Chrna2 Rat Gene (cholinergic receptor, nicotinic, alpha 2 (neuronal))

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Keyword

Gene:
Chrna2 ( Rattus norvegicus )
cholinergic receptor, nicotinic, alpha 2 (neuronal)
Description: agonist-binding subunit of neuronal nicotinic acetylcholine receptor
Synonyms: cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal); ACHR;
ArrayIDs: A_44_P542501; 5860784; 1387574_at; M20297_at; 1384474_at; 5709178; 6630977; 5891863; 6570872; 6339330; 6324260; A_42_P759502; 5687554; 6438582; 6271594; rc_AA860010_at; 5966054; 5916513;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: CHRNA2     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Chrna2     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Chrna2 genome assembly 3.1 15 45586588 - 45602871
Rat Celera Assembly 15 40015644 - 40031870
RGSC genome assembly v3.4 15 45570809 - 45587091
Cytogenetic 15 p12
Mus musculus Chrna2 Mouse genome assembly build 36.1 14 66759797 - 66771785
Cytogenetic 14 14 D1
Homo sapiens CHRNA2 human genome assembly 8 27374181 - 27392675
Human genome assembly build 36.2 8 27374182 - 27392675
Cytogenetic 8 p21

View comparative maps:      NCBI MapViewer

Genome
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Annotation
Molecular Function

Gene Ontology

acetylcholine receptor activity,  acetylcholine binding,  ion channel activity ... (details...)
Biological Process

Gene Ontology

protein heterooligomerization,  signal transduction,  ion transport (details...)
Cellular Component

Gene Ontology

synapse,  nicotinic acetylcholine-gated receptor-channel complex,  integral to membrane ... (details...)

External Links
Databases
DATABASE ID SOURCE
PROSITE: NEUROTR_ION_CHANNEL IPI
UNIPARC: UPI0000125230 IPI
KEGG Report: rno:170945 ENTREZGENE
HomoloGene Group ID: 20193 ENTREZGENE
Germonline: 621533
Pfam: Neur_chan_LBD IPI
Pfam: Neur_chan_memb IPI
InterPro: Nicotinic_acetylcholine_rcpt_N. IPI
InterPro: Neu_channel_TM. IPI
InterPro: Neur_chan_lig_bd. IPI
InterPro: Neur_channel. IPI
InterPro: Neurotransmitter_ion_chnl_CS. IPI
IPI: IPI00196723 IPI
Ensembl Protein: ENSRNOP00000023475 IPI
Gene3D-CATH: Neur_chan_lig_bd IPI
Entrez Gene: Chrna2 ENTREZGENE
UniProt: ACHA2_RAT IPI
Ensembl Genes: ENSRNOG00000017424 IPI
Superfamily-SCOP: Neur_chan_LBD IPI
Superfamily-SCOP: Neu_channel_TM IPI
PANTHER: Neur_channel IPI
TIGRFAMs: LIC IPI
PRINTS: NRIONCHANNEL. IPI
PRINTS: NICOTINICR. IPI
Sequences
Nucleotide: M20295 Get FASTA Search GEO Profiles
Nucleotide: CH474023 Get FASTA Search GEO Profiles
Nucleotide: M20292 Get FASTA Search GEO Profiles
Nucleotide: M20296 Get FASTA Search GEO Profiles
Nucleotide: M20297 Get FASTA Search GEO Profiles
Nucleotide: AY574253 Get FASTA Search GEO Profiles
Nucleotide: NM_133420 Get FASTA Search GEO Profiles
Nucleotide: L10077 Get FASTA Search GEO Profiles
Nucleotide: M20293 Get FASTA Search GEO Profiles
(View all 9 Nucleotide Accessions)
Protein: NP_596911 Get FASTA
Protein: EDL85379 Get FASTA
Protein: EDL85380 Get FASTA
Protein: AAA40664 Get FASTA
Protein: AAS90349 Get FASTA
Protein: AAB60900 Get FASTA
Protein: P12389 Get FASTA
(View all 7 Protein Accessions)
Clusters
UniGene: 9713

References
Curated References
7 references in RGD related to Chrna2

Other References
4 other references at PubMed related to Chrna2

Database Information
RGD ID 621533
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

25-SEP-08: Chrna2 cholinergic receptor, nicotinic, alpha 2 (neuronal) Chrna2 cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863

26-FEB-04: Chrna2 cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) APPROVED Symbol and Name status set to approved 625702

07-AUG-02: Chrna2 cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) PROVISIONAL Symbol and Name status set to provisional 70820