Symbol:
Aif1
Name:
allograft inflammatory factor 1
RGD ID:
61924
Description:
Predicted to enable actin filament binding activity and calcium ion binding activity. Involved in several processes, including cellular response to morphine; positive regulation of metabolic process; and positive regulation of muscle hyperplasia. Located in cytoplasm; lamellipodium; and perikaryon. Used to study type 1 diabetes mellitus. Biomarker of brain disease (multiple); glomerulonephritis; interstitial cystitis; meningoencephalitis; and motor neuron disease. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human AIF1 (allograft inflammatory factor 1); INTERACTS WITH (+)-pilocarpine; (S)-colchicine; 1-naphthyl isothiocyanate.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
AIF-1; balloon angioplasty responsive transcript; balloon angioplasty-responsive transcript 1; BART-1; Bart1; iba1; ionized calcium binding adapter molecule 1; ionized calcium-binding adapter molecule 1; microglia response factor; mrf-1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Allele / Splice:
Aif1tm(EGFP)Apps
Genetic Models:
SD-Aif1tm(EGFP)Apps /Mmmc
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 20 3,651,435 - 3,657,341 (+) NCBI GRCr8 mRatBN7.2 20 3,646,784 - 3,652,670 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 20 3,646,777 - 3,652,668 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 20 4,350,088 - 4,351,997 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 20 3,712,144 - 3,714,054 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 20 4,249,928 - 4,251,828 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 20 5,161,350 - 5,167,176 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 5,161,333 - 5,166,448 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 20 7,234,609 - 7,240,454 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 20 3,714,428 - 3,716,327 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 20 3,714,654 - 3,716,552 NCBI Celera 20 4,373,127 - 4,375,026 (-) NCBI Celera Cytogenetic Map 20 p12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Aif1 Rat (+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of AIF1 protein CTD PMID:18226170 Aif1 Rat (1->4)-beta-D-glucan multiple interactions ISO Aif1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of AIF1 mRNA CTD PMID:36331819 Aif1 Rat (S)-colchicine decreases expression EXP 6480464 Colchicine results in decreased expression of AIF1 mRNA CTD PMID:20624997 Aif1 Rat 1,1-dichloroethene increases expression ISO Aif1 (Mus musculus) 6480464 vinylidene chloride results in increased expression of AIF1 mRNA CTD PMID:26682919 Aif1 Rat 1,2-dimethylhydrazine increases expression ISO Aif1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of AIF1 mRNA CTD PMID:22206623 Aif1 Rat 1,2-dimethylhydrazine multiple interactions ISO Aif1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AIF1 mRNA CTD PMID:22206623 Aif1 Rat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Aif1 (Mus musculus) 6480464 amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:28185818 more ... Aif1 Rat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression ISO Aif1 (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:28185818 more ... Aif1 Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of AIF1 mRNA CTD PMID:25380136 Aif1 Rat 17alpha-ethynylestradiol increases expression ISO Aif1 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of AIF1 mRNA CTD PMID:17942748 Aif1 Rat 17alpha-ethynylestradiol multiple interactions ISO Aif1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AIF1 mRNA CTD PMID:17942748 Aif1 Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of AIF1 mRNA CTD PMID:17351261 Aif1 Rat 17alpha-ethynylestradiol affects expression ISO Aif1 (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of AIF1 mRNA CTD PMID:17555576 Aif1 Rat 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of AIF1 mRNA and [Estradiol co-treated with Progesterone] results in decreased expression of AIF1 protein CTD PMID:21277368 and PMID:32741896 Aif1 Rat 17beta-estradiol decreases expression ISO Aif1 (Mus musculus) 6480464 Estradiol results in decreased expression of AIF1 mRNA CTD PMID:39298647 Aif1 Rat 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of AIF1 mRNA CTD PMID:32741896 Aif1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO AIF1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AIF1 mRNA CTD PMID:19684285 Aif1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of AIF1 mRNA CTD PMID:34747641 Aif1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Aif1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of AIF1 mRNA CTD PMID:24680724 and PMID:26377647 Aif1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Aif1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AIF1 mRNA CTD PMID:17942748 Aif1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO AIF1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of AIF1 mRNA CTD PMID:19684285 Aif1 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Aif1 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Aif1 Rat 2,5-hexanedione increases expression EXP 6480464 2 and 5-hexanedione results in increased expression of AIF1 protein CTD PMID:32522579 and PMID:32860822 Aif1 Rat 2,5-hexanedione multiple interactions EXP 6480464 Glyburide inhibits the reaction [2 and 5-hexanedione results in increased expression of AIF1 protein] CTD PMID:32522579 and PMID:32860822 Aif1 Rat 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of AIF1 mRNA CTD PMID:14600272 Aif1 Rat 2-palmitoylglycerol increases expression ISO AIF1 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of AIF1 mRNA CTD PMID:37199045 Aif1 Rat 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of AIF1 mRNA CTD PMID:28300664 Aif1 Rat 3,3'-diindolylmethane multiple interactions ISO Aif1 (Mus musculus) 6480464 3 and 3'-diindolylmethane inhibits the reaction [Lipopolysaccharides results in increased expression of AIF1 protein] CTD PMID:24162184 Aif1 Rat 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of AIF1 mRNA CTD PMID:19162173 Aif1 Rat 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of AIF1 mRNA CTD PMID:25380136 Aif1 Rat 4,4'-sulfonyldiphenol decreases expression ISO Aif1 (Mus musculus) 6480464 bisphenol S results in decreased expression of AIF1 mRNA CTD PMID:39298647 Aif1 Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of AIF1 mRNA CTD PMID:14600272 Aif1 Rat 6-Methoxyflavone multiple interactions ISO Aif1 (Mus musculus) 6480464 6-methoxyflavone inhibits the reaction [lipopolysaccharide and E coli O55-B5 results in increased expression of AIF1 protein] CTD PMID:35272244 Aif1 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of AIF1 mRNA CTD PMID:30047161 Aif1 Rat 8-OH-DPAT increases expression ISO Aif1 (Mus musculus) 6480464 8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein CTD PMID:30366073 Aif1 Rat 8-OH-DPAT multiple interactions ISO Aif1 (Mus musculus) 6480464 acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein] more ... CTD PMID:30366073 Aif1 Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of AIF1 mRNA CTD PMID:31881176 Aif1 Rat aconitine decreases expression EXP 6480464 Aconitine results in decreased expression of AIF1 protein CTD PMID:33236894 Aif1 Rat aflatoxin B1 decreases expression ISO AIF1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of AIF1 mRNA CTD PMID:22100608 Aif1 Rat agomelatine multiple interactions EXP 6480464 agomelatine inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:34673010 Aif1 Rat aldehydo-D-glucose multiple interactions ISO Aif1 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of AIF1 mRNA CTD PMID:37567420 Aif1 Rat all-trans-retinoic acid increases expression ISO AIF1 (Homo sapiens) 6480464 Tretinoin results in increased expression of AIF1 mRNA CTD PMID:15498508 and PMID:33167477 Aif1 Rat allyl isothiocyanate multiple