Fgf18 (fibroblast growth factor 18) - Rat Genome Database

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Gene: Fgf18 (fibroblast growth factor 18) Rattus norvegicus
Analyze
Symbol: Fgf18
Name: fibroblast growth factor 18
RGD ID: 2608
Description: Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in nervous system development and positive regulation of hepatocyte proliferation. Located in cytoplasm and nucleus. Orthologous to human FGF18 (fibroblast growth factor 18); PARTICIPATES IN fibroblast growth factor signaling pathway; melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH all-trans-retinoic acid; alpha-Zearalanol; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FGF-18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81018,210,240 - 18,241,929 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1018,210,512 - 18,240,933 (-)EnsemblGRCr8
mRatBN7.21017,706,011 - 17,737,702 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,706,174 - 17,736,818 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1022,455,024 - 22,484,592 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,943,626 - 21,973,192 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01017,432,271 - 17,461,845 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01018,047,109 - 18,082,290 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1018,047,109 - 18,063,391 (-)Ensemblrn6Rnor6.0
Rnor_5.01017,932,880 - 17,967,318 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera1017,348,236 - 17,383,370 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-taxifolin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-methylcholanthrene  (ISO)
3-Nitrobenzanthrone  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
chlorpyrifos  (EXP)
chondroitin sulfate  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dermatan sulfate  (ISO)
dextran sulfate  (ISO)
diethyl malate  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
fluoranthene  (ISO)
fulvestrant  (ISO)
Glutathione ethyl ester  (ISO)
lead diacetate  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
methylmercury chloride  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nickel atom  (EXP)
nitrofen  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
Nutlin-3  (ISO)
ochratoxin A  (EXP,ISO)
okadaic acid  (ISO)
panobinostat  (ISO)
pentanal  (ISO)
perfluorooctanoic acid  (EXP)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Theaflavin 3,3'-digallate  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Fibroblast growth factor 16 and 18 are expressed in human cardiovascular tissues and induce on endothelial cells migration but not proliferation. Antoine M, etal., Biochem Biophys Res Commun. 2006 Jul 21;346(1):224-33. Epub 2006 May 26.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Structure and expression of the mRNA encoding a novel fibroblast growth factor, FGF-18. Ohbayashi N, etal., J Biol Chem 1998 Jul 17;273(29):18161-4.
7. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:11741978   PMID:11937493   PMID:11937494   PMID:12738892   PMID:15252029   PMID:15336546   PMID:15447937   PMID:15781473   PMID:16019430   PMID:16384934   PMID:17014841   PMID:23979401  
PMID:25449503  


Genomics

Comparative Map Data
Fgf18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81018,210,240 - 18,241,929 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1018,210,512 - 18,240,933 (-)EnsemblGRCr8
mRatBN7.21017,706,011 - 17,737,702 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,706,174 - 17,736,818 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1022,455,024 - 22,484,592 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,943,626 - 21,973,192 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01017,432,271 - 17,461,845 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01018,047,109 - 18,082,290 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1018,047,109 - 18,063,391 (-)Ensemblrn6Rnor6.0
Rnor_5.01017,932,880 - 17,967,318 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera1017,348,236 - 17,383,370 (-)NCBICelera
Cytogenetic Map10q12NCBI
FGF18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385171,419,647 - 171,457,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5171,419,645 - 171,457,626 (+)Ensemblhg38GRCh38
GRCh375170,846,651 - 170,884,630 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365170,779,272 - 170,816,781 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345170,779,271 - 170,816,781NCBI
Celera5166,879,014 - 166,916,982 (+)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5165,944,447 - 165,981,862 (+)NCBIHuRef
CHM1_15170,279,191 - 170,317,159 (+)NCBICHM1_1
T2T-CHM13v2.05171,959,977 - 171,997,979 (+)NCBIT2T-CHM13v2.0
Fgf18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,066,970 - 33,097,400 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,067,430 - 33,097,400 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381133,116,970 - 33,147,400 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,117,430 - 33,147,400 (-)Ensemblmm10GRCm38
MGSCv371133,017,430 - 33,047,400 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361133,017,430 - 33,047,400 (-)NCBIMGSCv36mm8
Celera1135,529,642 - 35,559,689 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.21NCBI
Fgf18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540824,225,459 - 24,260,092 (+)Ensembl
ChiLan1.0NW_00495540824,225,459 - 24,260,057 (+)NCBIChiLan1.0ChiLan1.0
FGF18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24166,553,461 - 166,591,129 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15164,693,000 - 164,730,916 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05166,765,061 - 166,802,277 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FGF18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,714,891 - 40,748,892 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,715,060 - 40,748,518 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha440,660,286 - 40,697,075 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0441,089,249 - 41,126,052 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl441,091,859 - 41,126,139 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,904,218 - 40,941,026 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0441,094,435 - 41,131,275 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0441,604,558 - 41,641,375 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fgf18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,954,910 - 94,983,832 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366093,677,237 - 3,706,517 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366093,677,661 - 3,706,511 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1652,725,356 - 52,759,791 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11652,724,867 - 52,760,246 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,920,916 - 56,956,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12373,584,223 - 73,620,881 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2373,584,766 - 73,620,069 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660345,019,198 - 5,060,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473318,599,557 - 18,633,016 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473318,599,186 - 18,633,065 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fgf18
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v195,945,375 - 5,975,364 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fgf18
286 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:24
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000072297
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
737823Alc12Alcohol consumption QTL 124.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101774978420796344Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101576223019737486Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 148 79 78 47 74 47 6 325 174 11 125 80 92 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000072297   ⟹   ENSRNOP00000064983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1018,210,512 - 18,227,955 (-)Ensembl
mRatBN7.2 Ensembl1017,706,174 - 17,723,728 (-)Ensembl
Rnor_6.0 Ensembl1018,047,109 - 18,063,391 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103123   ⟹   ENSRNOP00000084264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1018,210,512 - 18,240,933 (-)Ensembl
mRatBN7.2 Ensembl1017,706,174 - 17,736,818 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000128641   ⟹   ENSRNOP00000112106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1018,210,512 - 18,240,595 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000165492   ⟹   ENSRNOP00000101477
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1018,210,512 - 18,232,293 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000167374   ⟹   ENSRNOP00000111106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1018,210,512 - 18,230,202 (-)Ensembl
RefSeq Acc Id: NM_019199   ⟹   NP_062072
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81018,210,497 - 18,240,882 (-)NCBI
mRatBN7.21017,706,268 - 17,736,655 (-)NCBI
Rnor_6.01018,047,109 - 18,082,290 (-)NCBI
Rnor_5.01017,932,880 - 17,967,318 (-)NCBI
Celera1017,348,236 - 17,383,370 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085733   ⟹   XP_038941661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81018,211,404 - 18,241,929 (-)NCBI
mRatBN7.21017,707,168 - 17,737,702 (-)NCBI
RefSeq Acc Id: XM_039085734   ⟹   XP_038941662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81018,210,240 - 18,240,493 (-)NCBI
mRatBN7.21017,706,011 - 17,736,275 (-)NCBI
RefSeq Acc Id: XM_039085735   ⟹   XP_038941663
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81018,210,240 - 18,241,918 (-)NCBI
mRatBN7.21017,706,011 - 17,737,692 (-)NCBI
RefSeq Acc Id: XR_005489768
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81018,211,404 - 18,241,919 (-)NCBI
mRatBN7.21017,707,168 - 17,737,692 (-)NCBI
RefSeq Acc Id: NP_062072   ⟸   NM_019199
- Peptide Label: precursor
- UniProtKB: O88182 (UniProtKB/Swiss-Prot),   M0R6D5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064983   ⟸   ENSRNOT00000072297
RefSeq Acc Id: XP_038941663   ⟸   XM_039085735
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038941662   ⟸   XM_039085734
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038941661   ⟸   XM_039085733
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000084264   ⟸   ENSRNOT00000103123
Ensembl Acc Id: ENSRNOP00000112106   ⟸   ENSRNOT00000128641
Ensembl Acc Id: ENSRNOP00000111106   ⟸   ENSRNOT00000167374
Ensembl Acc Id: ENSRNOP00000101477   ⟸   ENSRNOT00000165492

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88182-F1-model_v2 AlphaFold O88182 1-207 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2608 AgrOrtholog
BioCyc Gene G2FUF-25610 BioCyc
Ensembl Genes ENSRNOG00000048389 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000103123 ENTREZGENE
  ENSRNOT00000103123.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.80.10.50 UniProtKB/Swiss-Prot
InterPro Fibroblast_GF_fam UniProtKB/Swiss-Prot
  IL1/FGF UniProtKB/Swiss-Prot
KEGG Report rno:29369 UniProtKB/Swiss-Prot
NCBI Gene 29369 ENTREZGENE
PANTHER PTHR11486 UniProtKB/Swiss-Prot
Pfam FGF UniProtKB/Swiss-Prot
PhenoGen Fgf18 PhenoGen
PRINTS IL1HBGF UniProtKB/Swiss-Prot
PROSITE HBGF_FGF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000048389 RatGTEx
SMART FGF UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot
TIGR TC220071
UniProt A0ABK0LBI4_RAT UniProtKB/TrEMBL
  A0ABK0LJN9_RAT UniProtKB/TrEMBL
  A0ABK0M8M5_RAT UniProtKB/TrEMBL
  A6HDG1_RAT UniProtKB/TrEMBL
  FGF18_RAT UniProtKB/Swiss-Prot
  M0R6D5 ENTREZGENE, UniProtKB/TrEMBL
  O88182 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Fgf18  fibroblast growth factor 18      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expressed primarily in lung of adults 69834
gene_homology shares 99% aa sequence identity with human FGF18, and 99.5% with mouse Fgf18 69834