Ttn (titin) - Rat Genome Database

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Gene: Ttn (titin) Rattus norvegicus
Analyze
Symbol: Ttn
Name: titin
RGD ID: 621114
Description: Predicted to enable several functions, including cytoskeletal protein binding activity; enzyme binding activity; and protein kinase activity. Predicted to be a structural constituent of muscle. Involved in sarcomere organization. Located in I band. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple) and myopathy (multiple). Orthologous to human TTN (titin); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 3,3',5-triiodo-L-thyronine; acetylleucyl-leucyl-norleucinal; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: connectin; titin protein homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Ttnem1Sage ; Ttnem2Sage
Genetic Models: F344-Ttnem2Sage ; F344-Ttnem1Sage
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8382,059,648 - 82,332,130 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl382,059,648 - 82,332,171 (-)EnsemblGRCr8
mRatBN7.2361,652,432 - 61,924,912 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl361,652,439 - 61,924,741 (-)EnsemblmRatBN7.2
Rnor_6.0363,565,160 - 63,837,815 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0370,138,896 - 70,408,647 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4359,404,023 - 59,665,308 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera361,137,881 - 61,409,292 (-)NCBICelera
RGSC_v3.1359,490,644 - 59,514,338 (-)NCBI
Cytogenetic Map3q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
arrhythmogenic right ventricular cardiomyopathy  (ISO)
atrial fibrillation  (ISO)
autosomal dominant centronuclear myopathy  (ISO)
autosomal recessive centronuclear myopathy  (ISO)
autosomal recessive limb-girdle muscular dystrophy  (ISO)
autosomal recessive limb-girdle muscular dystrophy type 2B  (ISO)
autosomal recessive limb-girdle muscular dystrophy type 2J  (ISO,ISS)
Brugada syndrome  (ISO)
cardiomyopathy  (ISO)
centronuclear myopathy  (ISO)
centronuclear myopathy 1  (ISO)
centronuclear myopathy 2  (ISO)
clubfoot  (ISO)
congenital myopathy  (ISO)
congenital myopathy 1B  (ISO)
congenital myopathy 5  (ISO)
congenital structural myopathy  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
Diastolic Dysfunction  (ISO)
dilated cardiomyopathy  (ISO)
dilated cardiomyopathy 1A  (ISO)
dilated cardiomyopathy 1B  (ISO)
dilated cardiomyopathy 1G  (ISO,ISS)
dilated cardiomyopathy 1S  (ISO)
Dilated Cardiomyopathy with Left Ventricular Noncompaction  (ISO)
distal myopathy  (ISO)
familial hypertrophic cardiomyopathy  (ISO)
Gaucher's disease  (ISO)
Gaucher's disease type I  (ISO)
genetic disease  (ISO)
hypertrophic cardiomyopathy  (ISO)
hypertrophic cardiomyopathy 1  (ISO)
hypertrophic cardiomyopathy 2  (ISO)
hypertrophic cardiomyopathy 9  (ISO)
Left Ventricular Hypertrophy  (ISO)
Left Ventricular Noncompaction 2  (ISO)
long QT syndrome  (ISO)
long QT syndrome 1  (ISO)
Muscle Hypotonia  (ISO)
Muscle Weakness  (ISO)
muscular disease  (ISO)
muscular dystrophy  (ISO)
myocardial infarction  (IEP)
Myocardial Ischemia  (IDA)
myofibrillar myopathy 1  (ISO)
myofibrillar myopathy 9  (ISO)
myopathy  (ISO)
neuromuscular disease  (ISO)
orofacial cleft 1  (ISO)
restrictive cardiomyopathy  (ISO)
Romano-Ward Syndrome  (ISO)
Sudden Cardiac Death  (ISO)
sudden infant death syndrome  (ISO)
Sudden Unexpected Nocturnal Death Syndrome  (ISO)
Supraventricular Tachycardia  (ISO)
Syncope  (ISO)
systolic heart failure  (ISO)
tibial muscular dystrophy  (ISO,ISS)
tubular aggregate myopathy 1  (ISO)
Ventricular Tachycardia  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetylleucyl-leucyl-norleucinal  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
atrazine  (EXP)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Botulinum toxin type A  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
ciguatoxin CTX1B  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cylindrospermopsin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
diuron  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (ISO)
glyphosate  (EXP)
GSK-J4  (ISO)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
LY294002  (EXP)
methamphetamine  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nitrogen dioxide  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
phenethyl caffeate  (EXP)
pioglitazone  (ISO)
pirinixic acid  (ISO)
potassium cyanide  (ISO)
potassium dichromate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
spermine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
thalidomide  (ISO)
theophylline  (ISO)
titanium dioxide  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Detection of myofibrillar proteins using a step gradient minigel with an ambiguous interface. Chen SP, etal., Anal Biochem. 2005 Mar 15;338(2):270-7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Profiles of connectin (titin) in atrophied soleus muscle induced by unloading of rats. Goto K, etal., J Appl Physiol. 2003 Mar;94(3):897-902. Epub 2002 Oct 11.
4. Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts. Makarenko I, etal., Circ Res. 2004 Oct 1;95(7):708-16. Epub 2004 Sep 2.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Titin isoform switch in ischemic human heart disease. Neagoe C, etal., Circulation. 2002 Sep 10;106(11):1333-41.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Antisense oligonucleotide experiments elucidate the essential role of titin in sarcomerogenesis in adult rat cardiomyocytes in long-term culture. Person V, etal., J Cell Sci 2000 Nov;113 Pt 21:3851-9.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Structural analysis of the titin gene in hypertrophic cardiomyopathy: identification of a novel disease gene. Satoh M, etal., Biochem Biophys Res Commun. 1999 Aug 27;262(2):411-7.
14. Titin-truncating variants affect heart function in disease cohorts and the general population. Schafer S, etal., Nat Genet. 2016 Nov 21. doi: 10.1038/ng.3719.
Additional References at PubMed
PMID:7607248   PMID:7896840   PMID:9375787   PMID:9501083   PMID:9548712   PMID:9642272   PMID:9804419   PMID:9817758   PMID:11717165   PMID:11846417   PMID:11945023   PMID:12079354  
PMID:12432079   PMID:12651156   PMID:12785098   PMID:14676206   PMID:14988228   PMID:15138196   PMID:15454261   PMID:15582318   PMID:15688246   PMID:15802564   PMID:16115818   PMID:16407954  
PMID:16470334   PMID:16481394   PMID:16491431   PMID:16679402   PMID:16702235   PMID:16962974   PMID:17069849   PMID:17360664   PMID:17436058   PMID:18096819   PMID:18166625   PMID:18310072  
PMID:18519573   PMID:18528655   PMID:18765796   PMID:19056867   PMID:19150150   PMID:19260067   PMID:19850579   PMID:20799659   PMID:20968071   PMID:21041693   PMID:21703204   PMID:22105831  
PMID:22140043   PMID:22466703   PMID:23283722   PMID:23414517   PMID:23764881   PMID:24269766   PMID:25077715   PMID:25152160   PMID:25264194   PMID:25509861   PMID:26394485   PMID:26858417  
PMID:28676430   PMID:30063764   PMID:30715350   PMID:32889570   PMID:33368047   PMID:33805770   PMID:34668430   PMID:34681770   PMID:35762193   PMID:38928324   PMID:39119673  


Genomics

Comparative Map Data
Ttn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8382,059,648 - 82,332,130 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl382,059,648 - 82,332,171 (-)EnsemblGRCr8
mRatBN7.2361,652,432 - 61,924,912 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl361,652,439 - 61,924,741 (-)EnsemblmRatBN7.2
Rnor_6.0363,565,160 - 63,837,815 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0370,138,896 - 70,408,647 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4359,404,023 - 59,665,308 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera361,137,881 - 61,409,292 (-)NCBICelera
RGSC_v3.1359,490,644 - 59,514,338 (-)NCBI
Cytogenetic Map3q24NCBI
TTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382178,525,989 - 178,807,423 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2178,525,989 - 178,830,802 (-)Ensemblhg38GRCh38
GRCh372179,390,716 - 179,672,150 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362179,098,962 - 179,380,395 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2172,993,600 - 173,266,525 (-)NCBICelera
Cytogenetic Map2q31.2NCBI
HuRef2171,261,156 - 171,540,118 (-)NCBIHuRef
CHM1_12179,396,760 - 179,678,208 (-)NCBICHM1_1
T2T-CHM13v2.02179,008,783 - 179,290,485 (-)NCBIT2T-CHM13v2.0
Ttn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39276,534,324 - 76,812,901 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl276,534,324 - 76,812,891 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38276,703,980 - 76,982,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl276,703,980 - 76,982,547 (-)Ensemblmm10GRCm38
MGSCv37276,542,041 - 76,820,604 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36276,504,823 - 76,783,386 (-)NCBIMGSCv36mm8
Celera278,365,659 - 78,644,178 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map245.13NCBI
Ttn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540318,059,755 - 18,119,166 (+)Ensembl
ChiLan1.0NW_00495540318,057,344 - 18,328,389 (+)NCBIChiLan1.0ChiLan1.0
TTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21381,172,170 - 81,452,915 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B81,187,144 - 81,467,889 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B65,783,512 - 66,064,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B183,487,352 - 183,767,268 (-)NCBIPanPan1.1PanPan1.1panPan2
TTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13622,146,870 - 22,417,858 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3622,147,824 - 22,417,826 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3622,165,230 - 22,439,415 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03622,290,643 - 22,564,715 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3622,291,570 - 22,564,719 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13622,399,838 - 22,673,559 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03622,362,753 - 22,636,976 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03622,479,043 - 22,752,940 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ttn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303139,179,523 - 139,445,548 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365097,733,426 - 7,999,503 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11584,226,953 - 84,501,320 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21593,758,133 - 93,780,787 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11064,074,994 - 64,379,055 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1064,076,021 - 64,347,205 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040135,225,819 - 135,499,926 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624844484,593 - 760,155 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ttn
