA polymerase I (IBA,IEA,ISO)

transcription elongation by RNA polymerase II (IEA,ISO)

transcription initiation at RNA polymerase II promoter (IEA,ISO)

transcription initiation at RNA polymerase III promoter (IEA,ISO)

tRNA transcription by RNA polymerase III (IBA)

Cellular Component

DNA-directed RNA polymerase complex (IEA)

nucleolus (IEA)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO,ISS)

RNA polymerase I complex (IBA,IEA,ISO)

RNA polymerase II, core complex (IBA,IEA,ISO,ISS)

RNA polymerase III complex (IBA,IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-directed RNA polymerase activity (IBA,IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Huntington's disease pathway (IEA)

purine metabolic pathway (IEA)

pyrimidine metabolic pathway (IEA)

RNA polymerase I transcription pathway (ISO)

RNA polymerase II transcription pathway (ISO)

RNA polymerase III transcription pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription.	Dumay-Odelot H, etal., Cell Cycle. 2010 Sep 15;9(18):3687-99. Epub 2010 Sep 1.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits.	Hu P, etal., Mol Cell Biol. 2002 Nov;22(22):8044-55.
4.	TFIIB-related factors in RNA polymerase I transcription.	Knutson BA and Hahn S, Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):265-73. doi: 10.1016/j.bbagrm.2012.08.003. Epub 2012 Aug 30.
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Comprehensive gene review and curation	RGD comprehensive gene curation
8.	RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.	Schneider DA Gene. 2012 Feb 10;493(2):176-84. doi: 10.1016/j.gene.2011.08.006. Epub 2011 Aug 26.
9.	Conservation between the RNA polymerase I, II, and III transcription initiation machineries.	Vannini A and Cramer P, Mol Cell. 2012 Feb 24;45(4):439-46. doi: 10.1016/j.molcel.2012.01.023.

Additional References at PubMed

PMID:9268387	PMID:9852112	PMID:12477932

Genomics

Comparative Map Data

Polr2e
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,317,332 - 10,321,280 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	10,317,389 - 10,321,276 (+)	Ensembl				GRCr8
mRatBN7.2	7	9,666,695 - 9,670,638 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,666,716 - 9,670,643 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	12,549,536 - 12,553,410 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,424,874 - 14,428,748 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,285,994 - 12,289,868 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,532,785 - 12,536,797 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,532,895 - 12,536,791 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	12,702,927 - 12,706,900 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	11,179,283 - 11,183,205 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	7,842,509 - 7,846,431 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

POLR2E
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	1,086,574 - 1,095,375 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	1,085,104 - 1,095,389 (-)	Ensembl			hg38	GRCh38
GRCh37	19	1,086,573 - 1,095,374 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	1,039,163 - 1,046,336 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	1,039,165 - 1,046,336	NCBI
Celera	19	1,019,553 - 1,028,363 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	860,059 - 868,869 (-)	NCBI		HuRef
CHM1_1	19	1,086,181 - 1,094,986 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	1,051,240 - 1,060,040 (-)	NCBI		T2T-CHM13v2.0

Polr2e
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	79,871,787 - 79,875,493 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	79,871,783 - 79,875,629 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	80,035,953 - 80,039,659 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	80,035,949 - 80,039,795 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	79,498,698 - 79,502,404 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	79,439,639 - 79,442,869 (-)	NCBI		MGSCv36	mm8
Celera	10	81,050,761 - 81,054,467 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Polr2e
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	6,778,993 - 6,790,725 (+)	Ensembl
ChiLan1.0	NW_004955495	6,779,557 - 6,788,241 (+)	NCBI	ChiLan1.0	ChiLan1.0

POLR2E
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	5,421,085 - 5,438,308 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	4,658,825 - 4,674,825 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	32,263 - 41,992 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	1,063,296 - 1,073,379 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	1,065,421 - 1,073,379 (-)	Ensembl			panPan2	panpan1.1