interactions EXP 6480464 allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased expression of AIF1 protein] CTD PMID:27241356 Aif1 Rat alpha-D-galactose increases expression ISO Aif1 (Mus musculus) 6480464 Galactose results in increased expression of AIF1 protein CTD PMID:28974442 Aif1 Rat alpha-D-galactose increases expression EXP 6480464 Galactose results in increased expression of AIF1 protein CTD PMID:34673010 Aif1 Rat alpha-D-galactose multiple interactions EXP 6480464 agomelatine inhibits the reaction [Galactose results in increased expression of AIF1 protein] and Melatonin inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:34673010 Aif1 Rat alpha-D-galactose multiple interactions ISO Aif1 (Mus musculus) 6480464 lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:28974442 Aif1 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of AIF1 mRNA CTD PMID:35163327 Aif1 Rat amentoflavone multiple interactions ISO Aif1 (Mus musculus) 6480464 amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:28185818 Aif1 Rat aminoguanidine multiple interactions EXP 6480464 pimagedine inhibits the reaction [Methylmalonic Acid results in increased expression of AIF1 protein] CTD PMID:28223158 Aif1 Rat amitrole increases expression EXP 6480464 Amitrole results in increased expression of AIF1 mRNA CTD PMID:30047161 Aif1 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of AIF1 mRNA CTD PMID:16483693 Aif1 Rat amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of AIF1 mRNA CTD PMID:30779732 Aif1 Rat antirheumatic drug decreases expression ISO AIF1 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of AIF1 mRNA CTD PMID:24449571 Aif1 Rat apocynin multiple interactions ISO Aif1 (Mus musculus) 6480464 acetovanillone inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein] and acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of AIF1 protein] CTD PMID:28202386 and PMID:30366073 Aif1 Rat arsane multiple interactions ISO Aif1 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of AIF1 mRNA CTD PMID:35777461 Aif1 Rat arsenic atom multiple interactions ISO Aif1 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of AIF1 mRNA CTD PMID:35777461 Aif1 Rat arsenite(3-) decreases expression ISO Aif1 (Mus musculus) 6480464 arsenite results in decreased expression of AIF1 protein CTD PMID:37955338 Aif1 Rat arsenous acid decreases expression ISO AIF1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of AIF1 mRNA CTD PMID:19128835 Aif1 Rat azithromycin increases expression ISO Aif1 (Mus musculus) 6480464 Azithromycin results in increased expression of AIF1 mRNA CTD PMID:37995777 Aif1 Rat baicalin multiple interactions ISO Aif1 (Mus musculus) 6480464 baicalin inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:38016618 Aif1 Rat benzene affects expression EXP 6480464 Benzene affects the expression of AIF1 mRNA CTD PMID:15878777 Aif1 Rat benzene increases expression ISO Aif1 (Mus musculus) 6480464 Benzene results in increased expression of AIF1 protein CTD PMID:37084897 Aif1 Rat benzo[a]pyrene multiple interactions ISO Aif1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of AIF1 mRNA more ... CTD PMID:19654925 more ... Aif1 Rat benzo[a]pyrene increases expression ISO AIF1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of AIF1 protein CTD PMID:34332006 Aif1 Rat benzo[a]pyrene affects methylation ISO AIF1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of AIF1 promoter CTD PMID:27901495 Aif1 Rat benzo[a]pyrene increases expression ISO Aif1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of AIF1 mRNA CTD PMID:22228805 Aif1 Rat benzo[b]fluoranthene multiple interactions ISO Aif1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of AIF1 mRNA CTD PMID:27858113 Aif1 Rat Benzo[k]fluoranthene increases expression ISO Aif1 (Mus musculus) 6480464 benzo(k)fluoranthene results in increased expression of AIF1 mRNA CTD PMID:26377693 Aif1 Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Aif1 (Mus musculus) 6480464 [Diethylhexyl Phthalate co-treated with OVAL protein] results in increased expression of AIF1 mRNA CTD PMID:23148021 Aif1 Rat bisphenol A increases expression ISO Aif1 (Mus musculus) 6480464 bisphenol A results in increased expression of AIF1 mRNA and bisphenol A results in increased expression of AIF1 protein CTD PMID:24824810 and PMID:29248573 Aif1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of AIF1 mRNA CTD PMID:32145629 Aif1 Rat bisphenol A multiple interactions ISO Aif1 (Mus musculus) 6480464 [NR1H4 gene mutant form affects the susceptibility to bisphenol A] which results in decreased expression of AIF1 mRNA CTD PMID:30245210 Aif1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of AIF1 mRNA CTD PMID:25181051 and PMID:34947998 Aif1 Rat bisphenol F increases expression ISO Aif1 (Mus musculus) 6480464 bisphenol F results in increased expression of AIF1 protein CTD PMID:38266696 Aif1 Rat buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of AIF1 mRNA CTD PMID:24136188 Aif1 Rat cadmium atom multiple interactions ISO AIF1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of AIF1 mRNA CTD PMID:35301059 Aif1 Rat cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of AIF1 mRNA CTD PMID:39025289 Aif1 Rat cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of AIF1 promoter CTD PMID:22457795 Aif1 Rat cadmium dichloride multiple interactions ISO AIF1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of AIF1 mRNA CTD PMID:35301059 Aif1 Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of AIF1 mRNA CTD PMID:25993096 Aif1 Rat calcitriol decreases expression EXP 6480464 Calcitriol results in decreased expression of AIF1 protein CTD PMID:32147540 Aif1 Rat cannabidiol multiple interactions EXP 6480464 Cannabidiol inhibits the reaction [Ketamine results in decreased expression of AIF1 mRNA] CTD PMID:31823199 Aif1 Rat carbon nanotube increases expression ISO Aif1 (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of AIF1 mRNA CTD PMID:25554681 Aif1 Rat carbon nanotube decreases expression ISO Aif1 (Mus musculus) 6480464 Nanotubes and Carbon analog results in decreased expression of AIF1 mRNA CTD PMID:25620056 Aif1 Rat carbon nanotube affects expression ISO Aif1 (Mus musculus) 6480464 Nanotubes and Carbon affects the expression of AIF1 mRNA CTD PMID:25554681 Aif1 Rat chloroprene decreases expression ISO Aif1 (Mus musculus) 6480464 Chloroprene results in decreased expression of AIF1 mRNA CTD PMID:23125180 Aif1 Rat chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of AIF1 protein CTD PMID:26524701 Aif1 Rat chlorpyrifos increases expression ISO Aif1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of AIF1 protein CTD PMID:33839396 Aif1 Rat chrysene multiple interactions ISO Aif1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of AIF1 mRNA CTD PMID:27858113 Aif1 Rat cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of AIF1 mRNA CTD PMID:22023808 Aif1 Rat copper atom multiple interactions ISO Aif1 (Mus musculus) 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of AIF1 protein CTD PMID:36775208 Aif1 Rat copper atom decreases expression EXP 6480464 Copper results in decreased expression of AIF1 mRNA CTD PMID:30556269 Aif1 Rat copper(0) decreases expression EXP 6480464 Copper results in decreased expression of AIF1 mRNA CTD PMID:30556269 Aif1 Rat copper(0) multiple interactions ISO Aif1 (Mus musculus) 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of AIF1 protein CTD PMID:36775208 Aif1 Rat copper(II) sulfate decreases expression ISO AIF1 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of AIF1 mRNA CTD PMID:19549813 Aif1 Rat copper(II) sulfate multiple interactions ISO Aif1 (Mus musculus) 6480464 [Copper Sulfate results in increased abundance of Copper] which results in increased expression of AIF1 protein CTD PMID:36775208 Aif1 Rat corilagin multiple interactions ISO Aif1 (Mus musculus) 6480464 corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein] more ... CTD PMID:37394652 Aif1 Rat Cuprizon increases expression ISO Aif1 (Mus musculus) 6480464 Cuprizone results in increased expression of AIF1 protein CTD PMID:30468814 Aif1 Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of AIF1 mRNA and Cuprizone results in increased expression of AIF1 protein CTD PMID:27523638 Aif1 Rat cyhalothrin increases expression EXP 6480464 cyhalothrin results in increased expression of AIF1 protein CTD PMID:37060950 Aif1 Rat cyprodinil multiple interactions ISO AIF1 (Homo sapiens) 6480464 [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of AIF1 protein] CTD PMID:31939705 Aif1 Rat cyprodinil multiple interactions ISO Aif1 (Mus musculus) 6480464 [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] results in increased expression of AIF1 protein CTD PMID:31939705 Aif1 Rat D-glucose multiple interactions ISO Aif1 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of AIF1 mRNA CTD PMID:37567420 Aif1 Rat dabigatran decreases expression ISO Aif1 (Mus musculus) 6480464 Dabigatran results in decreased expression of AIF1 protein CTD PMID:27397090 Aif1 Rat decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of AIF1 mRNA and decabromobiphenyl ether results in increased expression of IBA1 protein CTD PMID:23640034 and PMID:36566971 Aif1 Rat decabromodiphenyl ether multiple interactions EXP 6480464 Melatonin inhibits the reaction [decabromobiphenyl ether results in increased expression of IBA1 protein] CTD PMID:36566971 Aif1 Rat diarsenic trioxide decreases expression ISO AIF1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of AIF1 mRNA CTD PMID:19128835 Aif1 Rat Dibutyl phosphate affects expression ISO AIF1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of AIF1 mRNA CTD PMID:37042841 Aif1 Rat diisopropyl fluorophosphate increases expression EXP 6480464 Isoflurophate results in increased expression of AIF1 protein CTD PMID:28329845 Aif1 Rat diuron decreases expression EXP 6480464 Diuron results in decreased expression of AIF1 mRNA CTD PMID:25152437 Aif1 Rat diuron decreases expression ISO AIF1 (Homo sapiens) 6480464 Diuron results in decreased expression of AIF1 mRNA CTD PMID:35967413 Aif1 Rat doxorubicin decreases expression ISO Aif1 (Mus musculus) 6480464 Doxorubicin results in decreased expression of AIF1 mRNA CTD PMID:25896364 Aif1 Rat entinostat increases expression ISO AIF1 (Homo sapiens) 6480464 entinostat results in increased expression of AIF1 mRNA CTD PMID:27188386 Aif1 Rat ethanol increases expression EXP 6480464 Ethanol results in increased expression of AIF1 mRNA CTD PMID:30098312 Aif1 Rat ethanol multiple interactions ISO Aif1 (Mus musculus) 6480464 Ethanol promotes the reaction [Dietary Fats results in increased expression of AIF1 mRNA] CTD PMID:35863473 Aif1 Rat ethanol affects expression EXP 6480464 Ethanol affects the expression of AIF1 mRNA CTD PMID:34547370 Aif1 Rat ethanol multiple interactions EXP 6480464 cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Ethanol results in increased expression of AIF1 mRNA] CTD PMID:30098312 Aif1 Rat ethylmalonic acid increases expression EXP 6480464 Methylmalonic Acid results in increased expression of AIF1 protein CTD PMID:28223158 Aif1 Rat ethylmalonic acid multiple interactions EXP 6480464 pimagedine inhibits the reaction [Methylmalonic Acid results in increased expression of AIF1 protein] CTD PMID:28223158 Aif1 Rat ethylparaben decreases expression ISO AIF1 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate results in decreased expression of AIF1 mRNA CTD PMID:37690743 Aif1 Rat flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of AIF1 mRNA CTD PMID:18035473 Aif1 Rat flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of AIF1 mRNA CTD PMID:24136188 Aif1 Rat folic acid multiple interactions ISO Aif1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of AIF1 mRNA CTD PMID:22206623 Aif1 Rat fructose multiple interactions ISO Aif1 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of AIF1 mRNA CTD PMID:37567420 Aif1 Rat galactose increases expression ISO Aif1 (Mus musculus) 6480464 Galactose results in increased expression of AIF1 protein CTD PMID:28974442 Aif1 Rat galactose multiple interactions EXP 6480464 agomelatine inhibits the reaction [Galactose results in increased expression of AIF1 protein] and Melatonin inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:34673010 Aif1 Rat galactose increases expression EXP 6480464 Galactose results in increased expression of AIF1 protein CTD PMID:34673010 Aif1 Rat galactose multiple interactions ISO Aif1 (Mus musculus) 6480464 lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:28974442 Aif1 Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of AIF1 mRNA CTD PMID:22061828 Aif1 Rat ginkgolide B multiple interactions ISO Aif1 (Mus musculus) 6480464 ginkgolide B affects the reaction [GPX1 protein affects the expression of AIF1 protein] CTD PMID:36682417 Aif1 Rat ginkgolide B decreases expression ISO Aif1 (Mus musculus) 6480464 ginkgolide B results in decreased expression of AIF1 protein CTD PMID:36682417 Aif1 Rat ginsenoside Re multiple interactions ISO Aif1 (Mus musculus) 6480464 3-((3 more ... CTD PMID:29467000 and PMID:36682417 Aif1 Rat ginsenoside Re decreases expression ISO Aif1 (Mus musculus) 6480464 ginsenoside Re results in decreased expression of AIF1 protein CTD PMID:36682417 Aif1 Rat glucose multiple interactions ISO Aif1 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of AIF1 mRNA CTD PMID:37567420 Aif1 Rat glyburide multiple interactions EXP 6480464 Glyburide inhibits the reaction [2 and 5-hexanedione results in increased expression of AIF1 protein] CTD PMID:32522579 and PMID:32860822 Aif1 Rat glyburide multiple interactions ISO Aif1 (Mus musculus) 6480464 Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of AIF1 protein] CTD PMID:32375810 Aif1 Rat glyphosate multiple interactions ISO Aif1 (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of AIF1 mRNA CTD PMID:37567420 Aif1 Rat hexachlorobenzene affects expression EXP 6480464 Hexachlorobenzene affects the expression of AIF1 mRNA CTD PMID:15159207 Aif1 Rat Ibudilast multiple interactions EXP 6480464 ibudilast inhibits the reaction [Dronabinol results in increased expression of AIF1 protein] CTD PMID:26499171 Aif1 Rat imidacloprid increases expression EXP 6480464 imidacloprid results in increased expression of AIF1 mRNA CTD PMID:39002876 Aif1 Rat isoprenaline decreases expression ISO Aif1 (Mus musculus) 6480464 Isoproterenol results in decreased expression of AIF1 mRNA CTD PMID:20003209 Aif1 Rat Jujuboside A multiple interactions ISO Aif1 (Mus musculus) 6480464 jujuboside A affects the reaction [[Midazolam co-treated with Lipopolysaccharides] affects the expression of AIF1 protein] and NFIL3 protein affects the reaction [jujuboside A affects the reaction [[Midazolam co-treated with Lipopolysaccharides] affects the expression of AIF1 protein]] CTD PMID:37330271 Aif1 Rat kainic acid increases expression EXP 6480464 Kainic Acid results in increased expression of AIF1 protein CTD PMID:32057834 Aif1 Rat kainic acid multiple interactions ISO Aif1 (Mus musculus) 6480464 [cyanoginosin LR co-treated with Kainic Acid] results in increased expression of AIF1 protein CTD PMID:34352349 Aif1 Rat kainic acid multiple interactions EXP 6480464 NADP inhibits the reaction [Kainic Acid results in increased expression of AIF1 protein] CTD PMID:32057834 Aif1 Rat ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of AIF1 mRNA CTD PMID:31823199 Aif1 Rat ketamine decreases expression ISO Aif1 (Mus musculus) 6480464 Ketamine results in decreased expression of AIF1 protein CTD PMID:36172893 Aif1 Rat ketamine multiple interactions EXP 6480464 Cannabidiol inhibits the reaction [Ketamine results in decreased expression of AIF1 mRNA] CTD PMID:31823199 Aif1 Rat L-gamma-glutamyl-L-cysteine multiple