Tradd (TNFRSF1A-associated via death domain) - Rat Genome Database

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Gene: Tradd (TNFRSF1A-associated via death domain) Rattus norvegicus
Analyze
Symbol: Tradd
Name: TNFRSF1A-associated via death domain
RGD ID: 621313
Description: Enables tumor necrosis factor receptor binding activity. Predicted to be involved in several processes, including cellular response to tumor necrosis factor; extrinsic apoptotic signaling pathway; and positive regulation of hair follicle development. Predicted to act upstream of or within several processes, including cell surface receptor signaling pathway; intracellular signaling cassette; and regulation of canonical NF-kappaB signal transduction. Part of protein-containing complex. Orthologous to human TRADD (TNFRSF1A associated via death domain); PARTICIPATES IN ceramide signaling pathway; Toll-like receptor signaling pathway; Trail mediated signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,046,057 - 50,048,158 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1950,046,061 - 50,052,550 (-)EnsemblGRCr8
mRatBN7.21933,136,148 - 33,142,714 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,136,138 - 33,142,638 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1939,951,075 - 39,953,176 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,604,983 - 40,607,084 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01942,894,707 - 42,896,808 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,214,461 - 37,221,099 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,214,471 - 37,216,572 (-)Ensemblrn6Rnor6.0
Rnor_5.01948,081,076 - 48,086,774 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41935,073,150 - 35,075,251 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1932,565,129 - 32,567,230 (-)NCBICelera
RGSC_v3.11935,078,569 - 35,079,048 (-)NCBI
Cytogenetic Map19q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1'-acetoxychavicol acetate  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
all-trans-retinoic acid  (ISO)
Aloe emodin  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
beta-naphthoflavone  (EXP)
Beta-Solamarine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
curcumin  (ISO)
cylindrospermopsin  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
Dibutyl phosphate  (ISO)
dieldrin  (EXP)
dioscin  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethylparaben  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
hesperidin  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hydroxyurea  (ISO)
indometacin  (ISO)
irinotecan  (ISO)
iron(2+) sulfate (anhydrous)  (ISO)
ivermectin  (ISO)
kojic acid  (EXP)
leflunomide  (ISO)
mangiferin  (ISO)
melatonin  (ISO)
menadione  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
metformin  (ISO)
methotrexate  (ISO)
monocrotaline  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nitrates  (EXP,ISO)
o-anisidine  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parthenolide  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
PF-3758309  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
progesterone  (ISO)
propylparaben  (ISO)
pyrethrins  (ISO)
quercetin  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (EXP)
quercetin 3-O-beta-D-glucopyranoside  (EXP)
resveratrol  (ISO)
Rhein  (ISO)
rifampicin  (ISO)
SB 431542  (ISO)
semilicoisoflavone B  (ISO)
simvastatin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
VX nerve agent  (ISO)
zerumbone  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Time course profiling of the retinal transcriptome after optic nerve transection and optic nerve crush. Agudo M, etal., Mol Vis. 2008 Jun 3;14:1050-63.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Role of heme oxygenase 1 in TNF/TNF receptor-mediated apoptosis after hepatic ischemia/reperfusion in rats. Kim SJ, etal., Shock. 2013 Apr;39(4):380-8. doi: 10.1097/SHK.0b013e31828aab7f.
4. Pathogen recognition by the innate immune system. Kumar H, etal., Int Rev Immunol. 2011 Feb;30(1):16-34.
5. Tumor necrosis factor receptor 1 and its signaling intermediates are recruited to lipid rafts in the traumatized brain. Lotocki G, etal., J Neurosci. 2004 Dec 8;24(49):11010-6.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Roy DN, etal., Br J Pharmacol. 2010 Aug;160(7):1823-43.
13. Formation of a tumour necrosis factor receptor 1 molecular scaffolding complex and activation of apoptosis signal-regulating kinase 1 during seizure-induced neuronal death. Shinoda S, etal., Eur J Neurosci. 2003 May;17(10):2065-76.
14. Vulnerability of monoaminergic neurons in the brainstem of the zitter rat in oxidative stress. Ueda S, etal., Prog Brain Res 2002;136:293-302.
15. Tumor necrosis factor signaling. Wajant H, etal., Cell Death Differ. 2003 Jan;10(1):45-65.
Additional References at PubMed
PMID:7758105   PMID:8612133   PMID:11684708   PMID:12761501   PMID:14743216   PMID:16611992   PMID:16702408   PMID:19541932   PMID:22089168   PMID:22510408   PMID:23429285   PMID:23574812  
PMID:25732226   PMID:30561431  