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1554,055,412 - 54,324,229 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ttn
2075 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)35986366387321459Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)35365182698651826Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)34887661993876619Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)34887661993876619Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)34790417292904172Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)35986366387321459Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35109256196092561Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)34865774493657744Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)33779691982796919Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)35986366383358329Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)358925062103925062Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)34865774493657744Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)35076614595766145Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)35109256196092561Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)35076614595766145Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)34865774493657744Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)37359251285062403Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)33870893183708931Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)34865774493657744Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)33736373482363734Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)34865774493657744Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
RH98821  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,675,712 - 61,675,852 (+)MAPPERmRatBN7.2
Rnor_6.0363,588,441 - 63,588,580NCBIRnor6.0
Rnor_5.0370,162,177 - 70,162,316UniSTSRnor5.0
RGSC_v3.4359,427,737 - 59,427,876UniSTSRGSC3.4
Celera361,161,160 - 61,161,299UniSTS
Cytogenetic Map3q23UniSTS
RH131516  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,862,090 - 61,862,296 (+)MAPPERmRatBN7.2
Rnor_6.0363,775,710 - 63,775,915NCBIRnor6.0
Rnor_5.0370,346,833 - 70,347,038UniSTSRnor5.0
RGSC_v3.4359,604,915 - 59,605,120UniSTSRGSC3.4
Celera361,346,433 - 61,346,638UniSTS
Cytogenetic Map3q23UniSTS
RH137063  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,652,435 - 61,652,611 (+)MAPPERmRatBN7.2
Rnor_6.0363,565,164 - 63,565,339NCBIRnor6.0
Rnor_5.0370,138,900 - 70,139,075UniSTSRnor5.0
RGSC_v3.4359,404,460 - 59,404,635UniSTSRGSC3.4
Celera361,137,885 - 61,138,060UniSTS
Cytogenetic Map3q23UniSTS
MARC_23497-23498:1027358865:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,704,263 - 61,704,930 (+)MAPPERmRatBN7.2
Rnor_6.0363,617,472 - 63,618,138NCBIRnor6.0
Rnor_5.0370,189,953 - 70,190,619UniSTSRnor5.0
Celera361,189,633 - 61,190,299UniSTS
Cytogenetic Map3q23UniSTS
D2S1570E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,724,050 - 61,724,240 (+)MAPPERmRatBN7.2
Rnor_6.0363,636,859 - 63,637,048NCBIRnor6.0
Rnor_5.0370,209,340 - 70,209,529UniSTSRnor5.0
RGSC_v3.4359,465,671 - 59,465,860UniSTSRGSC3.4
Celera361,209,377 - 61,209,566UniSTS
Cytogenetic Map3q23UniSTS


Genetic Models
This gene Ttn is modified in the following models/strains:
F344-Ttnem2Sage     F344-Ttnem1Sage    


Expression

RNA-SEQ Expression

appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
1 17 48 17 60 44 11 45 16 13 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_032068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF059344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF525411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF525412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ401157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY434474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L38717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC269844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U82224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U89530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U89531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000030978   ⟹   ENSRNOP00000033967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl382,314,277 - 82,332,171 (-)Ensembl
mRatBN7.2 Ensembl361,907,065 - 61,924,741 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101577   ⟹   ENSRNOP00000081880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl382,059,648 - 82,332,103 (-)Ensembl
mRatBN7.2 Ensembl361,652,439 - 61,924,741 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107188   ⟹   ENSRNOP00000084099
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl361,899,657 - 61,924,741 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108121   ⟹   ENSRNOP00000086880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl382,269,488 - 82,332,171 (-)Ensembl
mRatBN7.2 Ensembl361,862,276 - 61,924,741 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114553   ⟹   ENSRNOP00000082190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl382,059,648 - 82,319,546 (-)Ensembl
mRatBN7.2 Ensembl361,652,439 - 61,924,741 (-)Ensembl
RefSeq Acc Id: NM_032068   ⟹   NP_114457
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,110 (-)NCBI
RefSeq Acc Id: XM_039106384   ⟹   XP_038962312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106385   ⟹   XP_038962313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106386   ⟹   XP_038962314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106387   ⟹   XP_038962315
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106388   ⟹   XP_038962316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106389   ⟹   XP_038962317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106391   ⟹   XP_038962319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106393   ⟹   XP_038962321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106400   ⟹   XP_038962328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106402   ⟹   XP_038962330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106403   ⟹   XP_038962331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106405   ⟹   XP_038962333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106406   ⟹   XP_038962334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106407   ⟹   XP_038962335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106408   ⟹   XP_038962336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106409   ⟹   XP_038962337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106412   ⟹   XP_038962340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106413   ⟹   XP_038962341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106415   ⟹   XP_038962343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106416   ⟹   XP_038962344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106417   ⟹   XP_038962345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106418   ⟹   XP_038962346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106420   ⟹   XP_038962348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106421   ⟹   XP_038962349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106423   ⟹   XP_038962351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106424   ⟹   XP_038962352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106425   ⟹   XP_038962353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106426   ⟹   XP_038962354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106428   ⟹   XP_038962356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106429   ⟹   XP_038962357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106430   ⟹   XP_038962358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106431   ⟹   XP_038962359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106432   ⟹   XP_038962360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106433   ⟹   XP_038962361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_063284689   ⟹   XP_063140759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284690   ⟹   XP_063140760
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284691   ⟹   XP_063140761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284693   ⟹   XP_063140763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284694   ⟹   XP_063140764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284695   ⟹   XP_063140765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284696   ⟹   XP_063140766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284697   ⟹   XP_063140767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284699   ⟹   XP_063140769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284700   ⟹   XP_063140770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284701   ⟹   XP_063140771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284702   ⟹   XP_063140772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284703   ⟹   XP_063140773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284705   ⟹   XP_063140775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
RefSeq Acc Id: XM_063284706   ⟹   XP_063140776
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8382,059,648 - 82,332,130 (-)NCBI
Protein Sequences
Protein RefSeqs NP_114457 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962312 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962313 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962314 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962315 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962316 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962317 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962319 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962321 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962328 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962330 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962331 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962333 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962334 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962335 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962336 