interactions ISO Aif1 (Mus musculus) 6480464 gamma-glutamylcysteine inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of AIF1 protein] CTD PMID:35714925 Aif1 Rat lead diacetate increases expression ISO Aif1 (Mus musculus) 6480464 lead acetate results in increased expression of AIF1 mRNA and lead acetate results in increased expression of AIF1 protein CTD PMID:21829687 and PMID:38281554 Aif1 Rat lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of AIF1 mRNA CTD PMID:33862172 Aif1 Rat lead diacetate multiple interactions EXP 6480464 [lead acetate co-treated with Morphine] results in increased expression of AIF1 mRNA CTD PMID:26478469 Aif1 Rat lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of AIF1 mRNA and lead acetate results in increased expression of AIF1 protein CTD PMID:26478469 more ... Aif1 Rat lipopolysaccharide multiple interactions ISO Aif1 (Mus musculus) 6480464 3 more ... CTD PMID:24162184 more ... Aif1 Rat lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of AIF1 CTD PMID:25447322 Aif1 Rat lipopolysaccharide increases expression ISO Aif1 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of AIF1 more ... CTD PMID:21245015 more ... Aif1 Rat lycopene multiple interactions ISO Aif1 (Mus musculus) 6480464 lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:28974442 Aif1 Rat Magnolol multiple interactions ISO Aif1 (Mus musculus) 6480464 magnolol inhibits the reaction [trimethyltin results in increased expression of AIF1 protein] CTD PMID:26756313 Aif1 Rat maneb multiple interactions ISO Aif1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in increased expression of AIF1 protein more ... CTD PMID:28202386 and PMID:32375810 Aif1 Rat manganese(II) chloride increases expression ISO Aif1 (Mus musculus) 6480464 manganese chloride results in increased expression of AIF1 protein CTD PMID:28595911 Aif1 Rat medroxyprogesterone acetate increases expression ISO AIF1 (Homo sapiens) 6480464 Medroxyprogesterone Acetate results in increased expression of AIF1 mRNA CTD PMID:20843944 Aif1 Rat melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [decabromobiphenyl ether results in increased expression of IBA1 protein] and Melatonin inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:34673010 and PMID:36566971 Aif1 Rat mepanipyrim multiple interactions ISO AIF1 (Homo sapiens) 6480464 [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of AIF1 protein] CTD PMID:31939705 Aif1 Rat mepanipyrim multiple interactions ISO Aif1 (Mus musculus) 6480464 [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] results in increased expression of AIF1 protein CTD PMID:31939705 Aif1 Rat methamphetamine increases expression ISO Aif1 (Mus musculus) 6480464 Methamphetamine results in increased expression of AIF1 protein CTD PMID:26283213 more ... Aif1 Rat methamphetamine multiple interactions ISO Aif1 (Mus musculus) 6480464 3-((3 more ... CTD PMID:29467000 more ... Aif1 Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of AIF1 mRNA CTD PMID:30047161 Aif1 Rat methylmalonic acid multiple interactions EXP 6480464 pimagedine inhibits the reaction [Methylmalonic Acid results in increased expression of AIF1 protein] CTD PMID:28223158 Aif1 Rat methylmalonic acid increases expression EXP 6480464 Methylmalonic Acid results in increased expression of AIF1 protein CTD PMID:28223158 Aif1 Rat methylmercury chloride decreases expression ISO Aif1 (Mus musculus) 6480464 methylmercuric chloride results in decreased expression of AIF1 protein CTD PMID:33338554 Aif1 Rat microcystin-LR multiple interactions ISO Aif1 (Mus musculus) 6480464 [cyanoginosin LR co-treated with Kainic Acid] results in increased expression of AIF1 protein CTD PMID:34352349 Aif1 Rat midazolam multiple interactions ISO Aif1 (Mus musculus) 6480464 [Midazolam co-treated with Lipopolysaccharides] affects the expression of AIF1 protein more ... CTD PMID:37330271 Aif1 Rat minocycline multiple interactions ISO Aif1 (Mus musculus) 6480464 Minocycline affects the reaction [GPX1 protein affects the expression of AIF1 protein] more ... CTD PMID:32916201 more ... Aif1 Rat minocycline decreases expression ISO Aif1 (Mus musculus) 6480464 Minocycline results in decreased expression of AIF1 protein CTD PMID:36682417 Aif1 Rat morphine multiple interactions EXP 6480464 [lead acetate co-treated with Morphine] results in increased expression of AIF1 mRNA CTD PMID:26478469 Aif1 Rat morphine multiple interactions ISO Aif1 (Mus musculus) 6480464 corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein] more ... CTD PMID:37394652 Aif1 Rat morphine increases expression ISO Aif1 (Mus musculus) 6480464 Morphine results in increased expression of AIF1 protein CTD PMID:37394652 Aif1 Rat Muraglitazar decreases expression EXP 6480464 muraglitazar results in decreased expression of AIF1 mRNA CTD PMID:21515302 Aif1 Rat mycophenolic acid decreases expression EXP 6480464 Mycophenolic Acid results in decreased expression of AIF1 mRNA CTD PMID:10688038 Aif1 Rat mycophenolic acid multiple interactions EXP 6480464 [Quercetin co-treated with Mycophenolic Acid] results in decreased expression of AIF1 mRNA CTD PMID:10688038 Aif1 Rat N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide multiple interactions ISO Aif1 (Mus musculus) 6480464 N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein] CTD PMID:30366073 Aif1 Rat N-acetyl-L-cysteine multiple interactions ISO Aif1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of AIF1 protein]] CTD PMID:36762617 Aif1 Rat N-butylbenzenesulfonamide decreases expression EXP 6480464 N-butylbenzenesulfonamide results in decreased expression of AIF1 mRNA CTD PMID:22824510 Aif1 Rat N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of AIF1 mRNA CTD PMID:28801915 Aif1 Rat N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of AIF1 mRNA CTD PMID:14600272 and PMID:25380136 Aif1 Rat NADP zwitterion multiple interactions EXP 6480464 NADP inhibits the reaction [Kainic Acid results in increased expression of AIF1 protein] CTD PMID:32057834 Aif1 Rat NADP(+) multiple interactions EXP 6480464 NADP inhibits the reaction [Kainic Acid results in increased expression of AIF1 protein] CTD PMID:32057834 Aif1 Rat nevirapine decreases expression EXP 6480464 Nevirapine metabolite results in decreased expression of AIF1 mRNA CTD PMID:23947594 Aif1 Rat nickel atom increases expression ISO AIF1 (Homo sapiens) 6480464 Nickel results in increased expression of AIF1 mRNA CTD PMID:25583101 Aif1 Rat nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of AIF1 mRNA CTD PMID:24136188 Aif1 Rat nitrofen increases expression EXP 6480464 nitrofen results in increased expression of AIF1 mRNA CTD PMID:33484710 Aif1 Rat Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of AIF1 protein CTD PMID:30481583 Aif1 Rat Norbinaltorphimine multiple interactions ISO Aif1 (Mus musculus) 6480464 3-((3 more ... CTD PMID:29467000 Aif1 Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of AIF1 mRNA CTD PMID:25729387 Aif1 Rat oxybenzone increases expression EXP 6480464 oxybenzone results in increased expression of AIF1 mRNA and oxybenzone results in increased expression of AIF1 protein CTD PMID:31368502 Aif1 Rat p-menthan-3-ol increases expression ISO AIF1 (Homo sapiens) 6480464 Menthol results in increased expression of AIF1 mRNA CTD PMID:26760959 Aif1 Rat paraquat multiple interactions ISO Aif1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in increased expression of AIF1 protein more ... CTD PMID:28202386 more ... Aif1 Rat paraquat multiple interactions EXP 6480464 Paraquat promotes the reaction [Zinc results in increased expression of AIF1 protein] and Zinc promotes the reaction [Paraquat results in increased expression of AIF1 protein] CTD PMID:32060784 Aif1 Rat paraquat increases expression EXP 6480464 Paraquat results in increased expression of AIF1 protein CTD PMID:32060784 Aif1 