POLR2E
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	57,649,836 - 57,653,661 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	57,649,868 - 57,654,199 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	57,452,042 - 57,455,856 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	58,391,944 - 58,395,762 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	58,392,009 - 58,395,762 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	57,447,255 - 57,451,066 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	57,926,783 - 57,930,597 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	58,129,830 - 58,133,647 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Polr2e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	217,335,308 - 217,340,338 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	494,399 - 499,952 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	494,445 - 499,659 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

POLR2E
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	77,330,686 - 77,341,900 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	77,330,755 - 77,341,910 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	77,655,741 - 77,666,891 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

POLR2E
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	844,196 - 856,127 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	841,615 - 855,214 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666081	8,003,368 - 8,013,758 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Polr2e
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	7,547,460 - 7,553,282 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624828	7,547,401 - 7,553,282 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Polr2e
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	154,835,613 - 154,839,266 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Polr2e
165 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	201
Count of miRNA genes:	139
Interacting mature miRNAs:	146
Transcripts:	ENSRNOT00000018169
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1669658	46669658	Rat
1300176	Hrtrt10	Heart rate QTL 10	3.19		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	1	23748937	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	7216097	52216097	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	10112916	99900612	Rat
2290372	Gluco33	Glucose level QTL 33	2.71		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	1	31777942	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1709527	46709527	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	32612984	Rat
1582260	Bw72	Body weight QTL 72	3.2	0.0043	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
1582261	Bw69	Body weight QTL 69	3.2	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
1582262	Bw75	Body weight QTL 75	3	0.0038	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	10112916	60150541	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	9460877	54460877	Rat
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	29716167	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	34650782	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	32612984	Rat

Markers in Region

RH127647

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	9,670,334 - 9,670,546 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	12,536,494 - 12,536,705	NCBI	Rnor6.0
Rnor_5.0	7	12,706,597 - 12,706,808	UniSTS	Rnor5.0
RGSC_v3.4	7	11,182,902 - 11,183,113	UniSTS	RGSC3.4
Celera	7	7,846,128 - 7,846,339	UniSTS
RH 3.4 Map	7	25.6	UniSTS
Cytogenetic Map	7	q11	UniSTS

RH130774

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	9,667,001 - 9,667,191 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	12,533,161 - 12,533,350	NCBI	Rnor6.0
Rnor_5.0	7	12,703,264 - 12,703,453	UniSTS	Rnor5.0
RGSC_v3.4	7	11,179,569 - 11,179,758	UniSTS	RGSC3.4
Celera	7	7,842,795 - 7,842,984	UniSTS
RH 3.4 Map	7	25.6	UniSTS
Cytogenetic Map	7	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079930	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC158787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018169 ⟹ ENSRNOP00000018169

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	10,317,395 - 10,321,272 (+)	Ensembl
mRatBN7.2 Ensembl	7	9,666,716 - 9,670,643 (+)	Ensembl
Rnor_6.0 Ensembl	7	12,532,895 - 12,536,791 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093135 ⟹ ENSRNOP00000076102

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	12,535,527 - 12,536,404 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093413 ⟹ ENSRNOP00000076239

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	10,317,389 - 10,321,276 (+)	Ensembl
mRatBN7.2 Ensembl	7	9,666,742 - 9,670,637 (+)	Ensembl
Rnor_6.0 Ensembl	7	12,532,945 - 12,536,791 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093599 ⟹ ENSRNOP00000076166

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	10,317,415 - 10,321,272 (+)	Ensembl
mRatBN7.2 Ensembl	7	9,666,773 - 9,670,625 (+)	Ensembl
Rnor_6.0 Ensembl	7	12,532,941 - 12,536,791 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093703 ⟹ ENSRNOP00000076293

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	12,536,189 - 12,536,791 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000132392 ⟹ ENSRNOP00000109298

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	10,317,389 - 10,321,276 (+)	Ensembl

RefSeq Acc Id:

