FGF18 (fibroblast growth factor 18) - Rat Genome Database

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Pathways
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Gene: FGF18 (fibroblast growth factor 18) Pan paniscus
Analyze
Symbol: FGF18
Name: fibroblast growth factor 18
RGD ID: 32733080
Description: ENCODES a protein that exhibits fibroblast growth factor receptor binding (inferred); growth factor activity (inferred); type 1 fibroblast growth factor receptor binding (inferred); INVOLVED IN angiogenesis (ortholog); cell population proliferation (ortholog); chondrocyte development (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; ASSOCIATED WITH Diaphragmatic Hernia (ortholog); Dwarfism (ortholog); hydrocephalus (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24166,553,461 - 166,591,129 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15164,693,000 - 164,730,916 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05166,765,061 - 166,802,277 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FGF18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24166,553,461 - 166,591,129 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15164,693,000 - 164,730,916 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05166,765,061 - 166,802,277 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FGF18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385171,419,647 - 171,457,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5171,419,647 - 171,457,626 (+)EnsemblGRCh38hg38GRCh38
GRCh375170,846,651 - 170,884,630 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365170,779,272 - 170,816,781 (+)NCBINCBI36Build 36hg18NCBI36
Build 345170,779,271 - 170,816,781NCBI
Celera5166,879,014 - 166,916,982 (+)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5165,944,447 - 165,981,862 (+)NCBIHuRef
CHM1_15170,279,191 - 170,317,159 (+)NCBICHM1_1
T2T-CHM13v2.05171,959,977 - 171,997,979 (+)NCBIT2T-CHM13v2.0
Fgf18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,066,970 - 33,097,400 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,067,430 - 33,097,400 (-)EnsemblGRCm39 Ensembl
GRCm381133,116,970 - 33,147,400 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,117,430 - 33,147,400 (-)EnsemblGRCm38mm10GRCm38
MGSCv371133,017,430 - 33,047,400 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361133,017,430 - 33,047,400 (-)NCBIMGSCv36mm8
Celera1135,529,642 - 35,559,689 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.21NCBI
Fgf18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81018,210,240 - 18,241,929 (-)NCBIGRCr8
mRatBN7.21017,706,011 - 17,737,702 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,706,174 - 17,736,818 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1022,455,024 - 22,484,592 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,943,626 - 21,973,192 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01017,432,271 - 17,461,845 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01018,047,109 - 18,082,290 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1018,047,109 - 18,063,391 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,932,880 - 17,967,318 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1017,348,236 - 17,383,370 (-)NCBICelera
Cytogenetic Map10q12NCBI
Fgf18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540824,225,459 - 24,260,092 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540824,225,459 - 24,260,057 (+)NCBIChiLan1.0ChiLan1.0
FGF18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,714,891 - 40,748,892 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,715,060 - 40,748,518 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha440,660,286 - 40,697,075 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0441,089,249 - 41,126,052 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl441,091,859 - 41,126,139 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,904,218 - 40,941,026 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0441,094,435 - 41,131,275 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0441,604,558 - 41,641,375 (-)NCBIUU_Cfam_GSD_1.0
Fgf18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,954,910 - 94,983,832 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366093,677,237 - 3,706,517 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366093,677,661 - 3,706,511 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1652,725,356 - 52,759,791 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11652,724,867 - 52,760,246 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,920,916 - 56,956,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12373,584,223 - 73,620,881 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2373,584,766 - 73,620,069 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660345,019,198 - 5,060,806 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473318,599,557 - 18,633,016 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473318,599,186 - 18,633,065 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034960959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_034960959   ⟹   XP_034816850
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24166,553,461 - 166,591,129 (+)NCBI
NHGRI_mPanPan15164,693,000 - 164,730,916 (+)NCBI
Mhudiblu_PPA_v05166,765,061 - 166,802,277 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034816850 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000042580.1
Reference Protein Sequences
RefSeq Acc Id: XP_034816850   ⟸   XM_034960959
- UniProtKB: A0A2R9CKR2 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043852 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000065510.1 UniProtKB/TrEMBL
Gene3D-CATH 2.80.10.50 UniProtKB/TrEMBL
InterPro Fibroblast_GF_fam UniProtKB/TrEMBL
  IL1/FGF UniProtKB/TrEMBL
NCBI Gene FGF18 ENTREZGENE
PANTHER FIBROBLAST GROWTH FACTOR UniProtKB/TrEMBL
  FIBROBLAST GROWTH FACTOR 18 UniProtKB/TrEMBL
Pfam FGF UniProtKB/TrEMBL
PRINTS IL1HBGF UniProtKB/TrEMBL
PROSITE HBGF_FGF UniProtKB/TrEMBL
SMART FGF UniProtKB/TrEMBL
Superfamily-SCOP Cytokine UniProtKB/TrEMBL
UniProt A0A2R9CKR2 ENTREZGENE, UniProtKB/TrEMBL