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Aif1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of AIF1 mRNA CTD PMID:36331819 Aif1 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of AIF1 mRNA CTD PMID:35163327 Aif1 Rat permethrin multiple interactions ISO Aif1 (Mus musculus) 6480464 [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of AIF1 protein CTD PMID:27984134 Aif1 Rat pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of AIF1 mRNA CTD PMID:19162173 Aif1 Rat pravastatin decreases expression EXP 6480464 Pravastatin results in decreased expression of AIF1 mRNA CTD PMID:27225895 Aif1 Rat pravastatin decreases expression ISO Aif1 (Mus musculus) 6480464 Pravastatin results in decreased expression of AIF1 mRNA CTD PMID:27225895 Aif1 Rat pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of AIF1 mRNA CTD PMID:19162173 Aif1 Rat progesterone multiple interactions EXP 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of AIF1 protein CTD PMID:21277368 Aif1 Rat Pyridostigmine bromide multiple interactions ISO Aif1 (Mus musculus) 6480464 [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of AIF1 protein CTD PMID:27984134 Aif1 Rat pyrimethanil multiple interactions ISO Aif1 (Mus musculus) 6480464 [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] results in increased expression of AIF1 protein CTD PMID:31939705 Aif1 Rat pyrimethanil multiple interactions ISO AIF1 (Homo sapiens) 6480464 [cyprodinil co-treated with mepanipyrim co-treated with pyrimethanil] promotes the reaction [[APP gene mutant form results in increased expression of APP protein modified form] which results in increased expression of AIF1 protein] CTD PMID:31939705 Aif1 Rat pyrrolidine dithiocarbamate decreases expression ISO Aif1 (Mus musculus) 6480464 pyrrolidine dithiocarbamic acid results in decreased expression of AIF1 protein CTD PMID:36682417 Aif1 Rat pyrrolidine dithiocarbamate multiple interactions ISO Aif1 (Mus musculus) 6480464 pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the expression of AIF1 protein] CTD PMID:36682417 Aif1 Rat quercetin multiple interactions EXP 6480464 [Quercetin co-treated with Mycophenolic Acid] results in decreased expression of AIF1 mRNA CTD PMID:10688038 Aif1 Rat quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of AIF1 mRNA CTD PMID:10688038 Aif1 Rat quinoline increases activity ISO AIF1 (Homo sapiens) 6480464 quinoline analog results in increased activity of AIF1 protein CTD PMID:18645022 Aif1 Rat resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of AIF1 protein CTD PMID:27093858 Aif1 Rat resveratrol multiple interactions ISO Aif1 (Mus musculus) 6480464 Resveratrol inhibits the reaction [Aluminum Chloride results in increased expression of AIF1 protein] and Resveratrol inhibits the reaction [Rotenone results in increased expression of AIF1 protein] CTD PMID:34391968 and PMID:34614429 Aif1 Rat rotenone increases expression EXP 6480464 Rotenone results in increased expression of AIF1 protein CTD PMID:23098804 and PMID:27316720 Aif1 Rat rotenone multiple interactions ISO Aif1 (Mus musculus) 6480464 Resveratrol inhibits the reaction [Rotenone results in increased expression of AIF1 protein] CTD PMID:34391968 Aif1 Rat rotenone increases expression ISO Aif1 (Mus musculus) 6480464 Rotenone results in increased expression of AIF1 protein CTD PMID:33402167 and PMID:34391968 Aif1 Rat rotenone multiple interactions EXP 6480464 caryophyllene inhibits the reaction [Rotenone results in increased expression of AIF1 protein] CTD PMID:27316720 Aif1 Rat rottlerin multiple interactions ISO Aif1 (Mus musculus) 6480464 rottlerin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased expression of AIF1 protein] CTD PMID:30366073 Aif1 Rat SCH 23390 multiple interactions ISO Aif1 (Mus musculus) 6480464 SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of AIF1 protein] CTD PMID:30922767 Aif1 Rat senecionine decreases expression ISO Aif1 (Mus musculus) 6480464 senecionine results in decreased expression of AIF1 protein CTD PMID:35357534 Aif1 Rat silicon dioxide increases expression ISO Aif1 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of AIF1 mRNA CTD PMID:29341224 Aif1 Rat sodium arsenite decreases expression ISO Aif1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of AIF1 mRNA and sodium arsenite results in decreased expression of AIF1 protein CTD PMID:29044176 and PMID:37682722 Aif1 Rat sodium arsenite multiple interactions ISO Aif1 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of AIF1 mRNA CTD PMID:35777461 Aif1 Rat sodium dichromate decreases expression ISO AIF1 (Homo sapiens) 6480464 sodium bichromate results in decreased expression of AIF1 mRNA CTD PMID:17685462 Aif1 Rat sodium dodecyl sulfate affects response to substance ISO AIF1 (Homo sapiens) 6480464 AIF1 SNP affects the susceptibility to Sodium Dodecyl Sulfate CTD PMID:27258892 Aif1 Rat sodium fluoride increases expression ISO Aif1 (Mus musculus) 6480464 Sodium Fluoride results in increased expression of AIF1 protein CTD PMID:24072958 Aif1 Rat Sophoricoside multiple interactions ISO Aif1 (Mus musculus) 6480464 sophoricoside inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:37741537 Aif1 Rat sulpiride multiple interactions ISO Aif1 (Mus musculus) 6480464 Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of AIF1 protein] CTD PMID:30922767 Aif1 Rat tacrolimus hydrate increases expression ISO Aif1 (Mus musculus) 6480464 Tacrolimus results in increased expression of AIF1 mRNA CTD PMID:29362864 Aif1 Rat tadalafil multiple interactions ISO Aif1 (Mus musculus) 6480464 Tadalafil inhibits the reaction [Thioacetamide results in increased expression of AIF1 protein] CTD PMID:31323263 Aif1 Rat tamibarotene increases expression ISO AIF1 (Homo sapiens) 6480464 tamibarotene results in increased expression of AIF1 mRNA CTD PMID:15498508 Aif1 Rat Tesaglitazar decreases expression EXP 6480464 tesaglitazar results in decreased expression of AIF1 mRNA CTD PMID:21515302 Aif1 Rat testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of AIF1 mRNA CTD PMID:32741896 Aif1 Rat testosterone increases expression ISO Aif1 (Mus musculus) 6480464 Testosterone deficiency results in increased expression of AIF1 mRNA CTD PMID:33848595 Aif1 Rat testosterone multiple interactions ISO Aif1 (Mus musculus) 6480464 1 more ... CTD PMID:33848595 Aif1 Rat tetrachloromethane increases expression ISO Aif1 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of AIF1 mRNA CTD PMID:27339419 Aif1 Rat tetrachloromethane affects expression ISO Aif1 (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of AIF1 mRNA CTD PMID:31919559 Aif1 Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of AIF1 protein CTD PMID:27241356 Aif1 Rat tetrachloromethane multiple interactions EXP 6480464 allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased expression of AIF1 protein] CTD PMID:27241356 Aif1 Rat tetraphene multiple interactions ISO Aif1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of AIF1 mRNA CTD PMID:27858113 Aif1 Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of AIF1 mRNA CTD PMID:23411599 Aif1 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of AIF1 mRNA CTD PMID:34492290 Aif1 Rat thioacetamide multiple interactions ISO Aif1 (Mus musculus) 6480464 Tadalafil inhibits the reaction [Thioacetamide results in increased expression of AIF1 protein] CTD PMID:31323263 Aif1 Rat thioacetamide increases expression ISO Aif1 (Mus musculus) 6480464 Thioacetamide results in increased expression of AIF1 protein CTD PMID:31323263 Aif1 Rat titanium dioxide increases expression ISO Aif1 (Mus musculus) 6480464 titanium dioxide results in increased expression of AIF1 mRNA CTD PMID:23557971 Aif1 Rat titanium dioxide decreases expression ISO Aif1 (Mus musculus) 6480464 titanium dioxide analog results in decreased expression of AIF1 mRNA CTD PMID:25111187 Aif1 Rat tolcapone decreases expression EXP 6480464 tolcapone results in