NM_001109614 ⟹ NP_001103084

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,317,358 - 10,321,280 (+)	NCBI
mRatBN7.2	7	9,666,716 - 9,670,638 (+)	NCBI
Rnor_6.0	7	12,532,875 - 12,536,797 (+)	NCBI
Rnor_5.0	7	12,702,927 - 12,706,900 (+)	NCBI
RGSC_v3.4	7	11,179,283 - 11,183,205 (+)	RGD
Celera	7	7,842,509 - 7,846,431 (+)	RGD

Sequence:

show sequence

TTATGCTGTCCCGCGCAGGCTCAGTCCTGGTAGGTCTACGAGCGCGCGTGCAGAGTTGTTTGTG
AAGTGCGACAACATGGACGACGAGGAGGAAACGTATCGGCTGTGGAAGATCCGCAAGACTATCA
TGCAGCTGTGTCATGACCGAGGCTACCTGGTGACCCAGGATGAGCTGGACCAGACACTTGAAGA
GTTCAAGGCACAGTTTGGGGACAAGCCCAGCGAAGGACGGCCGAGGCGCACAGACCTCACCGTG
CTGGTGGCCCACAACGATGATCCCACAGACCAGATGTTTGTCTTCTTCCCAGAGGAGCCCAAGG
TGGGCATCAAGACCATCAAGGTGTACTGCCAGCGCATGCAGGAGGAGAACATCACACGGGCGCT
GATCGTGGTGCAGCAGGGCATGACACCCTCCGCCAAGCAGTCCCTGGTAGACATGGCCCCTAAG
TACGTGCTAGAACAGTTTCTACAGCAGGAGCTGCTCATCAATATCACAGAACATGAGCTAGTCC
CTGAGCACGTGGTCATGACCAAGGAGGAGGTGACGGAACTGCTGGCGCGATACAAGCTCCGTGA
GAGCCAGCTGCCCAGGATCCAGGCTGGGGACCCGGTGGCACGGTACTTCGGGATCAAGCGAGGG
CAGGTTGTGAAGATTATCCGCCCCAGTGAGACAGCCGGCCGGTACATCACCTACCGCCTGGTGC
AGTAGCTGCAGGGGAAATCTAGTACTCTGGAGACTGAAGCAGGAGGATTGCTGCAATTGAAGGC
AAGTTTGTGGACTCTTCGGTGTTGGGAGAGTCTCTTCTGGAAAACTGTGGAAAAGAGTCCGCGC
GGCACAGTGCGCAGGGAGACCCCAGGAACCTTCTGCTCTGCCCTTCACAGCTCACCAGCAACCT
CACAGAGGACCAGGCCAGAGCCGCTGCTCCCATGAGCCCCAGCGTGTGGGTCATGGCTTTCATC
CTGCAGGATGAGCAACTTCAGAGCTTCAGCCCCACCCCCACTCCTCGCCCTGAGGTCACTGCTC
TGTTAAGAGTTCTCCATGACTCCCCGGAGAATTAAAAGCTACTTTGGGATAAGTTACT

hide sequence

RefSeq Acc Id:

XM_006241009 ⟹ XP_006241071

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,317,332 - 10,321,010 (+)	NCBI
mRatBN7.2	7	9,666,695 - 9,670,231 (+)	NCBI
Rnor_6.0	7	12,532,785 - 12,536,390 (+)	NCBI
Rnor_5.0	7	12,702,927 - 12,706,900 (+)	NCBI

Sequence:

show sequence

AGTTGGTGTATTCCGGCGATCACCTAAACCAAACCTGGGCGGGGCCTTCTCCGCATTCCGCGCA
GGCGCACTGTGCTGGGGGCGTGCACTTTATGCTGTCCCGCGCAGGCTCAGTCCTGGTAGGTCTA
CGAGCGCGCGTGCAGAGTTGTTTGTGAAGTGCGACAACATGGACGACGAGGAGGAAACGTATCG
GCTGTGGAAGATCCGCAAGACTATCATGCAGCTGTGTCATGACCGAGGCTACCTGGTGACCCAG
GATGAGCTGGACCAGACACTTGAAGAGTTCAAGGCACAGTTTGGGGACAAGCCCAGCGAAGGAC
GGCCGAGGCGCACAGACCTCACCGTGCTGGTGGCCCACAACGATGATCCCACAGACCAGATGTT
TGTCTTCTTCCCAGAGGAGCCCAAGGTGGGCATCAAGACCATCAAGGTGTACTGCCAGCGCATG
CAGGAGGAGAACATCACACGGGCGCTGATCGTGGTGCAGCAGGGCATGACACCCTCCGCCAAGC
AGTCCCTGGTAGACATGGCCCCTAAGTACGTGCTAGAACAGTTTCTACAGCAGGAGCTGCTCAT
CAATATCACAGAACATGAGCTAGTCCCTGAGCACGTGGTCATGACCAAGGAGGAGGTGACGGAA
CTGCTGGCGCGATACAAGCTCCGTGAGAGCCAGCTGCCCAGGATCCAGGCTGGGGACCCGGTGG
CACGGTACTTCGGGATCAAGCGAGGGCAGGTGAGAAGCCATAGCCGTTGTTCCCCTCGCTCTCG
CTCTCTCTCTCTGAAGCCAGCGTCACTATGGCCAGAGGACAGTTGTCCCTCGCCACTGATGCCC
AAGGCCCTGCCACTCCCCGCTCTACCTGCTCCCACAGGTTGTGAAGATTATCCGCCCCAGTGAG
ACAGCCGGCCGGTACATCACCTACCGCCTGGTGCAGTAGCTGCAGGTGAGCCCCAGCAGAATGA
GGGTTTGGTGCTGGATGACCCCGCTGCCTACCCTCGATGCGGTAGAGGGTCTGAGCTGCACCCA
CAAAAATAAAATAACAGAAAGGCAGGCTTGAATCCTAGTGCCCAGGGTGGGTAGAGCCAGGCAG
ATTTCTGAGGTCCAGGCCAGCCAGGGCTACAGAGTAAA

hide sequence

RefSeq Acc Id:

XM_006241010 ⟹ XP_006241072

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,317,421 - 10,321,010 (+)	NCBI
mRatBN7.2	7	9,666,739 - 9,670,231 (+)	NCBI
Rnor_6.0	7	12,532,968 - 12,536,390 (+)	NCBI
Rnor_5.0	7	12,702,927 - 12,706,900 (+)	NCBI

Sequence:

show sequence

AACGTATCGGCTGTGGAAGATCCGCAAGACTATCATGCAGGCGAGTTGCATGGGGAGGTTTTGA
GCGAGCGCTGAGCTGTGGACTAACTGCGGTTGTCTGTCCGCTCAGCCCAGCCTCCAATGGGGGC
TAATCCTCTTGCTTCAGCCTCCCAGCTGTGTCATGACCGAGGCTACCTGGTGACCCAGGATGAG
CTGGACCAGACACTTGAAGAGTTCAAGGCACAGTTTGGGGACAAGCCCAGCGAAGGACGGCCGA
GGCGCACAGACCTCACCGTGCTGGTGGCCCACAACGATGATCCCACAGACCAGATGTTTGTCTT
CTTCCCAGAGGAGCCCAAGGTGGGCATCAAGACCATCAAGGTGTACTGCCAGCGCATGCAGGAG
GAGAACATCACACGGGCGCTGATCGTGGTGCAGCAGGGCATGACACCCTCCGCCAAGCAGTCCC
TGGTAGACATGGCCCCTAAGTACGTGCTAGAACAGTTTCTACAGCAGGAGCTGCTCATCAATAT
CACAGAACATGAGCTAGTCCCTGAGCACGTGGTCATGACCAAGGAGGAGGTGACGGAACTGCTG
GCGCGATACAAGCTCCGTGAGAGCCAGCTGCCCAGGATCCAGGCTGGGGACCCGGTGGCACGGT
ACTTCGGGATCAAGCGAGGGCAGGTGAGAAGCCATAGCCGTTGTTCCCCTCGCTCTCGCTCTCT
CTCTCTGAAGCCAGCGTCACTATGGCCAGAGGACAGTTGTCCCTCGCCACTGATGCCCAAGGCC
CTGCCACTCCCCGCTCTACCTGCTCCCACAGGTTGTGAAGATTATCCGCCCCAGTGAGACAGCC
GGCCGGTACATCACCTACCGCCTGGTGCAGTAGCTGCAGGTGAGCCCCAGCAGAATGAGGGTTT
GGTGCTGGATGACCCCGCTGCCTACCCTCGATGCGGTAGAGGGTCTGAGCTGCACCCACAAAAA
TAAAATAACAGAAAGGCAGGCTTGAATCCTAGTGCCCAGGGTGGGTAGAGCCAGGCAGATTTCT
GAGGTCCAGGCCAGCCAGGGCTACAGAGTAAA