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962337 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962340 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962341 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962343 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962344 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962345 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962346 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962348 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962349 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962351 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962352 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962353 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962354 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962356 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962357 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962358 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962359 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962360 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962361 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140759 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140760 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140761 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140763 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140764 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140765 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140766 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140767 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140769 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140770 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140771 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140772 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140773 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140775 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140776 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA65720 (Get FASTA)   NCBI Sequence Viewer  
  AAC53425 (Get FASTA)   NCBI Sequence Viewer  
  AAC53426 (Get FASTA)   NCBI Sequence Viewer  
  AAD00527 (Get FASTA)   NCBI Sequence Viewer  
  AAF76252 (Get FASTA)   NCBI Sequence Viewer  
  AAP80789 (Get FASTA)   NCBI Sequence Viewer  
  AAP80790 (Get FASTA)   NCBI Sequence Viewer  
  AAS16364 (Get FASTA)   NCBI Sequence Viewer  
  AAS16365 (Get FASTA)   NCBI Sequence Viewer  
  AAS16366 (Get FASTA)   NCBI Sequence Viewer  
  AAS16367 (Get FASTA)   NCBI Sequence Viewer  
  AAS16368 (Get FASTA)   NCBI Sequence Viewer  
  AAS16369 (Get FASTA)   NCBI Sequence Viewer  
  AAS17013 (Get FASTA)   NCBI Sequence Viewer  
  BCD56193 (Get FASTA)   NCBI Sequence Viewer  
  CAB95001 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000033967.2
  ENSRNOP00000081880
  ENSRNOP00000081880.1
  ENSRNOP00000082190
  ENSRNOP00000082190.2
  ENSRNOP00000086880.1
RefSeq Acc Id: XP_038962321   ⟸   XM_039106393
- Peptide Label: isoform X12
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962319   ⟸   XM_039106391
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962361   ⟸   XM_039106433
- Peptide Label: isoform X49
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962360   ⟸   XM_039106432
- Peptide Label: isoform X48
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962359   ⟸   XM_039106431
- Peptide Label: isoform X47
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962358   ⟸   XM_039106430
- Peptide Label: isoform X46
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962357   ⟸   XM_039106429
- Peptide Label: isoform X45
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962356   ⟸   XM_039106428
- Peptide Label: isoform X44
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962317   ⟸   XM_039106389
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962315   ⟸   XM_039106387
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962354   ⟸   XM_039106426
- Peptide Label: isoform X42
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962349   ⟸   XM_039106421
- Peptide Label: isoform X35
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962345   ⟸   XM_039106417
- Peptide Label: isoform X29
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962340   ⟸   XM_039106412
- Peptide Label: isoform X24
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962335   ⟸   XM_039106407
- Peptide Label: isoform X21
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962353   ⟸   XM_039106425
- Peptide Label: isoform X41
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962348   ⟸   XM_039106420
- Peptide Label: isoform X33
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962343   ⟸   XM_039106415
- Peptide Label: isoform X26
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962336   ⟸   XM_039106408
- Peptide Label: isoform X22
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962334   ⟸   XM_039106406
- Peptide Label: isoform X20
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962352   ⟸   XM_039106424
- Peptide Label: isoform X38
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962346   ⟸   XM_039106418
- Peptide Label: isoform X31