decreased expression of AIF1 mRNA CTD PMID:24136188 Aif1 Rat toluene decreases expression EXP 6480464 Toluene results in decreased expression of AIF1 mRNA CTD PMID:22967744 Aif1 Rat toluene increases expression ISO Aif1 (Mus musculus) 6480464 Toluene results in increased expression of AIF1 mRNA CTD PMID:21381054 Aif1 Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of AIF1 mRNA CTD PMID:25729387 Aif1 Rat tributylstannane multiple interactions EXP 6480464 Phycocyanin inhibits the reaction [tributyltin results in decreased expression of AIF1 protein] CTD PMID:26079211 Aif1 Rat tributylstannane decreases expression EXP 6480464 tributyltin results in decreased expression of AIF1 protein CTD PMID:26079211 Aif1 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of AIF1 mRNA CTD PMID:33387578 Aif1 Rat trimethyltin increases expression ISO Aif1 (Mus musculus) 6480464 trimethyltin results in increased expression of AIF1 mRNA and trimethyltin results in increased expression of AIF1 protein CTD PMID:24002884 and PMID:26756313 Aif1 Rat trimethyltin multiple interactions ISO Aif1 (Mus musculus) 6480464 magnolol inhibits the reaction [trimethyltin results in increased expression of AIF1 protein] CTD PMID:26756313 Aif1 Rat triphenyl phosphate affects expression ISO AIF1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of AIF1 mRNA CTD PMID:37042841 Aif1 Rat tunicamycin multiple interactions ISO Aif1 (Mus musculus) 6480464 Tunicamycin inhibits the reaction [corilagin inhibits the reaction [Morphine results in increased expression of AIF1 protein]] CTD PMID:37394652 Aif1 Rat valproic acid increases expression ISO Aif1 (Mus musculus) 6480464 Valproic Acid results in increased expression of AIF1 protein CTD PMID:31369746 Aif1 Rat valproic acid affects expression ISO Aif1 (Mus musculus) 6480464 Valproic Acid affects the expression of AIF1 mRNA CTD PMID:17292431 Aif1 Rat vincaleukoblastine decreases expression EXP 6480464 Vinblastine results in decreased expression of AIF1 mRNA CTD PMID:20624997 Aif1 Rat vincamine multiple interactions ISO Aif1 (Mus musculus) 6480464 Vincamine inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:38629493 Aif1 Rat zaragozic acid A decreases expression EXP 6480464 squalestatin 1 results in decreased expression of AIF1 mRNA CTD PMID:27225895 Aif1 Rat zaragozic acid A decreases expression ISO Aif1 (Mus musculus) 6480464 squalestatin 1 results in decreased expression of AIF1 mRNA CTD PMID:27225895 Aif1 Rat zinc atom increases expression EXP 6480464 Zinc results in increased expression of AIF1 protein CTD PMID:32060784 Aif1 Rat zinc atom multiple interactions EXP 6480464 Paraquat promotes the reaction [Zinc results in increased expression of AIF1 protein] and Zinc promotes the reaction [Paraquat results in increased expression of AIF1 protein] CTD PMID:32060784 Aif1 Rat zinc(0) increases expression EXP 6480464 Zinc results in increased expression of AIF1 protein CTD PMID:32060784 Aif1 Rat zinc(0) multiple interactions EXP 6480464 Paraquat promotes the reaction [Zinc results in increased expression of AIF1 protein] and Zinc promotes the reaction [Paraquat results in increased expression of AIF1 protein] CTD PMID:32060784
(+)-pilocarpine (EXP) (1->4)-beta-D-glucan (ISO) (S)-colchicine (EXP) 1,1-dichloroethene (ISO) 1,2-dimethylhydrazine (ISO) 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO) 1-naphthyl isothiocyanate (EXP) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (EXP,ISO) 17beta-estradiol 3-benzoate (EXP) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2,5-hexanedione (EXP) 2-nitrofluorene (EXP) 2-palmitoylglycerol (ISO) 3,3',5,5'-tetrabromobisphenol A (EXP) 3,3'-diindolylmethane (ISO) 3H-1,2-dithiole-3-thione (EXP) 4,4'-diaminodiphenylmethane (EXP) 4,4'-sulfonyldiphenol (ISO) 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP) 6-Methoxyflavone (ISO) 6-propyl-2-thiouracil (EXP) 8-OH-DPAT (ISO) acetamide (EXP) aconitine (EXP) aflatoxin B1 (ISO) agomelatine (EXP) aldehydo-D-glucose (ISO) all-trans-retinoic acid (ISO) allyl isothiocyanate (EXP) alpha-D-galactose (EXP,ISO) alpha-Zearalanol (EXP) amentoflavone (ISO) aminoguanidine (EXP) amitrole (EXP) ammonium chloride (EXP) amphetamine (EXP) antirheumatic drug (ISO) apocynin (ISO) arsane (ISO) arsenic atom (ISO) arsenite(3-) (ISO) arsenous acid (ISO) azithromycin (ISO) baicalin (ISO) benzene (EXP,ISO) benzo[a]pyrene (ISO) benzo[b]fluoranthene (ISO) Benzo[k]fluoranthene (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bisphenol F (ISO) buspirone (EXP) cadmium atom (EXP,ISO) cadmium dichloride (EXP,ISO) calcitriol (EXP) cannabidiol (EXP) carbon nanotube (ISO) chloroprene (ISO) chlorpyrifos (EXP,ISO) chrysene (ISO) cisplatin (EXP) copper atom (EXP,ISO) copper(0) (EXP,ISO) copper(II) sulfate (ISO) corilagin (ISO) Cuprizon (EXP,ISO) cyhalothrin (EXP) cyprodinil (ISO) D-glucose (ISO) dabigatran (ISO) decabromodiphenyl ether (EXP) diarsenic trioxide (ISO) Dibutyl phosphate (ISO) diisopropyl fluorophosphate (EXP) diuron (EXP,ISO) doxorubicin (ISO) entinostat (ISO) ethanol (EXP,ISO) ethylmalonic acid (EXP) ethylparaben (ISO) flavonoids (EXP) flutamide (EXP) folic acid (ISO) fructose (ISO) galactose (EXP,ISO) gentamycin (EXP) ginkgolide B (ISO) ginsenoside Re (ISO) glucose (ISO) glyburide (EXP,ISO) glyphosate (ISO) hexachlorobenzene (EXP) Ibudilast (EXP) imidacloprid (EXP) isoprenaline (ISO) Jujuboside A (ISO) kainic acid (EXP,ISO) ketamine (EXP,ISO) L-gamma-glutamyl-L-cysteine (ISO) lead diacetate (EXP,ISO) lipopolysaccharide (EXP,ISO) lycopene (ISO) Magnolol (ISO) maneb (ISO) manganese(II) chloride (ISO) medroxyprogesterone acetate (ISO) melatonin (EXP) mepanipyrim (ISO) methamphetamine (ISO) methimazole (EXP) methylmalonic acid (EXP) methylmercury chloride (ISO) microcystin-LR (ISO) midazolam (ISO) minocycline (ISO) morphine (EXP,ISO) Muraglitazar (EXP) mycophenolic acid (EXP) N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide (ISO) N-acetyl-L-cysteine (ISO) N-butylbenzenesulfonamide (EXP) N-methyl-4-phenylpyridinium (EXP) N-nitrosodimethylamine (EXP) NADP zwitterion (EXP) NADP(+) (EXP) nevirapine (EXP) nickel atom (ISO) nimesulide (EXP) nitrofen (EXP) Nonylphenol (EXP) Norbinaltorphimine (ISO) oxaliplatin (EXP) oxybenzone (EXP) p-menthan-3-ol (ISO) paraquat (EXP,ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (EXP) permethrin (ISO) pirinixic acid (EXP) pravastatin (EXP,ISO) pregnenolone 16alpha-carbonitrile (EXP) progesterone (EXP) Pyridostigmine bromide (ISO) pyrimethanil (ISO) pyrrolidine dithiocarbamate (ISO) quercetin (EXP) quinoline (ISO) resveratrol (EXP,ISO) rotenone (EXP,ISO) rottlerin (ISO) SCH 23390 (ISO) senecionine (ISO) silicon dioxide (ISO) sodium arsenite (ISO) sodium dichromate (ISO) sodium dodecyl sulfate (ISO) sodium fluoride (ISO) Sophoricoside (ISO) sulpiride (ISO) tacrolimus hydrate (ISO) tadalafil (ISO) tamibarotene (ISO) Tesaglitazar (EXP) testosterone (EXP,ISO) tetrachloromethane (EXP,ISO) tetraphene (ISO) thioacetamide (EXP,ISO) titanium dioxide (ISO) tolcapone (EXP) toluene (EXP,ISO) topotecan (EXP) tributylstannane (EXP) trichloroethene (EXP) trimethyltin (ISO) triphenyl phosphate (ISO) tunicamycin (ISO) valproic acid (ISO) vincaleukoblastine (EXP) vincamine (ISO) zaragozic acid A (EXP,ISO) zinc atom (EXP) zinc(0) (EXP)
Biological Process