hide sequence

RefSeq Acc Id:

XM_006241011 ⟹ XP_006241073

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,317,385 - 10,321,274 (+)	NCBI
mRatBN7.2	7	9,666,744 - 9,670,636 (+)	NCBI
Rnor_6.0	7	12,532,941 - 12,536,795 (+)	NCBI
Rnor_5.0	7	12,702,927 - 12,706,900 (+)	NCBI

Sequence:

show sequence

GTGCGACAACATGGACGACGAGGAGGAAACGTATCGGCTGTGGAAGATCCGCAAGACTATCATG
CAGGCGAGTTGCATGGGGAGGTTTTGAGCGAGCGCTGAGCTGTGGACTAACTGCGGTTGTCTGT
CCGCTCAGCCCAGCCTCCAATGGGGGCTAATCCTCTTGCTTCAGCCTCCCAGCTGTGTCATGAC
CGAGGCTACCTGGTGACCCAGGATGAGCTGGACCAGACACTTGAAGAGTTCAAGGCACAGTTTG
GGGACAAGCCCAGCGAAGGACGGCCGAGGCGCACAGACCTCACCGTGCTGGTGGCCCACAACGA
TGATCCCACAGACCAGATGTTTGTCTTCTTCCCAGAGGAGCCCAAGGTGGGCATCAAGACCATC
AAGGTGTACTGCCAGCGCATGCAGGAGGAGAACATCACACGGGCGCTGATCGTGGTGCAGCAGG
GCATGACACCCTCCGCCAAGCAGTCCCTGGTAGACATGGCCCCTAAGTACGTGCTAGAACAGTT
TCTACAGCAGGAGCTGCTCATCAATATCACAGAACATGAGCTAGTCCCTGAGCACGTGGTCATG
ACCAAGGAGGAGGTGACGGAACTGCTGGCGCGATACAAGCTCCGTGAGAGCCAGCTGCCCAGGA
TCCAGGCTGGGGACCCGGTGGCACGGTACTTCGGGATCAAGCGAGGGCAGGTTGTGAAGATTAT
CCGCCCCAGTGAGACAGCCGGCCGGTACATCACCTACCGCCTGGTGCAGTAGCTGCAGGGGAAA
TCTAGTACTCTGGAGACTGAAGCAGGAGGATTGCTGCAATTGAAGGCAAGTTTGTGGACTCTTC
GGTGTTGGGAGAGTCTCTTCTGGAAAACTGTGGAAAAGAGTCCGCGCGGCACAGTGCGCAGGGA
GACCCCAGGAACCTTCTGCTCTGCCCTTCACAGCTCACCAGCAACCTCACAGAGGACCAGGCCA
GAGCCGCTGCTCCCATGAGCCCCAGCGTGTGGGTCATGGCTTTCATCCTGCAGGATGAGCAACT
TCAGAGCTTCAGCCCCACCCCCACTCCTCGCCCTGAGGTCACTGCTCTGTTAAGAGTTCTCCAT
GACTCCCCGGAGAATTAAAAGCTACTTTGGGATAAGTTA

hide sequence

RefSeq Acc Id:

XM_039079930 ⟹ XP_038935858

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,317,332 - 10,321,274 (+)	NCBI
mRatBN7.2	7	9,666,695 - 9,670,636 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001103084	(Get FASTA)	NCBI Sequence Viewer
	XP_006241071	(Get FASTA)	NCBI Sequence Viewer
	XP_006241072	(Get FASTA)	NCBI Sequence Viewer
	XP_006241073	(Get FASTA)	NCBI Sequence Viewer
	XP_038935858	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI58788	(Get FASTA)	NCBI Sequence Viewer
	B0BNE2	(Get FASTA)	NCBI Sequence Viewer
	EDL89343	(Get FASTA)	NCBI Sequence Viewer
	EDL89344	(Get FASTA)	NCBI Sequence Viewer
	EDL89345	(Get FASTA)	NCBI Sequence Viewer
	EDL89348	(Get FASTA)	NCBI Sequence Viewer
	EDL89349	(Get FASTA)	NCBI Sequence Viewer
	EDL89350	(Get FASTA)	NCBI Sequence Viewer
	EDL89351	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000076166
	ENSRNOP00000076239
	ENSRNOP00000076239.1

RefSeq Acc Id:

NP_001103084 ⟸ NM_001109614

- UniProtKB:

B0BNE2 (UniProtKB/Swiss-Prot), A6K8S4 (UniProtKB/TrEMBL), A0A1W2Q690 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTVLVAH
NDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYVLE
QFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRESQLPRIQAGDPVARYFGIKRGQVVK
IIRPSETAGRYITYRLVQ

hide sequence

RefSeq Acc Id:	XP_006241071 ⟸ XM_006241009
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2Q9B5 (UniProtKB/TrEMBL), A6K8S6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTVLVAH NDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYVLE QFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRESQLPRIQAGDPVARYFGIKRGQVRS HSRCSPRSRSLSLKPASLWPEDSCPSPLMPKALPLPALPAPTGCEDYPPQ hide sequence

RefSeq Acc Id:	XP_006241073 ⟸ XM_006241011
- Peptide Label:	isoform X4
- UniProtKB:	A0A1W2Q690 (UniProtKB/TrEMBL), A6K8S9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGANPLASASQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTVLVAHNDDPTDQM FVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYVLEQFLQQELL INITEHELVPEHVVMTKEEVTELLARYKLRESQLPRIQAGDPVARYFGIKRGQVVKIIRPSETA GRYITYRLVQ hide sequence

RefSeq Acc Id:

XP_006241072 ⟸ XM_006241010

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGANPLASASQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTVLVAHNDDPTDQM
FVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYVLEQFLQQELL
INITEHELVPEHVVMTKEEVTELLARYKLRESQLPRIQAGDPVARYFGIKRGQVRSHSRCSPRS
RSLSLKPASLWPEDSCPSPLMPKALPLPALPAPTGCEDYPPQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000018169 ⟸ ENSRNOT00000018169

Ensembl Acc Id:

ENSRNOP00000076166 ⟸ ENSRNOT00000093599

Ensembl Acc Id:

ENSRNOP00000076293 ⟸ ENSRNOT00000093703

Ensembl Acc Id:

ENSRNOP00000076239 ⟸ ENSRNOT00000093413

Ensembl Acc Id:

ENSRNOP00000076102 ⟸ ENSRNOT00000093135

RefSeq Acc Id:	XP_038935858 ⟸ XM_039079930
- Peptide Label:	isoform X3
- UniProtKB:	B0BNE2 (UniProtKB/Swiss-Prot), A6K8S4 (UniProtKB/TrEMBL), A0A1W2Q690 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000109298 ⟸ ENSRNOT00000132392

