Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rps27a | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Rps27a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RPS27A mRNA | CTD | PMID:36331819 | Rps27a | Rat | (S)-nicotine | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Nicotine results in decreased expression of RPS27A protein | CTD | PMID:30272249 | Rps27a | Rat | (S)-nicotine | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [[Nicotine results in decreased expression of RPS27A protein] which results in increased phosphorylation of MDM2 more ... | CTD | PMID:30272249 | Rps27a | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Rps27a (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of RPS27A mRNA] | CTD | PMID:22206623 | Rps27a | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of RPS27A mRNA | CTD | PMID:22206623 | Rps27a | Rat | 17beta-estradiol | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Estradiol results in decreased expression of RPS27A mRNA | CTD | PMID:23019147 | Rps27a | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Rps27a (Mus musculus) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether affects the expression of RPS27A mRNA | CTD | PMID:30294300 | Rps27a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rps27a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RPS27A mRNA | CTD | PMID:21570461 | Rps27a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RPS27A mRNA | CTD | PMID:33387578|PMID:34747641 | Rps27a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RPS27A mRNA | CTD | PMID:32109520 | Rps27a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RPS27A mRNA | CTD | PMID:26290441 | Rps27a | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of RPS27A mRNA | CTD | PMID:21346803 | Rps27a | Rat | 2-hydroxypropanoic acid | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of RPS27A mRNA | CTD | PMID:30851411 | Rps27a | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Rps27a (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of RPS27A mRNA | CTD | PMID:26251327 | Rps27a | Rat | 3,4-methylenedioxymethamphetamine | increases methylation | ISO | Rps27a (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased methylation of RPS27A promoter | CTD | PMID:26251327 | Rps27a | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of RPS27A mRNA | CTD | PMID:18648102 | Rps27a | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Rps27a (Mus musculus) | 6480464 | bisphenol S results in decreased expression of RPS27A mRNA | CTD | PMID:39298647 | Rps27a | Rat | 7,12-dimethyltetraphene | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | 9,10-Dimethyl-1,2-benzanthracene results in increased expression of RPS27A protein | CTD | PMID:39910959 | Rps27a | Rat | acetylsalicylic acid | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Aspirin results in increased expression of RPS27A mRNA | CTD | PMID:15928584 | Rps27a | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of RPS27A mRNA | CTD | PMID:33354967 | Rps27a | Rat | all-trans-retinoic acid | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RPS27A mRNA | CTD | PMID:33167477 | Rps27a | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of RPS27A mRNA | CTD | PMID:16483693 | Rps27a | Rat | amosite asbestos | decreases expression | ISO | Rps27a (Mus musculus) | 6480464 | Asbestos, Amosite results in decreased expression of RPS27A mRNA | CTD | PMID:23917077 | Rps27a | Rat | arsane | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:35809665|PMID:39836092 | Rps27a | Rat | arsenic atom | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:35809665|PMID:39836092 | Rps27a | Rat | arsenic trichloride | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression more ... | CTD | PMID:35809665 | Rps27a | Rat | arsenite(3-) | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to RPS27A mRNA]; arsenite promotes the reaction [G3BP1 more ... | CTD | PMID:32406909 | Rps27a | Rat | arsenous acid | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of RPS27A mRNA | CTD | PMID:20458559 | Rps27a | Rat | atrazine | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Atrazine results in decreased expression of RPS27A mRNA | CTD | PMID:22378314 | Rps27a | Rat | Azaspiracid | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | azaspiracid results in increased expression of RPS27A mRNA | CTD | PMID:28939011 | Rps27a | Rat | azoxystrobin | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | azoxystrobin results in increased expression of RPS27A mRNA | CTD | PMID:33512557 | Rps27a | Rat | benzatropine | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Benztropine results in increased expression of RPS27A protein | CTD | PMID:34122009 | Rps27a | Rat | benzene | affects expression | EXP | | 6480464 | Benzene affects the expression of RPS27A mRNA | CTD | PMID:15878777 | Rps27a | Rat | benzo[a]pyrene | multiple interactions | ISO | Rps27a (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RPS27A mRNA] | CTD | PMID:22228805 | Rps27a | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Rps27a (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of RPS27A mRNA | CTD | PMID:19850644 | Rps27a | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Rps27a (Mus musculus) | 6480464 | PPARA protein inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of RPS27A mRNA] | CTD | PMID:19850644 | Rps27a | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RPS27A mRNA | CTD | PMID:25181051 | Rps27a | Rat | bisphenol A | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | bisphenol A results in increased expression of RPS27A protein | CTD | PMID:34186270 | Rps27a | Rat | bisphenol A | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | bisphenol A results in increased expression of RPS27A mRNA | CTD | PMID:32156529|PMID:38074096 | Rps27a | Rat | bisphenol A | decreases expression | ISO | Rps27a (Mus musculus) | 6480464 | bisphenol A results in decreased expression of RPS27A mRNA | CTD | PMID:35598803 | Rps27a | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RPS27A mRNA | CTD | PMID:30903817 | Rps27a | Rat | bisphenol A | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RPS27A mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:29275510|PMID:33376534 | Rps27a | Rat | bisphenol A | affects expression | ISO | RPS27A (Homo sapiens) | 6480464 | bisphenol A affects the expression of RPS27A mRNA | CTD | PMID:30903817 | Rps27a | Rat | bisphenol AF | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of RPS27A protein | CTD | PMID:34186270 | Rps27a | Rat | Butylbenzyl phthalate | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased expression of RPS27A mRNA | CTD | PMID:28392331 | Rps27a | Rat | cadmium atom | multiple interactions | ISO | Rps27a (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RPS27A more ... | CTD | PMID:28111341 | Rps27a | Rat | cadmium dichloride | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of RPS27A mRNA | CTD | PMID:26558471 | Rps27a | Rat | cadmium dichloride | multiple interactions | ISO | Rps27a (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RPS27A more ... | CTD | PMID:28111341 | Rps27a | Rat | caffeine | affects phosphorylation | ISO | RPS27A (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of RPS27A protein | CTD | PMID:35688186 | Rps27a | Rat | cannabidiol | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Cannabidiol results in decreased expression of RPS27A mRNA | CTD | PMID:31801206 | Rps27a | Rat | CGP 52608 | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to RPS27A gene] | CTD | PMID:28238834 | Rps27a | Rat | chloropicrin | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of RPS27A mRNA | CTD | PMID:26352163 | Rps27a | Rat | cisplatin | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | Cisplatin results in increased expression of RPS27A mRNA | CTD | PMID:32738330 | Rps27a | Rat | clofibric acid | affects expression | EXP | | 6480464 | Clofibric Acid affects the expression of RPS27A mRNA | CTD | PMID:17602206 | Rps27a | Rat | copper atom | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression more ... | CTD | PMID:35809665 | Rps27a | Rat | copper(0) | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [Copper co-treated with [arsenic trichloride results in increased abundance of Arsenic]] results in decreased expression more ... | CTD | PMID:35809665 | Rps27a | Rat | crocidolite asbestos | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in increased expression of RPS27A protein | CTD | PMID:29553831 | Rps27a | Rat | Cuprizon | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [Cuprizone co-treated with Haloperidol] results in increased expression of RPS27A protein | CTD | PMID:34122009 | Rps27a | Rat | Cyclopamine | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | cyclopamine results in increased expression of RPS27A mRNA | CTD | PMID:39714734 | Rps27a | Rat | cypermethrin | decreases expression | ISO | Rps27a (Mus musculus) | 6480464 | cypermethrin results in decreased expression of RPS27A mRNA | CTD | PMID:29020013 | Rps27a | Rat | DDT | increases methylation | EXP | | 6480464 | DDT results in increased methylation of RPS27A gene | CTD | PMID:31682807 | Rps27a | Rat | diarsenic trioxide | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of RPS27A mRNA | CTD | PMID:20458559 | Rps27a | Rat | dicrotophos | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of RPS27A mRNA | CTD | PMID:28302478 | Rps27a | Rat | dinophysistoxin 1 | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | dinophysistoxin 1 results in increased expression of RPS27A mRNA | CTD | PMID:28939011 | Rps27a | Rat | enzalutamide | affects expression | ISO | RPS27A (Homo sapiens) | 6480464 | enzalutamide affects the expression of RPS27A mRNA | CTD | PMID:30940724 | Rps27a | Rat | enzyme inhibitor | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Rps27a | Rat | epoxiconazole | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | epoxiconazole results in increased expression of RPS27A mRNA | CTD | PMID:35436446 | Rps27a | Rat | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of RPS27A protein | CTD | PMID:19609968 | Rps27a | Rat | ethanol | affects splicing | ISO | Rps27a (Mus musculus) | 6480464 | Ethanol affects the splicing of RPS27A mRNA | CTD | PMID:30319688 | Rps27a | Rat | fenpyroximate | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | fenpyroximate results in increased expression of RPS27A mRNA | CTD | PMID:33512557 | Rps27a | Rat | fenthion | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | Fenthion results in increased expression of RPS27A mRNA | CTD | PMID:34813904 | Rps27a | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of RPS27A mRNA | CTD | PMID:23962444 | Rps27a | Rat | folic acid | multiple interactions | ISO | Rps27a (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of RPS27A mRNA] | CTD | PMID:22206623 | Rps27a | Rat | FR900359 | decreases phosphorylation | ISO | RPS27A (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of RPS27A protein | CTD | PMID:37730182 | Rps27a | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of RPS27A gene | CTD | PMID:22079235 | Rps27a | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of RPS27A mRNA | CTD | PMID:22061828 | Rps27a | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of RPS27A mRNA | CTD | PMID:33387578 | Rps27a | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of RPS27A mRNA | CTD | PMID:24136188 | Rps27a | Rat | haloperidol | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [Cuprizone co-treated with Haloperidol] results in increased expression of RPS27A protein | CTD | PMID:34122009 | Rps27a | Rat | hydralazine | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of RPS27A mRNA | CTD | PMID:17183730 | Rps27a | Rat | indometacin | increases expression | EXP | | 6480464 | Indomethacin results in increased expression of RPS27A mRNA | CTD | PMID:36868495 | Rps27a | Rat | isoprenaline | decreases expression | ISO | Rps27a (Mus musculus) | 6480464 | Isoproterenol results in decreased expression of RPS27A mRNA | CTD | PMID:21335049 | Rps27a | Rat | ivermectin | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RPS27A protein | CTD | PMID:32959892 | Rps27a | Rat | manganese atom | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rps27a | Rat | manganese(0) | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rps27a | Rat | manganese(II) chloride | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rps27a | Rat | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of RPS27A mRNA | CTD | PMID:15644446 | Rps27a | Rat | methylparaben | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | methylparaben results in decreased expression of RPS27A mRNA | CTD | PMID:38568856 | Rps27a | Rat | naphthalene | decreases expression | ISO | Rps27a (Mus musculus) | 6480464 | naphthalene results in decreased expression of RPS27A protein | CTD | PMID:19438287 | Rps27a | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of RPS27A mRNA | CTD | PMID:24136188 | Rps27a | Rat | nicotine | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [[Nicotine results in decreased expression of RPS27A protein] which results in increased phosphorylation of MDM2 more ... | CTD | PMID:30272249 | Rps27a | Rat | nicotine | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Nicotine results in decreased expression of RPS27A protein | CTD | PMID:30272249 | Rps27a | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of RPS27A mRNA | CTD | PMID:24136188 | Rps27a | Rat | paracetamol | affects expression | ISO | Rps27a (Mus musculus) | 6480464 | Acetaminophen affects the expression of RPS27A mRNA | CTD | PMID:15606129|PMID:17562736 | Rps27a | Rat | paracetamol | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | Acetaminophen results in increased expression of RPS27A mRNA; Acetaminophen results in increased expression of RPS27A more ... | CTD | PMID:11264010|PMID:21329376 | Rps27a | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Rps27a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RPS27A mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Rps27a | Rat | picoxystrobin | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | picoxystrobin results in increased expression of RPS27A mRNA | CTD | PMID:33512557 | Rps27a | Rat | potassium dichromate | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of RPS27A mRNA | CTD | PMID:11678601 | Rps27a | Rat | pyrimidifen | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | pyrimidifen results in increased expression of RPS27A mRNA | CTD | PMID:33512557 | Rps27a | Rat | rac-lactic acid | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of RPS27A mRNA | CTD | PMID:30851411 | Rps27a | Rat | rotenone | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | Rotenone results in increased expression of RPS27A mRNA | CTD | PMID:33512557 | Rps27a | Rat | silicon dioxide | affects secretion | ISO | RPS27A (Homo sapiens) | 6480464 | Silicon Dioxide analog affects the secretion of RPS27A protein | CTD | PMID:25895662 | Rps27a | Rat | sodium arsenite | decreases expression | ISO | RPS27A (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of RPS27A mRNA; sodium arsenite results in decreased expression more ... | CTD | PMID:38228842|PMID:38568856|PMID:39719251 | Rps27a | Rat | sodium arsenite | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | sodium arsenite results in increased expression of RPS27A mRNA | CTD | PMID:39095385 | Rps27a | Rat | sodium arsenite | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rps27a | Rat | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of RPS27A mRNA | CTD | PMID:15963342 | Rps27a | Rat | tolcapone | affects binding | EXP | | 6480464 | tolcapone binds to RPS27A protein | CTD | PMID:19783845 | Rps27a | Rat | triamcinolone acetonide | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | Triamcinolone Acetonide results in increased expression of RPS27A mRNA | CTD | PMID:39714734 | Rps27a | Rat | tungsten | increases expression | ISO | Rps27a (Mus musculus) | 6480464 | Tungsten results in increased expression of RPS27A mRNA | CTD | PMID:30912803 | Rps27a | Rat | valproic acid | multiple interactions | ISO | RPS27A (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of RPS27A mRNA | CTD | PMID:17183730 | Rps27a | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of RPS27A mRNA | CTD | PMID:23034163 | Rps27a | Rat | vorinostat | increases expression | ISO | RPS27A (Homo sapiens) | 6480464 | vorinostat results in increased expression of RPS27A mRNA | CTD | PMID:27188386 | |





















