Rfc4 (replication factor C subunit 4) - Rat Genome Database

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Gene: Rfc4 (replication factor C subunit 4) Rattus norvegicus
Analyze
Symbol: Rfc4
Name: replication factor C subunit 4
RGD ID: 1310142
Description: Predicted to enable enzyme binding activity. Predicted to contribute to DNA clamp loader activity and single-stranded DNA helicase activity. Predicted to be involved in DNA repair and DNA-templated DNA replication. Predicted to be located in nucleoplasm. Predicted to be part of Ctf18 RFC-like complex; DNA replication factor C complex; and Elg1 RFC-like complex. Predicted to be active in nucleus. Orthologous to human RFC4 (replication factor C subunit 4); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; DNA replication pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC288003; replication factor C (activator 1) 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,254,273 - 91,268,727 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1191,254,243 - 91,268,730 (+)EnsemblGRCr8
mRatBN7.21177,749,642 - 77,764,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1177,749,638 - 77,764,122 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1186,500,114 - 86,514,569 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,137,786 - 79,152,227 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,214,412 - 78,228,869 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01181,358,592 - 81,373,044 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,358,592 - 81,373,043 (+)Ensemblrn6Rnor6.0
Rnor_5.01184,396,767 - 84,411,362 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41179,935,273 - 79,950,589 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1176,622,175 - 76,636,605 (+)NCBICelera
RGSC_v3.11179,992,852 - 80,008,178 (+)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-diaminotoluene  (ISO)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dieldrin  (EXP)
dioxygen  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
folic acid  (ISO)
furan  (EXP)
glyphosate  (ISO)
heptachlor  (EXP)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
ivermectin  (ISO)
Lasiocarpine  (ISO)
leflunomide  (ISO)
menadione  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
mirex  (EXP)
mitomycin C  (ISO)
monocrotaline  (ISO)
nickel subsulfide  (ISO)
Nutlin-3  (ISO)
ochratoxin A  (EXP,ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
riddelliine  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetrahydropalmatine  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Replication clamps and clamp loaders. Hedglin M, etal., Cold Spring Harb Perspect Biol. 2013 Apr 1;5(4):a010165. doi: 10.1101/cshperspect.a010165.
4. Mechanisms and functions of DNA mismatch repair. Li GM Cell Res. 2008 Jan;18(1):85-98.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9488738   PMID:12477932   PMID:12930902   PMID:23277426   PMID:24115439  


Genomics

Comparative Map Data
Rfc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,254,273 - 91,268,727 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1191,254,243 - 91,268,730 (+)EnsemblGRCr8
mRatBN7.21177,749,642 - 77,764,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1177,749,638 - 77,764,122 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1186,500,114 - 86,514,569 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,137,786 - 79,152,227 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,214,412 - 78,228,869 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01181,358,592 - 81,373,044 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,358,592 - 81,373,043 (+)Ensemblrn6Rnor6.0
Rnor_5.01184,396,767 - 84,411,362 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41179,935,273 - 79,950,589 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1176,622,175 - 76,636,605 (+)NCBICelera
RGSC_v3.11179,992,852 - 80,008,178 (+)NCBI
Cytogenetic Map11q23NCBI
RFC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,789,900 - 186,806,482 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3186,789,880 - 186,807,058 (-)Ensemblhg38GRCh38
GRCh373186,507,689 - 186,524,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,990,375 - 188,006,984 (-)NCBIBuild 36Build 36hg18NCBI36
Build 343187,990,385 - 188,006,992NCBI
Celera3184,943,843 - 184,960,507 (-)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3183,917,358 - 183,933,324 (-)NCBIHuRef
CHM1_13186,471,258 - 186,488,062 (-)NCBICHM1_1
T2T-CHM13v2.03189,611,930 - 189,628,517 (-)NCBIT2T-CHM13v2.0
Rfc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,932,698 - 22,946,480 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1622,932,693 - 22,946,487 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381623,113,948 - 23,127,730 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1623,113,943 - 23,127,737 (-)Ensemblmm10GRCm38
MGSCv371623,114,021 - 23,127,803 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361623,029,282 - 23,043,064 (-)NCBIMGSCv36mm8
Celera1623,672,554 - 23,686,047 (-)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.93NCBI
Rfc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542020,948,549 - 20,967,845 (+)Ensembl
ChiLan1.0NW_00495542020,948,549 - 20,967,845 (+)NCBIChiLan1.0ChiLan1.0
RFC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22184,666,547 - 184,683,752 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13184,671,254 - 184,688,690 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03183,824,865 - 183,841,895 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13192,290,639 - 192,307,478 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,290,639 - 192,307,839 (-)EnsemblpanPan2panpan1.1
RFC4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,361,024 - 19,377,289 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,361,044 - 19,377,294 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3423,446,502 - 23,462,817 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03419,272,394 - 19,288,876 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3419,272,548 - 19,288,832 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13419,303,693 - 19,320,012 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03419,303,699 - 19,320,013 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03419,531,570 - 19,547,898 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rfc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,112,167 - 117,127,993 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365783,204,060 - 3,219,800 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365783,204,035 - 3,219,806 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RFC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,589,295 - 124,604,426 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113124,589,292 - 124,604,421 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213133,979,667 - 133,994,796 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RFC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11581,081,415 - 81,097,599 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1581,081,481 - 81,097,272 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604154,573,322 - 54,589,390 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rfc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473069,979,072 - 69,999,750 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473069,979,038 - 69,999,750 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rfc4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v147,904,743 - 7,918,859 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:13
Count of miRNA genes:13
Interacting mature miRNAs:13
Transcripts:ENSRNOT00000002487
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)119046178196556255Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)118295102896351019Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat

Markers in Region
RH134436  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21177,764,209 - 77,764,390 (+)MAPPERmRatBN7.2
Rnor_6.062,979,116 - 2,979,297NCBIRnor6.0
Rnor_6.01181,373,131 - 81,373,311NCBIRnor6.0
Rnor_5.01184,411,449 - 84,411,629UniSTSRnor5.0
RGSC_v3.41179,950,676 - 79,950,856UniSTSRGSC3.4
Celera1176,636,692 - 76,636,872UniSTS
Celera614,390,529 - 14,390,709UniSTS
Cytogenetic Map6q11UniSTS
Cytogenetic Map11q23UniSTS
D20S1005  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21177,764,527 - 77,764,607 (+)MAPPERmRatBN7.2
Rnor_6.01181,373,449 - 81,373,528NCBIRnor6.0
Rnor_5.01184,411,767 - 84,411,846UniSTSRnor5.0
RGSC_v3.41179,950,994 - 79,951,073UniSTSRGSC3.4
Celera1176,637,010 - 76,637,089UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002487   ⟹   ENSRNOP00000002487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1191,254,243 - 91,268,730 (+)Ensembl
mRatBN7.2 Ensembl1177,749,638 - 77,764,122 (+)Ensembl
Rnor_6.0 Ensembl1181,358,592 - 81,373,043 (+)Ensembl
RefSeq Acc Id: NM_001105869   ⟹   NP_001099339
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81191,254,273 - 91,268,727 (+)NCBI
mRatBN7.21177,749,670 - 77,764,123 (+)NCBI
Rnor_6.01181,358,592 - 81,373,044 (+)NCBI
Rnor_5.01184,396,767 - 84,411,362 (+)NCBI
RGSC_v3.41179,935,273 - 79,950,589 (+)RGD
Celera1176,622,175 - 76,636,605 (+)RGD
Sequence:
RefSeq Acc Id: XM_063270368   ⟹   XP_063126438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81191,254,446 - 91,268,727 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001099339 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126438 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68166 (Get FASTA)   NCBI Sequence Viewer  
  EDL78078 (Get FASTA)   NCBI Sequence Viewer  
  EDL78079 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002487
  ENSRNOP00000002487.4
RefSeq Acc Id: NP_001099339   ⟸   NM_001105869
- UniProtKB: B4F778 (UniProtKB/TrEMBL),   F7FPS8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002487   ⟸   ENSRNOT00000002487
RefSeq Acc Id: XP_063126438   ⟸   XM_063270368
- Peptide Label: isoform X1
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B4F778-F1-model_v2 AlphaFold B4F778 1-364 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698245
Promoter ID:EPDNEW_R8770
Type:multiple initiation site
Name:Rfc4_1
Description:replication factor C subunit 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01181,358,562 - 81,358,622EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310142 AgrOrtholog
BioCyc Gene G2FUF-20857 BioCyc
Ensembl Genes ENSRNOG00000001816 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002487 ENTREZGENE
  ENSRNOT00000002487.9 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  1.20.272.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro ATPase_AAA+_core UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  DNA_pol3_clamp-load_cplx_C UniProtKB/TrEMBL
  DNA_Rep/Repair_Clamp_Loader UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Replication_factor_C UniProtKB/TrEMBL
  RFC_lid UniProtKB/TrEMBL
KEGG Report rno:288003 UniProtKB/TrEMBL
NCBI Gene 288003 ENTREZGENE
PANTHER REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT UniProtKB/TrEMBL
  REPLICATION FACTOR C SUBUNIT 4 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  RCF1-5-like_lid UniProtKB/TrEMBL
  Rep_fac_C UniProtKB/TrEMBL
PhenoGen Rfc4 PhenoGen
RatGTEx ENSRNOG00000001816 RatGTEx
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP Pol_clamp_load_C UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt B4F778 ENTREZGENE, UniProtKB/TrEMBL
  F7FPS8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 Rfc4  replication factor C subunit 4  Rfc4  replication factor C (activator 1) 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Rfc4  replication factor C (activator 1) 4   Rfc4_predicted  replication factor C (activator 1) 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rfc4_predicted  replication factor C (activator 1) 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED