Gene:	Mmp7 ( Rattus norvegicus ) matrix metallopeptidase 7
Description:	enzyme that cleaves the alpha 2(I) chain of rat gelatin
Synonyms:	Matrix metalloproteinase 7 (matrilysin); MPMM; matrix metalloproteinase 7;  (details...)
ArrayIDs:	1368766_at; 6450213; L24374_at; 5679761; A_43_P11590; 6168164; 6410494; 5792285; 6701099; 6118716; 6285297; 6736213; 6679226; GE1133863; 6724063;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: MMP7     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Mmp7     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Mmp7 genome assembly 3.1 8 4526033 - 4533729     Rat Celera Assembly 8 6407558 - 6432828     RGSC genome assembly v3.4 8 4526034 - 4551303     Cytogenetic 8 q11 Mus musculus Mmp7 Mouse genome assembly build 36.1 9 7692094 - 7699580     Cytogenetic 9 9 A1 Homo sapiens MMP7 human genome assembly 11 101896448 - 101906688     Human genome assembly build 36.2 11 101896449 - 101906688     Cytogenetic 11 q21-q22   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Note Reference cleaves and activates latent human interstitial collagenase 1 728999 Gene Ontology zinc ion binding,  peptidase activity,  calcium ion binding ...  (details...)
Biological Process	Gene Ontology metabolic process,  regulation of cell proliferation,  proteolysis ...  (details...)
Cellular Component	Gene Ontology extracellular region,  proteinaceous extracellular matrix (details...)
Disease	Ontology Prostatic Neoplasms,  Endometrial Neoplasms,  Endometrial Hyperplasia ...  (details...)
External Links
Databases	DATABASE ID SOURCE SMART: ZnMc IPI PROSITE: CYSTEINE_SWITCH IPI UNIPARC: UPI000012F244 IPI KEGG Report: rno:25335 ENTREZGENE HomoloGene Group ID: 37619 ENTREZGENE Germonline: 3100 Pfam: Peptidase_M10 IPI Pfam: PG_binding_1 IPI KEGG Pathway: 04310 ENTREZGENE InterPro: Peptidoglycan-bd-like. IPI InterPro: Peptidase_M. IPI InterPro: Pept_M10A_M12B. IPI Ensembl Protein: ENSRNOP00000014041 IPI IPI: IPI00196590 IPI Entrez Gene: Mmp7 ENTREZGENE IMAGE_CLONE: IMAGE:5623517 IMAGE-MGC_LOAD MGC_CLONE: MGC:72527 IMAGE-MGC_LOAD Ensembl Genes: ENSRNOG00000010507 IPI TIGR: TC209815 UniProt: MMP7_RAT IPI Superfamily-SCOP: PGBD_like IPI RatMap: 41220 ENTREZGENE PRINTS: MATRIXIN. IPI
Sequences	Nucleotide: X07821 Get FASTA Search GEO Profiles Nucleotide: X07822 Get FASTA Search GEO Profiles Nucleotide: CH473993 Get FASTA Search GEO Profiles Nucleotide: BC064657 Get FASTA Search GEO Profiles Nucleotide: NM_012864 Get FASTA Search GEO Profiles Nucleotide: L24374 Get FASTA Search GEO Profiles (View all 6 Nucleotide Accessions) Protein: AAA99432 Get FASTA Protein: EDL78525 Get FASTA Protein: NP_036996 Get FASTA Protein: P50280 Get FASTA Protein: AAH64657 Get FASTA (View all 5 Protein Accessions)
Clusters	UniGene: 10282
References
Curated References	18 references in RGD related to Mmp7
Other References	20 other references at PubMed related to Mmp7
Database Information
RGD ID	3100
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 30-MAR-06: Mmp7 matrix metallopeptidase 7 matrix metalloproteinase 7 APPROVED Name updated 1299863 10-JUN-02: Mmp7 Matrix metalloproteinase 7 (matrilysin) APPROVED Symbol and Name status set to approved 70586