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Gene: Ccnc (cyclin C) Rattus norvegicus

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Symbol:

Ccnc

Name:

cyclin C

RGD ID:

70905

Description:

Contributes to ubiquitin protein ligase activity. Involved in negative regulation of triglyceride metabolic process and protein ubiquitination. Part of ubiquitin ligase complex. Orthologous to human CCNC (cyclin C); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4,6-trinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cyclin-C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CCNC (cyclin C)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Ccnc (cyclin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ccnc (cyclin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CCNC (cyclin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CCNC (cyclin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ccnc (cyclin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CCNC (cyclin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CCNC (cyclin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ccnc (cyclin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ccnc (cyclin C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CCNC (cyclin C)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ccnc (cyclin C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ccnc (cyclin C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CycC	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SSN8	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SSN8	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cic-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ccnc	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	40,063,589 - 40,081,731 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	40,063,623 - 40,093,370 (+)	Ensembl				GRCr8
mRatBN7.2	5	35,266,828 - 35,284,943 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	35,266,823 - 35,296,584 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	37,391,253 - 37,409,196 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	38,983,996 - 39,001,939 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	38,923,510 - 38,941,449 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	35,865,598 - 35,883,732 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	35,865,605 - 35,883,706 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	40,521,947 - 40,540,039 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	36,465,490 - 36,483,538 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	34,283,507 - 34,301,554 (+)	NCBI		Celera
RGSC_v3.1	5	36,465,668 - 36,482,416 (+)	NCBI
Cytogenetic Map	5	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Burns (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-amphetamine (ISO)

1,2-dimethylhydrazine (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,6-trinitrotoluene (EXP)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

5-fluorouracil (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

amphibole asbestos (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

carbon nanotube (ISO)

carbonyl cyanide p-trifluoromethoxyphenylhydrazone (ISO)

chlorpyrifos (ISO)

cobalt atom (ISO)

dexamethasone (ISO)

diallyl disulfide (EXP)

dibutyl phthalate (ISO)

dichlorine (EXP)

dicrotophos (ISO)

dihydroxyacetone (ISO)

dimethylarsinic acid (ISO)

disodium selenite (ISO)

elemental selenium (ISO)

gentamycin (EXP)

indometacin (ISO)

kojic acid (ISO)

L-ascorbic acid (ISO)

lamivudine (ISO)

lidocaine (ISO)

lipopolysaccharide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

metformin (ISO)

methylmercury chloride (ISO)

Monobutylphthalate (EXP)

N-nitrosodiethylamine (ISO)

N-nitrosodimethylamine (EXP)

nickel dichloride (EXP)

ozone (EXP)

paclitaxel (ISO)

paracetamol (ISO)

paraquat (ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenytoin (EXP)

piperonyl butoxide (ISO)

piroxicam (ISO)

resveratrol (ISO)

selenium atom (ISO)

sodium arsenite (EXP,ISO)

sodium fluoride (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

tremolite asbestos (ISO)

usnic acid (ISO)

valproic acid (ISO)

vinclozolin (ISO)

zidovudine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G0 to G1 transition (IEA,ISO)

negative regulation of Notch signaling pathway (IEA,ISO)

negative regulation of triglyceride metabolic process (IMP)

positive regulation of transcription by RNA polymerase II (IBA,IEA,ISO)

protein ubiquitination (IDA)

regulation of transcription by RNA polymerase II (IEA)

Cellular Component

CKM complex (IEA,ISO)

cyclin-dependent protein kinase holoenzyme complex (IEA,ISO)

mediator complex (IBA,IEA,ISO)

nucleus (IBA,IEA)

protein-containing complex (IEA)

ubiquitin ligase complex (IDA)

Molecular Function

cyclin-dependent protein serine/threonine kinase regulator activity (IBA,IEA)

identical protein binding (IEA,ISO)

protein binding (ISO)

ubiquitin protein ligase activity (IDA)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase II transcription pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.	Brower CS, etal., Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10353-8. Epub 2002 Jul 29.
2.	Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3).	Demetrick DJ, etal., Cytogenet Cell Genet 1995;69(3-4):190-2.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Molecular cloning and chromosomal localization of the human cyclin C (CCNC) and cyclin E (CCNE) genes: deletion of the CCNC gene in human tumors.	Li H, etal., Genomics 1996 Mar 1;32(2):253-9.
6.	Gene Data Set	MGD Curation, June 12, 2002
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	The Mediator complex and transcription regulation.	Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
10.	GOA pipeline	RGD automated data pipeline
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	Comprehensive gene review and curation	RGD comprehensive gene curation
13.	Cyclin G: a new mammalian cyclin with homology to fission yeast Cig1.	Tamura K, etal., Oncogene 1993 Aug;8(8):2113-8.
14.	[Influence of aerosols on the expression of cyclin B1, cyclin C and proliferating cell nuclear antigen in wound tissue healing of burned rat models]	Zhang T, etal., Zhonghua Wai Ke Za Zhi. 2005 Oct 1;43(19):1280-3.
15.	Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1.	Zhao X, etal., J Clin Invest. 2012 Jul 2;122(7):2417-27. doi: 10.1172/JCI61462. Epub 2012 Jun 11.

Additional References at PubMed

PMID:12477932	PMID:15340084	PMID:19103257

Genomics

Comparative Map Data

Ccnc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	40,063,589 - 40,081,731 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	40,063,623 - 40,093,370 (+)	Ensembl				GRCr8
mRatBN7.2	5	35,266,828 - 35,284,943 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	35,266,823 - 35,296,584 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	37,391,253 - 37,409,196 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	38,983,996 - 39,001,939 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	38,923,510 - 38,941,449 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	35,865,598 - 35,883,732 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	35,865,605 - 35,883,706 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	40,521,947 - 40,540,039 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	36,465,490 - 36,483,538 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	34,283,507 - 34,301,554 (+)	NCBI		Celera
RGSC_v3.1	5	36,465,668 - 36,482,416 (+)	NCBI
Cytogenetic Map	5	q21	NCBI

CCNC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	99,542,387 - 99,568,814 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	99,542,387 - 99,568,825 (-)	Ensembl			hg38	GRCh38
GRCh37	6	99,990,263 - 100,016,690 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	100,096,984 - 100,123,411 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	100,097,585 - 100,123,213	NCBI
Celera	6	100,634,399 - 100,660,812 (-)	NCBI		Celera
Cytogenetic Map	6	q16.2	NCBI
HuRef	6	97,430,596 - 97,457,015 (-)	NCBI		HuRef
CHM1_1	6	100,253,182 - 100,279,594 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	100,716,675 - 100,743,083 (-)	NCBI		T2T-CHM13v2.0

Ccnc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	21,727,705 - 21,759,917 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	21,727,701 - 21,759,922 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	21,727,701 - 21,759,922 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	21,727,701 - 21,759,922 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	21,654,850 - 21,677,693 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	21,818,565 - 21,841,381 (+)	NCBI		MGSCv36	mm8
Celera	4	21,472,732 - 21,495,573 (+)	NCBI		Celera
Cytogenetic Map	4	A3	NCBI
cM Map	4	8.86	NCBI

Ccnc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	25,415,023 - 25,447,874 (-)	Ensembl
ChiLan1.0	NW_004955411	25,415,023 - 25,447,874 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCNC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	119,588,885 - 119,615,194 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	117,470,054 - 117,496,887 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	97,383,290 - 97,410,068 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	101,265,499 - 101,292,233 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	101,265,499 - 101,292,233 (-)	Ensembl			panPan2	panpan1.1

CCNC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	57,738,576 - 57,760,918 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	57,739,616 - 57,759,609 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	57,495,633 - 57,522,278 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	58,560,188 - 58,586,841 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	58,560,188 - 58,586,767 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	57,916,655 - 57,943,256 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	57,763,569 - 57,790,252 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	58,009,273 - 58,035,972 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ccnc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	92,668,123 - 92,703,700 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936651	1,140,895 - 1,163,944 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936651	1,123,546 - 1,159,089 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCNC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	66,471,782 - 66,499,188 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	66,472,622 - 66,499,754 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	75,149,770 - 75,175,355 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCNC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	74,312,485 - 74,338,843 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	74,312,228 - 74,339,369 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	46,644,816 - 46,671,444 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccnc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624810	5,466,981 - 5,485,930 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624810	5,466,972 - 5,485,932 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ccnc
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	121,594,991 - 121,611,212 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ccnc
77 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	121
Count of miRNA genes:	95
Interacting mature miRNAs:	101
Transcripts:	ENSRNOT00000011442
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	38011670	83011670	Rat
2293666	Bmd38	Bone mineral density QTL 38	4.4		femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	5	13731153	43590997	Rat
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	32751649	77751649	Rat
6907115	Mcs29	Mammary carcinoma susceptibility QTL 29			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	38004331	83004331	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	23671493	79046465	Rat
1300117	Hrtrt8	Heart rate QTL 8	3.49		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	8627230	52665523	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	17576633	62576633	Rat
1578774	Tcas8	Tongue tumor susceptibility QTL 8	3.47		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	15707451	60707451	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	38011670	83011670	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	38011670	83011670	Rat
1331782	Rf36	Renal function QTL 36	3.296		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	39019942	102105896	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	33311673	78311673	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	32751649	77751649	Rat
1549901	Neudeg2	Neurodegradation QTL 2	4	0	nervous system integrity trait (VT:0010566)	mononuclear cell count (CMO:0002119)	5	31130421	48841739	Rat
1641922	Alcrsp8	Alcohol response QTL 8			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	5	17486080	62486080	Rat
2313085	Bss59	Bone structure and strength QTL 59	2.9	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	5	8627230	53627230	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	39985948	84985948	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	6922282	81330203	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33311673	78311673	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	39526924	84526924	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	14606078	59606078	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	91770353	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
8662454	Vetf3	Vascular elastic tissue fragility QTL 3	27.4		artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	5	7065535	74335773	Rat
1641903	Alcrsp3	Alcohol response QTL 3			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	17486080	62486080	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	87027358	Rat
8552954	Pigfal14	Plasma insulin-like growth factor 1 level QTL 14	9		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	26023211	71023211	Rat
2303577	Gluco47	Glucose level QTL 47	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	16520019	61520019	Rat
1600358	Mamtr5	Mammary tumor resistance QTL 5			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	23671493	68671493	Rat

Markers in Region

RH129921

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	35,284,590 - 35,284,807 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	35,883,380 - 35,883,596	NCBI	Rnor6.0
Rnor_5.0	5	40,539,687 - 40,539,903	UniSTS	Rnor5.0
RGSC_v3.4	5	36,483,186 - 36,483,402	UniSTS	RGSC3.4
Celera	5	34,301,202 - 34,301,418	UniSTS
RH 3.4 Map	5	199.81	UniSTS
Cytogenetic Map	5	q21	UniSTS

RH129977

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	35,284,640 - 35,284,821 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	35,883,430 - 35,883,610	NCBI	Rnor6.0
Rnor_5.0	5	40,539,737 - 40,539,917	UniSTS	Rnor5.0
RGSC_v3.4	5	36,483,236 - 36,483,416	UniSTS	RGSC3.4
Celera	5	34,301,252 - 34,301,432	UniSTS
RH 3.4 Map	5	166.6	UniSTS
Cytogenetic Map	5	q21	UniSTS

BI284677

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	35,281,898 - 35,282,114 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	35,880,688 - 35,880,903	NCBI	Rnor6.0
Rnor_5.0	5	40,536,995 - 40,537,210	UniSTS	Rnor5.0
RGSC_v3.4	5	36,480,494 - 36,480,709	UniSTS	RGSC3.4
Celera	5	34,298,510 - 34,298,725	UniSTS
RH 3.4 Map	9	813.9	UniSTS
Cytogenetic Map	5	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100472	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC161908	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000011442 ⟹ ENSRNOP00000011442

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	40,063,623 - 40,081,725 (+)	Ensembl
mRatBN7.2 Ensembl	5	35,266,860 - 35,284,941 (+)	Ensembl
Rnor_6.0 Ensembl	5	35,865,605 - 35,883,706 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107276 ⟹ ENSRNOP00000095999

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	40,063,623 - 40,093,370 (+)	Ensembl
mRatBN7.2 Ensembl	5	35,266,823 - 35,296,584 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110130 ⟹ ENSRNOP00000086557

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	40,063,636 - 40,079,141 (+)	Ensembl
mRatBN7.2 Ensembl	5	35,266,893 - 35,282,372 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112239 ⟹ ENSRNOP00000079034

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	40,065,597 - 40,078,795 (+)	Ensembl
mRatBN7.2 Ensembl	5	35,268,807 - 35,282,007 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000133466 ⟹ ENSRNOP00000104720

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	40,063,623 - 40,081,725 (+)	Ensembl

RefSeq Acc Id:

NM_001100472 ⟹ NP_001093942

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	40,063,683 - 40,081,731 (+)	NCBI
mRatBN7.2	5	35,266,893 - 35,284,943 (+)	NCBI
Rnor_6.0	5	35,865,684 - 35,883,732 (+)	NCBI
Rnor_5.0	5	40,521,947 - 40,540,039 (+)	NCBI
RGSC_v3.4	5	36,465,490 - 36,483,538 (+)	RGD
Celera	5	34,283,507 - 34,301,554 (+)	RGD

Sequence:

show sequence

AGTTCAATCCAGCCGGTCTGGTTGAGTAACACAGTCCAGGGACTGTGTCTATGGTTGCTCCGCG
GGCCGCTTTGCCGGCTGGTGCTTTTGTATCAGGGCAAGCAGTATTCCATGGCAGGGAACTTCTG
GCAGAGCTCCCACTATTTGCAGTGGATTTTGGATAAACAAGATCTGTTGAAAGAGCGCCAGAAG
GACCTAAAGTTTCTCTCAGAAGAGGAGTATTGGAAATTACAAATATTTTTTACAAATGTTATCC
AAGCATTAGGGGAACATCTTAAATTAAGACAACAAGTTATTGCTACTGCTACAGTCTATTTCAA
GAGATTCTATGCCAGGTATTCTCTGAAAAGTATAGATCCTGTATTAATGGCTCCTACATGTGTG
TTTCTGGCATCCAAAGTAGAGGAATTTGGTGTCGTCTCAAATACAAGATTGATTGCTGCTACTA
CTTCTGTATTAAAAACTAGATTTTCATATGCCTTTCCAAAGGAATTTCCTTACAGGATGAATCA
TATACTAGAATGTGAATTTTACCTCTTAGAATTAATGGACTGTTGCTTGATAGTGTATCATCCT
TATAGACCTTTGCTCCAGTATGTGCAGGACATGGGCCAAGAAGACGTGTTGCTTCCCCTTGCAT
GGAGGATAGTGAATGACACCTACAGGACGGATCTTTGTCTTCTGTATCCTCCTTTCATGATAGC
TTTAGCTTGCCTACATGTAGCCTGTGTTGTACAACAGAAAGACGCTAGACAATGGTTTGCAGAA
CTTTCTGTGGATATGGAGAAGATTTTGGAAATAATCAGGGTTATTTTAAAACTGTATGAGCAGT
GGAAGAATTTTGATGAGAGAAAAGAGATGGCGACTATTCTTAGTAAGATGCCGAAACCAAAACC
ACCTCCGAACAGTGAAGGAGAGCAGGGTCCAAATGGAAGTCAGAACTCTAGCTACAGCCAATCT
TAAAACACCCTGAAGAATCCCGTAGTGGACCACTTGGAAGGAAAGCATTGGAGAGTTTGAGTAA
TGTCTTCATTGGAAAGCAGATGCAAATGAATAGCTTGTTTCTGTCGAGCATATTGGGAATTGAC
TTAATTTCCACAAAATAAGTTTCATTTCCTAACTTGATTCTAGTGTATAATTTATTAAATCTTA
ATTACAAAATTTAGTGAGACTCTTAAGGAACCTATAGCCATATACAAACATTTCAGGGTTAACT
TCTCTTTTACATACTCATGCACATAGACACATACTAGTACTGGTTTTTTATTAGGAAATTGAAG
GGTTTATTATCTTTTTTGTATTAAGTCAGGAAGCATGAAATGTCATTTGTTCACATTTTTCTTT
GGGCATTGAGGGACCAAAAAGGACATAAAAAGTCAATAAAACTCCCCCCGACCCAATTAAATTT
TAAAACTAGATTTAAGAAGTTAAATCTTAGAAAATCCTAGGTTTTAGAAATGATAATTACAATT
TGAAGGAGATTAATCAAGAGCTTACTGATTTTAAAATATATTGTATTCAATACTTTTTGTATCA
TCACAGAAGATACTGGCCCAGCCTATCAAAAAAGTGCAATATATATATATATATATATAGCATA
CCTTGACAATGTAAAGGTTGTATTGACTTACTAGCTGTATTGAAATGCTGGGAAACCTGAAAGA
AAAGGCTATTTACAACTAATTTATAGTTATTAAGCATTTTAAAAGTTTAATTTGATTAAATGCT
TAAGTTAAAATTTGGTGAAATTTTAATGTTTAATTTGTCCTGAAATTTTTTATGAGACATATAT
ACCCGATTTAATTTTAGTGTTTTAGTGTAAGCTAACAGATGTACAGAAGGCATTCTGAGTTGGG
AAGGAACCTGGTCAGGTTTTAGGCCAGTAAGATTCTTAATTCTCATGGGTATAGACTTCAGGAT
AAATGTTACATTTGTGAGACTTCATAAATTAACTCATTTTCTTCAGACTCAAAGGAAGAAGTAT
AAATAAAACTTGGAGTAATGAGATATTATTGTGTAGTTTTGCACTTTTTAAAAAATCATGAAAA
AATTACTCAGTGTTGACTTCCTGGTTAAAATTGGAAGAATAAAAGTTAAGTTTTTCAGCTATAT
TCACTAATGTCTTGAATTCCTGTTGCTAAGTTTGACTTAGGGTTTCTGAGACTCTTTGTGCATG
TTAAATTAGAACCCTAAACTTTGTAAAGGGGTGATTTTGCCTGGTTTATGAATAGAGGAATATG
AGGAAAGTTCTGCTTCTGTGTGGAGAGTATCAGATGCAGATGCACTGGAAAGGGAACAAATATG
GGCTCTGCTAAGGTCGTACAGGGATAAGAAACCAACCAACAGGCTCTCCCAGGCCTGAAGGGTT
AATCCAAGCTTAGCTTGGATGTTAGTGATTGCTTCTCACAGCCATTAACTGCAGTTTTATATTT
AGGCTTTTTTAAATCCAGTTTCTTTTTTCAGATTTATCTTTGTGCTTCATAGTTTTTTTGCAAA
TGCTATTGTGGAAAATTAAGATTTTGCAAGAGCAGACAAAGCAGTGAAGTAAACCTCCATGTGT
GTATGATGTAGCCTCAGCTATTACTGATTCGTAGCCAGTTTCACCTTATTTAAACTTCCACACC
AGTCTCCAGTTTGTATATTATTTTGAAGAAAATTCTAGATATATCATTTTATCCATAAATATTT
CATACTCATAATAGGTAAAATAATTATTTAATATTATATTAAAATTCTCAATTCCCTGAGCGTT
GCAGAGCATTCTTTGAATTCATTTATAAATCCTTTTAGTTTTAGATTCATGGATTCTTCCTCCA
TTCTATAACATGCCCTGCTTTCATTTGTTCATATATTAAGCTCCCGTAGCCTATGTGTTACTGT
GAGCATTTTTAGCATGCCATTTAGTGAGGGTTTTTCTCCTTTGTATTTCCGTAAACTGATAATT
GCCTTTGAAGGCTGACCACATTGAGATTCTTTTTGGTTTGGCTAGACTACTGTAGGGTGGTGTC
TCTTGCATTAGTCAACACATAGTGGCTGTTGCTGAATTGTCCTCACTTATGACAAGTACTGTTT
CAGATTCAGTCATAGGCACACTGTCCAGTCTCAGCCACCAGCCACTTACAGATGAACAGTTACT
ATGTGGCTTGTCTGAATGCAGATATGCGTAAATGTGCAAACATGTTGGAATTCAGGTACTTACT
AATACAACACAAAATAATGTTAAAAATCTCAATTTGTTTATAACCATTATGTGTTTTAAATGAT
AATATTTTGGATACATAGAATTAAATAAAACATTGTTAAAATA

hide sequence

RefSeq Acc Id:

XM_006237937 ⟹ XP_006237999

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	40,063,589 - 40,081,731 (+)	NCBI
mRatBN7.2	5	35,266,846 - 35,282,375 (+)	NCBI
Rnor_6.0	5	35,865,598 - 35,881,164 (+)	NCBI
Rnor_5.0	5	40,521,947 - 40,540,039 (+)	NCBI

Sequence:

show sequence

GCCGGAACCGGTGTATGCTGCTCAGTGTTGTCGGCCGGCGTCAAGGCGACGGTGTTGTTCTCTT
CCTCTGACTGCGGTTGCTGTTCAGTTCAATCCAGCCGGTCTGGTTGAGTAACACAGTCCAGGGA
CTGTGTCTATGGTTGCTCCGCGGGCCGCTTTGCCGGCTGGTGCTTTTGTATCAGGGCAAGCAGT
ATTCCATGGCAGGGAACTTCTGGCAGAGCTCCCACTATTTGCAGTGGATTTTGGATAAACAAGA
TCTGTTGAAAGAGCGCCAGAAGGACCTAAAGTTTCTCTCAGAAGAGGAGTATTGGAAATTACAA
ATATTTTTTACAAATGTTATCCAAGCATTAGGGGAACATCTTAAATTAAGACAACAAGTTATTG
CTACTGCTACAGTCTATTTCAAGAGATTCTATGCCAGGTATTCTCTGAAAAGTATAGATCCTGT
ATTAATGGCTCCTACATGTGTGTTTCTGGCATCCAAAGTAGAGGAATTTGGTGTCGTCTCAAAT
ACAAGATTGATTGCTGCTACTACTTCTGTATTAAAAACTAGATTTTCATATGCCTTTCCAAAGG
AATTTCCTTACAGGATGAATCATATACTAGAATGTGAATTTTACCTCTTAGAATTAATGGACTG
TTGCTTGATAGTGTATCATCCTTATAGACCTTTGCTCCAGTATGTGCAGGACATGGGCCAAGAA
GACGTGTTGCTTCCCCTTGCATGGAGGATAGTGAATGACACCTACAGGACGGATCTTTGTCTTC
TGTATCCTCCTTTCATGATAGCTTTAGCTTGCCTACATGTAGCCTGTGTTGTACAACAGAAAGA
CGCTAGACAATGGTTTGCAGAACTTTCTGTGGATATGGAGAAGATTTTGGAAATAATCAGGGTT
ATTTTAAAACTGTATGAGCAGTGGAAGAATTTTGATGAGAGAAAAGAGATGGCGACTATTCTTA
GTAAGATGCCGAAACCAAAACCACCTCCGAACAGAAGCTCCCTGAGTGATTCTCCACTAATGGC
AGGGCCTGAAGCTGCAAGATGATGGTGGACAAGATAATGCAATCTCCTATTGTCACAGTTACTG
GTATTTTCAGCTTTAGTTATTTTTATTTTAATATTCGGCATTTTTCCAAGAAATCACCATATTT
TTGATGTATAAAGATTTGTTATCATTTCCATATGATTTTATGCCATTGGACAACAGTTTTTTTT
CTTTTTTCTTTCTTTTTTTTTTTTGAAAGACATTTTGGATTTTCCTAAAGAGTAGAAATAGAAT
TTTATATGTCAGATTTAATTTTGTAGGAAATTCGTTCAGAAGAAGTTGTAATCTCTATGTTGAG
TGATACCTGTAATAATGTGAAACCCTAAACTCTAACTTAAATCTTTGAATGTATATGGACACTA
ACTTCTGGACTGCTTGTTATGTATGAGGGCCTCAAGTTACAGAAGAATAAAAACATAAAACCAA

hide sequence

RefSeq Acc Id:

XM_039109128 ⟹ XP_038965056

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	40,063,589 - 40,081,731 (+)	NCBI
mRatBN7.2	5	35,266,845 - 35,284,943 (+)	NCBI

RefSeq Acc Id:

XM_063287061 ⟹ XP_063143131

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	40,063,589 - 40,079,163 (+)	NCBI

RefSeq Acc Id:

XM_063287062 ⟹ XP_063143132

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	40,067,426 - 40,079,163 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001093942	(Get FASTA)	NCBI Sequence Viewer
	XP_006237999	(Get FASTA)	NCBI Sequence Viewer
	XP_038965056	(Get FASTA)	NCBI Sequence Viewer
	XP_063143131	(Get FASTA)	NCBI Sequence Viewer
	XP_063143132	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL98512	(Get FASTA)	NCBI Sequence Viewer
	EDL98513	(Get FASTA)	NCBI Sequence Viewer
	EDL98514	(Get FASTA)	NCBI Sequence Viewer
	EDL98515	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011442
	ENSRNOP00000086557
	ENSRNOP00000095999
GenBank Protein	P39947	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001093942 ⟸ NM_001100472

