Symbol:
Ttn
Name:
titin
RGD ID:
621114
Description:
Predicted to enable several functions, including cytoskeletal protein binding activity; enzyme binding activity; and protein kinase activity. Predicted to be a structural constituent of muscle. Involved in sarcomere organization. Located in I band. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple) and myopathy (multiple). Orthologous to human TTN (titin); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 3,3',5-triiodo-L-thyronine; acetylleucyl-leucyl-norleucinal; acrylamide.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
connectin; titin protein homolog
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
TTN (titin) RGD
RGD
Mus musculus (house mouse):
Ttn (titin) RGD
RGD
Chinchilla lanigera (long-tailed chinchilla):
Ttn (titin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
TTN (titin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
TTN (titin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Ttn (titin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
TTN (titin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
TTN (titin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Ttn (titin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
TTN (titin)
Alliance
DIOPT (HGNC)
Allele / Splice:
Ttnem1Sage
Ttnem2Sage
Genetic Models:
F344-Ttnem2Sage
F344-Ttnem1Sage
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 82,059,648 - 82,332,130 (-) NCBI GRCr8 mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 61,652,439 - 61,924,741 (-) Ensembl mRatBN7.2 Ensembl Rnor_6.0 3 63,565,160 - 63,837,815 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_5.0 3 70,138,896 - 70,408,647 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 59,404,023 - 59,665,308 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 3 59,490,644 - 59,514,338 (-) NCBI Celera 3 61,137,881 - 61,409,292 (-) NCBI Celera Cytogenetic Map 3 q24 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Ttn Rat 1,2-dichloroethane decreases expression ISO Ttn (Mus musculus) 6480464 ethylene dichloride results in decreased expression of TTN mRNA CTD PMID:28960355 Ttn Rat 1,2-dimethylhydrazine decreases expression ISO Ttn (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of TTN mRNA CTD PMID:22206623 Ttn Rat 17beta-estradiol decreases expression ISO Ttn (Mus musculus) 6480464 Estradiol results in decreased expression of TTN mRNA CTD PMID:19484750 and PMID:25210133 Ttn Rat 17beta-estradiol increases expression ISO Ttn (Mus musculus) 6480464 Estradiol results in increased expression of TTN mRNA CTD PMID:39298647 Ttn Rat 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO TTN (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of TTN mRNA CTD PMID:29581250 Ttn Rat 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO TTN (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 Ttn Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ttn (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of TTN mRNA CTD PMID:21889950 Ttn Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Ttn (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Ttn Rat 3,3',5-triiodo-L-thyronine multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine affects the expression of TTN mRNA] and AKT1 protein affects the reaction [Triiodothyronine affects the expression of TTN mRNA] CTD PMID:18096819 Ttn Rat 3,3',5-triiodo-L-thyronine affects expression EXP 6480464 Triiodothyronine affects the expression of TTN mRNA CTD PMID:18096819 Ttn Rat 3,4-methylenedioxymethamphetamine decreases expression ISO Ttn (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TTN mRNA CTD PMID:26251327 Ttn Rat 3,4-methylenedioxymethamphetamine affects methylation ISO Ttn (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine affects the methylation of TTN promoter CTD PMID:26251327 Ttn Rat 3-phenylprop-2-enal decreases expression ISO TTN (Homo sapiens) 6480464 cinnamaldehyde results in decreased expression of TTN mRNA CTD PMID:19000754 Ttn Rat 4,4'-sulfonyldiphenol increases expression ISO Ttn (Mus musculus) 6480464 bisphenol S results in increased expression of TTN mRNA CTD PMID:30951980 Ttn Rat 4,4'-sulfonyldiphenol decreases methylation ISO Ttn (Mus musculus) 6480464 bisphenol S results in decreased methylation of TTN exon and bisphenol S results in decreased methylation of TTN promoter CTD PMID:33297965 Ttn Rat acetylleucyl-leucyl-norleucinal multiple interactions EXP 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [Doxorubicin results in increased degradation of TTN protein] CTD PMID:22532871 Ttn Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of TTN mRNA CTD PMID:22197712 Ttn Rat acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of TTN mRNA CTD PMID:28959563 Ttn Rat aflatoxin B1 decreases methylation ISO TTN (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of TTN gene CTD PMID:27153756 Ttn Rat aflatoxin B1 increases methylation ISO TTN (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of TTN exon CTD PMID:30157460 Ttn Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TTN mRNA CTD PMID:16483693 Ttn Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of TTN gene CTD PMID:35440735 Ttn Rat Azoxymethane multiple interactions ISO Ttn (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TTN mRNA CTD PMID:29950665 Ttn Rat benzo[a]pyrene increases mutagenesis ISO TTN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased mutagenesis of TTN gene CTD PMID:25435355 Ttn Rat benzo[a]pyrene decreases expression ISO TTN (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of TTN mRNA CTD PMID:32234424 Ttn Rat benzo[a]pyrene affects methylation ISO TTN (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of TTN promoter CTD PMID:27901495 Ttn Rat benzo[a]pyrene increases methylation ISO Ttn (Mus musculus) 6480464 Benzo(a)pyrene results in increased methylation of TTN exon and Benzo(a)pyrene results in increased methylation of TTN intron CTD PMID:27901495 Ttn Rat benzo[a]pyrene increases expression ISO Ttn (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of TTN mRNA CTD PMID:22228805 Ttn Rat benzo[a]pyrene decreases expression ISO Ttn (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of TTN mRNA CTD PMID:22228805 Ttn Rat benzo[b]fluoranthene decreases expression ISO Ttn (Mus musculus) 6480464 benzo(b)fluoranthene results in decreased expression of TTN mRNA CTD PMID:26377693 Ttn Rat bis(2-ethylhexyl) phthalate decreases expression ISO Ttn (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of TTN mRNA CTD PMID:33754040 Ttn Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TTN mRNA CTD PMID:27178563 Ttn Rat bisphenol A increases expression ISO TTN (Homo sapiens) 6480464 bisphenol A results in increased expression of TTN protein CTD PMID:37567409 Ttn Rat bisphenol A decreases expression ISO Ttn (Mus musculus) 6480464 bisphenol A results in decreased expression of TTN mRNA CTD PMID:32156529 Ttn Rat bisphenol A decreases expression ISO TTN (Homo sapiens) 6480464 bisphenol A results in decreased expression of TTN protein CTD PMID:31675489 Ttn Rat bisphenol A increases expression ISO Ttn (Mus musculus) 6480464 bisphenol A results in increased expression of TTN mRNA CTD PMID:30951980 Ttn Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of TTN mRNA CTD PMID:25181051 Ttn Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TTN mRNA CTD PMID:18180321 Ttn Rat bisphenol F increases expression ISO Ttn (Mus musculus) 6480464 bisphenol F results in increased expression of TTN mRNA CTD PMID:30951980 Ttn Rat Botulinum toxin type A decreases expression EXP 6480464 Botulinum Toxins and Type A results in decreased expression of TTN protein CTD PMID:19260067 Ttn Rat Botulinum toxin type A increases expression EXP 6480464 Botulinum Toxins and Type A results in increased expression of TTN mRNA CTD PMID:18603602 Ttn Rat cadmium atom multiple interactions ISO Ttn (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TTN mRNA CTD PMID:37325564 Ttn Rat cadmium dichloride multiple interactions ISO Ttn (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TTN mRNA CTD PMID:37325564 Ttn Rat caffeine affects phosphorylation ISO TTN (Homo sapiens) 6480464 Caffeine affects the phosphorylation of TTN protein CTD PMID:35688186 Ttn Rat cantharidin decreases expression ISO Ttn (Mus musculus) 6480464 Cantharidin results in decreased expression of TTN mRNA CTD PMID:36907384 Ttn Rat carbon nanotube affects expression ISO Ttn (Mus musculus) 6480464 Nanotubes more ... CTD PMID:21135415 and PMID:25554681 Ttn Rat carbon nanotube increases expression ISO Ttn (Mus musculus) 6480464 Nanotubes and Carbon results in increased expression of TTN mRNA CTD PMID:25620056 Ttn Rat carbon nanotube decreases expression ISO Ttn (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 Ttn Rat CGP 52608 multiple interactions ISO TTN (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to TTN gene] CTD PMID:28238834 Ttn Rat ciguatoxin CTX1B affects expression ISO Ttn (Mus musculus) 6480464 Ciguatoxins affects the expression of TTN mRNA CTD PMID:18353800 Ttn Rat copper(II) sulfate increases expression ISO TTN (Homo sapiens) 6480464 Copper Sulfate results in increased expression of TTN mRNA CTD PMID:19549813 Ttn Rat coumarin increases phosphorylation ISO TTN (Homo sapiens) 6480464 coumarin results in increased phosphorylation of TTN protein CTD PMID:35688186 Ttn Rat cylindrospermopsin decreases expression ISO TTN (Homo sapiens) 6480464 cylindrospermopsin results in decreased expression of TTN mRNA CTD PMID:24921660 Ttn Rat dexamethasone increases expression ISO Ttn (Mus musculus) 6480464 Dexamethasone results in increased expression of TTN mRNA CTD PMID:22733784 Ttn Rat dextran sulfate multiple interactions ISO Ttn (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TTN mRNA CTD PMID:29950665 Ttn Rat Dibutyl phosphate affects expression ISO TTN (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of TTN mRNA CTD PMID:37042841 Ttn Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of TTN mRNA CTD PMID:21266533 Ttn Rat dimethylarsinic acid increases expression ISO Ttn (Mus musculus) 6480464 Cacodylic Acid results in increased expression of TTN mRNA CTD PMID:17441966 Ttn Rat dioxygen multiple interactions ISO Ttn (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TTN mRNA and [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TTN mRNA CTD PMID:19640911 and PMID:30529165 Ttn Rat dioxygen increases expression ISO TTN (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of TTN mRNA CTD PMID:35883890 Ttn Rat diuron decreases expression ISO TTN (Homo sapiens) 6480464 Diuron results in decreased expression of TTN mRNA CTD PMID:35967413 Ttn Rat doxorubicin multiple interactions EXP 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [Doxorubicin results in increased degradation of TTN protein] CTD PMID:22532871 Ttn Rat doxorubicin decreases expression ISO TTN (Homo sapiens) 6480464 Doxorubicin results in decreased expression of TTN mRNA CTD PMID:29803840 Ttn Rat doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of TTN mRNA CTD PMID:22532871 Ttn Rat doxorubicin increases degradation EXP 6480464 Doxorubicin results in increased degradation of TTN protein CTD PMID:22532871 Ttn Rat entinostat decreases expression ISO TTN (Homo sapiens) 6480464 entinostat results in decreased expression of TTN mRNA CTD PMID:27188386 Ttn Rat glyphosate affects methylation EXP 6480464 Glyphosate affects the methylation of TTN gene CTD PMID:35440735 Ttn Rat hydrogen cyanide increases expression ISO Ttn (Mus musculus) 6480464 Hydrogen Cyanide results in increased expression of TTN mRNA CTD PMID:33914522 Ttn Rat hydrogen peroxide multiple interactions ISO TTN (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TTN protein CTD PMID:18951874 Ttn Rat ivermectin decreases expression ISO TTN (Homo sapiens) 6480464 Ivermectin results in decreased expression of TTN protein CTD PMID:32959892 Ttn Rat lipopolysaccharide multiple interactions ISO TTN (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 Ttn Rat LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine affects the expression of TTN mRNA] CTD PMID:18096819 Ttn Rat methamphetamine increases expression ISO Ttn (Mus musculus) 6480464 Methamphetamine results in increased expression of TTN mRNA CTD PMID:26307267 Ttn Rat methylmercury chloride decreases expression ISO TTN (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of TTN mRNA CTD PMID:28001369 Ttn Rat microcystin-LR increases expression ISO TTN (Homo sapiens) 6480464 cyanoginosin LR results in increased expression of TTN mRNA CTD PMID:29518473 Ttn Rat microcystin-LR increases expression ISO Ttn (Mus musculus) 6480464 cyanoginosin LR results in increased expression of TTN mRNA CTD PMID:37342990 Ttn Rat mono(2-ethylhexyl) phthalate increases expression ISO Ttn (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of TTN mRNA CTD PMID:22401849 Ttn Rat N-methyl-4-phenylpyridinium increases expression ISO Ttn (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of TTN protein CTD PMID:26558463 Ttn Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TTN mRNA CTD PMID:20360939 Ttn Rat nickel atom increases expression ISO TTN (Homo sapiens) 6480464 Nickel results in increased expression of TTN mRNA CTD PMID:24768652 Ttn Rat nitrogen dioxide increases expression ISO TTN (Homo sapiens) 6480464 Nitrogen Dioxide results in increased expression of TTN mRNA CTD PMID:27206323 Ttn Rat O-methyleugenol decreases expression ISO TTN (Homo sapiens) 6480464 methyleugenol results in decreased expression of TTN mRNA CTD PMID:32234424 Ttn Rat paracetamol affects expression ISO Ttn (Mus musculus) 6480464 Acetaminophen affects the expression of TTN mRNA CTD PMID:17562736 Ttn Rat phenethyl caffeate multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TTN mRNA CTD PMID:20360939 Ttn Rat pioglitazone multiple interactions ISO Ttn (Mus musculus) 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TTN mRNA CTD PMID:27935865 Ttn Rat pirinixic acid increases expression ISO Ttn (Mus musculus) 6480464 pirinixic acid results in increased expression of TTN mRNA CTD PMID:20813756 Ttn Rat potassium cyanide increases expression ISO Ttn (Mus musculus) 6480464 Potassium Cyanide results in increased expression of TTN mRNA CTD PMID:33914522 Ttn Rat potassium dichromate decreases expression ISO Ttn (Mus musculus) 6480464 Potassium Dichromate results in decreased expression of TTN mRNA CTD PMID:23608068 Ttn Rat propiconazole decreases expression ISO Ttn (Mus musculus) 6480464 propiconazole results in decreased expression of TTN mRNA CTD PMID:21278054 Ttn Rat quercetin decreases expression ISO TTN (Homo sapiens) 6480464 Quercetin results in decreased expression of TTN protein CTD PMID:19207037 Ttn Rat resveratrol decreases expression ISO Ttn (Mus musculus) 6480464 resveratrol results in decreased expression of TTN mRNA CTD PMID:22610192 Ttn Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO TTN (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 Ttn Rat serpentine asbestos increases methylation ISO TTN (Homo sapiens) 6480464 Asbestos and Serpentine results in increased methylation of TTN 5' UTR CTD PMID:29523930 Ttn Rat sodium arsenite increases expression ISO TTN (Homo sapiens) 6480464 sodium arsenite results in increased expression of TTN mRNA CTD PMID:28229933 and PMID:38568856 Ttn Rat sodium arsenite decreases expression ISO Ttn (Mus musculus) 6480464 sodium arsenite results in decreased expression of TTN mRNA CTD PMID:36209798 Ttn Rat sodium arsenite multiple interactions ISO TTN (Homo sapiens) 6480464 sodium arsenite promotes the reaction [TTN protein binds to CAPRIN1 protein] CTD PMID:33939924 Ttn Rat sodium arsenite