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962341   ⟸   XM_039106413
- Peptide Label: isoform X25
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962333   ⟸   XM_039106405
- Peptide Label: isoform X19
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962330   ⟸   XM_039106402
- Peptide Label: isoform X17
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962351   ⟸   XM_039106423
- Peptide Label: isoform X37
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962344   ⟸   XM_039106416
- Peptide Label: isoform X28
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962337   ⟸   XM_039106409
- Peptide Label: isoform X23
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962331   ⟸   XM_039106403
- Peptide Label: isoform X18
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962328   ⟸   XM_039106400
- Peptide Label: isoform X16
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962314   ⟸   XM_039106386
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962316   ⟸   XM_039106388
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962312   ⟸   XM_039106384
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962313   ⟸   XM_039106385
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000084099   ⟸   ENSRNOT00000107188
Ensembl Acc Id: ENSRNOP00000082190   ⟸   ENSRNOT00000114553
Ensembl Acc Id: ENSRNOP00000086880   ⟸   ENSRNOT00000108121
Ensembl Acc Id: ENSRNOP00000033967   ⟸   ENSRNOT00000030978
Ensembl Acc Id: ENSRNOP00000081880   ⟸   ENSRNOT00000101577
RefSeq Acc Id: XP_063140776   ⟸   XM_063284706
- Peptide Label: isoform X43
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140759   ⟸   XM_063284689
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140775   ⟸   XM_063284705
- Peptide Label: isoform X40
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140773   ⟸   XM_063284703
- Peptide Label: isoform X39
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140771   ⟸   XM_063284701
- Peptide Label: isoform X34
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140772   ⟸   XM_063284702
- Peptide Label: isoform X36
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140769   ⟸   XM_063284699
- Peptide Label: isoform X30
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140770   ⟸   XM_063284700
- Peptide Label: isoform X32
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140767   ⟸   XM_063284697
- Peptide Label: isoform X27
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140766   ⟸   XM_063284696
- Peptide Label: isoform X15
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140765   ⟸   XM_063284695
- Peptide Label: isoform X14
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140763   ⟸   XM_063284693
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140761   ⟸   XM_063284691
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140760   ⟸   XM_063284690
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140764   ⟸   XM_063284694
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_114457   ⟸   NM_032068
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
Protein Domains
Fibronectin type-III   Ig-like   Immunoglobulin I-set   Protein kinase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621114 AgrOrtholog
BioCyc Gene G2FUF-49275 BioCyc
Ensembl Genes ENSRNOG00000069271 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030978.4 UniProtKB/TrEMBL
  ENSRNOT00000101577 ENTREZGENE
  ENSRNOT00000101577.2 UniProtKB/TrEMBL
  ENSRNOT00000108121.2 UniProtKB/TrEMBL
  ENSRNOT00000114553 ENTREZGENE
  ENSRNOT00000114553.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Cell_Adh-Cytoskel_Orgn UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  MyBP-C_THB UniProtKB/TrEMBL
  PPAK_motif UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Titin_Z_rpt UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
NCBI Gene 84015 ENTREZGENE
PANTHER CONTACTIN 5 UniProtKB/TrEMBL
  IMMUNOGLOBULIN UniProtKB/TrEMBL
  LP07818P1 UniProtKB/TrEMBL
  OS12G0136300 PROTEIN UniProtKB/TrEMBL
  PTHR14340 UniProtKB/TrEMBL
  STRIATED MUSCLE PREFERENTIALLY EXPRESSED PROTEIN KINASE UniProtKB/TrEMBL
  TITIN UniProtKB/TrEMBL
  WRAPPER_REGA-1_KLINGON HOMOLOG UniProtKB/TrEMBL
Pfam fn3; 132 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
  PPAK UniProtKB/TrEMBL
  THB UniProtKB/TrEMBL
  Titin_Z UniProtKB/TrEMBL
PhenoGen Ttn PhenoGen
PRINTS FNTYPEIII UniProtKB/TrEMBL
  PRICHEXTENSN UniProtKB/TrEMBL
PROSITE FN3; 132 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000069271 RatGTEx
SMART FN3; 132 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A8I5ZU83_RAT UniProtKB/TrEMBL
  A0A8I5ZUN3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A794_RAT UniProtKB/TrEMBL
  D4A8Y1_RAT UniProtKB/TrEMBL
  Q5VJM3_RAT UniProtKB/TrEMBL
  Q5VJM4_RAT UniProtKB/TrEMBL
  Q5VJM5_RAT UniProtKB/TrEMBL
  Q5VJM6_RAT UniProtKB/TrEMBL
  Q5VJM7_RAT UniProtKB/TrEMBL
  Q9JHQ1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Ttn  titin  Ttn  titin  Data merged from RGD:149736286 737654 PROVISIONAL
2021-08-09 Ttn  titin      Symbol and Name status set to provisional 45752 PROVISIONAL
2004-09-10 Ttn  titin      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Ttn  titin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function acts as a template for myosin incorporation into thick filaments 634444