actin crosslink formation (ISO) actin filament bundle assembly (IBA,ISO,ISS) actin filament polymerization (ISO,ISS) cellular response to hormone stimulus (IEP) cellular response to hydroperoxide (IEP) cellular response to lipopolysaccharide (IEP) cellular response to morphine (IEP) cellular response to oxidative stress (ISO) cellular response to type II interferon (IEP,ISO) cerebellum development (IEP) inflammatory response (IEP) macrophage activation (NAS) negative regulation of apoptotic process (IDA,IMP) negative regulation of gene expression (IMP) negative regulation of smooth muscle cell chemotaxis (ISO) negative regulation of smooth muscle cell proliferation (ISO) parallel actin filament bundle assembly (ISO) phagocytosis, engulfment (ISO,ISS) positive regulation of cell migration (IDA,IMP,ISO) positive regulation of cell population proliferation (ISO) positive regulation of chemokine production (ISO) positive regulation of chemotaxis (ISO) positive regulation of fibroblast growth factor production (ISO) positive regulation of G1/S transition of mitotic cell cycle (ISO,ISS) positive regulation of interleukin-6 production (ISO) positive regulation of monocyte chemotaxis (ISO,ISS) positive regulation of mononuclear cell migration (ISO) positive regulation of muscle hyperplasia (IMP) positive regulation of nitric oxide biosynthetic process (IDA,IMP) positive regulation of protein phosphorylation (IMP) positive regulation of smooth muscle cell chemotaxis (ISO,ISS) positive regulation of smooth muscle cell proliferation (IMP,ISO,ISS) positive regulation of T cell migration (ISO,ISS) positive regulation of T cell proliferation (ISO,ISS) Rac protein signal transduction (ISO,ISS) response to axon injury (IEP) response to cytokine (IEP) response to electrical stimulus (IEP) response to glucocorticoid (IEP) ruffle assembly (IBA,ISO,ISS)
Cellular Component
actin filament (IBA,ISO,ISS) cell projection (IDA,IEA) cytoplasm (IDA,IEA,ISO) cytoskeleton (IEA) cytosol (ISO,ISS) glial cell projection (ISO) lamellipodium (IDA,ISO,ISS) membrane (IEA) nucleus (ISO,ISS) perikaryon (IDA) perinuclear region of cytoplasm (ISO) phagocytic cup (IEA,ISO,ISS) plasma membrane (IEA) ruffle (ISO) ruffle membrane (IBA,IEA,ISO,ISS)
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Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
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Electronic Transfer of LocusLink and RefSeq Data
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RGD automated data pipeline
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ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
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Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
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Aif1 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 20 3,651,435 - 3,657,341 (+) NCBI GRCr8 mRatBN7.2 20 3,646,784 - 3,652,670 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 20 3,646,777 - 3,652,668 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 20 4,350,088 - 4,351,997 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 20 3,712,144 - 3,714,054 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 20 4,249,928 - 4,251,828 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 20 5,161,350 - 5,167,176 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 5,161,333 - 5,166,448 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 20 7,234,609 - 7,240,454 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 20 3,714,428 - 3,716,327 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 20 3,714,654 - 3,716,552 NCBI Celera 20 4,373,127 - 4,375,026 (-) NCBI Celera Cytogenetic Map 20 p12 NCBI
AIF1 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 6 31,615,234 - 31,617,015 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 6 31,615,217 - 31,617,021 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 6 31,583,011 - 31,584,792 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 6 31,691,012 - 31,692,777 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 6 31,691,767 - 31,692,777 NCBI Celera 6 33,181,222 - 33,183,026 (+) NCBI Celera Cytogenetic Map 6 p21.33 NCBI HuRef 6 31,369,335 - 31,370,975 (+) NCBI HuRef CHM1_1 6 31,585,130 - 31,586,934 (+) NCBI CHM1_1 T2T-CHM13v2.0 6 31,468,284 - 31,470,065 (+) NCBI T2T-CHM13v2.0
Aif1 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 17 35,389,967 - 35,394,977 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 17 35,389,967 - 35,395,044 (-) Ensembl GRCm39 Ensembl GRCm38 17 35,170,986 - 35,176,083 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 17 35,170,991 - 35,176,068 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 17 35,307,937 - 35,312,946 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 17 34,779,048 - 34,784,057 (-) NCBI MGSCv36 mm8 Celera 17 38,267,928 - 38,272,936 (-) NCBI Celera Cytogenetic Map 17 B1 NCBI cM Map 17 18.59 NCBI
Aif1 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955437 157,509 - 158,919 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955437 157,509 - 158,919 (+) NCBI ChiLan1.0 ChiLan1.0
AIF1 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 5 46,092,079 - 46,093,913 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 6 42,053,651 - 42,055,477 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 6 31,276,215 - 31,278,051 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 6 32,166,301 - 32,168,125 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 6 32,166,301 - 32,168,125 (+) Ensembl panpan1.1 panPan2
AIF1 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 12 1,104,350 - 1,106,179 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 12 1,104,394 - 1,106,177 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 12 1,240,799 - 1,242,629 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 12 1,249,600 - 1,251,430 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 12 1,249,645 - 1,251,403 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 12 1,108,905 - 1,110,735 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 12 1,176,225 - 1,178,056 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 12 1,243,086 - 1,244,917 (+) NCBI UU_Cfam_GSD_1.0
Aif1 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024404946 35,651,964 - 35,653,851 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936727 1,907,505 - 1,909,338 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936727 1,907,493 - 1,909,350 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
AIF1 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 7 23,728,726 - 23,731,675 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 7 23,711,752 - 23,731,191 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 7 27,520,797 - 27,540,237 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
AIF1 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Vero_WHO_p1.0 NW_023666044 31,525,412 - 31,527,245 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Aif1
.
Predicted Target Of
Count of predictions: 115 Count of miRNA genes: 82 Interacting mature miRNAs: 88 Transcripts: ENSRNOT00000001135, ENSRNOT00000001138 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
61472 Aia1 Adjuvant induced arthritis QTL 1 18 0.001 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 20 2646395 4597031 Rat 2306850 Pia40 Pristane induced arthritis QTL 40 0.0001 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 20 1527959 5304575 Rat 1641915 Colcr9 Colorectal carcinoma resistance QTL 9 2.97 0.0024 intestine integrity trait (VT:0010554) benign colorectal tumor number (CMO:0001795) 20 1530655 46530655 Rat 2317057 Aia27 Adjuvant induced arthritis QTL 27 2.83 joint integrity trait (VT:0010548) right rear ankle joint diameter (CMO:0002150) 20 2892597 26381954 Rat 7387283 Uae44 Urinary albumin excretion QTL 44 0.1712 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 20 1 26123605 Rat 7411668 Foco32 Food consumption QTL 32 8 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 20 1 36600972 Rat 2305926 Iddm37 Insulin dependent diabetes mellitus QTL 37 6 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 20 1527842 46527842 Rat 1354642 Despr15 Despair related QTL 15 0.0027 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 20 1 24159021 Rat 1600382 Edcs3 Endometrial carcinoma susceptibility QTL3 3.5 0.003 uterus morphology trait (VT:0001120) percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759) 20 1 25159026 Rat 61448 Ciaa1 