decreases expression ISO TTN (Homo sapiens) 6480464 sodium arsenite results in decreased expression of TTN mRNA CTD PMID:29301061 Ttn Rat sodium fluoride decreases expression ISO Ttn (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of TTN mRNA CTD PMID:27862939 Ttn Rat spermine increases expression ISO Ttn (Mus musculus) 6480464 Spermine results in increased expression of TTN mRNA CTD PMID:18673383 Ttn Rat sulforaphane increases expression ISO Ttn (Mus musculus) 6480464 sulforaphane results in increased expression of TTN mRNA CTD PMID:30529165 Ttn Rat sunitinib increases expression ISO TTN (Homo sapiens) 6480464 Sunitinib results in increased expression of TTN mRNA CTD PMID:31533062 Ttn Rat T-2 toxin decreases expression ISO TTN (Homo sapiens) 6480464 T-2 Toxin results in decreased expression of TTN mRNA CTD PMID:34581912 Ttn Rat thalidomide decreases expression ISO Ttn (Mus musculus) 6480464 Thalidomide results in decreased expression of TTN mRNA CTD PMID:26006729 and PMID:26217789 Ttn Rat theophylline multiple interactions ISO TTN (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of TTN protein CTD PMID:18951874 Ttn Rat titanium dioxide decreases expression ISO Ttn (Mus musculus) 6480464 titanium dioxide results in decreased expression of TTN mRNA CTD PMID:23557971 and PMID:35295148 Ttn Rat titanium dioxide multiple interactions ISO Ttn (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TTN mRNA CTD PMID:29950665 Ttn Rat triclosan decreases expression ISO TTN (Homo sapiens) 6480464 Triclosan results in decreased expression of TTN mRNA CTD PMID:30510588 Ttn Rat triphenyl phosphate affects expression ISO TTN (Homo sapiens) 6480464 triphenyl phosphate affects the expression of TTN mRNA CTD PMID:37042841 Ttn Rat triptonide increases expression ISO Ttn (Mus musculus) 6480464 triptonide results in increased expression of TTN mRNA CTD PMID:33045310 Ttn Rat valproic acid decreases methylation ISO TTN (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of TTN gene CTD PMID:29154799
Imported Annotations - KEGG (archival)
1,2-dichloroethane (ISO) 1,2-dimethylhydrazine (ISO) 17beta-estradiol (ISO) 17beta-hydroxy-5alpha-androstan-3-one (ISO) 2,2',4,4'-Tetrabromodiphenyl ether (ISO) 2,3,7,8-tetrachlorodibenzodioxine (ISO) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 3,3',5-triiodo-L-thyronine (EXP) 3,4-methylenedioxymethamphetamine (ISO) 3-phenylprop-2-enal (ISO) 4,4'-sulfonyldiphenol (ISO) acetylleucyl-leucyl-norleucinal (EXP) acrylamide (EXP) aflatoxin B1 (ISO) ammonium chloride (EXP) atrazine (EXP) Azoxymethane (ISO) benzo[a]pyrene (ISO) benzo[b]fluoranthene (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol F (ISO) Botulinum toxin type A (EXP) cadmium atom (ISO) cadmium dichloride (ISO) caffeine (ISO) cantharidin (ISO) carbon nanotube (ISO) CGP 52608 (ISO) ciguatoxin CTX1B (ISO) copper(II) sulfate (ISO) coumarin (ISO) cylindrospermopsin (ISO) dexamethasone (ISO) dextran sulfate (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (EXP) dimethylarsinic acid (ISO) dioxygen (ISO) diuron (ISO) doxorubicin (EXP,ISO) entinostat (ISO) glyphosate (EXP) hydrogen cyanide (ISO) hydrogen peroxide (ISO) ivermectin (ISO) lipopolysaccharide (ISO) LY294002 (EXP) methamphetamine (ISO) methylmercury chloride (ISO) microcystin-LR (ISO) mono(2-ethylhexyl) phthalate (ISO) N-methyl-4-phenylpyridinium (ISO) N-nitrosodiethylamine (EXP) nickel atom (ISO) nitrogen dioxide (ISO) O-methyleugenol (ISO) paracetamol (ISO) phenethyl caffeate (EXP) pioglitazone (ISO) pirinixic acid (ISO) potassium cyanide (ISO) potassium dichromate (ISO) propiconazole (ISO) quercetin (ISO) resveratrol (ISO) S-(1,2-dichlorovinyl)-L-cysteine (ISO) serpentine asbestos (ISO) sodium arsenite (ISO) sodium fluoride (ISO) spermine (ISO) sulforaphane (ISO) sunitinib (ISO) T-2 toxin (ISO) thalidomide (ISO) theophylline (ISO) titanium dioxide (ISO) triclosan (ISO) triphenyl phosphate (ISO) triptonide (ISO) valproic acid (ISO)
1.
Detection of myofibrillar proteins using a step gradient minigel with an ambiguous interface.
Chen SP, etal., Anal Biochem. 2005 Mar 15;338(2):270-7.
2.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.
Profiles of connectin (titin) in atrophied soleus muscle induced by unloading of rats.
Goto K, etal., J Appl Physiol. 2003 Mar;94(3):897-902. Epub 2002 Oct 11.
4.
Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts.
Makarenko I, etal., Circ Res. 2004 Oct 1;95(7):708-16. Epub 2004 Sep 2.
5.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.
Titin isoform switch in ischemic human heart disease.
Neagoe C, etal., Circulation. 2002 Sep 10;106(11):1333-41.
7.
OMIM Disease Annotation Pipeline
OMIM Disease Annotation Pipeline
8.
Antisense oligonucleotide experiments elucidate the essential role of titin in sarcomerogenesis in adult rat cardiomyocytes in long-term culture.
Person V, etal., J Cell Sci 2000 Nov;113 Pt 21:3851-9.
9.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
10.
GOA pipeline
RGD automated data pipeline
11.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
13.
Structural analysis of the titin gene in hypertrophic cardiomyopathy: identification of a novel disease gene.
Satoh M, etal., Biochem Biophys Res Commun. 1999 Aug 27;262(2):411-7.
