Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Rps18 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RPS18 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Rps18 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RPS18 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of RPS18 mRNA | CTD | PMID:20551477 | 17alpha-ethynylestradiol | multiple interactions | ISO | Rps18 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RPS18 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | Rps18 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of RPS18 mRNA | CTD | PMID:17942748 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Rps18 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RPS18 mRNA | CTD | PMID:16466705 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RPS18 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Rps18 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of RPS18 mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RPS18 mRNA | CTD | PMID:16214954 and PMID:17942748 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of RPS18 mRNA | CTD | PMID:28522335 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of RPS18 mRNA more ... | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Rps18 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of RPS18 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RPS18 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of RPS18 protein | CTD | PMID:34186270 | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of RPS18 mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of RPS18 mRNA | CTD | PMID:19483382 | amino acid | multiple interactions | ISO | Rps18 (Mus musculus) | 6480464 | [EIF2AK4 gene mutant form affects the susceptibility to Amino Acids deficiency] which results in increased expression of RPS18 protein | CTD | PMID:29449374 | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of RPS18 mRNA | CTD | PMID:19483382 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of RPS18 mRNA | CTD | PMID:16483693 | antimycin A | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | Antimycin A results in increased expression of RPS18 mRNA | CTD | PMID:33512557 | arsane | decreases ubiquitination | ISO | RPS18 (Homo sapiens) | 6480464 | Arsenic results in decreased ubiquitination of RPS18 protein | CTD | PMID:35994080 | arsane | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS18 mRNA | CTD | PMID:35809665 | arsenic atom | decreases ubiquitination | ISO | RPS18 (Homo sapiens) | 6480464 | Arsenic results in decreased ubiquitination of RPS18 protein | CTD | PMID:35994080 | arsenic atom | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS18 mRNA | CTD | PMID:35809665 | arsenic trichloride | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [arsenic trichloride results in increased abundance of Arsenic] which results in decreased expression of RPS18 mRNA | CTD | PMID:35809665 | arsenite(3-) | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to RPS18 mRNA] | CTD | PMID:32406909 | azoxystrobin | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | azoxystrobin results in increased expression of RPS18 mRNA | CTD | PMID:33512557 | benzalkonium chloride | affects response to substance | ISO | RPS18 (Homo sapiens) | 6480464 | RPS18 SNP affects the susceptibility to Benzalkonium Compounds | CTD | PMID:27258892 | benzatropine | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in decreased expression of RPS18 protein | CTD | PMID:34122009 | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of RPS18 mRNA | CTD | PMID:19483382 | benzo[a]pyrene | increases expression | ISO | Rps18 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RPS18 mRNA | CTD | PMID:20504355 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RPS18 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RPS18 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RPS18 protein | CTD | PMID:34186270 and PMID:37567409 | bisphenol A | increases expression | ISO | Rps18 (Mus musculus) | 6480464 | bisphenol A results in increased expression of RPS18 mRNA | CTD | PMID:32156529 more ... | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RPS18 mRNA | CTD | PMID:33296240 | bisphenol A | decreases expression | ISO | Rps18 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of RPS18 mRNA | CTD | PMID:29165653 | bisphenol A | affects expression | ISO | RPS18 (Homo sapiens) | 6480464 | bisphenol A affects the expression of RPS18 mRNA | CTD | PMID:30903817 | bisphenol A | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of RPS18 mRNA | CTD | PMID:28628672 | Bisphenol B | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of RPS18 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RPS18 mRNA | CTD | PMID:28628672 | bisphenol F | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of RPS18 protein | CTD | PMID:34186270 | caffeine | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | Caffeine results in increased expression of RPS18 protein | CTD | PMID:31195006 | carbon nanotube | increases expression | ISO | Rps18 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of RPS18 mRNA | CTD | PMID:25620056 | chloropicrin | affects expression | ISO | RPS18 (Homo sapiens) | 6480464 | chloropicrin affects the expression of RPS18 mRNA | CTD | PMID:26352163 | cisplatin | affects response to substance | ISO | RPS18 (Homo sapiens) | 6480464 | RPS18 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | clobetasol | increases expression | ISO | Rps18 (Mus musculus) | 6480464 | Clobetasol results in increased expression of RPS18 mRNA | CTD | PMID:27462272 | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of RPS18 mRNA | CTD | PMID:19483382 | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RPS18 mRNA | CTD | PMID:17602206 | Cuprizon | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Benztropine] results in decreased expression of RPS18 protein | CTD | PMID:34122009 | cypermethrin | decreases expression | ISO | Rps18 (Mus musculus) | 6480464 | cypermethrin results in decreased expression of RPS18 mRNA | CTD | PMID:29020013 | deguelin | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | deguelin results in increased expression of RPS18 mRNA | CTD | PMID:33512557 | dexamethasone | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of RPS18 mRNA more ... | CTD | PMID:28628672 | dihydroartemisinin | affects binding | ISO | RPS18 (Homo sapiens) | 6480464 | artenimol analog binds to RPS18 protein | CTD | PMID:26340163 | dioxygen | decreases expression | ISO | Rps18 (Mus musculus) | 6480464 | Oxygen deficiency results in decreased expression of RPS18 mRNA | CTD | PMID:24205000 | ethanol | affects expression | ISO | Rps18 (Mus musculus) | 6480464 | Ethanol affects the expression of RPS18 mRNA | CTD | PMID:26730594 | fenpyroximate | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | fenpyroximate results in increased expression of RPS18 mRNA | CTD | PMID:33512557 | folic acid | multiple interactions | ISO | Rps18 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RPS18 mRNA | CTD | PMID:22206623 | genistein | decreases expression | ISO | RPS18 (Homo sapiens) | 6480464 | Genistein results in decreased expression of RPS18 protein | CTD | PMID:20884965 | genistein | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | ESR1 promotes the reaction [Genistein results in decreased expression of RPS18 protein] | CTD | PMID:20884965 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of RPS18 mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of RPS18 mRNA more ... | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | RPS18 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RPS18 protein | CTD | PMID:32959892 | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of RPS18 mRNA | CTD | PMID:19483382 | lead diacetate | decreases expression | ISO | Rps18 (Mus musculus) | 6480464 | lead acetate results in decreased expression of RPS18 mRNA | CTD | PMID:22609695 | miconazole | increases expression | ISO | Rps18 (Mus musculus) | 6480464 | Miconazole results in increased expression of RPS18 mRNA | CTD | PMID:27462272 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of RPS18 mRNA | CTD | PMID:17602206 | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of RPS18 mRNA | CTD | PMID:19483382 | paracetamol | affects expression | ISO | Rps18 (Mus musculus) | 6480464 | Acetaminophen affects the expression of RPS18 mRNA | CTD | PMID:17562736 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Rps18 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RPS18 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of RPS18 mRNA | CTD | PMID:36331819 | picoxystrobin | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | picoxystrobin results in increased expression of RPS18 mRNA | CTD | PMID:33512557 | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of RPS18 mRNA | CTD | PMID:19483382 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Rps18 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of RPS18 mRNA | CTD | PMID:22698814 and PMID:28903501 | pyrimidifen | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | pyrimidifen results in increased expression of RPS18 mRNA | CTD | PMID:33512557 | rotenone | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | Rotenone results in increased expression of RPS18 mRNA | CTD | PMID:33512557 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of RPS18 protein | CTD | PMID:35544339 | SB 431542 | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of RPS18 protein | CTD | PMID:37664457 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of RPS18 mRNA | CTD | PMID:18685790 | sodium arsenite | multiple interactions | ISO | RPS18 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of and results in increased activity of RPS18 protein | CTD | PMID:30528433 | sunitinib | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of RPS18 mRNA | CTD | PMID:31533062 | tebufenpyrad | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of RPS18 mRNA | CTD | PMID:33512557 | temozolomide | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of RPS18 mRNA | CTD | PMID:31758290 | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of RPS18 mRNA | CTD | PMID:19483382 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of RPS18 mRNA | CTD | PMID:14565619 | tris(2-butoxyethyl) phosphate | increases expression | ISO | RPS18 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate results in increased expression of RPS18 mRNA | CTD | PMID:29024780 | tungsten | increases expression | ISO | Rps18 (Mus musculus) | 6480464 | Tungsten results in increased expression of RPS18 mRNA | CTD | PMID:30912803 | valproic acid | increases methylation | ISO | RPS18 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of RPS18 gene | CTD | PMID:29154799 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of RPS18 mRNA | CTD | PMID:23034163 | |