CIA Autoantibody QTL 1 30 0.001 blood autoantibody amount (VT:0003725) calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281) 20 2646395 4597031 Rat 1331772 Cdexp2 CD45RC expression in CD8 T cells QTL 2 5.7 CD8-positive T cell quantity (VT:0008077) blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990) 20 3621649 10078919 Rat 8694189 Bw153 Body weight QTL 153 3.13 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 20 1 29191651 Rat 1300152 Bp195 Blood pressure QTL 195 3.46 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 20 3621649 9243559 Rat 9590109 Sffal8 Serum free fatty acids level QTL 8 5.32 0.01 blood free fatty acid amount (VT:0001553) plasma free fatty acids level (CMO:0000546) 20 1 29191651 Rat 9590275 Scort15 Serum corticosterone level QTL 15 3.48 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 20 1 29191651 Rat 9589155 Insul32 Insulin level QTL 32 6.38 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 20 1 29191651 Rat 7411650 Foco23 Food consumption QTL 23 20.7 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 20 1 29191651 Rat 2317851 Alcrsp22 Alcohol response QTL 22 3.2 0.05 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 20 1 27339237 Rat 1598816 Memor12 Memory QTL 12 2.4 exploratory behavior trait (VT:0010471) average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674) 20 2606836 47606836 Rat 61432 Cia1 Collagen induced arthritis QTL 1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 20 3621656 14101050 Rat 1641893 Alcrsp7 Alcohol response QTL 7 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 20 1 27339237 Rat 6893685 Bw111 Body weight QTL 111 2.7 0.004 body mass (VT:0001259) body weight (CMO:0000012) 20 1 32578807 Rat 9590252 Scort12 Serum corticosterone level QTL 12 20.46 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 20 1 36600972 Rat 737973 Pia21 Pristane induced arthritis QTL 21 4.8 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 20 3621656 4606812 Rat
RH135373
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 20 3,656,581 - 3,657,308 (+) Marker Load Pipeline mRatBN7.2 20 3,651,910 - 3,652,637 (-) MAPPER mRatBN7.2 Rnor_6.0 20 5,161,383 - 5,162,109 NCBI Rnor6.0 Rnor_5.0 20 7,234,642 - 7,235,368 UniSTS Rnor5.0 RGSC_v3.4 20 3,715,568 - 3,716,294 UniSTS RGSC3.4 Celera 20 4,373,160 - 4,373,886 UniSTS RH 3.4 Map 20 53.6 UniSTS Cytogenetic Map 20 p12 UniSTS
MARC_5857-5858:997299374:1
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 20 3,651,240 - 3,651,828 (-) MAPPER mRatBN7.2 Rnor_6.0 20 5,162,192 - 5,162,779 NCBI Rnor6.0 Rnor_5.0 20 7,235,451 - 7,236,038 UniSTS Rnor5.0 RGSC_v3.4 20 3,714,898 - 3,715,485 UniSTS RGSC3.4 Celera 20 4,373,969 - 4,374,556 UniSTS Cytogenetic Map 20 p12 UniSTS
Aif1
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 20 3,655,730 - 3,656,489 (+) Marker Load Pipeline mRatBN7.2 20 3,651,059 - 3,651,818 (-) MAPPER mRatBN7.2 Rnor_6.0 20 5,162,202 - 5,162,960 NCBI Rnor6.0 Rnor_5.0 20 7,235,461 - 7,236,219 UniSTS Rnor5.0 RGSC_v3.4 20 3,714,717 - 3,715,475 UniSTS RGSC3.4 Celera 20 4,373,979 - 4,374,737 UniSTS Cytogenetic Map 20 p12 UniSTS
This gene Aif1 is modified in the following models/strains:
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000001135 ⟹ ENSRNOP00000001135
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 20 3,650,771 - 3,652,668 (+) Ensembl Rnor_6.0 Ensembl 20 5,161,356 - 5,163,247 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000001138 ⟹ ENSRNOP00000001138
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 20 3,649,975 - 3,652,668 (+) Ensembl Rnor_6.0 Ensembl 20 5,161,333 - 5,166,252 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000076331 ⟹ ENSRNOP00000068279
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 20 3,647,572 - 3,652,668 (+) Ensembl Rnor_6.0 Ensembl 20 5,161,350 - 5,166,448 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000076979
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 20 3,650,360 - 3,652,668 (+) Ensembl Rnor_6.0 Ensembl 20 5,161,350 - 5,163,660 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000097547 ⟹ ENSRNOP00000085491
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 20 3,646,777 - 3,652,668 (+) Ensembl
RefSeq Acc Id:
NM_017196 ⟹ NP_058892
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 3,655,442 - 3,657,341 (+) NCBI mRatBN7.2 20 3,650,771 - 3,652,670 (+) NCBI Rnor_6.0 20 5,161,350 - 5,163,249 (-) NCBI Rnor_5.0 20 7,234,609 - 7,240,454 (-) NCBI RGSC_v3.4 20 3,714,428 - 3,716,327 (+) RGD Celera 20 4,373,127 - 4,375,026 (-) RGD
Sequence:
CCAGAAGGGACTGGGGAGCTGGTGGAGAGAGGAGCCAGCCAACACACTGCAGCCTCATCGTCATCTCCCCACCTAAGGCCACCAGCGTCTGAGGAGCTATGAGCCAGAGCAAGGATTTGCAGGGAGGA
hide sequence
RefSeq Acc Id:
XM_006256065 ⟹ XP_006256127
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 3,652,201 - 3,657,341 (+) NCBI mRatBN7.2 20 3,647,577 - 3,652,670 (+) NCBI Rnor_6.0 20 5,161,350 - 5,166,443 (-) NCBI Rnor_5.0 20 7,234,609 - 7,240,454 (-) NCBI
Sequence:
CCTGTATGGCTTTCCCATCACAGGTCATTTGAGAGCTGGCCTGTGGGCTACTGACAGAAAGAAA
hide sequence
RefSeq Acc Id:
XM_039098495 ⟹ XP_038954423
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 3,652,422 - 3,657,341 (+) NCBI mRatBN7.2 20 3,647,751 - 3,652,670 (+) NCBI
RefSeq Acc Id:
XM_063279015 ⟹ XP_063135085
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 3,651,435 - 3,657,341 (+) NCBI
RefSeq Acc Id:
NP_058892 ⟸ NM_017196
- UniProtKB:
P55007 (UniProtKB/Swiss-Prot), P70491 (UniProtKB/Swiss-Prot), P55009 (UniProtKB/Swiss-Prot), A6KTW2 (UniProtKB/TrEMBL)
- Sequence:
MSQSKDLQGGKAFGLLKAQQEERLDGINKHFLDDPKYSSDEDLQSKLEAFKTKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIREVSSGSEETFSYSDFLRMMLGKRSAILRMILMYEEKN
hide sequence
RefSeq Acc Id:
XP_006256127 ⟸ XM_006256065
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2JT08 (UniProtKB/TrEMBL), A6KTW0 (UniProtKB/TrEMBL)
- Sequence:
MKPEEISRGKAFGLLKAQQEERLDGINKHFLDDPKYSSDEDLQSKLEAFKTKYMEFDLNGNGDI
hide sequence
Ensembl Acc Id:
ENSRNOP00000068279 ⟸ ENSRNOT00000076331
Ensembl Acc Id:
ENSRNOP00000001135 ⟸ ENSRNOT00000001135
Ensembl Acc Id:
ENSRNOP00000001138 ⟸ ENSRNOT00000001138
RefSeq Acc Id:
XP_038954423 ⟸ XM_039098495
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2JT08 (UniProtKB/TrEMBL), A6KTW0 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSRNOP00000085491 ⟸ ENSRNOT00000097547
RefSeq Acc Id:
XP_063135085 ⟸ XM_063279015
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2JT08 (UniProtKB/TrEMBL), A6KTW0 (UniProtKB/TrEMBL)
RGD ID: 13701399 Promoter ID: EPDNEW_R11923 Type: initiation region Name: Aif1_1 Description: allograft inflammatory factor 1 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Alternative Promoters: null; see alsoEPDNEW_R11924 Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 20 5,163,247 - 5,163,307 EPDNEW
RGD ID: 13701401 Promoter ID: EPDNEW_R11924 Type: initiation region Name: Aif1_2 Description: allograft inflammatory factor 1 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Alternative Promoters: null; see alsoEPDNEW_R11923 Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 20 5,166,223 - 5,166,283 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2006-04-06
Aif1
allograft inflammatory factor 1
Bart1
balloon angioplasty responsive transcript
Data merged from RGD:621212
737654 APPROVED
2002-08-07
Bart1
balloon angioplasty responsive transcript
Symbol and Name status set to provisional
70820 PROVISIONAL
2002-06-10
Aif1
allograft inflammatory factor 1
Name updated
70584 APPROVED
Note Type
Note
Reference
gene_domains
contains two strongly hydrophilic and one hydrophobic region, suggesting a type II integral membrane protein
632014
gene_mapping
found within the rat major histocompatibility RT1 complex
1300431
gene_process
may play a role in macrophage activation and function
724707
gene_regulation
transiently expressed in response to vascular trauma
632014
gene_regulation
transiently expressed in response to vascular trauma
632015