14.
Titin-truncating variants affect heart function in disease cohorts and the general population.
Schafer S, etal., Nat Genet. 2016 Nov 21. doi: 10.1038/ng.3719.
Ttn Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 82,059,648 - 82,332,130 (-) NCBI GRCr8 mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 61,652,439 - 61,924,741 (-) Ensembl mRatBN7.2 Ensembl Rnor_6.0 3 63,565,160 - 63,837,815 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_5.0 3 70,138,896 - 70,408,647 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 59,404,023 - 59,665,308 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 3 59,490,644 - 59,514,338 (-) NCBI Celera 3 61,137,881 - 61,409,292 (-) NCBI Celera Cytogenetic Map 3 q24 NCBI
TTN Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 2 178,525,989 - 178,807,423 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 2 178,525,989 - 178,830,802 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 2 179,390,716 - 179,672,150 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 2 179,098,962 - 179,380,395 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 2 172,993,600 - 173,266,525 (-) NCBI Celera Cytogenetic Map 2 q31.2 NCBI HuRef 2 171,261,156 - 171,540,118 (-) NCBI HuRef CHM1_1 2 179,396,760 - 179,678,208 (-) NCBI CHM1_1 T2T-CHM13v2.0 2 179,008,783 - 179,290,485 (-) NCBI T2T-CHM13v2.0
Ttn Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 2 76,534,324 - 76,812,901 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 2 76,534,324 - 76,812,891 (-) Ensembl GRCm39 Ensembl GRCm38 2 76,703,980 - 76,982,557 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 2 76,703,980 - 76,982,547 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 2 76,542,041 - 76,820,604 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 2 76,504,823 - 76,783,386 (-) NCBI MGSCv36 mm8 Celera 2 78,365,659 - 78,644,178 (-) NCBI Celera Cytogenetic Map 2 C3 NCBI cM Map 2 45.13 NCBI
Ttn Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 NW_004955403 18,057,344 - 18,328,389 (+) NCBI ChiLan1.0 ChiLan1.0
TTN Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 13 81,172,170 - 81,452,915 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 2B 81,187,144 - 81,467,889 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 2B 65,783,512 - 66,064,618 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 2B 183,487,352 - 183,767,268 (-) NCBI panpan1.1 PanPan1.1 panPan2
TTN Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 36 22,146,870 - 22,417,858 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 36 22,147,824 - 22,417,826 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 36 22,165,230 - 22,439,415 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 36 22,290,643 - 22,564,715 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 36 22,291,570 - 22,564,719 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 36 22,399,838 - 22,673,559 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 36 22,362,753 - 22,636,976 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 36 22,479,043 - 22,752,940 (-) NCBI UU_Cfam_GSD_1.0
Ttn
TTN
TTN Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 10 64,074,994 - 64,379,055 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 10 64,076,021 - 64,347,205 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666040 135,225,819 - 135,499,926 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Ttn
.
1582238 Bw68 Body weight QTL 68 3.2 0.0064 body mass (VT:0001259) body weight (CMO:0000012) 3 53184593 115665732 Rat 1582239 Epfw1 Epididymal fat weight QTL 1 4.5 0.0006 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 3 53184593 115665732 Rat 2298542 Neuinf11 Neuroinflammation QTL 11 3.9 nervous system integrity trait (VT:0010566) spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126) 3 15005422 76927699 Rat 1358362 Srcrt2 Stress Responsive Cort QTL 2 2.78 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 3 38192233 133483320 Rat 737818 Hcar12 Hepatocarcinoma resistance QTL 12 2.6 liver integrity trait (VT:0010547) volume of individual liver tumorous lesion (CMO:0001078) 3 29463235 118376539 Rat 1582218 Bw74 Body weight QTL 74 3.9 0.0021 body mass (VT:0001259) body weight (CMO:0000012) 3 53184593 115665732 Rat 1581568 Rf53 Renal function QTL 53 urine total protein amount (VT:0000032) urine protein excretion rate to body weight ratio (CMO:0001099) 3 56395968 161299569 Rat 9590286 Uminl1 Urine mineral level QTL 1 3.5 0.001 urine mineral amount (VT:0015086) urine electrolyte level (CMO:0000593) 3 28249687 73249687 Rat 1300111 Rf12 Renal function QTL 12 3.78 renal blood flow trait (VT:2000006) absolute change in renal blood flow rate (CMO:0001168) 3 61017749 121056321 Rat 724523 Tsu1 Thymus enlargement suppressive QTL 1 3.84 thymus mass (VT:0004954) thymus weight to body weight ratio (CMO:0000612) 3 50437504 115638231 Rat 8662816 Vetf4 Vascular elastic tissue fragility QTL 4 4 renal artery integrity trait (VT:0010642) number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563) 3 59242096 157323038 Rat 1581503 Cm58 Cardiac mass QTL 58 2.7 0.05 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 3 43827364 121056321 Rat 2292613 Ept16 Estrogen-induced pituitary tumorigenesis QTL 16 8.3 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 3 47233430 110362260 Rat 731180 Bp152 Blood pressure QTL 152 0.03 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 53781112 91609953 Rat 631200 Cm25 Cardiac mass QTL 25 4.8 0.0001 heart left ventricle mass (VT:0007031) heart left ventricle wet weight (CMO:0000071) 3 61134348 89115068 Rat 61356 Bp37 Blood pressure QTL 37 3 blood pressure trait (VT:0000183) systolic blood pressure (CMO:0000004) 3 30684642 75684642 Rat 1358905 Hrtrt17 Heart rate QTL 17 5.9 0.000014 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 3 10861912 89878372 Rat 8694196 Abfw2 Abdominal fat weight QTL 2 16.58 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 3 28249687 73249687 Rat 2301971 Cm71 Cardiac mass QTL 71 4.63 heart left ventricle mass (VT:0007031) heart left ventricle weight (CMO:0000776) 3 41874578 155617519 Rat 1358885 Bp251 Blood pressure QTL 251 3.8 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 14489145 121056321 Rat 2301970 Bw81 Body weight QTL 81 5.19 body mass (VT:0001259) body weight (CMO:0000012) 3 41874578 155617519 Rat 1582249 Bw77 Body weight QTL 77 3.2 0.0025 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 3 53184593 64655484 Rat 2290452 Scl56 Serum cholesterol level QTL 56 2.26 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 3 1 91609953 Rat 12879868 Am6 Aortic mass QTL 6 0.001 aorta mass (VT:0002845) aorta weight to aorta length to body weight ratio (CMO:0002722) 3 31426403 70668733 Rat 11565451 Bw177 Body weight QTL 177 0.002 body mass (VT:0001259) body weight (CMO:0000012) 3 31426403 70668733 Rat 1358888 Bp264 Blood pressure QTL 264 4.43 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 14489145 121056321 Rat 11565452 Kidm57 Kidney mass QTL 57 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 3 31426403 70668733 Rat 12879866 Cm94 Cardiac mass QTL 94 0.001 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 3 31426403 70668733 Rat 12879867 Cm95 Cardiac mass QTL 95 0.047 heart right ventricle mass (VT:0007033) heart right ventricle weight to body weight ratio (CMO:0000914) 3 31426403 70668733 Rat 1300178 Hrtrt4 Heart rate QTL 4 3.74 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 3 43827364 90905114 Rat 61377 Edpm3 Estrogen-dependent pituitary mass QTL 3 7.05 0.038 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 3 53184692 89878207 Rat 2302055 Pia30 Pristane induced arthritis QTL 30 3.5 0.001 blood autoantibody amount (VT:0003725) serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111) 3 27936919 72936919 Rat 1331795 Rf30 Renal function QTL 30 3.708 urine potassium amount (VT:0010539) urine potassium level (CMO:0000128) 3 39454637 89115240 Rat 70216 Cm14 Cardiac mass QTL 14 2.1 heart mass (VT:0007028) heart wet weight (CMO:0000069) 3 31172320 163586636 Rat 1354589 Bw31 Body weight QTL 31 3.3 body mass (VT:0001259) body weight (CMO:0000012) 3 33703347 78196190 Rat 2303593 Gluco46 Glucose level QTL 46 3 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 3 28468571 73468571 Rat 1354590 Despr11 Despair related QTL 11 0.000031 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 3 28468571 73468571 Rat 2292591 Esta4 Estrogen-induced thymic atrophy QTL 4 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 3 47233211 147415807 Rat 1331777 Bw24 Body weight QTL 24 3.503 body mass (VT:0001259) body weight (CMO:0000012) 3 39454637 89115240 Rat 631647 Bp122 Blood pressure QTL 122 6.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 30684642 75684642 Rat 1559282 Emca5 Estrogen-induced mammary cancer QTL 5 3.9 mammary gland integrity trait (VT:0010552) percentage of study population developing mammary tumors during a period of time (CMO:0000948) 3 43827364 169034231 Rat 2302276 Bw82 Body weight QTL 82 4.32 body mass (VT:0001259) body weight (CMO:0000012) 3 39454637 62951183 Rat 738019 Anxrr10 Anxiety related response QTL 10 3.9 exploratory behavior trait (VT:0010471) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 3 38517803 83517803 Rat 9590136 Scort3 Serum corticosterone level QTL 3 23.37 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 3 28249687 73249687 Rat 10450804 Scl70 Serum cholesterol level QTL 70 4.7 0.001 blood LDL cholesterol amount (VT:0000181) blood low density lipoprotein cholesterol level (CMO:0000053) 3 20714090 65714090 Rat 61419 Cia11 Collagen induced arthritis QTL 11 5.6 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 3 30356773 98535386 Rat 1354597 Kidm13 Kidney mass QTL 13 2.9 kidney mass (VT:0002707) right kidney wet weight (CMO:0000082) 3 41874578 104104347 Rat 8552950 Pigfal12 Plasma insulin-like growth factor 1 level QTL 12 7.3 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 3 28249687 73249687 Rat 631676 Cm8 Cardiac mass QTL 8 7.03 0.0001 aorta mass (VT:0002845) aorta weight (CMO:0000076) 3 16954708 61954708 Rat 10450794 Scl69 Serum cholesterol level QTL 69 6.3 0.001 blood LDL cholesterol amount (VT:0000181) blood low density lipoprotein cholesterol level (CMO:0000053) 3 20714090 65714090 Rat 8694386 Bw159 Body weight QTL 159 4.52 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 3 28249687 73249687 Rat 1354604 Bw36 Body weight QTL 36 2.9 body mass (VT:0001259) body weight (CMO:0000012) 3 33703347 104104347 Rat 631665 Bw8 Body weight QTL 8 5.5 body mass (VT:0001259) body weight (CMO:0000012) 3 50437042 119183768 Rat 2301400 Cm68 Cardiac mass QTL 68 0.001 heart mass (VT:0007028) heart wet weight to body weight ratio (CMO:0002408) 3 31426403 70668733 Rat 1358186 Ept2 Estrogen-induced pituitary tumorigenesis QTL 2 8.3 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 3 47233430 110362260 Rat
RH98821
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 61,675,712 - 61,675,852 (+) MAPPER mRatBN7.2 Rnor_6.0 3 63,588,441 - 63,588,580 NCBI Rnor6.0 Rnor_5.0 3 70,162,177 - 70,162,316 UniSTS Rnor5.0 RGSC_v3.4 3 59,427,737 - 59,427,876 UniSTS RGSC3.4 Celera 3 61,161,160 - 61,161,299 UniSTS Cytogenetic Map 3 q23 UniSTS
RH131516
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 61,862,090 - 61,862,296 (+) MAPPER mRatBN7.2 Rnor_6.0 3 63,775,710 - 63,775,915 NCBI Rnor6.0 Rnor_5.0 3 70,346,833 - 70,347,038 UniSTS Rnor5.0 RGSC_v3.4 3 59,604,915 - 59,605,120 UniSTS RGSC3.4 Celera 3 61,346,433 - 61,346,638 UniSTS Cytogenetic Map 3 q23 UniSTS
RH137063
