RFC4 (replication factor C (activator 1) 4, 37kDa)

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Keyword

Gene: RFC4 (replication factor C (activator 1) 4, 37kDa) Homo sapiens

Symbol:

RFC4

Name:

replication factor C (activator 1) 4, 37kDa

Description:

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

A1; A1 37 kDa subunit; activator 1 37 kDa subunit; activator 1 subunit 4; MGC27291; OTTHUMP00000210038; OTTHUMP00000210039; replication factor C 37 kDa subunit; replication factor C subunit 4; RF-C 37 kDa subunit; RFC 37 kDa subunit; RFC37

Orthologs:

Mus musculus : Rfc4 (replication factor C (activator 1) 4) MGI
Rattus norvegicus : Rfc4 (replication factor C (activator 1) 4)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	3	186,376,753 - 186,393,557	-	NCBI
Human Genome Assembly HuRef	3	183,917,358 - 183,933,324	-	NCBI
Human Genome Assembly GRCh37	3	186,507,681 - 186,524,484	-	NCBI
Human Genome Assembly Build 36	3	187,990,375 - 188,006,984	-	NCBI
Human Cytogenetic Map	3	q27		NCBI
Human Genome Assembly	3	187,990,385 - 188,006,992		NCBI