Genomics

Comparative Map Data
Tradd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,046,057 - 50,048,158 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1950,046,061 - 50,052,550 (-)EnsemblGRCr8
mRatBN7.21933,136,148 - 33,142,714 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,136,138 - 33,142,638 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1939,951,075 - 39,953,176 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,604,983 - 40,607,084 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01942,894,707 - 42,896,808 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,214,461 - 37,221,099 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,214,471 - 37,216,572 (-)Ensemblrn6Rnor6.0
Rnor_5.01948,081,076 - 48,086,774 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41935,073,150 - 35,075,251 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1932,565,129 - 32,567,230 (-)NCBICelera
RGSC_v3.11935,078,569 - 35,079,048 (-)NCBI
Cytogenetic Map19q11NCBI
TRADD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,154,185 - 67,159,909 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,153,969 - 67,163,760 (-)Ensemblhg38GRCh38
GRCh371667,188,088 - 67,193,812 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,745,589 - 65,751,313 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341665,745,604 - 65,747,759NCBI
Celera1651,696,331 - 51,702,055 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1653,061,605 - 53,067,329 (-)NCBIHuRef
CHM1_11668,595,406 - 68,601,130 (-)NCBICHM1_1
T2T-CHM13v2.01672,948,477 - 72,954,201 (-)NCBIT2T-CHM13v2.0
Tradd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398105,985,207 - 105,991,226 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8105,984,918 - 105,991,241 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm388105,258,575 - 105,264,594 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,258,286 - 105,264,609 (-)Ensemblmm10GRCm38
MGSCv378107,782,475 - 107,788,494 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368108,147,704 - 108,153,723 (-)NCBIMGSCv36mm8
Celera8109,481,639 - 109,487,742 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Tradd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,456,301 - 9,462,425 (+)Ensembl
ChiLan1.0NW_0049554849,456,268 - 9,462,425 (+)NCBIChiLan1.0ChiLan1.0
TRADD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21876,683,947 - 76,689,812 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11682,596,528 - 82,602,315 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01647,499,881 - 47,506,220 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11666,888,543 - 66,892,501 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1666,889,006 - 66,891,016 (-)EnsemblpanPan2panpan1.1
TRADD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,200,430 - 82,211,430 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,206,111 - 82,210,963 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha582,189,185 - 82,200,059 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0582,634,875 - 82,645,756 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,634,842 - 82,645,749 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,460,961 - 82,471,833 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0582,146,502 - 82,157,169 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,785,778 - 82,796,660 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tradd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,954,016 - 41,960,812 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647517,628,803 - 17,630,856 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647517,628,297 - 17,634,919 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRADD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,797,607 - 27,804,423 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1627,797,594 - 27,804,654 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TRADD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1560,296,777 - 60,303,076 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl560,297,375 - 60,303,579 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604723,048,918 - 23,055,198 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tradd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474619,155,113 - 19,165,705 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474619,155,058 - 19,165,702 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tradd
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11724,986,301 - 24,991,886 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tradd
6 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:67
Count of miRNA genes:59
Interacting mature miRNAs:64
Transcripts:ENSRNOT00000020405
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat

Markers in Region
RH130583  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21933,136,186 - 33,136,397 (+)MAPPERmRatBN7.2
Rnor_6.01937,214,510 - 37,214,720NCBIRnor6.0
Rnor_5.01948,081,125 - 48,081,335UniSTSRnor5.0
RGSC_v3.41935,073,189 - 35,073,399UniSTSRGSC3.4
Celera1932,565,168 - 32,565,378UniSTS
Cytogenetic Map19q11UniSTS
PMC305633P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81950,046,502 - 50,047,029 (+)Marker Load Pipeline
mRatBN7.21933,136,593 - 33,137,120 (+)MAPPERmRatBN7.2
Rnor_6.01937,214,917 - 37,215,443NCBIRnor6.0
Rnor_5.01948,081,532 - 48,082,058UniSTSRnor5.0
RGSC_v3.41935,073,596 - 35,074,122UniSTSRGSC3.4
Celera1932,565,575 - 32,566,101UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020405   ⟹   ENSRNOP00000020405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1950,046,063 - 50,052,550 (-)Ensembl
mRatBN7.2 Ensembl1933,136,138 - 33,142,638 (-)Ensembl
Rnor_6.0 Ensembl1937,214,471 - 37,216,572 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000149535   ⟹   ENSRNOP00000100978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1950,046,061 - 50,052,550 (-)Ensembl
RefSeq Acc Id: NM_001100480   ⟹   NP_001093950
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,046,057 - 50,048,158 (-)NCBI
mRatBN7.21933,136,148 - 33,138,249 (-)NCBI
Rnor_6.01937,214,471 - 37,216,572 (-)NCBI
Rnor_5.01948,081,076 - 48,086,774 (-)NCBI
RGSC_v3.41935,073,150 - 35,075,251 (-)RGD
Celera1932,565,129 - 32,567,230 (-)RGD
Sequence:
RefSeq Acc Id: XM_039097477   ⟹   XP_038953405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81950,046,059 - 50,048,158 (-)NCBI
mRatBN7.21933,136,152 - 33,142,714 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001093950 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953405 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAM74196 (Get FASTA)   NCBI Sequence Viewer  
  EDL92353 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020405
  ENSRNOP00000020405.4
  ENSRNOP00000100978.1
RefSeq Acc Id: NP_001093950   ⟸   NM_001100480
- UniProtKB: D3ZZC5 (UniProtKB/TrEMBL),   A6IYM5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020405   ⟸   ENSRNOT00000020405
RefSeq Acc Id: XP_038953405   ⟸   XM_039097477
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000100978   ⟸   ENSRNOT00000149535
Protein Domains
Death

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZC5-F1-model_v2 AlphaFold D3ZZC5 1-310 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621313 AgrOrtholog
BioCyc Gene G2FUF-5852 BioCyc
Ensembl Genes ENSRNOG00000015179 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020405 ENTREZGENE
  ENSRNOT00000020405.8 UniProtKB/TrEMBL
  ENSRNOT00000149535.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  3.30.70.680 UniProtKB/TrEMBL
InterPro DEATH-like_dom UniProtKB/TrEMBL
  Death_domain UniProtKB/TrEMBL
  TRADD UniProtKB/TrEMBL
  TRADD_N UniProtKB/TrEMBL
  TRADD_N_sf UniProtKB/TrEMBL
KEGG Report rno:246756 UniProtKB/TrEMBL
NCBI Gene 246756 ENTREZGENE
PANTHER PTHR14913 UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN UniProtKB/TrEMBL
Pfam Death UniProtKB/TrEMBL
  TRADD_N UniProtKB/TrEMBL
PhenoGen Tradd PhenoGen
PROSITE DEATH_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015179 RatGTEx
SMART DEATH UniProtKB/TrEMBL
Superfamily-SCOP DEATH_like UniProtKB/TrEMBL
  TRADD_N UniProtKB/TrEMBL
UniProt A0ABK0LCX6_RAT UniProtKB/TrEMBL
  A6IYM5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZC5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Tradd  TNFRSF1A-associated via death domain      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Tradd  TNFRSF1A-associated via death domain      Symbol and Name status set to provisional 70820 PROVISIONAL