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 61,652,435 - 61,652,611 (+) MAPPER mRatBN7.2 Rnor_6.0 3 63,565,164 - 63,565,339 NCBI Rnor6.0 Rnor_5.0 3 70,138,900 - 70,139,075 UniSTS Rnor5.0 RGSC_v3.4 3 59,404,460 - 59,404,635 UniSTS RGSC3.4 Celera 3 61,137,885 - 61,138,060 UniSTS Cytogenetic Map 3 q23 UniSTS
MARC_23497-23498:1027358865:1
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 61,704,263 - 61,704,930 (+) MAPPER mRatBN7.2 Rnor_6.0 3 63,617,472 - 63,618,138 NCBI Rnor6.0 Rnor_5.0 3 70,189,953 - 70,190,619 UniSTS Rnor5.0 Celera 3 61,189,633 - 61,190,299 UniSTS Cytogenetic Map 3 q23 UniSTS
D2S1570E
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 61,724,050 - 61,724,240 (+) MAPPER mRatBN7.2 Rnor_6.0 3 63,636,859 - 63,637,048 NCBI Rnor6.0 Rnor_5.0 3 70,209,340 - 70,209,529 UniSTS Rnor5.0 RGSC_v3.4 3 59,465,671 - 59,465,860 UniSTS RGSC3.4 Celera 3 61,209,377 - 61,209,566 UniSTS Cytogenetic Map 3 q23 UniSTS
This gene Ttn is modified in the following models/strains:
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
Ensembl Acc Id:
ENSRNOT00000030978 ⟹ ENSRNOP00000033967
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 61,907,065 - 61,924,741 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000101577 ⟹ ENSRNOP00000081880
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 61,652,439 - 61,924,741 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000107188 ⟹ ENSRNOP00000084099
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 61,899,657 - 61,924,741 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000108121 ⟹ ENSRNOP00000086880
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 61,862,276 - 61,924,741 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000114553 ⟹ ENSRNOP00000082190
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 61,652,439 - 61,924,741 (-) Ensembl
RefSeq Acc Id:
NM_032068 ⟹ NP_114457
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,110 (-) NCBI
RefSeq Acc Id:
XM_039106384 ⟹ XP_038962312
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106385 ⟹ XP_038962313
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106386 ⟹ XP_038962314
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106387 ⟹ XP_038962315
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106388 ⟹ XP_038962316
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106389 ⟹ XP_038962317
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106391 ⟹ XP_038962319
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106393 ⟹ XP_038962321
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106400 ⟹ XP_038962328
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106402 ⟹ XP_038962330
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106403 ⟹ XP_038962331
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106405 ⟹ XP_038962333
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106406 ⟹ XP_038962334
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106407 ⟹ XP_038962335
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106408 ⟹ XP_038962336
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106409 ⟹ XP_038962337
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106412 ⟹ XP_038962340
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106413 ⟹ XP_038962341
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106415 ⟹ XP_038962343
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106416 ⟹ XP_038962344
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106417 ⟹ XP_038962345
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106418 ⟹ XP_038962346
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106420 ⟹ XP_038962348
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106421 ⟹ XP_038962349
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106423 ⟹ XP_038962351
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106424 ⟹ XP_038962352
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106425 ⟹ XP_038962353
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106426 ⟹ XP_038962354
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106428 ⟹ XP_038962356
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106429 ⟹ XP_038962357
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106430 ⟹ XP_038962358
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106431 ⟹ XP_038962359
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106432 ⟹ XP_038962360
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_039106433 ⟹ XP_038962361
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI mRatBN7.2 3 61,652,432 - 61,924,912 (-) NCBI
RefSeq Acc Id:
XM_063284689 ⟹ XP_063140759
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284690 ⟹ XP_063140760
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284691 ⟹ XP_063140761
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284693 ⟹ XP_063140763
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284694 ⟹ XP_063140764
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284695 ⟹ XP_063140765
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284696 ⟹ XP_063140766
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284697 ⟹ XP_063140767
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284699 ⟹ XP_063140769
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284700 ⟹ XP_063140770
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284701 ⟹ XP_063140771
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284702 ⟹ XP_063140772
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284703 ⟹ XP_063140773
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284705 ⟹ XP_063140775
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XM_063284706 ⟹ XP_063140776
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 82,059,648 - 82,332,130 (-) NCBI
RefSeq Acc Id:
XP_038962321 ⟸ XM_039106393
- Peptide Label:
isoform X12
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962319 ⟸ XM_039106391
