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Gene Ontology Annotations
Gene Ontology AnnotationsBiological Process Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | angiogenesis | | IMP | MGI:MGI:2178751 | 2290270 | MGI:MGI:3703411|PMID:17014841 | MGI | MGI:MGI:3703411 PMID:17014841 | chondrocyte development | | IMP | MGI:MGI:2178751 | 2290270 | MGI:MGI:3703411|PMID:17014841 | MGI | MGI:MGI:3703411 PMID:17014841 | endochondral ossification | | IMP | MGI:MGI:2178751 | 2290270 | MGI:MGI:3703411|PMID:17014841 | MGI | MGI:MGI:3703411 PMID:17014841 | fibroblast growth factor receptor signaling pathway | | IGI | MGI:MGI:95524 | 2290270 | MGI:MGI:3584218|PMID:15781473 | MGI | MGI:MGI:3584218 PMID:15781473 | intramembranous ossification | | IMP | MGI:MGI:2178751 | 2290270 | MGI:MGI:3703411|PMID:17014841 | MGI | MGI:MGI:3703411 PMID:17014841 | lung development | | IMP | MGI:MGI:2179607 | 2290270 | MGI:MGI:3051435|PMID:15336546 | MGI | MGI:MGI:3051435 PMID:15336546 | nervous system development | | ISO | UniProtKB:O88182 | 2290270 | MGI:MGI:4417868 | RGD | MGI:MGI:4417868 | ossification | | IMP | MGI:MGI:2178751 | 2290270 | MGI:MGI:2177990|PMID:11937493 | MGI | MGI:MGI:2177990 PMID:11937493 | ossification | | IMP | MGI:MGI:2179607 | 2290270 | MGI:MGI:2177991|PMID:11937494 | MGI | MGI:MGI:2177991 PMID:11937494 | positive regulation of cell proliferation | | IMP | MGI:MGI:2178751 | 2290270 | MGI:MGI:3703411|PMID:17014841 | MGI | MGI:MGI:3703411 PMID:17014841 | positive regulation of chondrocyte differentiation | | IGI | MGI:MGI:95524 | 2290270 | MGI:MGI:3584218|PMID:15781473 | MGI | MGI:MGI:3584218 PMID:15781473 | positive regulation of ERK1 and ERK2 cascade | | IDA | | 2290270 | MGI:MGI:2175916|PMID:11741978 | MGI | MGI:MGI:2175916 PMID:11741978 | positive regulation of vascular endothelial growth factor receptor signaling pathway | | IMP | MGI:MGI:2178751 | 2290270 | MGI:MGI:3703411|PMID:17014841 | MGI | MGI:MGI:3703411 PMID:17014841 | signal transduction | | TAS | | 2290270 | MGI:MGI:2177990|PMID:11937493 | MGI | MGI:MGI:2177990 PMID:11937493 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Pathway Annotations| External Database Links | |
| KEGG Pathway | MAPK signaling pathway |
| Melanoma | |
| Pathways in cancer | |
| PI3K-Akt signaling pathway | |
| Regulation of actin cytoskeleton | |
| Pathway Interaction Database | FGF signaling pathway (PID:200220) |
Phenotype Annotations
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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| External Database Links | |
| KEGG Pathway | MAPK signaling pathway |
| Melanoma | |
| Pathways in cancer | |
| PI3K-Akt signaling pathway | |
| Regulation of actin cytoskeleton | |
| Pathway Interaction Database | FGF signaling pathway (PID:200220) |
Phenotype Annotations
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References - curated| 1. |
MGD and Homologene mouse data transfer |
| 2. |
MGD data from the GO Consortium |
| 3. |
MGD IEA |
| 4. |
Ohbayashi N, etal., J Biol Chem 1998 Jul 17;273(29):18161-4. |
| 5. |
Okazaki Y, etal., Nature 2002 Dec 5;420(6915):563-73. |
| 6. |
Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology |
| 7. |
Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 8. |
RGD automated import pipeline |
| 9. |
RGD automated import pipeline for gene-chemical interactions |
References - uncurated| PubMed | 10349636 |
| 10499586 | |
| 10704889 | |
| 10751172 | |
| 10769235 | |
| 10906450 | |
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RGD Disease Portals| Fgf18 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Fgf18 (Mus musculus) |
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| FGF18 (Homo sapiens) |
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| Fgf18 (Rattus norvegicus) |
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Position Markers| Fgf18 |
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| AF075291 |
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| Fgf18 |
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| Fgf18 |
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| Fgf18 |
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QTLs in Region (Mouse Genome Assembly Build 37)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_008005 | (Get FASTA) | Search GEO for Microarray Profiles |
| NR_102395 | (Get FASTA) | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AAHY01092138 | (Get FASTA) | Search GEO for Microarray Profiles |
| AAHY01092139 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHY01092140 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB004639 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF075291 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF211187 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK051548 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK078245 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AL732390 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AL772409 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH466604 | (Get FASTA) | Search GEO for Microarray Profiles | |
| FB706735 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_008005 | |||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||
| Protein Acc Id: | NP_032031 | |||||||||||||||||||||||||
| Peptide Label: | precursor | |||||||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_032031 | (Get FASTA) |
| GenBank Protein | AAC62239 | (Get FASTA) |
| AAF22976 | (Get FASTA) | |
| AAI52853 | (Get FASTA) | |
| AAI56770 | (Get FASTA) | |
| BAA31980 | (Get FASTA) | |
| CAS03065 | (Get FASTA) | |
| EDL23745 | (Get FASTA) | |
| O89101 | (Get FASTA) |
Promoters| RGD ID: | 6820876 | ||||||||||
| Promoter ID: | MM_KWN:6900 | ||||||||||
| Type: | CpG-Island | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | 3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day4, BoneMarrow_0Hour, ES_Cell, Lung | ||||||||||
| Transcripts: | ENSMUST00000109363, OTTMUST00000012019 | ||||||||||
| Position: |
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSMUSG00000057967 | ENTREZGENE |
| Ensembl Protein | ENSMUSP00000020507 | ENTREZGENE |
| Ensembl Transcript | ENSMUST00000020507 | ENTREZGENE |
| Entrez Gene | 14172 | ENTREZGENE |
| Germonline | ENSMUSG00000057967 | |
| HomoloGene Group ID | 2867 | ENTREZGENE |
| InterPro | Cytokine_IL1-like | UniProtKB/Swiss-Prot |
| IL1_HBGF | UniProtKB/Swiss-Prot | |
| IPI | IPI00131494 | UniProtKB/Swiss-Prot |
| IPI00649239 | UniProtKB/TrEMBL | |
| KEGG Report | mmu:14172 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGD | MGI:1277980 | ENTREZGENE |
| PANTHER | IL1_HBGF | UniProtKB/Swiss-Prot |
| Pfam | FGF | UniProtKB/Swiss-Prot |
| PRINTS | IL1HBGF | UniProtKB/Swiss-Prot |
| PROSITE | HBGF_FGF | UniProtKB/Swiss-Prot |
| SMART | FGF | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | Cytok_IL1_like | UniProtKB/Swiss-Prot |
| UniGene | Mm.339812 | ENTREZGENE |
| UniProt | FGF18_MOUSE | UniProtKB/Swiss-Prot |
| Q5SQB3_MOUSE | UniProtKB/TrEMBL |
| More on Fgf18 | |
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Entrez Gene |
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Ensembl Gene |
![]() | Genome Browser |
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MGI Report |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 737084 |
| Created: | 2004-02-06 |
| Species: | Mus musculus |
| Last Modified: | 2013-04-09 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