Protein Domains

RNA polymerase Rpb5 N-terminal RNA polymerase subunit H/Rpb5 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B0BNE2-F1-model_v2	AlphaFold	B0BNE2	1-210	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695038

Promoter ID:

EPDNEW_R5563

Type:

initiation region

Name:

Polr2e_1

Description:

RNA polymerase II subunit E

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	12,532,897 - 12,532,957	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1589817	AgrOrtholog
BioCyc Gene	G2FUF-34913	BioCyc
Ensembl Genes	ENSRNOG00000013545	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000093413	ENTREZGENE
	ENSRNOT00000093413.2	UniProtKB/Swiss-Prot
	ENSRNOT00000093599	ENTREZGENE
Gene3D-CATH	3.40.1340.10	UniProtKB/Swiss-Prot
	3.90.940.20	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7304442	IMAGE-MGC_LOAD
InterPro	DNA_RNA_pol_RPB5_euk/virus	UniProtKB/Swiss-Prot
	RNA_pol_Rpb5_N	UniProtKB/Swiss-Prot
	RNA_pol_Rpb5_N_sf	UniProtKB/Swiss-Prot
	RNA_pol_subH/Rpb5_C	UniProtKB/Swiss-Prot
	RNA_pol_subH/Rpb5_CS	UniProtKB/Swiss-Prot
	RPB5-like_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:690966	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:188150	IMAGE-MGC_LOAD
NCBI Gene	690966	ENTREZGENE
PANTHER	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1	UniProtKB/Swiss-Prot
	PTHR10535	UniProtKB/Swiss-Prot
Pfam	RNA_pol_Rpb5_C	UniProtKB/Swiss-Prot
	RNA_pol_Rpb5_N	UniProtKB/Swiss-Prot
PhenoGen	Polr2e	PhenoGen
PIRSF	RPB5	UniProtKB/Swiss-Prot
PROSITE	RNA_POL_H_23KD	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000013545	RatGTEx
Superfamily-SCOP	SSF53036	UniProtKB/Swiss-Prot
	SSF55287	UniProtKB/Swiss-Prot
UniProt	A0A1W2Q690	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2Q9B5	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LET8_RAT	UniProtKB/TrEMBL
	A6K8S4	ENTREZGENE, UniProtKB/TrEMBL
	A6K8S6	ENTREZGENE, UniProtKB/TrEMBL
	A6K8S9	ENTREZGENE, UniProtKB/TrEMBL
	B0BNE2	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-06-22	Polr2e	RNA polymerase II, I and III subunit E	Polr2e	RNA polymerase II subunit E	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-07-21	Polr2e	RNA polymerase II subunit E	Polr2e	polymerase (RNA) II subunit E	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-03-16	Polr2e	polymerase (RNA) II subunit E	Polr2e	polymerase (RNA) II (DNA directed) polypeptide E	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-05-24	Polr2e	polymerase (RNA) II (DNA directed) polypeptide E	LOC687055	similar to DNA-directed RNA polymerase II 23 kDa polypeptide (RPB25) (RPB5) (RPABC1)	Data merged from RGD:1590114	1643240	APPROVED
2009-10-22	Polr2e	polymerase (RNA) II (DNA directed) polypeptide E	Polr2e	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	Polr2e	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	Polr2e	polymerase (RNA) II (DNA directed) polypeptide E	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Polr2e	polymerase (RNA) II (DNA directed) polypeptide E	LOC690966	similar to DNA-directed RNA polymerase II 23 kDa polypeptide (RPB25) (RPB5) (RPABC1)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC690966	similar to DNA-directed RNA polymerase II 23 kDa polypeptide (RPB25) (RPB5) (RPABC1)			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC687055	similar to DNA-directed RNA polymerase II 23 kDa polypeptide (RPB25) (RPB5) (RPABC1)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)