- UniProtKB:

P39947 (UniProtKB/Swiss-Prot), G3V738 (UniProtKB/TrEMBL), A6IIE2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIAT
ATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKTRFSYAFPKEF
PYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLAWRIVNDTYRTDLCLLY
PPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSK
MPKPKPPPNSEGEQGPNGSQNSSYSQS

hide sequence

RefSeq Acc Id:	XP_006237999 ⟸ XM_006237937
- Peptide Label:	isoform X2
- UniProtKB:	P39947 (UniProtKB/Swiss-Prot), A0A8I6A408 (UniProtKB/TrEMBL), A6IIE3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIAT ATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKTRFSYAFPKEF PYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLAWRIVNDTYRTDLCLLY PPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSK MPKPKPPPNRSSLSDSPLMAGPEAAR hide sequence

Ensembl Acc Id:

ENSRNOP00000011442 ⟸ ENSRNOT00000011442

RefSeq Acc Id:	XP_038965056 ⟸ XM_039109128
- Peptide Label:	isoform X2
- UniProtKB:	P39947 (UniProtKB/Swiss-Prot), A0A8I6A408 (UniProtKB/TrEMBL), A6IIE3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000079034 ⟸ ENSRNOT00000112239

Ensembl Acc Id:

ENSRNOP00000086557 ⟸ ENSRNOT00000110130

Ensembl Acc Id:

ENSRNOP00000095999 ⟸ ENSRNOT00000107276

RefSeq Acc Id:	XP_063143131 ⟸ XM_063287061
- Peptide Label:	isoform X1
- UniProtKB:	P39947 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063143132 ⟸ XM_063287062
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000104720 ⟸ ENSRNOT00000133466

Protein Domains

Cyclin N-terminal Cyclin-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P39947-F1-model_v2	AlphaFold	P39947	1-278	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693594

Promoter ID:

EPDNEW_R4119

Type:

multiple initiation site

Name:

Ccnc_1

Description:

cyclin C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	35,865,684 - 35,865,744	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:70905	AgrOrtholog
BioCyc Gene	G2FUF-41816	BioCyc
Ensembl Genes	ENSRNOG00000007719	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000011442	ENTREZGENE
	ENSRNOT00000107276	ENTREZGENE
	ENSRNOT00000110130	ENTREZGENE
Gene3D-CATH	Cyclin-like	UniProtKB/Swiss-Prot
InterPro	Cyclin-like	UniProtKB/Swiss-Prot
	Cyclin-like_sf	UniProtKB/Swiss-Prot
	Cyclin/Ssn8	UniProtKB/Swiss-Prot
	Cyclin_C_2	UniProtKB/Swiss-Prot
	Cyclin_N	UniProtKB/Swiss-Prot
NCBI Gene	114839	ENTREZGENE
PANTHER	PTHR10026	UniProtKB/Swiss-Prot
Pfam	Cyclin_C_2	UniProtKB/Swiss-Prot
	Cyclin_N	UniProtKB/Swiss-Prot
PhenoGen	Ccnc	PhenoGen
PIRSF	Cyclin, C/H/G types	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000007719	RatGTEx
SMART	CYCLIN	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47954	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZM04_RAT	UniProtKB/TrEMBL
	A0A8I6A408	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AP22_RAT	UniProtKB/TrEMBL
	A0ABK0LIN7_RAT	UniProtKB/TrEMBL
	A6IIE2	ENTREZGENE, UniProtKB/TrEMBL
	A6IIE3	ENTREZGENE, UniProtKB/TrEMBL
	A6IIE4_RAT	UniProtKB/TrEMBL
	A6IIE5_RAT	UniProtKB/TrEMBL
	CCNC_RAT	UniProtKB/Swiss-Prot
	G3V738	ENTREZGENE, UniProtKB/TrEMBL
	P39947	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-07-09	Ccnc	cyclin C			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_disease	human homolog is deleted in a subset of acute lymphoblastic leukemias	728375

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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RGD Manual Annotations