- Peptide Label:
isoform X10
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962361 ⟸ XM_039106433
- Peptide Label:
isoform X49
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962360 ⟸ XM_039106432
- Peptide Label:
isoform X48
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962359 ⟸ XM_039106431
- Peptide Label:
isoform X47
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962358 ⟸ XM_039106430
- Peptide Label:
isoform X46
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962357 ⟸ XM_039106429
- Peptide Label:
isoform X45
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962356 ⟸ XM_039106428
- Peptide Label:
isoform X44
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962317 ⟸ XM_039106389
- Peptide Label:
isoform X8
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962315 ⟸ XM_039106387
- Peptide Label:
isoform X4
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962354 ⟸ XM_039106426
- Peptide Label:
isoform X42
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962349 ⟸ XM_039106421
- Peptide Label:
isoform X35
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962345 ⟸ XM_039106417
- Peptide Label:
isoform X29
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962340 ⟸ XM_039106412
- Peptide Label:
isoform X24
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962335 ⟸ XM_039106407
- Peptide Label:
isoform X21
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962353 ⟸ XM_039106425
- Peptide Label:
isoform X41
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962348 ⟸ XM_039106420
- Peptide Label:
isoform X33
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962343 ⟸ XM_039106415
- Peptide Label:
isoform X26
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962336 ⟸ XM_039106408
- Peptide Label:
isoform X22
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962334 ⟸ XM_039106406
- Peptide Label:
isoform X20
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962352 ⟸ XM_039106424
- Peptide Label:
isoform X38
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962346 ⟸ XM_039106418
- Peptide Label:
isoform X31
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962341 ⟸ XM_039106413
- Peptide Label:
isoform X25
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962333 ⟸ XM_039106405
- Peptide Label:
isoform X19
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962330 ⟸ XM_039106402
- Peptide Label:
isoform X17
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962351 ⟸ XM_039106423
- Peptide Label:
isoform X37
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962344 ⟸ XM_039106416
- Peptide Label:
isoform X28
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962337 ⟸ XM_039106409
- Peptide Label:
isoform X23
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962331 ⟸ XM_039106403
- Peptide Label:
isoform X18
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962328 ⟸ XM_039106400
- Peptide Label:
isoform X16
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962314 ⟸ XM_039106386
- Peptide Label:
isoform X3
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962316 ⟸ XM_039106388
- Peptide Label:
isoform X7
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962312 ⟸ XM_039106384
- Peptide Label:
isoform X1
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038962313 ⟸ XM_039106385
- Peptide Label:
isoform X2
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSRNOP00000084099 ⟸ ENSRNOT00000107188
Ensembl Acc Id:
ENSRNOP00000082190 ⟸ ENSRNOT00000114553
Ensembl Acc Id:
ENSRNOP00000086880 ⟸ ENSRNOT00000108121
Ensembl Acc Id:
ENSRNOP00000033967 ⟸ ENSRNOT00000030978
Ensembl Acc Id:
ENSRNOP00000081880 ⟸ ENSRNOT00000101577
RefSeq Acc Id:
XP_063140776 ⟸ XM_063284706
- Peptide Label:
isoform X43
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140759 ⟸ XM_063284689
- Peptide Label:
isoform X5
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140775 ⟸ XM_063284705
- Peptide Label:
isoform X40
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140773 ⟸ XM_063284703
- Peptide Label:
isoform X39
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140771 ⟸ XM_063284701
- Peptide Label:
isoform X34
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140772 ⟸ XM_063284702
- Peptide Label:
isoform X36
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140769 ⟸ XM_063284699
- Peptide Label:
isoform X30
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140770 ⟸ XM_063284700
- Peptide Label:
isoform X32
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140767 ⟸ XM_063284697
- Peptide Label:
isoform X27
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140766 ⟸ XM_063284696
- Peptide Label:
isoform X15
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140765 ⟸ XM_063284695
- Peptide Label:
isoform X14
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140763 ⟸ XM_063284693
- Peptide Label:
isoform X11
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140761 ⟸ XM_063284691
- Peptide Label:
isoform X9
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140760 ⟸ XM_063284690
- Peptide Label:
isoform X6
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063140764 ⟸ XM_063284694
- Peptide Label:
isoform X13
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
NP_114457 ⟸ NM_032068
- UniProtKB:
A0A8I5ZUN3 (UniProtKB/TrEMBL)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2022-06-02
Ttn
titin
Ttn
titin
Data merged from RGD:149736286
737654 PROVISIONAL
2021-08-09
Ttn
titin
Symbol and Name status set to provisional
45752 PROVISIONAL
2004-09-10
Ttn
titin
Symbol and Name status set to approved
1299863 APPROVED
2002-08-07
Ttn
titin
Symbol and Name status set to provisional
70820 PROVISIONAL
Note Type
Note
Reference
gene_function
acts as a template for myosin incorporation into thick filaments
634444
